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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Usher syndrome type 1-associated cadherins shape the photoreceptor outer segment

Authors:
Schietroma C, Parain K, Estivalet A, Aghaie A, Boutet de Monvel J, Picaud S, Sahel JA, Perron M, El-Amraoui A, Petit C
Citation:
J Cell Biol. 2017 Jun 5;216(6):1849-1864. doi: 10.1083/jcb.201612030. Epub 2017 May 11
Epub:
Not Epub
Abstract:
Usher syndrome type 1 (USH1) causes combined hearing and sight defects, but how mutations in USH1 genes lead to retinal...
Link:
http://jcb.rupress.org/content/216/6/1849
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Schietroma C, Parain K, Estivalet A, Aghaie A, Boutet de Monvel J, Picaud S, Sahel JA, Perron M, El-Amraoui A, Petit C. Usher syndrome type 1-associated cadherins shape the photoreceptor outer segment. J Cell Biol. 2017 Jun 5;216(6):1849-1864. doi: 10.1083/jcb.201612030. Epub 2017 May 11.

Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish

Authors:
Reig G, Cerda M, Sepúlveda N, Flores D, Castañeda V, Tada M, Härtel S, Concha ML
Citation:
Nat Commun. 2017 Jun 5;8:15431. doi: 10.1038/ncomms15431
Epub:
Not Epub
Abstract:
The spreading of mesenchymal-like cell layers is critical for embryo morphogenesis and tissue repair, yet we know little of...
Link:
https://www.nature.com/articles/ncomms15431
Delivery Method:
microinjection
Organism or Cell Type:
Austrolebias nigripinnis (killifish)
Citation Extract:
Reig G, Cerda M, Sepúlveda N, Flores D, Castañeda V, Tada M, Härtel S, Concha ML. Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish. Nat Commun. 2017 Jun 5;8:15431. doi: 10.1038/ncomms15431.

Functional analysis of a novel protein, Pierce1, in motile ciliogenesis in mammalian airway epithelial cells and zebrafish embryos

Authors:
Anujan P, Roy S, Bingle CD
Citation:
Mech Dev. 2017;145 Suppl:S25(PS1.5). doi:10.1016/j.mod.2017.04.012
Epub:
Not Epub
Abstract:
No abstract available
Link:
http://www.sciencedirect.com/science/article/pii/S0925477317300953
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Anujan P, Roy S, Bingle CD. Functional analysis of a novel protein, Pierce1, in motile ciliogenesis in mammalian airway epithelial cells and zebrafish embryos. Mech Dev. 2017;145 Suppl:S25(PS1.5). doi:10.1016/j.mod.2017.04.012.

Genome-wide use of high- and low-affinity Tbrain transcription factor binding sites during echinoderm development

Authors:
Cary GA, Cheatle Jarvela AM, Francolini RD, Hinman VF
Citation:
Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):5854-5861. doi: 10.1073/pnas.1610611114
Epub:
Not Epub
Abstract:
Sea stars and sea urchins are model systems for interrogating the types of deep evolutionary changes that have restructured...
Link:
http://www.pnas.org/content/114/23/5854.full
Delivery Method:
microinjection
Organism or Cell Type:
Patiria miniata (sea star)
Citation Extract:
Cary GA, Cheatle Jarvela AM, Francolini RD, Hinman VF. Genome-wide use of high- and low-affinity Tbrain transcription factor binding sites during echinoderm development. Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):5854-5861. doi: 10.1073/pnas.1610611114.

Anti-metastatic outcome of isoform-specific prolactin receptor targeting in breast cancer

Authors:
Yonezawa T, Chen KH, Ghosh MK, Rivera L, Dill R, Ma L, Villa PA, Kawaminami M, Walker AM
Citation:
Cancer Lett. 2015 Sep 28;366(1):84-92. doi: 10.1016/j.canlet.2015.06.010. Epub 2015 Jun 18
Epub:
Not Epub
Abstract:
Controversy exists concerning the role of the long prolactin receptor (PRLR) in the progression of breast cancer. By targeting...
Link:
http://www.cancerletters.info/article/S0304-3835(15)00402-4/fulltext
Delivery Method:
Alzet osmotic pump
Organism or Cell Type:
mice with human xenograft tumors
Citation Extract:
Yonezawa T, Chen KH, Ghosh MK, Rivera L, Dill R, Ma L, Villa PA, Kawaminami M, Walker AM. Anti-metastatic outcome of isoform-specific prolactin receptor targeting in breast cancer. Cancer Lett. 2015 Sep 28;366(1):84-92. doi: 10.1016/j.canlet.2015.06.010. Epub 2015 Jun 18.

