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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Cos2/Kif7 and OSM-3/Kif17 Regulate Onset of Outer Segment Development in Zebrafish Photoreceptors Through Distinct Mechanisms

Authors:
Lewis TR, Kundinger SR, Pavlovich AL, Bostrom JR, Link BA, Besharse JC
Citation:
Dev Biol. 2017 Mar 21. pii: S0012-1606(17)30126-4. doi: 10.1016/j.ydbio.2017.03.019. [Epub ahead of print]
Epub:
Yes
Abstract:
Zebrafish morphants of osm-3/kif17, a kinesin-2 family member and intraflagellar transport motor, have photoreceptor outer...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160617301264
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lewis TR, Kundinger SR, Pavlovich AL, Bostrom JR, Link BA, Besharse JC. Cos2/Kif7 and OSM-3/Kif17 Regulate Onset of Outer Segment Development in Zebrafish Photoreceptors Through Distinct Mechanisms. Dev Biol. 2017 Mar 21. pii: S0012-1606(17)30126-4. doi: 10.1016/j.ydbio.2017.03.019. [Epub ahead of print].

La-related protein 6 controls ciliated cell differentiation

Authors:
Manojlovic Z, Earwood R, Kato A, Perez D, Cabrera OA, Didier R, Megraw TL, Stefanovic B, Kato Y
Citation:
Cilia. 2017 Mar 23;6:4. doi: 10.1186/s13630-017-0047-7. eCollection 2017 Mar 23
Epub:
Not Epub
Abstract:
BACKGROUND: La-related protein 6 (LARP6) is an evolutionally conserved RNA-binding protein. Vertebrate LARP6 binds the 5'...
Link:
https://ciliajournal.biomedcentral.com/articles/10.1186/s13630-017-0047-7
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Manojlovic Z, Earwood R, Kato A, Perez D, Cabrera OA, Didier R, Megraw TL, Stefanovic B, Kato Y. La-related protein 6 controls ciliated cell differentiation. Cilia. 2017 Mar 23;6:4. doi: 10.1186/s13630-017-0047-7. eCollection 2017 Mar 23.

The chemokine receptor CXCR4 promotes granuloma formation by sustaining a mycobacteria-induced angiogenesis programme

Authors:
Torraca V, Tulotta C, Snaar-Jagalska BE, Meijer AH
Citation:
Sci Rep. 2017 Mar 23;7:45061. doi: 10.1038/srep45061
Epub:
Not Epub
Abstract:
CXC chemokine receptor 4 plays a critical role in chemotaxis and leukocyte differentiation. Furthermore, there is increasing...
Link:
http://www.nature.com/articles/srep45061
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Torraca V, Tulotta C, Snaar-Jagalska BE, Meijer AH. The chemokine receptor CXCR4 promotes granuloma formation by sustaining a mycobacteria-induced angiogenesis programme. Sci Rep. 2017 Mar 23;7:45061. doi: 10.1038/srep45061.

Chordin and dickkopf-1b are essential for the formation of head structures through activation of the FGF signaling pathway in zebrafish

Authors:
Tanaka S, Hosokawa H, Weinberg ES, Maegawa S
Citation:
Dev Biol. 2017 Mar 1. pii: S0012-1606(16)30469-9. doi: 10.1016/j.ydbio.2017.02.018. [Epub ahead of print]
Epub:
Yes
Abstract:
The ability of the Spemann organizer to induce dorsal axis formation is dependent on downstream factors of the maternal Wnt/β-...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616304699
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tanaka S, Hosokawa H, Weinberg ES, Maegawa S. Chordin and dickkopf-1b are essential for the formation of head structures through activation of the FGF signaling pathway in zebrafish. Dev Biol. 2017 Mar 1. pii: S0012-1606(16)30469-9. doi: 10.1016/j.ydbio.2017.02.018. [Epub ahead of print].

Inhibition of serum and glucocorticoid regulated kinase-1 as novel therapy for cardiac arrhythmia disorders

Authors:
Bezzerides VJ, Zhang A, Xiao L, Simonson B, Khedkar SA, Baba S, Ottaviano F, Lynch S, Hessler K, Rigby AC, Milan D, Das S, Rosenzweig A
Citation:
Sci Rep. 2017;7:346. doi:10.1038/s41598-017-00413-3
Epub:
Not Epub
Abstract:
Alterations in sodium flux (INa) play an important role in the pathogenesis of cardiac arrhythmias and may also contribute to...
Link:
http://www.nature.com/articles/s41598-017-00413-3
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bezzerides VJ, Zhang A, Xiao L, Simonson B, Khedkar SA, Baba S, Ottaviano F, Lynch S, Hessler K, Rigby AC, Milan D, Das S, Rosenzweig A. Inhibition of serum and glucocorticoid regulated kinase-1 as novel therapy for cardiac arrhythmia disorders. Sci Rep. 2017;7:346. doi:10.1038/s41598-017-00413-3.

