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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Neurotrophic effects of progranulin in vivo in reversing motor neuron defects caused by over or under expression of TDP-43 or FUS
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Citation:
PLoS One. 2017 Mar 30;12(3):e0174784. doi: 10.1371/journal.pone.0174784. eCollection 2017 Epub:
Not Epub Abstract:
Progranulin (PGRN) is a glycoprotein with multiple roles in normal and disease states. Mutations within the GRN gene cause... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chitramuthu BP, Kay DG, Bateman A, Bennett HP. Neurotrophic effects of progranulin in vivo in reversing motor neuron defects caused by over or under expression of TDP-43 or FUS. PLoS One. 2017 Mar 30;12(3):e0174784. doi: 10.1371/journal.pone.0174784. eCollection 2017. |
Correction: Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes
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Citation:
PLoS One. 2017 Apr 6;12(4):e0175608. doi: 10.1371/journal.pone.0175608. eCollection 2017 Epub:
Not Epub Abstract:
No abstract available. The correction provides missing Morpholino sequences. Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Place ES, Smith JC. Correction: Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes. PLoS One. 2017 Apr 6;12(4):e0175608. doi: 10.1371/journal.pone.0175608. eCollection 2017. |
Progranulin regulates neurogenesis in the developing vertebrate retina
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Citation:
Dev Neurobiol. 2017 Apr 5. doi: 10.1002/dneu.22499. [Epub ahead of print] Epub:
Not Epub Abstract:
We evaluated the expression and function of the microglia-specific growth factor, Progranulin-a (Pgrn-a) during developmental... Organism or Cell Type:
zebrafish Citation Extract: Walsh CE, Hitchcock PF. Progranulin regulates neurogenesis in the developing vertebrate retina. Dev Neurobiol. 2017 Apr 5. doi: 10.1002/dneu.22499. [Epub ahead of print]. |
Aipl1 is required for cone photoreceptor function and survival through the stability of Pde6c and Gc3 in zebrafish
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Citation:
Sci Rep. 2017 Apr 5;7:45962. doi: 10.1038/srep45962 Epub:
Not Epub Abstract:
Genetic mutations in aryl hydrocarbon receptor interacting protein-like 1 (AIPL1) cause photoreceptor degeneration associated... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Iribarne M, Nishiwaki Y, Nakamura S, Araragi M, Oguri E, Masai I. Aipl1 is required for cone photoreceptor function and survival through the stability of Pde6c and Gc3 in zebrafish. Sci Rep. 2017 Apr 5;7:45962. doi: 10.1038/srep45962. |
Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy
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Citation:
Proc Natl Acad Sci U S A. 2017 Apr 3. pii: 201613203. doi: 10.1073/pnas.1613203114. [Epub ahead of print] Epub:
Yes Abstract:
Duchenne muscular dystrophy (DMD) is a lethal genetic disorder caused by an absence of the dystrophin protein in bodywide... Delivery Method:
peptide-linked, bare oligo injection Organism or Cell Type:
Canis familiaris (dog) Citation Extract: Echigoya Y, Nakamura A, Nagata T, Urasawa N, Lim KR, Trieu N, Panesar D, Kuraoka M, Moulton HM, Saito T, Aoki Y, Iversen P, Sazani P, Kole R, Maruyama R, Partridge T, Takeda S, Yokota T. Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy. Proc Natl Acad Sci U S A. 2017 Apr 3. pii: 201613203. doi: 10.1073/pnas.1613203114. [Epub ahead of print]. |
Zebrafish Mecp2 is required for proper axonal elongation of motor neurons and synapse formation
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Citation:
Dev Neurobiol. 2017 Apr 2. doi: 10.1002/dneu.22498. [Epub ahead of print] Epub:
Yes Abstract:
Rett syndrome is a severe neurodevelopmental disorder. It is caused by a mutation in methyl-CpG binding protein 2 (MecP2), a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nozawa K, Lin Y, Kubodera R, Shimizu Y, Tanaka H, Ohshima T. Zebrafish Mecp2 is required for proper axonal elongation of motor neurons and synapse formation. Dev Neurobiol. 2017 Apr 2. doi: 10.1002/dneu.22498. [Epub ahead of print]. |
The Wilms tumor protein WT1 stimulates transcription of the gene encoding insulin-like growth factor binding protein 5 (IGFBP5)
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Citation:
Gene. 2017 Mar 30. pii: S0378-1119(17)30217-2. doi: 10.1016/j.gene.2017.03.037. [Epub ahead of print] Epub:
Yes Abstract:
Insulin-like growth factor (IGF) binding proteins (IGFBPs) constitute a family of six secreted proteins that regulate the... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mouse kidney explant Citation Extract: Müller M, Persson AB, Krueger K, Kirschner KM, Scholz H. The Wilms tumor protein WT1 stimulates transcription of the gene encoding insulin-like growth factor binding protein 5 (IGFBP5). Gene. 2017 Mar 30. pii: S0378-1119(17)30217-2. doi: 10.1016/j.gene.2017.03.037. [Epub ahead of print]. |
In Vivo Imaging of Transgenic Gene Expression in Individual Retinal Progenitors in Chimeric Zebrafish Embryos to Study Cell Nonautonomous Influences
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Citation:
J Vis Exp. 2017 Mar 22;(121). doi: 10.3791/55490 Epub:
Not Epub Abstract:
The genetic and technical strengths have made the zebrafish vertebrate a key model organism in which the consequences of gene... Link:
Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dudczig S, Currie PD, Poggi L, Jusuf PR. In Vivo Imaging of Transgenic Gene Expression in Individual Retinal Progenitors in Chimeric Zebrafish Embryos to Study Cell Nonautonomous Influences. J Vis Exp. 2017 Mar 22;(121). doi: 10.3791/55490. |
Tropomyosin 1: Multiple roles in the developing heart and in the formation of congenital heart defects
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Citation:
J Mol Cell Cardiol. 2017 Mar 27;106:1-13. doi: 10.1016/j.yjmcc.2017.03.006. [Epub ahead of print] Epub:
Not Epub Abstract:
Tropomyosin 1 (TPM1) is an essential sarcomeric component, stabilising the thin filament and facilitating actin's... Delivery Method:
pluronic gel Organism or Cell Type:
Gallus gallus (chick) Citation Extract: England J, Granados-Riveron J, Polo-Parada L, Kuriakose D, Moore C, Brook JD, Rutland CS, Setchfield K, Gell C, Ghosh TK, Bu'Lock F, Thornborough C, Ehler E, Loughna S. Tropomyosin 1: Multiple roles in the developing heart and in the formation of congenital heart defects. J Mol Cell Cardiol. 2017 Mar 27;106:1-13. doi: 10.1016/j.yjmcc.2017.03.006. [Epub ahead of print]. |
Wnt8a expands the pool of embryonic kidney progenitors in zebrafish
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Citation:
Dev Biol. 2017 Mar 27. pii: S0012-1606(16)30674-1. doi: 10.1016/j.ydbio.2017.03.027. [Epub ahead of print] Epub:
Yes Abstract:
During zebrafish embryogenesis the pronephric kidney arises from a small population of posterior mesoderm cells that then... Organism or Cell Type:
zebrafish Citation Extract: Naylor RW, Han HI, Hukriede NA, Davidson AJ. Wnt8a expands the pool of embryonic kidney progenitors in zebrafish. Dev Biol. 2017 Mar 27. pii: S0012-1606(16)30674-1. doi: 10.1016/j.ydbio.2017.03.027. [Epub ahead of print]. |