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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

The function of tcf3 in medaka embryos: efficient knockdown with pePNAs

Authors:
Doenz G, Dorn S, Aghaallaei N, Bajoghli B, Riegel E, Aigner M, Bock H, Werner B, Lindhorst T, Czerny T
Citation:
BMC Biotechnol. 2018 Jan 9;18(1):1. doi: 10.1186/s12896-017-0411-0
Epub:
Not Epub
Abstract:
BACKGROUND: The application of antisense molecules, such as morpholino oligonucleotides, is an efficient method of gene...
Link:
https://bmcbiotechnol.biomedcentral.com/articles/10.1186/s12896-017-0411-0
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Doenz G, Dorn S, Aghaallaei N, Bajoghli B, Riegel E, Aigner M, Bock H, Werner B, Lindhorst T, Czerny T. The function of tcf3 in medaka embryos: efficient knockdown with pePNAs. BMC Biotechnol. 2018 Jan 9;18(1):1. doi: 10.1186/s12896-017-0411-0.

Independent modes of ganglion cell translocation ensure correct lamination of the zebrafish retina

Authors:
Icha J, Kunath C, Rocha-Martins M, Norden C
Citation:
J Cell Biol. 2016 Oct 24;215(2):259-275
Epub:
Not Epub
Abstract:
The arrangement of neurons into distinct layers is critical for neuronal connectivity and function. During development, most...
Link:
http://jcb.rupress.org/content/215/2/259
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Icha J, Kunath C, Rocha-Martins M, Norden C. Independent modes of ganglion cell translocation ensure correct lamination of the zebrafish retina. J Cell Biol. 2016 Oct 24;215(2):259-275.

Functional divergence of paralogous transcription factors supported the evolution of biomineralization in echinoderms

Authors:
Khor JM, Ettensohn CA
Citation:
Elife. 2017 Nov 20;6. pii: e32728. doi: 10.7554/eLife.32728
Epub:
Not Epub
Abstract:
Alx1 is a pivotal transcription factor in a gene regulatory network that controls skeletogenesis throughout the echinoderm...
Link:
https://elifesciences.org/articles/32728
Delivery Method:
microinjection
Organism or Cell Type:
Lytechnius variegatus (sea urchin)
Citation Extract:
Khor JM, Ettensohn CA. Functional divergence of paralogous transcription factors supported the evolution of biomineralization in echinoderms. Elife. 2017 Nov 20;6. pii: e32728. doi: 10.7554/eLife.32728.

In Vivo Function of the Chaperonin TRiC in α-Actin Folding during Sarcomere Assembly

Authors:
Berger J, Berger S, Li M, Jacoby AS, Arner A, Bavi N, Stewart AG, Currie PD
Citation:
Cell Rep. 2018;22(2):313-22. doi:10.1016/j.celrep.2017.12.069
Epub:
Not Epub
Abstract:
The TCP-1 ring complex (TRiC) is a multi-subunit group II chaperonin that assists nascent or misfolded proteins to attain their...
Link:
http://www.cell.com/cell-reports/fulltext/S2211-1247(17)31906-X
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Berger J, Berger S, Li M, Jacoby AS, Arner A, Bavi N, Stewart AG, Currie PD. In Vivo Function of the Chaperonin TRiC in α-Actin Folding during Sarcomere Assembly. Cell Rep. 2018;22(2):313-22. doi:10.1016/j.celrep.2017.12.069.

Protease signaling regulates apical cell extrusion, cell contacts, and proliferation in epithelia

Authors:
Schepis A, Barker A, Srinivasan Y, Balouch E, Zheng Y, Lam I, Clay H, Hsiao CD, Coughlin SR
Citation:
J Cell Biol. 2018 Jan 4. pii: jcb.201709118. doi: 10.1083/jcb.201709118. [Epub ahead of print]
Epub:
Yes
Abstract:
Mechanisms that sense and regulate epithelial morphogenesis, integrity, and homeostasis are incompletely understood. Protease-...
Link:
http://jcb.rupress.org/content/early/2018/01/03/jcb.201709118.long
Organism or Cell Type:
zebrafish
Citation Extract:
Schepis A, Barker A, Srinivasan Y, Balouch E, Zheng Y, Lam I, Clay H, Hsiao CD, Coughlin SR. Protease signaling regulates apical cell extrusion, cell contacts, and proliferation in epithelia. J Cell Biol. 2018 Jan 4. pii: jcb.201709118. doi: 10.1083/jcb.201709118. [Epub ahead of print].

