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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Endoderm Jagged induces liver and pancreas duct lineage in zebrafish
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Citation:
Nat Comm. 2017;8:769. doi:10.1038/s41467-017-00666-6 Epub:
Not Epub Abstract:
Liver duct paucity is characteristic of children born with Alagille Syndrome (ALGS), a disease associated with JAGGED1... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang D, Gates KP, Barske L, Wang G, Lancman JJ, Zeng X-XI, Groff M, Kasper Wang K, Parsons MJ, Crump JG, Dong PDS. Endoderm Jagged induces liver and pancreas duct lineage in zebrafish. Nat Comm. 2017;8:769. doi:10.1038/s41467-017-00666-6. |
U1 snRNP telescripting regulates a size-function-stratified human genome
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Citation:
Nat Struct Mol Biol. 2017 Oct 2. doi: 10.1038/nsmb.3473. [Epub ahead of print] Epub:
Yes Abstract:
U1 snRNP (U1) functions in splicing introns and telescripting, which suppresses premature cleavage and polyadenylation (PCPA).... Organism or Cell Type:
cell culture: HeLa Citation Extract: Oh JM, Di C, Venters CC, Guo J, Arai C, So BR, Pinto AM, Zhang Z, Wan L, Younis I, Dreyfuss G. U1 snRNP telescripting regulates a size-function-stratified human genome. Nat Struct Mol Biol. 2017 Oct 2. doi: 10.1038/nsmb.3473. [Epub ahead of print]. |
Construction of nanostructured DNA harbouring phosphorodiamidate morpholino oligonucleotide for controlled tissue distribution in mice
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Citation:
J Drug Target. 2017 Oct 3:1-34. doi: 10.1080/1061186X.2017.1387789. [Epub ahead of print] Epub:
Not Epub Abstract:
Phosphorodiamidate morpholino oligonucleotides (PMOs) are a class of antisense oligonucleotides used in the treatment of... Delivery Method:
i.v. injection Organism or Cell Type:
mice Citation Extract: Takahashi Y, Araie Y, Nomura D, Takahashi Y, Sano K, Saji H, Takakura Y, Nishikawa M. Construction of nanostructured DNA harbouring phosphorodiamidate morpholino oligonucleotide for controlled tissue distribution in mice. J Drug Target. 2017 Oct 3:1-34. doi: 10.1080/1061186X.2017.1387789. [Epub ahead of print]. |
PRAJA is overexpressed in glioblastoma and contributes to neural precursor development
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Citation:
Genes Cancer. 2017 Jul;8(7-8):640-649. doi: 10.18632/genesandcancer.151 Epub:
Not Epub Abstract:
PRAJA, a RING-H2 E3 ligase, is abundantly expressed in brain tissues such as the cerebellum and frontal cortex, amongst others... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shin J, Mishra V, Glasgow E, Zaidi S, Ohshiro K, Chitti B, Kapadia AA, Rana N, Mishra L, Deng CX, Rao S, Mishra B. PRAJA is overexpressed in glioblastoma and contributes to neural precursor development. Genes Cancer. 2017 Jul;8(7-8):640-649. doi: 10.18632/genesandcancer.151. |
Novel Mutation of LRP6 Identified in Chinese Han Population Links Canonical WNT Signaling to Neural Tube Defects
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Citation:
Birth Defects Res. 2017 Sep 29. doi: 10.1002/bdr2.1122. [Epub ahead of print] Epub:
Yes Abstract:
BACKGROUND: Neural tube defects (NTDs), the second most frequent cause of human congenital abnormalities, are debilitating... Organism or Cell Type:
zebrafish Citation Extract: Shi Z, Yang X, Li BB, Chen S, Yang L, Cheng L, Zhang T, Wang H, Zheng Y
. Novel Mutation of LRP6 Identified in Chinese Han Population Links Canonical WNT Signaling to Neural Tube Defects. Birth Defects Res. 2017 Sep 29. doi: 10.1002/bdr2.1122. [Epub ahead of print]. |
Six1 and Eya1 both promote and arrest neuronal differentiation by activating multiple Notch pathway genes
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Citation:
Dev Biol. 2017 Sep 22. pii: S0012-1606(17)30412-8. doi: 10.1016/j.ydbio.2017.09.027. [Epub ahead of print] Epub:
Yes Abstract:
The transcription factor Six1 and its cofactor Eya1 are important regulators of neurogenesis in cranial placodes, activating... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Riddiford N, Schlosser G. Six1 and Eya1 both promote and arrest neuronal differentiation by activating multiple Notch pathway genes. Dev Biol. 2017 Sep 22. pii: S0012-1606(17)30412-8. doi: 10.1016/j.ydbio.2017.09.027. [Epub ahead of print]. |
LDB2 regulates the expression of DLL4 through the formation of oligomeric complexes in endothelial cells
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Citation:
BMB Rep. 2017 Sep 26. pii: 3929. [Epub ahead of print] Epub:
Yes Abstract:
Delta-like ligand 4 (DLL4) expression in endothelial cells is intimately associated with angiogenic sprouting and vascular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Choi HJ, Rho SS, Choi DH, Kwon YG. LDB2 regulates the expression of DLL4 through the formation of oligomeric complexes in endothelial cells. BMB Rep. 2017 Sep 26. pii: 3929. [Epub ahead of print]. |
Thyroid hormone regulates hematopoiesis via the TR-KLF9 axis
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Citation:
Blood. 2017;[Epub ahead of print] doi:10.1182/blood-2017-05-783043 Epub:
Yes Abstract:
Congenital hypothyroidism (CH) is one of the most prevalent endocrine diseases and is often accompanied by anemia and... Organism or Cell Type:
zebrafish Citation Extract: Zhang Y, Xue Y, Cao C, Huang J, Hong Q, Hai T, Jia Q, Wang X, Qin G, Yao J, Wang X, Zheng Q, Zhang R, Li Y, Luo A, Zhang N, Shi Q, Wang Y, Ying H, Liu Z, Wang H, Meng A, Zhou Q, Wei H, Liu F, Zhao J. Thyroid hormone regulates hematopoiesis via the TR-KLF9 axis. Blood. 2017;[Epub ahead of print] doi:10.1182/blood-2017-05-783043. |
Interleukin 8 mediates bcl-xL-induced enhancement of human melanoma cell dissemination and angiogenesis in a zebrafish xenograft model
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Citation:
Int J Cancer. 2017;[Accepted Manuscript] doi10.1002/ijc.31075 Epub:
Yes Abstract:
The protein bcl-xL is able to enhance the secretion of the pro-inflammatory chemokine interleukin 8 (CXCL8) in human melanoma... Organism or Cell Type:
zebrafish Citation Extract: Gabellini C, Gómez-Abenza E, Ibáñez-Molero S, Tupone MG, Pérez-Oliva AB, de Oliveira S, Del Bufalo D, Mulero V. Interleukin 8 mediates bcl-xL-induced enhancement of human melanoma cell dissemination and angiogenesis in a zebrafish xenograft model. Int J Cancer. 2017;[Accepted Manuscript] doi10.1002/ijc.31075. |
Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I
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Citation:
Nat Comm. 2017;8:694. doi:10.1038/s41467-017-00774-3 Epub:
Not Epub Abstract:
A key feature of meiosis is the step-wise removal of cohesin, the protein complex holding sister chromatids together, first... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: El Yakoubi W, Buffin E, Cladière D, Gryaznova Y, Berengue I, Touati SA, Gómez R, Suja JA, van Deursen JM, Wassmann K. Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I. Nat Comm. 2017;8:694. doi:10.1038/s41467-017-00774-3. |