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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Plastin-3 extends survival and reduces severity in mouse models of spinal muscular atrophy
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Citation:
JCI Insight. 2017 Mar 9;2(5):e89970. doi: 10.1172/jci.insight.89970 Epub:
Not Epub Abstract:
Spinal muscular atrophy (SMA) is a leading genetic cause of infantile death and is caused by the loss of survival motor neuron-... Delivery Method:
intracerebroventricular injection Organism or Cell Type:
mouse Citation Extract: Kaifer KA, Villalón E, Osman EY, Glascock JJ, Arnold LL, Cornelison DD, Lorson CL. Plastin-3 extends survival and reduces severity in mouse models of spinal muscular atrophy. JCI Insight. 2017 Mar 9;2(5):e89970. doi: 10.1172/jci.insight.89970. |
Neurotransmitter-Regulated Regeneration in the Zebrafish Retina
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Citation:
Stem Cell Reports. 2017 Mar 6. pii: S2213-6711(17)30074-7. doi: 10.1016/j.stemcr.2017.02.007. [Epub ahead of print] Epub:
Yes Abstract:
Current efforts to repair damaged or diseased mammalian retinas are inefficient and largely incapable of fully restoring vision... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rao MB, Didiano D, Patton JG. Neurotransmitter-Regulated Regeneration in the Zebrafish Retina. Stem Cell Reports. 2017 Mar 6. pii: S2213-6711(17)30074-7. doi: 10.1016/j.stemcr.2017.02.007. [Epub ahead of print]. |
Pth4, an ancient parathyroid hormone lost in eutherian mammals, reveals a new brain-to-bone signaling pathway
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Citation:
FASEB J. 2017 Feb;31(2):569-583. doi: 10.1096/fj.201600815R Epub:
Not Epub Abstract:
Regulation of bone development, growth, and remodeling traditionally has been thought to depend on endocrine and autocrine/... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Suarez-Bregua P, Torres-Nuñez E, Saxena A, Guerreiro P, Braasch I, Prober DA, Moran P, Cerda-Reverter JM, Du SJ, Adrio F, Power DM, Canario AV, Postlethwait JH, Bronner ME, Cañestro C, Rotllant J. Pth4, an ancient parathyroid hormone lost in eutherian mammals, reveals a new brain-to-bone signaling pathway. FASEB J. 2017 Feb;31(2):569-583. doi: 10.1096/fj.201600815R. |
Mutations in γ-secretase subunit-encoding PSENEN underlie Dowling-Degos disease associated with acne inversa
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Citation:
J Clin Invest. 2017 Mar 13. pii: 90667. doi: 10.1172/JCI90667. [Epub ahead of print] Epub:
Yes Abstract:
Dowling-Degos disease (DDD) is an autosomal-dominant disorder of skin pigmentation associated with mutations in keratin 5 (KRT5... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ralser DJ, Basmanav FB, Tafazzoli A, Wititsuwannakul J, Delker S, Danda S, Thiele H, Wolf S, Busch M, Pulimood SA, Altmüller J, Nürnberg P, Lacombe D, Hillen U, Wenzel J, Frank J, Odermatt B, Betz RC. Mutations in γ-secretase subunit-encoding PSENEN underlie Dowling-Degos disease associated with acne inversa. J Clin Invest. 2017 Mar 13. pii: 90667. doi: 10.1172/JCI90667. [Epub ahead of print]. |
Functional differences between Tcf1 isoforms in early Xenopus development
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Citation:
Int J Dev Biol. 2017;61(1-2):29-34. doi: 10.1387/ijdb.160308od Epub:
Not Epub Abstract:
In Xenopus gastrula stage embryos, four isoforms of Tcf1 (B, C, D and E) are present with high amino acid sequence conservation... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Roël G, Van Den Broek O, Destrée O. Functional differences between Tcf1 isoforms in early Xenopus development. Int J Dev Biol. 2017;61(1-2):29-34. doi: 10.1387/ijdb.160308od. |