Cell-type heterogeneity in the early zebrafish olfactory epithelium is generated from progenitors within preplacodal ectoderm

Authors:
Aguillon R, Batut J, Subramanian A, Madelaine R, Dufourcq P, Schilling TF, Blader P
Citation:
Elife. 2018 Jan 2;7. pii: e32041. doi: 10.7554/eLife.32041
Epub:
Not Epub
Abstract:
The zebrafish olfactory epithelium comprises a variety of neuronal populations, which are thought to have distinct embryonic...
Link:
https://elifesciences.org/articles/32041
Organism or Cell Type:
zebrafish
Citation Extract:
Aguillon R, Batut J, Subramanian A, Madelaine R, Dufourcq P, Schilling TF, Blader P. Cell-type heterogeneity in the early zebrafish olfactory epithelium is generated from progenitors within preplacodal ectoderm. Elife. 2018 Jan 2;7. pii: e32041. doi: 10.7554/eLife.32041.

Cohesin facilitates zygotic genome activation in zebrafish

Authors:
Meier M, Grant J, Dowdle A, Thomas A, Gerton J, Collas P, O'Sullivan JM, Horsfield JA
Citation:
Development. 2018 Jan 3;145(1). pii: dev156521. doi: 10.1242/dev.156521
Epub:
Not Epub
Abstract:
At zygotic genome activation (ZGA), changes in chromatin structure are associated with new transcription immediately following...
Link:
http://dev.biologists.org/content/145/1/dev156521
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Meier M, Grant J, Dowdle A, Thomas A, Gerton J, Collas P, O'Sullivan JM, Horsfield JA. Cohesin facilitates zygotic genome activation in zebrafish. Development. 2018 Jan 3;145(1). pii: dev156521. doi: 10.1242/dev.156521.

Functional characterization of the mucus barrier on the Xenopus tropicalis skin surface

Authors:
Dubaissi E, Rousseau K, Hughes GW, Ridley C, Grencis RK, Roberts IS, Thornton DJ
Citation:
PNAS USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1713539115
Epub:
Yes
Abstract:
Mucosal surfaces represent critical routes for entry and exit of pathogens. As such, animals have evolved strategies to combat...
Link:
http://www.pnas.org/content/early/2018/01/03/1713539115
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Dubaissi E, Rousseau K, Hughes GW, Ridley C, Grencis RK, Roberts IS, Thornton DJ. Functional characterization of the mucus barrier on the Xenopus tropicalis skin surface. PNAS USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1713539115.

Rapid detection of exosomal microRNA biomarkers by electrokinetic concentration for liquid biopsy on chip

Authors:
Cheung LS, Wei X, Martins D, Song Y-A
Citation:
Biomicrofluidics. 2018;12:014104. doi:10.1063/1.5009719
Epub:
Not Epub
Abstract:
An ion concentration polarization (ICP)-based electrokinetic concentration device is used for accelerating the surface...
Link:
http://aip.scitation.org/doi/10.1063/1.5009719
Citation Extract:
Cheung LS, Wei X, Martins D, Song Y-A. Rapid detection of exosomal microRNA biomarkers by electrokinetic concentration for liquid biopsy on chip. Biomicrofluidics. 2018;12:014104. doi:10.1063/1.5009719.

A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism

Authors:
Swinnen B, Bento-Abreu A, Gendron TF, Boeynaems S, Bogaert E, Nuyts R, Timmers M, Scheveneels W, Hersmus N, Wang J, Mizielinska S, Isaacs AM, Petrucelli L, Lemmens R, Van Damme P, Van Den Bosch L, Robberecht W
Citation:
Acta Neuropathol. 2018 Jan 4. doi: 10.1007/s00401-017-1796-5. [Epub ahead of print]
Epub:
Yes
Abstract:
The exact mechanism underlying amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) associated with the GGGGCC...
Link:
https://link.springer.com/article/10.1007%2Fs00401-017-1796-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Swinnen B, Bento-Abreu A, Gendron TF, Boeynaems S, Bogaert E, Nuyts R, Timmers M, Scheveneels W, Hersmus N, Wang J, Mizielinska S, Isaacs AM, Petrucelli L, Lemmens R, Van Damme P, Van Den Bosch L, Robberecht W. A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism. Acta Neuropathol. 2018 Jan 4. doi: 10.1007/s00401-017-1796-5. [Epub ahead of print].

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