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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration

Authors:
Ohki Y, Wenninger-Weinzierl A, Hruscha A, Asakawa K, Kawakami K, Haass C, Edbauer D, Schmid B
Citation:
Mol Neurodegener. 2017 Jan 14;12(1):6. doi:10.1186/s13024-016-0146-8
Epub:
Not Epub
Abstract:
BACKGROUND: The most frequent genetic cause of frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ohki Y, Wenninger-Weinzierl A, Hruscha A, Asakawa K, Kawakami K, Haass C, Edbauer D, Schmid B. Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration. Mol Neurodegener. 2017 Jan 14;12(1):6. doi:10.1186/s13024-016-0146-8.

The neuronal transcription factor NPAS4 is a strong inducer of sprouting angiogenesis and tip cell formation

Authors:
Esser JS, Charlet A, Schmidt M, Heck S, Allen A, Lother A, Epting D, Patterson C, Bode C, Moser M
Citation:
Cardiovasc Res. 2017 Jan 12. pii: cvw248. doi: 10.1093/cvr/cvw248. [Epub ahead of print]
Epub:
Yes
Abstract:
RATIONALE: Regarding branching morphogenesis, neurogenesis and angiogenesis share common principle mechanisms and make use of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Esser JS, Charlet A, Schmidt M, Heck S, Allen A, Lother A, Epting D, Patterson C, Bode C, Moser M. The neuronal transcription factor NPAS4 is a strong inducer of sprouting angiogenesis and tip cell formation. Cardiovasc Res. 2017 Jan 12. pii: cvw248. doi: 10.1093/cvr/cvw248. [Epub ahead of print].

Ftr82 Is Critical for Vascular Patterning during Zebrafish Development

Authors:
Chang H-W, Wang W-D, Chiu C-C, Chen C-H, Wang Y-S, Chen Z-Y, Liu W, Tai M-H, Wen Z-H, Wu C-Y
Citation:
Int J Mol Sci. 2017;18(1):156. doi:10.3390/ijms18010156
Epub:
Not Epub
Abstract:
Cellular components and signaling pathways are required for the proper growth of blood vessels. Here, we report for the first...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chang H-W, Wang W-D, Chiu C-C, Chen C-H, Wang Y-S, Chen Z-Y, Liu W, Tai M-H, Wen Z-H, Wu C-Y. Ftr82 Is Critical for Vascular Patterning during Zebrafish Development. Int J Mol Sci. 2017;18(1):156. doi:10.3390/ijms18010156.

Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis

Authors:
Macia MS, Halbritter J, Delous M, Bredrup C, Gutter A, Filhol E, Mellgren AEC, Leh S, Bizet A, Braun DA, Gee HY, Silbermann F, Henry C, Krug P, Bole-Feysot C, Nitschké P, Joly D, Nicoud P, Paget A, Haugland H, Brackmann D, Ahmet N, Sandford R, Cengiz N, Knappskog PM, Boman H, Linghu B, Yang F, Oakeley EJ, Mézard SP, Sailer AW, Johansson S, Rødah E, Saunier S, Hildebrandt F, Benmerah A
Citation:
Am J Hum Genet. 2017;[Epub ahead of print] doi:10.1016/j.ajhg.2016.12.011
Epub:
Yes
Abstract:
Nephronophthisis (NPH), an autosomal-recessive tubulointerstitial nephritis, is the most common cause of hereditary end-stage...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Macia MS, Halbritter J, Delous M, Bredrup C, Gutter A, Filhol E, Mellgren AEC, Leh S, Bizet A, Braun DA, Gee HY, Silbermann F, Henry C, Krug P, Bole-Feysot C, Nitschké P, Joly D, Nicoud P, Paget A, Haugland H, Brackmann D, Ahmet N, Sandford R, Cengiz N, Knappskog PM, Boman H, Linghu B, Yang F, Oakeley EJ, Mézard SP, Sailer AW, Johansson S, Rødah E, Saunier S, Hildebrandt F, Benmerah A. Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis. Am J Hum Genet. 2017;[Epub ahead of print] doi:10.1016/j.ajhg.2016.12.011.

Centriolin, a centriole-appendage protein, regulates peripheral spindle migration and asymmetric division in mouse meiotic oocytes

Authors:
Sun TY, Wang HY, Kwon JW, Yuan B, Lee IW, Cui XS, Kim NH
Citation:
Cell Cycle. 2017 Jan 11:0. doi: 10.1080/15384101.2016.1264544. [Epub ahead of print]
Epub:
Yes
Abstract:
Unlike somatic cells mitosis, germ cell meiosis consists of two consecutive rounds of division that segregate homologous...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Sun TY, Wang HY, Kwon JW, Yuan B, Lee IW, Cui XS, Kim NH. Centriolin, a centriole-appendage protein, regulates peripheral spindle migration and asymmetric division in mouse meiotic oocytes. Cell Cycle. 2017 Jan 11:0. doi: 10.1080/15384101.2016.1264544. [Epub ahead of print].

Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing

Authors:
Zhang Y, O’Leary MN, Peri S, Wang M, Zha J, Melov S, Kappes DJ, Feng Q, Rhodes J, Amieux PS, Morris DR, Kennedy BK, Wiest DL
Citation:
Cell Rep. 2017;18:545-556. doi:10.1016/j.celrep.2016.12.034
Epub:
Not Epub
Abstract:
Most ribosomal proteins (RP) are regarded as essential, static components that contribute only to ribosome biogenesis and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Y, O’Leary MN, Peri S, Wang M, Zha J, Melov S, Kappes DJ, Feng Q, Rhodes J, Amieux PS, Morris DR, Kennedy BK, Wiest DL. Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing. Cell Rep. 2017;18:545-556. doi:10.1016/j.celrep.2016.12.034.

SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome

Authors:
Shaw ND, Brand H, Kupchinsky ZA, Bengani H, Plummer L, Jones TI, Erdin S, Williamson KA, Rainger J, Stortchevoi A, Samocha K, Currall BB, Dunican DS, Collins RL, Willer JR, Lek A, Lek M, Nassan M, Pereira S, Kammin T, Lucente D, Silva A, Seabra CM, Chiang C, An Y, Ansari M, Rainger JK, Joss S, Smith JC, <authors removed - database limit>, Schimmenti LA, Brasseur B, Cesaretti C, García-Ortiz JE, Buitrago TP, Silva OP, Hoffman JD, Mühlbauer W, Ruprecht KW, Loeys BL, Shino M, Kaindl AM, Cho CH, Morton CC, Meehan RR, van Heyningen V, Liao EC, Balasubramanian R, Hall JE, Seminara SB, Macarthur D, Moore SA, Yoshiura KI, Gusella JF, Marsh JA, Graham JM Jr, Lin AE, Katsanis N, Jones PL, Crowley WF Jr, Davis EE, FitzPatrick DR, Talkowski ME
Citation:
Nat Genet. 2017 Jan 9. doi: 10.1038/ng.3743. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Arhinia, or absence of the nose, is a rare malformation of unknown etiology that is often accompanied by ocular and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shaw ND, Brand H, Kupchinsky ZA, Bengani H, Plummer L, Jones TI, Erdin S, Williamson KA, Rainger J, Stortchevoi A, Samocha K, Currall BB, Dunican DS, Collins RL, Willer JR, Lek A, Lek M, Nassan M, Pereira S, Kammin T, Lucente D, Silva A, Seabra CM, Chiang C, An Y, Ansari M, Rainger JK, Joss S, Smith JC, <authors removed - database limit>, Schimmenti LA, Brasseur B, Cesaretti C, García-Ortiz JE, Buitrago TP, Silva OP, Hoffman JD, Mühlbauer W, Ruprecht KW, Loeys BL, Shino M, Kaindl AM, Cho CH, Morton CC, Meehan RR, van Heyningen V, Liao EC, Balasubramanian R, Hall JE, Seminara SB, Macarthur D, Moore SA, Yoshiura KI, Gusella JF, Marsh JA, Graham JM Jr, Lin AE, Katsanis N, Jones PL, Crowley WF Jr, Davis EE, FitzPatrick DR, Talkowski ME. SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome. Nat Genet. 2017 Jan 9. doi: 10.1038/ng.3743. [Epub ahead of print].

Neuronal sFlt1 and Vegfaa determine venous sprouting and spinal cord vascularization

Authors:
Wild R, Klems A, Takamiya M0, Hayashi Y, Strähle U, Ando K, Mochizuki N, van Impel A, Schulte-Merker S, Krueger J, Preau L, le Noble F
Citation:
Nat Comm. 2017;8:13991. doi:10.1038/ncomms13991
Epub:
Not Epub
Abstract:
Formation of organ-specific vasculatures requires cross-talk between developing tissue and specialized endothelial cells. Here...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wild R, Klems A, Takamiya M0, Hayashi Y, Strähle U, Ando K, Mochizuki N, van Impel A, Schulte-Merker S, Krueger J, Preau L, le Noble F. Neuronal sFlt1 and Vegfaa determine venous sprouting and spinal cord vascularization. Nat Comm. 2017;8:13991. doi:10.1038/ncomms13991.

The larvicide pyriproxyfen blamed during the Zika virus outbreak does not cause microcephaly in zebrafish embryos

Authors:
Dzieciolowska S, Larroque AL, Kranjec EA, Drapeau P, Samarut E
Citation:
Sci Rep. 2017 Jan 4;7:40067. doi: 10.1038/srep40067
Epub:
Not Epub
Abstract:
Although the zika virus (ZIKV) has now been strongly correlated with emerging cases of microcephaly in the Americas, suspicions...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dzieciolowska S, Larroque AL, Kranjec EA, Drapeau P, Samarut E. The larvicide pyriproxyfen blamed during the Zika virus outbreak does not cause microcephaly in zebrafish embryos. Sci Rep. 2017 Jan 4;7:40067. doi: 10.1038/srep40067.

Endoplasmic reticulum chaperone Gp96 controls actomyosin dynamics and protects against pore-forming toxins

Authors:
Mesquita FS, Brito C, Mazon Moya MJ, Pinheiro JC, Mostowy S, Cabanes D, Sousa S
Citation:
EMBO Rep. 2016 Dec 30. pii: e201642833. doi: 10.15252/embr.201642833. [Epub ahead of print]
Epub:
Yes
Abstract:
During infection, plasma membrane (PM) blebs protect host cells against bacterial pore-forming toxins (PFTs), but were also...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mesquita FS, Brito C, Mazon Moya MJ, Pinheiro JC, Mostowy S, Cabanes D, Sousa S. Endoplasmic reticulum chaperone Gp96 controls actomyosin dynamics and protects against pore-forming toxins. EMBO Rep. 2016 Dec 30. pii: e201642833. doi: 10.15252/embr.201642833. [Epub ahead of print].

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