Molecular mechanisms regulating ocular apoptosis in zebrafish gdf6a mutants
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Citation:
Invest Ophthalmol Vis Sci. 2013 Aug 28;54(8):5871-9. doi: 10.1167/iovs.12-11315 Epub:
Not Epub Abstract:
Purpose.: To characterize the molecular mechanisms underlying retinal apoptosis induced by loss of Gdf6, a TGFβ ligand.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pant SD, March LD, Famulski JK, French CR, Lehmann OJ, Waskiewicz AJ. Molecular mechanisms regulating ocular apoptosis in zebrafish gdf6a mutants. Invest Ophthalmol Vis Sci. 2013 Aug 28;54(8):5871-9. doi: 10.1167/iovs.12-11315. |
Churchill regulates cell movement and mesoderm specification by repressing Nodal signaling
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Citation:
BMC Dev Biol. 2007 Nov 2;7:120 Epub:
Not Epub Abstract:
BACKGROUND: Cell movements are essential to the determination of cell fates during development. The zinc-finger transcription... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Londin ER, Mentzer L, Sirotkin HI. Churchill regulates cell movement and mesoderm specification by repressing Nodal signaling. BMC Dev Biol. 2007 Nov 2;7:120. |
A splicing mutation in VPS4B causes dentin dysplasia I
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Citation:
J Med Genet. 2016 Sep;53(9):624-33. doi: 10.1136/jmedgenet-2015-103619 Epub:
Not Epub Abstract:
BACKGROUND: Dentin dysplasia I (DDI) is a genetically heterogeneous autosomal-dominant disorder characterised by rootless teeth... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang Q, Chen D, Xiong F, Chen D, Liu C, Liu Y, Yu Q, Xiong J, Liu J, Li K, Zhao L, Ye Y, Zhou H, Hu L, Tian Z, Shang X, Zhang L, Wei X, Zhou W, Li D, Zhang W, Xu X
. A splicing mutation in VPS4B causes dentin dysplasia I. J Med Genet. 2016 Sep;53(9):624-33. doi: 10.1136/jmedgenet-2015-103619. |
GATA5 SUMOylation is indispensable for zebrafish cardiac development
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Citation:
Biochim Biophys Acta. 2017 Mar 8. pii: S0304-4165(17)30088-0. doi: 10.1016/j.bbagen.2017.03.005. [Epub ahead of print] Epub:
Yes Abstract:
BACKGROUND: SUMOylation is a critical regulatory protein modification in eukaryotic cells and plays a pivotal role in cardiac... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wen B, Yuan H, Liu X, Wang H, Chen S, Chen Z, de The H, Zhou J, Zhu J. GATA5 SUMOylation is indispensable for zebrafish cardiac development. Biochim Biophys Acta. 2017 Mar 8. pii: S0304-4165(17)30088-0. doi: 10.1016/j.bbagen.2017.03.005. [Epub ahead of print]. |
Whole exome sequencing coupled with unbiased functional analysis reveals new Hirschsprung disease genes
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Citation:
Genome Biol. 2017 Mar 8;18(1):48. doi: 10.1186/s13059-017-1174-6 Epub:
Not Epub Abstract:
BACKGROUND: Hirschsprung disease (HSCR), which is congenital obstruction of the bowel, results from a failure of enteric... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gui H, Schriemer D, Cheng WW, Chauhan RK, Antiňolo G, Berrios C, Bleda M, Brooks AS, Brouwer RW, Burns AJ, Cherny SS, Dopazo J, Eggen BJ, Griseri P, Jalloh B, Le TL, Lui VC, Luzón-Toro B, Matera I, Ngan ES, Pelet A, Ruiz-Ferrer M, Sham PC, Shepherd IT, So MT, Sribudiani Y, Tang CS, van den Hout MC, van der Linde HC, van Ham TJ, van IJcken WF, Verheij JB, Amiel J, Borrego S, Ceccherini I, Chakravarti A, Lyonnet S, Tam PK, Garcia-Barceló MM, Hofstra RM. Whole exome sequencing coupled with unbiased functional analysis reveals new Hirschsprung disease genes. Genome Biol. 2017 Mar 8;18(1):48. doi: 10.1186/s13059-017-1174-6. |