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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Role of WNT10A in failure of tooth development in humans and zebrafish
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Citation:
Mol Genet Genomic Med. 2017 Nov;5(6):730-741. doi: 10.1002/mgg3.332. Epub 2017 Sep 14 Epub:
Not Epub Abstract:
BACKGROUND: Oligodontia is a severe form of tooth agenesis characterized by the absence of six or more permanent teeth.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yuan Q, Zhao M, Tandon B, Maili L, Liu X, Zhang A, Baugh EH, Tran T, Silva RM, Hecht JT, Swindell EC, Wagner DS, Letra A. Role of WNT10A in failure of tooth development in humans and zebrafish. Mol Genet Genomic Med. 2017 Nov;5(6):730-741. doi: 10.1002/mgg3.332. Epub 2017 Sep 14. |
Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development
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Citation:
J Mol Cell Cardiol. 2017 Nov 22. pii: S0022-2828(17)30348-6. doi: 10.1016/j.yjmcc.2017.11.013. [Epub ahead of print] Epub:
Yes Abstract:
TBX5 plays a critical role in heart and forelimb development. Mutations in TBX5 cause Holt-Oram syndrome, an autosomal dominant... Organism or Cell Type:
zebrafish Citation Extract: Ghosh TK, Aparicio-Sánchez JJ, Buxton S, Ketley A, Mohamed T, Rutland CS, Loughna S, Brook JD. Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development. J Mol Cell Cardiol. 2017 Nov 22. pii: S0022-2828(17)30348-6. doi: 10.1016/j.yjmcc.2017.11.013. [Epub ahead of print]. |
Protein localization screening in vivo reveals novel regulators of multiciliated cell development and function
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Citation:
J Cell Sci. 2017;[Epub ahead of print] doi:10.1242/jcs.206565 Epub:
Yes Abstract:
Multiciliated cells (MCCs) drive fluid flow in diverse tubular organs and are essential for the development and homeostasis of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Fan Tu, Jakub Sedzinski, Yun Ma, Edward M. Marcotte, John B. Wallingford. Protein localization screening in vivo reveals novel regulators of multiciliated cell development and function. J Cell Sci. 2017;[Epub ahead of print] doi:10.1242/jcs.206565. |
Evolutionary recruitment of flexible Esrp-dependent splicing programs into diverse embryonic morphogenetic processes
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Citation:
Nat Comm. 2017;8:1799. doi:10.1038/s41467-017-01961-y Epub:
Not Epub Abstract:
Epithelial-mesenchymal interactions are crucial for the development of numerous animal structures. Thus, unraveling how... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Burguera D, Marquez Y, Racioppi C, Permanyer J, Torres-Méndez A, Esposito R, Albuixech-Crespo B, Fanlo L, D’Agostino Y, Gohr A, Navas-Perez E, Riesgo A, Cuomo C, Benvenuto G, Christiaen LA, Martí E, D’Aniello S, Spagnuolo A, Ristoratore F, Arnone MI, Garcia-Fernàndez J, Irimia M. Evolutionary recruitment of flexible Esrp-dependent splicing programs into diverse embryonic morphogenetic processes. Nat Comm. 2017;8:1799. doi:10.1038/s41467-017-01961-y. |
The oncogenic transcription factor ERG represses the transcription of the tumour suppressor gene PTEN in prostate cancer cells
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Citation:
Oncol Lett. 2017 Nov;14(5):5605-5610. doi: 10.3892/ol.2017.6841. Epub 2017 Aug 28 Epub:
Not Epub Abstract:
The oncogene ETS-related gene (ERG) encodes a transcription factor with roles in the regulation of haematopoiesis, angiogenesis... Delivery Method:
Vivo-Morpholino + Endo-Porter Organism or Cell Type:
cell culture: VCaP (ATCC CRL-2876) Citation Extract: Adamo P, Porazinski S, Rajatileka S, Jumbe S, Hagen R, Cheung MK, Wilson I, Ladomery MR. The oncogenic transcription factor ERG represses the transcription of the tumour suppressor gene PTEN in prostate cancer cells. Oncol Lett. 2017 Nov;14(5):5605-5610. doi: 10.3892/ol.2017.6841. Epub 2017 Aug 28. |
MYC targeted long non-coding RNA DANCR promotes cancer in part by reducing p21 levels
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Citation:
Cancer Res. 2017;[Epub ahead of print] doi:10.1158/0008-5472 Epub:
Yes Abstract:
The MYC oncogene broadly promotes transcription mediated by all nuclear RNA polymerases, thereby acting as a positive modifier... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: P493-6 Citation Extract: Lu Y, Hu Z, Mangala LS, Stine ZE, Hu X, Jiang D, Xiang Y, Zhang Y, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Demarzo A, Sood AK, Zhang L, Dang CV. MYC targeted long non-coding RNA DANCR promotes cancer in part by reducing p21 levels. Cancer Res. 2017;[Epub ahead of print] doi:10.1158/0008-5472. |
Identification of Isthmin 1 as a Novel Clefting and Craniofacial Patterning Gene in Humans
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Citation:
Genetics. 2017;[Epub ahead of print] doi:10.1534/genetics.117.300535 Epub:
Yes Abstract:
Orofacial clefts are one of the most common birth defects, affecting 1-2 per 1000 births, and have a complex etiology. High-... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Lansdon LA, Darbro BW, Petrin AL, Hulstrand AM, Standley JM, Brouillette RB, Long A, Mansilla MA, Cornell RA, Murray JC, Houston DW, Manak R. Identification of Isthmin 1 as a Novel Clefting and Craniofacial Patterning Gene in Humans. Genetics. 2017;[Epub ahead of print] doi:10.1534/genetics.117.300535. |
Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome
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Citation:
Nat Comm. 2017;8:1696. doi:10.1038/s41467-017-01630-0 Epub:
Not Epub Abstract:
Patients with short QT syndrome (SQTS) may present with syncope, ventricular fibrillation or sudden cardiac death. Six SQTS... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Thorsen K, Dam VS, Kjaer-Sorensen K, Pedersen LN, Skeberdis VA, Jurevičius J, Treinys R, Petersen IMBS, Nielsen MS, Oxvig C, Morth JP, Matchkov VV, Aalkjær C, Bundgaard H, Jensen HK. Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome. Nat Comm. 2017;8:1696. doi:10.1038/s41467-017-01630-0. |
Knockdown of Laminin gamma-3 (Lamc3) impairs motoneuron guidance in the zebrafish embryo
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Citation:
Wellcome Open Res. 2017 Nov 16;2:111. doi: 10.12688/wellcomeopenres.12394.1. eCollection 2017 Epub:
Not Epub Abstract:
Background: Previous work in the zebrafish embryo has shown that laminin γ-3 ( lamc3) is enriched in endothelial cells marked... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Eve AMJ, Smith JC
. Knockdown of Laminin gamma-3 (Lamc3) impairs motoneuron guidance in the zebrafish embryo. Wellcome Open Res. 2017 Nov 16;2:111. doi: 10.12688/wellcomeopenres.12394.1. eCollection 2017. |
Gdf3 is required for robust Nodal signaling during germ layer formation and left-right patterning
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Citation:
eLife. 2017;6:e28635 doi:10.7554/eLife.28635 Epub:
Not Epub Abstract:
Vertebrate embryonic patterning depends on signaling from Nodal, a TGFβ superfamily member. There are three Nodal orthologs in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pelliccia JL, Jindal GA, Burdine RD. Gdf3 is required for robust Nodal signaling during germ layer formation and left-right patterning. eLife. 2017;6:e28635 doi:10.7554/eLife.28635. |