Systemic Antisense Therapeutics for Dystrophin and Myostatin Exon Splice Modulation Improve Muscle Pathology of Adult mdx Mice

Authors:
Lu-Nguyen N, Malerba A, Popplewell L, Schnell F, Hanson G, Dickson G
Citation:
Mol Ther Nucleic Acids. 2017 Mar 17;6:15-28. doi: 10.1016/j.omtn.2016.11.009
Epub:
Not Epub
Abstract:
Antisense-mediated exon skipping is a promising approach for the treatment of Duchenne muscular dystrophy (DMD), a rare life-...
Link:
http://www.cell.com/molecular-therapy-family/nucleic-acids/abstract/S2162-2531(16)30367-5
Delivery Method:
peptide-linked
Organism or Cell Type:
mouse mdx
Citation Extract:
Lu-Nguyen N, Malerba A, Popplewell L, Schnell F, Hanson G, Dickson G. Systemic Antisense Therapeutics for Dystrophin and Myostatin Exon Splice Modulation Improve Muscle Pathology of Adult mdx Mice. Mol Ther Nucleic Acids. 2017 Mar 17;6:15-28. doi: 10.1016/j.omtn.2016.11.009.

Molecular physiology of the hypocalcemic action of fibroblast growth factor 23 in zebrafish (Danio rerio)

Authors:
Lin CH, Hu HJ, Hwang PP
Citation:
Endocrinology. 2017 Mar 1. doi: 10.1210/en.2016-1883. [Epub ahead of print]
Epub:
Yes
Abstract:
Fibroblast growth factor 23 (FGF23), a hormone required for phosphorus metabolism, was recently proposed to act on Ca2+ uptake...
Link:
https://academic.oup.com/endo/article-abstract/doi/10.1210/en.2016-1883/3058743/Molecular-physiology-of-the-hypocalcemic-action-of
Organism or Cell Type:
zebrafish
Citation Extract:
Lin CH, Hu HJ, Hwang PP. Molecular physiology of the hypocalcemic action of fibroblast growth factor 23 in zebrafish (Danio rerio). Endocrinology. 2017 Mar 1. doi: 10.1210/en.2016-1883. [Epub ahead of print].

sall1 and sall4 repress pou5f3 family expression to allow neural patterning, differentiation, and morphogenesis in Xenopus laevis

Authors:
Exner CR, Kim AY, Mardjuki SM, Harland RM
Citation:
Dev Biol. 2017 Mar 18. pii: S0012-1606(16)30754-0. doi: 10.1016/j.ydbio.2017.03.015. [Epub ahead of print]
Epub:
Yes
Abstract:
The embryonic precursor of the vertebrate central nervous system, the neural plate, is patterned along the anterior-posterior...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616307540
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Exner CR, Kim AY, Mardjuki SM, Harland RM. sall1 and sall4 repress pou5f3 family expression to allow neural patterning, differentiation, and morphogenesis in Xenopus laevis. Dev Biol. 2017 Mar 18. pii: S0012-1606(16)30754-0. doi: 10.1016/j.ydbio.2017.03.015. [Epub ahead of print].

Discovery of Novel Determinants of Endothelial Lineage using Chimeric Heterokaryons

Authors:
Wong WT, Matrone G, Tian XY, Tomoiaga SA, Au KF, Meng S, Yamazoe S, Sieveking D, Chen K, Burns DM, Chen JK, Blau HM, Cooke JP
Citation:
eLife. 2017; doi:10.7554/eLife.23588
Epub:
Not Epub
Abstract:
We wish to identify determinants of endothelial lineage. Murine embryonic stem cells (mESC) were fused with human endothelial...
Link:
https://elifesciences.org/content/6/e23588
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wong WT, Matrone G, Tian XY, Tomoiaga SA, Au KF, Meng S, Yamazoe S, Sieveking D, Chen K, Burns DM, Chen JK, Blau HM, Cooke JP. Discovery of Novel Determinants of Endothelial Lineage using Chimeric Heterokaryons. eLife. 2017; doi:10.7554/eLife.23588.

Actomyosin-generated tension on cadherin is similar between dividing and non-dividing epithelial cells in early Xenopus laevis embryos

Authors:
Herbomel G, Hatte G, Roul J, Padilla-Parra S, Tassan J-P, Tramier M
Citation:
Sci Rep. 2017;7:45058 doi:10.1038/srep45058
Epub:
Not Epub
Abstract:
Epithelia represent a unique situation where polarized cells must maintain sufficiently strong cell-cell contacts to guarantee...
Link:
http://www.nature.com/articles/srep45058
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Herbomel G, Hatte G, Roul J, Padilla-Parra S, Tassan J-P, Tramier M. Actomyosin-generated tension on cadherin is similar between dividing and non-dividing epithelial cells in early Xenopus laevis embryos. Sci Rep. 2017;7:45058 doi:10.1038/srep45058.

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