An oxygen-insensitive Hif-3α isoform inhibits Wnt signaling by destabilizing the nuclear β-catenin complex

Authors:
Zhang P, Bai Y, Lu L, Li Y, Duan C
Citation:
Elife. 2016 Jan 14;5. pii: e08996. doi: 10.7554/eLife.08996
Epub:
Not Epub
Abstract:
Hypoxia-inducible factors (HIFs), while best known for their roles in the hypoxic response, have oxygen-independent roles in...
Link:
https://elifesciences.org/articles/08996
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang P, Bai Y, Lu L, Li Y, Duan C. An oxygen-insensitive Hif-3α isoform inhibits Wnt signaling by destabilizing the nuclear β-catenin complex. Elife. 2016 Jan 14;5. pii: e08996. doi: 10.7554/eLife.08996.

SPOP mutation leads to genomic instability in prostate cancer

Authors:
Boysen G, Barbieri CE, Prandi D, Blattner M, Chae SS, Dahija A, Nataraj S, Huang D, Marotz C, Xu L, Huang J, Lecca P, Chhangawala S, Liu D, Zhou P, Sboner A, de Bono JS, Demichelis F, Houvras Y, Rubin MA
Citation:
Elife. 2015 Sep 16;4. pii: e09207. doi: 10.7554/eLife.09207
Epub:
Not Epub
Abstract:
Genomic instability is a fundamental feature of human cancer often resulting from impaired genome maintenance. In prostate...
Link:
https://elifesciences.org/articles/09207
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boysen G, Barbieri CE, Prandi D, Blattner M, Chae SS, Dahija A, Nataraj S, Huang D, Marotz C, Xu L, Huang J, Lecca P, Chhangawala S, Liu D, Zhou P, Sboner A, de Bono JS, Demichelis F, Houvras Y, Rubin MA. SPOP mutation leads to genomic instability in prostate cancer. Elife. 2015 Sep 16;4. pii: e09207. doi: 10.7554/eLife.09207.

Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit

Authors:
Hatzold J, Beleggia F, Herzig H, Altmüller J, Nürnberg P, Bloch W, Wollnik B, Hammerschmidt M
Citation:
Elife. 2016 May 30;5. pii: e14277. doi: 10.7554/eLife.14277
Epub:
Not Epub
Abstract:
The molecular pathways underlying tumor suppression are incompletely understood. Here, we identify cooperative non-cell-...
Link:
https://elifesciences.org/articles/14277v3
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hatzold J, Beleggia F, Herzig H, Altmüller J, Nürnberg P, Bloch W, Wollnik B, Hammerschmidt M. Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit. Elife. 2016 May 30;5. pii: e14277. doi: 10.7554/eLife.14277.

IL17 factors are early regulators in the gut epithelium during inflammatory response to Vibrio in the sea urchin larva

Authors:
Buckley KM, Ho ECH, Hibino T, Schrankel CS, Schuh NW, Wang G, Rast JP
Citation:
Elife. 2017 Apr 27;6. pii: e23481. doi: 10.7554/eLife.23481
Epub:
Not Epub
Abstract:
IL17 cytokines are central mediators of mammalian immunity. In vertebrates, these factors derive from diverse cellular sources...
Link:
https://elifesciences.org/articles/23481
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Buckley KM, Ho ECH, Hibino T, Schrankel CS, Schuh NW, Wang G, Rast JP. IL17 factors are early regulators in the gut epithelium during inflammatory response to Vibrio in the sea urchin larva. Elife. 2017 Apr 27;6. pii: e23481. doi: 10.7554/eLife.23481.

The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo

Authors:
Sant KE, Hansen JM, Williams LM, Tran NL, Goldstone JV, Stegeman JJ, Hahn ME, Timme-Laragy A
Citation:
Redox Biol. 2017 May 30;13:207-218. doi: 10.1016/j.redox.2017.05.023. [Epub ahead of print]
Epub:
Yes
Abstract:
Redox signaling is important for embryogenesis, guiding pathways that govern processes crucial for embryo patterning, including...
Link:
http://www.sciencedirect.com/science/article/pii/S2213231717302409
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sant KE, Hansen JM, Williams LM, Tran NL, Goldstone JV, Stegeman JJ, Hahn ME, Timme-Laragy A. The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo. Redox Biol. 2017 May 30;13:207-218. doi: 10.1016/j.redox.2017.05.023. [Epub ahead of print].

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