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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

G protein-coupled receptor gpr34l mutation affects thrombocyte function in zebrafish

Authors:
Kim S, Alsrhani A, Zafreen L, Khandekar G, Marlow FL, Abrams EW, Mullins MC, Jagadeeswaran P
Citation:
Br J Haematol. 2017 Dec 21. doi: 10.1111/bjh.15046. [Epub ahead of print]
Epub:
Yes
Abstract:
Haemostasis is a defence mechanism that has evolved to protect organisms from losing their circulating fluid. We have...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Kim S, Alsrhani A, Zafreen L, Khandekar G, Marlow FL, Abrams EW, Mullins MC, Jagadeeswaran P. G protein-coupled receptor gpr34l mutation affects thrombocyte function in zebrafish. Br J Haematol. 2017 Dec 21. doi: 10.1111/bjh.15046. [Epub ahead of print].

RNA helicase Mov10 is essential for gastrulation and CNS development

Authors:
Skariah G, Perry KJ, Drnevich J, Henry JJ, Ceman S
Citation:
Dev Dyn. 2017 Dec 21. doi: 10.1002/dvdy.24615. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Mov10 is an RNA helicase that modulates access of Argonaute 2 to microRNA recognition elements in mRNAs. We...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Skariah G, Perry KJ, Drnevich J, Henry JJ, Ceman S. RNA helicase Mov10 is essential for gastrulation and CNS development. Dev Dyn. 2017 Dec 21. doi: 10.1002/dvdy.24615. [Epub ahead of print].

Epigenetic Regulators Modulate Muscle Damage in Duchenne Muscular Dystrophy Model

Authors:
Bajanca F, Vandel L
Citation:
PLOS Currents Muscular Dystrophy. 2017. Edition 1. doi:10.1371/currents.md.f1e2379fa632f8135577333dd92ca83b
Epub:
Not Epub
Abstract:
Histone acetyl transferases (HATs) and histone deacetylases (HDAC) control transcription during myogenesis. HDACs promote...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bajanca F, Vandel L. Epigenetic Regulators Modulate Muscle Damage in Duchenne Muscular Dystrophy Model. PLOS Currents Muscular Dystrophy. 2017. Edition 1. doi:10.1371/currents.md.f1e2379fa632f8135577333dd92ca83b.

Tris(1,3-dichloro-2-propyl) phosphate disrupts dorsoventral patterning in zebrafish embryos

Authors:
Dasgupta S, Vliet SM, Kupsco A, Leet JK, Altomare D, Volz DC
Citation:
PeerJ. 2017 Dec 14;5:e4156. doi: 10.7717/peerj.4156. eCollection 2017
Epub:
Not Epub
Abstract:
Tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) is a high-production volume organophosphate flame retardant widely used within...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dasgupta S, Vliet SM, Kupsco A, Leet JK, Altomare D, Volz DC. Tris(1,3-dichloro-2-propyl) phosphate disrupts dorsoventral patterning in zebrafish embryos. PeerJ. 2017 Dec 14;5:e4156. doi: 10.7717/peerj.4156. eCollection 2017.

Vivo-morpholino oligomers strongly inhibit dengue virus replication and production

Authors:
Phumesin P, Junking M, Panya A, Yongpitakwattana P, Noisakran S, Limjindaporn T, Yenchitsomanus P
Citation:
Arch Virol. 2017;[Epub ahead of print] doi:10.1007/s00705-017-3666-9
Epub:
Yes
Abstract:
Dengue virus (DENV) infection is a worldwide public health problem, which can cause severe dengue hemorrhagic fever (DHF) and...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: Vero, A549, U937, primary human monocytes
Citation Extract:
Phumesin P, Junking M, Panya A, Yongpitakwattana P, Noisakran S, Limjindaporn T, Yenchitsomanus P. Vivo-morpholino oligomers strongly inhibit dengue virus replication and production. Arch Virol. 2017;[Epub ahead of print] doi:10.1007/s00705-017-3666-9.

