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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Ndrg1b and fam49ab modulate the PTEN pathway to control T-cell lymphopoiesis in the zebrafish

Authors:
Li RA, Traver D, Matthes T, Bertrand JY
Citation:
Blood. 2016 Dec 29;128(26):3052-3060. doi: 10.1182/blood-2016-09-742502
Epub:
Not Epub
Abstract:
During hematopoiesis, the balance between proliferation, differentiation, and apoptosis is tightly regulated in order to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li RA, Traver D, Matthes T, Bertrand JY. Ndrg1b and fam49ab modulate the PTEN pathway to control T-cell lymphopoiesis in the zebrafish. Blood. 2016 Dec 29;128(26):3052-3060. doi: 10.1182/blood-2016-09-742502.

Purinergic P2Y Receptors Are Involved in Xenopus Head Formation

Authors:
Harata A, Nishida H, Nishihara A, Hashimoto C
Citation:
CellBio. 2016;5(4):49-65. doi:10.4236/cellbio.2016.54004
Epub:
Not Epub
Abstract:
P2Y receptors belong to the family of G protein-coupled receptors and are activated by nucleotides in the extracellular space....
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Harata A, Nishida H, Nishihara A, Hashimoto C. Purinergic P2Y Receptors Are Involved in Xenopus Head Formation. CellBio. 2016;5(4):49-65. doi:10.4236/cellbio.2016.54004.

Makorin-2 is a neurogenesis inhibitor downstream of phosphatidylinositol 3-kinase/Akt (PI3K/Akt) signal

Authors:
Yang PH, Cheung WK, Peng Y, He ML, Wu GQ, Xie D, Jiang BH, Huang QH, Chen Z, Lin MC, Kung HF
Citation:
J Biol Chem. 2008 Mar 28;283(13):8486-95. doi: 10.1074/jbc.M704768200
Epub:
Not Epub
Abstract:
Makorin-2 belongs to the makorin RING zinc finger gene family, which encodes putative ribonucleoproteins. Here we cloned the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Yang PH, Cheung WK, Peng Y, He ML, Wu GQ, Xie D, Jiang BH, Huang QH, Chen Z, Lin MC, Kung HF. Makorin-2 is a neurogenesis inhibitor downstream of phosphatidylinositol 3-kinase/Akt (PI3K/Akt) signal. J Biol Chem. 2008 Mar 28;283(13):8486-95. doi: 10.1074/jbc.M704768200.

The presence of Anf/Hesx1 homeobox gene in lampreys suggests that it could play an important role in emergence of telencephalon

Authors:
Bayramov AV, Ermakova GV, Eroshkin FM, Kucheryavyy AV, Martynova NY, Zaraisky AG
Citation:
Sci Rep. 2016 Dec 23;6:39849. doi: 10.1038/srep39849
Epub:
Not Epub
Abstract:
Accumulated evidence indicates that the core genetic mechanisms regulating early patterning of the brain rudiment in...
Delivery Method:
microinjection
Organism or Cell Type:
Lampetra fluviatilis (lamprey), Xenopus laevis
Citation Extract:
Bayramov AV, Ermakova GV, Eroshkin FM, Kucheryavyy AV, Martynova NY, Zaraisky AG. The presence of Anf/Hesx1 homeobox gene in lampreys suggests that it could play an important role in emergence of telencephalon. Sci Rep. 2016 Dec 23;6:39849. doi: 10.1038/srep39849.

Lens defects in Astyanax mexicanus Cavefish: evolution of crystallins and a role for alphaA-crystallin

Authors:
Hinaux H, Blin M, Fumey J, Legendre L, Heuzé A, Casane D, Rétaux S
Citation:
Dev Neurobiol. 2015 May;75(5):505-21. doi: 10.1002/dneu.22239
Epub:
Not Epub
Abstract:
The fish Astyanax mexicanus presents, within the same species, populations of river-dwelling surface fish (SF) and blind cave-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hinaux H, Blin M, Fumey J, Legendre L, Heuzé A, Casane D, Rétaux S. Lens defects in Astyanax mexicanus Cavefish: evolution of crystallins and a role for alphaA-crystallin. Dev Neurobiol. 2015 May;75(5):505-21. doi: 10.1002/dneu.22239.

