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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Fine-tune regulation of carboxypeptidase N1 controls vascular patterning during zebrafish development

Authors:
Wu T-Y, Wang Y-S, Song Y-C, Chen Z-Y, Chen Y-T, Chiu C-C, Wu C-Y
Citation:
Sci Rep. 2017;7:1852 doi:10.1038/s41598-017-01976-x
Epub:
Not Epub
Abstract:
Vascular development is regulated by complicated signals and molecules in vertebrates. In this study, we characterized a novel...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu T-Y, Wang Y-S, Song Y-C, Chen Z-Y, Chen Y-T, Chiu C-C, Wu C-Y. Fine-tune regulation of carboxypeptidase N1 controls vascular patterning during zebrafish development. Sci Rep. 2017;7:1852 doi:10.1038/s41598-017-01976-x.

Knockdown of Hepatic Gonadotropin-Releasing Hormone by Vivo-Morpholino Decreases Liver Fibrosis in Multidrug Resistance Gene 2 Knockout Mice by Down-Regulation of miR-200b

Authors:
Kyritsi, Meng, Zhou, Wu, Venter J, Francis H, Kennedy L, Onori P, Franchitto A, Bernuzzi F, Invernizzi P, McDaniel K, Mancinelli R, Alvaro D, Gaudio E, Alpini G, Glaser S
Citation:
Am J Pathol. 2017;[Epub ahead of print] doi:10.1016/j.ajpath.2017.03.013
Epub:
Yes
Abstract:
Hepatic fibrosis occurs during the progression of primary sclerosing cholangitis (PSC) and is characterized by accumulation of...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Kyritsi, Meng, Zhou, Wu, Venter J, Francis H, Kennedy L, Onori P, Franchitto A, Bernuzzi F, Invernizzi P, McDaniel K, Mancinelli R, Alvaro D, Gaudio E, Alpini G, Glaser S. Knockdown of Hepatic Gonadotropin-Releasing Hormone by Vivo-Morpholino Decreases Liver Fibrosis in Multidrug Resistance Gene 2 Knockout Mice by Down-Regulation of miR-200b. Am J Pathol. 2017;[Epub ahead of print] doi:10.1016/j.ajpath.2017.03.013.

MicroRNA-203a regulates fast muscle differentiation by targeting dmrt2a in zebrafish embryos

Authors:
Lu C, Wu J, Xiong S, Zhang X, Zhang J, Mei J
Citation:
Gene. 2017 May 5. pii: S0378-1119(17)30335-9. doi: 10.1016/j.gene.2017.05.012. [Epub ahead of print]
Epub:
Yes
Abstract:
Dmrt2b (doublesex and mab-3 related transcription factor 2b) has been revealed to be involved in zebrafish slow muscle...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu C, Wu J, Xiong S, Zhang X, Zhang J, Mei J. MicroRNA-203a regulates fast muscle differentiation by targeting dmrt2a in zebrafish embryos. Gene. 2017 May 5. pii: S0378-1119(17)30335-9. doi: 10.1016/j.gene.2017.05.012. [Epub ahead of print].

Comparison of molecular marker expression in early zebrafish brain development following chronic ethanol or morpholino treatment

Authors:
Zhang C, Boa-Amponsem O, Cole GJ
Citation:
Exp Brain Res. 2017 May 10. doi: 10.1007/s00221-017-4977-5. [Epub ahead of print]
Epub:
Yes
Abstract:
This study was undertaken to ascertain whether defined markers of early zebrafish brain development are affected by chronic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang C, Boa-Amponsem O, Cole GJ. Comparison of molecular marker expression in early zebrafish brain development following chronic ethanol or morpholino treatment. Exp Brain Res. 2017 May 10. doi: 10.1007/s00221-017-4977-5. [Epub ahead of print].

Podocytes regulate the glomerular basement membrane protein nephronectin by means of miR-378a-3p in glomerular diseases

Authors:
Müller-Deile J, Dannenberg J, Schroder P, Lin MH, Miner JH, Chen R, Bräsen JH, Thum T, Nyström J, Staggs LB, Haller H, Fiedler J, Lorenzen JM, Schiffer M
Citation:
Kidney Int. 2017 May 2. pii: S0085-2538(17)30177-1. doi: 10.1016/j.kint.2017.03.005. [Epub ahead of print]
Epub:
Yes
Abstract:
The pathophysiology of many proteinuric kidney diseases is poorly understood, and microRNAs (miRs) regulation of these diseases...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Müller-Deile J, Dannenberg J, Schroder P, Lin MH, Miner JH, Chen R, Bräsen JH, Thum T, Nyström J, Staggs LB, Haller H, Fiedler J, Lorenzen JM, Schiffer M. Podocytes regulate the glomerular basement membrane protein nephronectin by means of miR-378a-3p in glomerular diseases. Kidney Int. 2017 May 2. pii: S0085-2538(17)30177-1. doi: 10.1016/j.kint.2017.03.005. [Epub ahead of print].