Xom induces proteolysis of β-catenin through GSK3β-mediated pathway

Authors:
Wu B, Gao H, Le Y, Wu X, Zhu Z
Citation:
FEBS Lett. 2017 Dec 18. doi: 10.1002/1873-3468.12949. [Epub ahead of print]
Epub:
Yes
Abstract:
The dorsal cell fate determination factor β-catenin and its antagonist, the ventral cell fate determination factor Xom, are...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Wu B, Gao H, Le Y, Wu X, Zhu Z. Xom induces proteolysis of β-catenin through GSK3β-mediated pathway. FEBS Lett. 2017 Dec 18. doi: 10.1002/1873-3468.12949. [Epub ahead of print].

Ribosome biogenesis protein Urb1 acts downstream of mTOR complex 1 to modulate digestive organ development in zebrafish

Authors:
He J, Yang Y, Zhang J, Chen J, Wei X, He J, Luo L
Citation:
J Genet Genomics. 2017 Nov 29. pii: S1673-8527(17)30198-4. doi: 10.1016/j.jgg.2017.09.013. [Epub ahead of print]
Epub:
Yes
Abstract:
Ribosome biogenesis is essential for the cell growth and division. Disruptions in ribosome biogenesis result in developmental...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
He J, Yang Y, Zhang J, Chen J, Wei X, He J, Luo L. Ribosome biogenesis protein Urb1 acts downstream of mTOR complex 1 to modulate digestive organ development in zebrafish. J Genet Genomics. 2017 Nov 29. pii: S1673-8527(17)30198-4. doi: 10.1016/j.jgg.2017.09.013. [Epub ahead of print].

Tween 85-Modified Low Molecular Weight PEI Enhances Exon-Skipping of Antisense Morpholino Oligomer In Vitro and in mdx Mice

Authors:
Wang M, Wu B, Tucker JD, Shah SN, Lu P, Bollinger LE, Lu Q
Citation:
Mol Ther Nucleic Acids. 2017 Dec 15;9:120-131. doi: 10.1016/j.omtn.2017.09.006. Epub 2017 Sep 20
Epub:
Not Epub
Abstract:
We investigated a series of Tween 85 modified low molecular weight polyethylenimine (LPEI, 0.8k/1.2k/2.0k)-copolymers (Zs)...
Delivery Method:
Tween 85-Modified PEI, Endo-Porter (delivery control)
Organism or Cell Type:
cell culture: C2C12E50, C2C12E23; mdx mice
Citation Extract:
Wang M, Wu B, Tucker JD, Shah SN, Lu P, Bollinger LE, Lu Q. Tween 85-Modified Low Molecular Weight PEI Enhances Exon-Skipping of Antisense Morpholino Oligomer In Vitro and in mdx Mice. Mol Ther Nucleic Acids. 2017 Dec 15;9:120-131. doi: 10.1016/j.omtn.2017.09.006. Epub 2017 Sep 20.

Mecp2 regulates tnfa during zebrafish embryonic development and acute inflammation

Authors:
van der Vaart M, Svoboda O, Weijts BG, Espín-Palazón R, Sapp V, Pietri T, Bagnat M, Muotri AR, Traver D
Citation:
Dis Model Mech. 2017 Oct 9. pii: dmm.026922. doi: 10.1242/dmm.026922. [Epub ahead of print]
Epub:
Yes
Abstract:
Mutations in MECP2 cause Rett syndrome, a severe neurological disorder with autism-like features. Duplication of MECP2 also...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
van der Vaart M, Svoboda O, Weijts BG, Espín-Palazón R, Sapp V, Pietri T, Bagnat M, Muotri AR, Traver D. Mecp2 regulates tnfa during zebrafish embryonic development and acute inflammation. Dis Model Mech. 2017 Oct 9. pii: dmm.026922. doi: 10.1242/dmm.026922. [Epub ahead of print].

Notch-mediated lateral inhibition is an evolutionarily conserved mechanism patterning the ectoderm in echinoids

Authors:
Erkenbrack EM
Citation:
Dev Genes Evol. 2017;{Epub ahead or print] doi:10.1007/s00427-017-0599-y
Epub:
Yes
Abstract:
Notch signaling is a crucial cog in early development of euechinoid sea urchins, specifying both non-skeletogenic mesodermal...
Delivery Method:
microinjection
Organism or Cell Type:
Eucidaris tribuloides (sea urchin)
Citation Extract:
Erkenbrack EM. Notch-mediated lateral inhibition is an evolutionarily conserved mechanism patterning the ectoderm in echinoids. Dev Genes Evol. 2017;{Epub ahead or print] doi:10.1007/s00427-017-0599-y.

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