Congenital myopathy results from misregulation of a muscle Ca2+ channel by mutant Stac3

Authors:
Linsley JW, Hsu IU, Groom L, Yarotskyy V, Lavorato M, Horstick EJ, Linsley D, Wang W, Franzini-Armstrong C, Dirksen RT, Kuwada JY
Citation:
Proc Natl Acad Sci U S A. 2016 Dec 21. pii: 201619238. doi: 10.1073/pnas.1619238114. [Epub ahead of print]
Epub:
Yes
Abstract:
Skeletal muscle contractions are initiated by an increase in Ca2+ released during excitation-contraction (EC) coupling, and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Linsley JW, Hsu IU, Groom L, Yarotskyy V, Lavorato M, Horstick EJ, Linsley D, Wang W, Franzini-Armstrong C, Dirksen RT, Kuwada JY. Congenital myopathy results from misregulation of a muscle Ca2+ channel by mutant Stac3. Proc Natl Acad Sci U S A. 2016 Dec 21. pii: 201619238. doi: 10.1073/pnas.1619238114. [Epub ahead of print].

The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation

Authors:
Mahale S, Kumar M, Sharma A, Babu A, Ranjan S, Sachidanandan C, Mylavarapu SV
Citation:
Sci Rep. 2016 Dec;6(1):22. doi: 10.1038/s41598-016-0030-3
Epub:
Not Epub
Abstract:
Cytoplasmic dynein 1 is a multi-protein intracellular motor essential for mediating several mitotic functions, including the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mahale S, Kumar M, Sharma A, Babu A, Ranjan S, Sachidanandan C, Mylavarapu SV. The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation. Sci Rep. 2016 Dec;6(1):22. doi: 10.1038/s41598-016-0030-3.

HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels

Authors:
Holland P, Knævelsrud H, Søreng K, Mathai BJ, Lystad AH, Pankiv S, Bjørndal GT, Schultz SW, Lobert VH, Chan RB, Zhou B, Liestøl K, Carlsson SR, Melia TJ, Di Paolo G, Simonsen A
Citation:
Nat Commun. 2016 Dec 22;7:13889. doi: 10.1038/ncomms13889
Epub:
Not Epub
Abstract:
A fundamental question is how autophagosome formation is regulated. Here we show that the PX domain protein HS1BP3 is a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Holland P, Knævelsrud H, Søreng K, Mathai BJ, Lystad AH, Pankiv S, Bjørndal GT, Schultz SW, Lobert VH, Chan RB, Zhou B, Liestøl K, Carlsson SR, Melia TJ, Di Paolo G, Simonsen A. HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels. Nat Commun. 2016 Dec 22;7:13889. doi: 10.1038/ncomms13889.

Transcriptome Profiling Identifies Ribosome Biogenesis as a Target of Alcohol Teratogenicity and Vulnerability during Early Embryogenesis

Authors:
Berres ME, Garic A, Flentke GR, Smith SM
Citation:
PLoS ONE. 2017;12(1):e0169351. doi:10.1371/journal.pone.0169351
Epub:
Not Epub
Abstract:
Fetal alcohol spectrum disorder (FASD) is a leading cause of neurodevelopmental disability. Individuals with FASD may exhibit a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Berres ME, Garic A, Flentke GR, Smith SM. Transcriptome Profiling Identifies Ribosome Biogenesis as a Target of Alcohol Teratogenicity and Vulnerability during Early Embryogenesis. PLoS ONE. 2017;12(1):e0169351. doi:10.1371/journal.pone.0169351.

Transient Inhibition of Endogenous Transforming Growth Factor- β1 (TGFβ1) in Hematopoietic Stem Cells Accelerates Engraftment and Enhances Multi-Lineage Repopulating Efficiency

Authors:
Bartelmez S, Storey C, Iversen P, Ruscetti F
Citation:
J Stem Cell Res Ther. 2016;1(7):00045. doi:10.15406/jsrt.2016.01.00045
Epub:
Not Epub
Abstract:
We show that ex vivo transient inhibition of endogenous transforming growth factor-β1 (TGFβ1) in highly enriched and partially...
Organism or Cell Type:
mouse with ex-vivo-treatment & return: Long Term Repopulating-Hematopoietic Stem Cells
Citation Extract:
Bartelmez S, Storey C, Iversen P, Ruscetti F. Transient Inhibition of Endogenous Transforming Growth Factor- β1 (TGFβ1) in Hematopoietic Stem Cells Accelerates Engraftment and Enhances Multi-Lineage Repopulating Efficiency. J Stem Cell Res Ther. 2016;1(7):00045. doi:10.15406/jsrt.2016.01.00045.

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