The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling

Authors:
Gong B, Shen W, Xiao W, Meng Y, Meng A, Jia S
Citation:
Elife. 2017 May 2;6. pii: e26362. doi: 10.7554/eLife.26362. [Epub ahead of print]
Epub:
Yes
Abstract:
The non-canonical Wnt/Ca2+ signaling pathway plays important roles in embryonic development, tissue formation and diseases....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gong B, Shen W, Xiao W, Meng Y, Meng A, Jia S. The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling. Elife. 2017 May 2;6. pii: e26362. doi: 10.7554/eLife.26362. [Epub ahead of print].

An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations

Authors:
Stayner C, Poole CA, McGlashan SR, Pilanthananond M, Brauning R, Markie D, Lett B, Slobbe L, Chae A, Johnstone AC, Jensen CG, McEwan JC, Dittmer K, Parker K, Wiles A, Blackburne W, Leichter A, Leask M, Pinnapureddy A, Jennings M, Horsfield JA, Walker RJ, Eccles MR
Citation:
Sci Rep. 2017;7:1601. doi:10.1038/s41598-017-01519-4
Epub:
Not Epub
Abstract:
Meckel syndrome (MKS) is an inherited autosomal recessive hepatorenal fibrocystic syndrome, caused by mutations in TMEM67,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stayner C, Poole CA, McGlashan SR, Pilanthananond M, Brauning R, Markie D, Lett B, Slobbe L, Chae A, Johnstone AC, Jensen CG, McEwan JC, Dittmer K, Parker K, Wiles A, Blackburne W, Leichter A, Leask M, Pinnapureddy A, Jennings M, Horsfield JA, Walker RJ, Eccles MR. An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations. Sci Rep. 2017;7:1601. doi:10.1038/s41598-017-01519-4.

Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling

Authors:
Rasouli SJ, Stainier DYR
Citation:
Nat Comm. 2017;8:15281 doi:10.1038/ncomms15281
Epub:
Not Epub
Abstract:
Trabeculation is crucial for cardiac muscle growth in vertebrates. This process requires the Erbb2/4 ligand Neuregulin (Nrg),...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rasouli SJ, Stainier DYR. Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling. Nat Comm. 2017;8:15281 doi:10.1038/ncomms15281.

The angiotensin II receptor type 1b is the primary sensor of intraluminal pressure in cerebral artery smooth muscle cells

Authors:
Pires PW, Ko E-A, Pritchard HAT, Rudokas M, Yamasaki E, Earley S
Citation:
J Physiol. 2017;[Epub ahead of print] doi:10.1113/JP274310
Epub:
Yes
Abstract:
Myogenic vasoconstriction, which reflects the intrinsic ability of smooth muscle cells to contract in response to increases in...
Organism or Cell Type:
cell culture
Citation Extract:
Pires PW, Ko E-A, Pritchard HAT, Rudokas M, Yamasaki E, Earley S. The angiotensin II receptor type 1b is the primary sensor of intraluminal pressure in cerebral artery smooth muscle cells. J Physiol. 2017;[Epub ahead of print] doi:10.1113/JP274310.

Augmented quantal release of acetylcholine at the vertebrate neuromuscular junction following tdp-43 depletion

Authors:
Dzieciolowska S, Drapeau P, Armstrong GAB
Citation:
PLoS One. 2017 May 4;12(5):e0177005. doi: 10.1371/journal.pone.0177005. eCollection 2017
Epub:
Not Epub
Abstract:
TAR DNA binding protein (TDP-43) is a 43 kD, predominately nuclear, protein involved in RNA metabolism. Of clinical...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dzieciolowska S, Drapeau P, Armstrong GAB. Augmented quantal release of acetylcholine at the vertebrate neuromuscular junction following tdp-43 depletion. PLoS One. 2017 May 4;12(5):e0177005. doi: 10.1371/journal.pone.0177005. eCollection 2017.

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