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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Making a Morpholino Experiment Work: Controls, Favoring Specificity, Improving Efficacy, Storage, and Dose

Authors:
Moulton JD
Citation:
Methods Mol Biol. 2017;1565:17-29. doi: 10.1007/978-1-4939-6817-6_2
Epub:
Not Epub
Abstract:
A good Morpholino experiment starts with oligos that have been carefully designed to minimize off-target RNA binding....
Link:
http://www.springer.com/us/book/9781493968152
Citation Extract:
Moulton JD. Making a Morpholino Experiment Work: Controls, Favoring Specificity, Improving Efficacy, Storage, and Dose. Methods Mol Biol. 2017;1565:17-29. doi: 10.1007/978-1-4939-6817-6_2.

Invention and Early History of Morpholinos: From Pipe Dream to Practical Products

Authors:
Summerton JE
Citation:
Methods Mol Biol. 2017;1565:1-15. doi: 10.1007/978-1-4939-6817-6_1
Epub:
Not Epub
Abstract:
Beginning with my concept in 1969 to treat disease at the nucleic acid level using antisense nucleic acids, antisense has...
Link:
http://www.springer.com/us/book/9781493968152
Citation Extract:
Summerton JE. Invention and Early History of Morpholinos: From Pipe Dream to Practical Products. Methods Mol Biol. 2017;1565:1-15. doi: 10.1007/978-1-4939-6817-6_1.

Aggregation and Disaggregation of Morpholino Oligomers in Solution

Authors:
Chow G, Morcos PA, Moulton HM
Citation:
Methods Mol Biol. 2017;1565:31-38. doi: 10.1007/978-1-4939-6817-6_3
Epub:
Not Epub
Abstract:
Morpholino oligomers are effective antisense molecules to regulate gene expression and the US FDA has approved a Morpholino...
Link:
http://www.springer.com/us/book/9781493968152
Citation Extract:
Chow G, Morcos PA, Moulton HM. Aggregation and Disaggregation of Morpholino Oligomers in Solution. Methods Mol Biol. 2017;1565:31-38. doi: 10.1007/978-1-4939-6817-6_3.

Germ line control of female sex determination in zebrafish

Authors:
Siegfried KR, Nüsslein-Volhard C
Citation:
Dev Biol. 2008 Dec 15;324(2):277-87. doi: 10.1016/j.ydbio.2008.09.025. Epub 2008 Oct 7
Epub:
Not Epub
Abstract:
A major transition during development of the gonad is commitment from an undifferentiated "bi-potential" state to...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160608012384
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Siegfried KR, Nüsslein-Volhard C. Germ line control of female sex determination in zebrafish. Dev Biol. 2008 Dec 15;324(2):277-87. doi: 10.1016/j.ydbio.2008.09.025. Epub 2008 Oct 7.

Mind Bomb-Binding Partner RanBP9 Plays a Contributory Role in Retinal Development

Authors:
Yoo K-W, Thiruvarangan M, Jeong Y-M, Lee M-S, Maddirevula S, Rhee M, Bae Y-K, Kim H-G, Kim C-H
Citation:
Mol Cells. 2017;40(4):[Epub ahead of print] doi:molcells.2017.2308
Epub:
Yes
Abstract:
Ran-binding protein family member, RanBP9 has been reported in various basic cellular mechanisms and neuropathological...
Link:
http://www.molcells.org/journal/view.html?doi=10.14348/molcells.2017.2308&
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yoo K-W, Thiruvarangan M, Jeong Y-M, Lee M-S, Maddirevula S, Rhee M, Bae Y-K, Kim H-G, Kim C-H. Mind Bomb-Binding Partner RanBP9 Plays a Contributory Role in Retinal Development. Mol Cells. 2017;40(4):[Epub ahead of print] doi:molcells.2017.2308.

AMPA glutamate receptors are required for sensory-organ formation and morphogenesis in the basal chordate

Authors:
Hirai S, Hotta K, Kubo Y, Nishino A, Okabe S, Okamura Y, Okado H
Citation:
Proc Natl Acad Sci U S A. 2017;[Epub ahead of print] doi:10.1073/pnas.1612943114
Epub:
Yes
Abstract:
AMPA-type glutamate receptors (GluAs) mediate fast excitatory transmission in the vertebrate central nervous system (CNS), and...
Link:
http://www.pnas.org/content/early/2017/03/21/1612943114.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis (ascidian)
Citation Extract:
Hirai S, Hotta K, Kubo Y, Nishino A, Okabe S, Okamura Y, Okado H. AMPA glutamate receptors are required for sensory-organ formation and morphogenesis in the basal chordate. Proc Natl Acad Sci U S A. 2017;[Epub ahead of print] doi:10.1073/pnas.1612943114.

Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance

Authors:
Nakajima H, Yamamoto K, Agarwala S, Terai K, Fukui H, Fukuhara S, Ando K, Miyazaki T, Yokota Y, Schmelzer E, Belting H-G, Affolter M, Lecaudey V, Mochizuki N
Citation:
Dev Cell. 2017;40:523-36. doi:10.1016/j.devcel.2017.02.019
Epub:
Not Epub
Abstract:
Endothelial cells (ECs) line the inside of blood vessels and respond to mechanical cues generated by blood flow. Mechanical...
Link:
http://www.cell.com/developmental-cell/fulltext/S1534-5807(17)30115-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nakajima H, Yamamoto K, Agarwala S, Terai K, Fukui H, Fukuhara S, Ando K, Miyazaki T, Yokota Y, Schmelzer E, Belting H-G, Affolter M, Lecaudey V, Mochizuki N. Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance. Dev Cell. 2017;40:523-36. doi:10.1016/j.devcel.2017.02.019.

MicroRNAs Establish Uniform Traits during the Architecture of Vertebrate Embryos

Authors:
Kasper DM, Moro A, Ristori E, Narayanan A, Hill-Teran G, Fleming E, Moreno-Mateos M, Vejnar CE, Zhang J, Lee D, Gu M, Gerstein M, Giraldez A, Nicoli S
Citation:
Dev Cell. 2017;40(6):552-565.e5. doi:10.1016/j.devcel.2017.02.021
Epub:
Not Epub
Abstract:
Proper functioning of an organism requires cells and tissues to behave in uniform, well-organized ways. How this optimum of...
Link:
http://www.cell.com/developmental-cell/pdf/S1534-5807(17)30117-X.pdf
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kasper DM, Moro A, Ristori E, Narayanan A, Hill-Teran G, Fleming E, Moreno-Mateos M, Vejnar CE, Zhang J, Lee D, Gu M, Gerstein M, Giraldez A, Nicoli S. MicroRNAs Establish Uniform Traits during the Architecture of Vertebrate Embryos. Dev Cell. 2017;40(6):552-565.e5. doi:10.1016/j.devcel.2017.02.021.

Fatty acid binding protein 11a is required for brain vessel integrity in zebrafish

Authors:
Zhang J, Qi J, Wu S, Peng L, Shi Y, Yang J, Yin Z, Gao Y, Wang C, Gong J, Zhang H, Zhang J, Liu D
Citation:
Front Physiol. 2017 Apr 11;8:214. doi: 10.3389/fphys.2017.00214. eCollection 2017.
Epub:
Not Epub
Abstract:
The monolayer of endothelial cells lining the intima of all blood vessel wall forms a semipermeable barrier that regulates...
Link:
http://journal.frontiersin.org/article/10.3389/fphys.2017.00214/abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang J, Qi J, Wu S, Peng L, Shi Y, Yang J, Yin Z, Gao Y, Wang C, Gong J, Zhang H, Zhang J, Liu D. Fatty acid binding protein 11a is required for brain vessel integrity in zebrafish. Front Physiol. 2017 Apr 11;8:214. doi: 10.3389/fphys.2017.00214. eCollection 2017..

Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis

Authors:
Ding Y, Ploper D, Sosa EA, Colozza G, Moriyama Y, Benitez MDJ, Zhang K, Merkurjev D, De Robertis EM
Citation:
Proc Natl Acad Sci U S A. 2017;[Epub ahead of print] doi:10.1073/pnas.1700766114
Epub:
Yes
Abstract:
The earliest event in Xenopus development is the dorsal accumulation of nuclear β-catenin under the influence of cytoplasmic...
Link:
http://www.pnas.org/content/early/2017/03/22/1700766114.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ding Y, Ploper D, Sosa EA, Colozza G, Moriyama Y, Benitez MDJ, Zhang K, Merkurjev D, De Robertis EM. Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis. Proc Natl Acad Sci U S A. 2017;[Epub ahead of print] doi:10.1073/pnas.1700766114.

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