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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Neural Crest Migration and Survival Are Susceptible to Morpholino-Induced Artifacts

Authors:
Boer EF, Jette CA, Stewart RA
Citation:
PLoS One. 2016 Dec 22;11(12):e0167278. doi: 10.1371/journal.pone.0167278
Epub:
Not Epub
Abstract:
The neural crest (NC) is a stem cell-like embryonic population that is essential for generating and patterning the vertebrate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boer EF, Jette CA, Stewart RA. Neural Crest Migration and Survival Are Susceptible to Morpholino-Induced Artifacts. PLoS One. 2016 Dec 22;11(12):e0167278. doi: 10.1371/journal.pone.0167278.

Peptide-conjugated phosphorodiamidate morpholino oligomer (PPMO) restores carbapenem susceptibility to NDM-1-positive pathogens in vitro and in vivo

Authors:
Sully EK, Geller BL, Li L, Moody CM, Bailey SM, Moore AL, Wong M, Nordmann P, Daly SM, Sturge CR, Greenberg DE
Citation:
J Antimicrob Chemother. 2016 Dec 20. pii: dkw476. doi: 10.1093/jac/dkw476. [Epub ahead of print]
Epub:
Yes
Abstract:
OBJECTIVES: The objective of this study was to test the efficacy of an inhibitor of the New Delhi metallo-β- lactamase (NDM-1...
Delivery Method:
peptide-linked
Organism or Cell Type:
Escherichia coli
Citation Extract:
Sully EK, Geller BL, Li L, Moody CM, Bailey SM, Moore AL, Wong M, Nordmann P, Daly SM, Sturge CR, Greenberg DE. Peptide-conjugated phosphorodiamidate morpholino oligomer (PPMO) restores carbapenem susceptibility to NDM-1-positive pathogens in vitro and in vivo. J Antimicrob Chemother. 2016 Dec 20. pii: dkw476. doi: 10.1093/jac/dkw476. [Epub ahead of print].

CenpH regulates meiotic G2/M transition by modulating the APC/CCdh1-cyclin B1 pathway in oocytes

Authors:
Zhang T, Zhou Y, Li L, Wang ZB, Shen W, Schatten H, Sun QY
Citation:
Development. 2016 Dec 19. pii: dev.141135. [Epub ahead of print]
Epub:
Yes
Abstract:
Meiotic resumption (G2/M transition) and progression through meiosis I (MI) are two critical stages for producing fertilization...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Zhang T, Zhou Y, Li L, Wang ZB, Shen W, Schatten H, Sun QY. CenpH regulates meiotic G2/M transition by modulating the APC/CCdh1-cyclin B1 pathway in oocytes. Development. 2016 Dec 19. pii: dev.141135. [Epub ahead of print].

Sema3d controls collective endothelial cell migration by distinct mechanisms via Nrp1 and PlxnD1

Authors:
Hamm MJ, Kirchmaier BC, Herzog W
Citation:
J Cell Biol. 2016 Nov 7;215(3):415-430
Epub:
Not Epub
Abstract:
During cardiovascular development, tight spatiotemporal regulation of molecular cues is essential for controlling endothelial...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hamm MJ, Kirchmaier BC, Herzog W. Sema3d controls collective endothelial cell migration by distinct mechanisms via Nrp1 and PlxnD1. J Cell Biol. 2016 Nov 7;215(3):415-430.

Regulator of G protein signaling 2 (Rgs2) regulates neural crest development through Pparδ-Sox10 cascade

Authors:
Lin SJ, Chiang MC, Shih HY, Hsu LS, Yeh TH, Huang YC, Lin CY, Cheng YC
Citation:
Biochim Biophys Acta. 2016 Dec 12. pii: S0167-4889(16)30338-X. doi: 10.1016/j.bbamcr.2016.12.013. [Epub ahead of print]
Epub:
Yes
Abstract:
Neural crest cells are multipotent progenitors that migrate extensively and differentiate into numerous derivatives. The...
Organism or Cell Type:
zebrafish
Citation Extract:
Lin SJ, Chiang MC, Shih HY, Hsu LS, Yeh TH, Huang YC, Lin CY, Cheng YC. Regulator of G protein signaling 2 (Rgs2) regulates neural crest development through Pparδ-Sox10 cascade. Biochim Biophys Acta. 2016 Dec 12. pii: S0167-4889(16)30338-X. doi: 10.1016/j.bbamcr.2016.12.013. [Epub ahead of print].

Angiopoietin 2 signaling plays a critical role in neural crest cell migration

Authors:
McKinney MC, McLennan R, Kulesa PM
Citation:
BMC Biology. 2016;14:111 doi:10.1186/s12915-016-0323-9
Epub:
Not Epub
Abstract:
Background: Collective neural crest cell migration is critical to the form and function of the vertebrate face and neck,...
Delivery Method:
injection then electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
McKinney MC, McLennan R, Kulesa PM. Angiopoietin 2 signaling plays a critical role in neural crest cell migration. BMC Biology. 2016;14:111 doi:10.1186/s12915-016-0323-9.

Hermes regulates axon sorting in the optic tract by post-transcriptional regulation of Neuropilin 1

Authors:
Hörnberg H, Cioni J-M, Harris WA, Holt CE
Citation:
J Neurosci. 2016;36(50):12697-706. doi:10.1523/JNEUROSCI.2400-16.2016
Epub:
Not Epub
Abstract:
The establishment of precise topographic maps during neural development is facilitated by the pre-sorting of axons in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish and Xenopus laevis
Citation Extract:
Hörnberg H, Cioni J-M, Harris WA, Holt CE. Hermes regulates axon sorting in the optic tract by post-transcriptional regulation of Neuropilin 1. J Neurosci. 2016;36(50):12697-706. doi:10.1523/JNEUROSCI.2400-16.2016.

Planar cell polarity genes Frizzled3a, Vangl2, and Scribble are required for spinal commissural axon guidance

Authors:
Sun SD, Purdy AM, Walsh GS
Citation:
BMC Neurosci. 2016 Dec 12;17(1):83
Epub:
Not Epub
Abstract:
BACKGROUND: A fundamental feature of early nervous system development is the guidance of axonal projections to their targets in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun SD, Purdy AM, Walsh GS. Planar cell polarity genes Frizzled3a, Vangl2, and Scribble are required for spinal commissural axon guidance. BMC Neurosci. 2016 Dec 12;17(1):83.

Distinct molecular signature of murine fetal liver and adult hematopoietic stem cells identifies novel regulators of hematopoietic stem cell function

Authors:
Manesia JK, Franch M, Tabas-Madrid D, Nogales-Cadenas R, Vanwelden T, Van Den Bosch E, Xu Z, Pascual-Montano A, Khurana S, Verfaillie C
Citation:
Stem Cells Dev. 2016 Dec 13. [Epub ahead of print]
Epub:
Yes
Abstract:
During ontogeny, fetal liver (FL) acts as a major site for hematopoietic stem cell (HSC) maturation and expansion, while HSCs...
Organism or Cell Type:
zebrafish
Citation Extract:
Manesia JK, Franch M, Tabas-Madrid D, Nogales-Cadenas R, Vanwelden T, Van Den Bosch E, Xu Z, Pascual-Montano A, Khurana S, Verfaillie C. Distinct molecular signature of murine fetal liver and adult hematopoietic stem cells identifies novel regulators of hematopoietic stem cell function. Stem Cells Dev. 2016 Dec 13. [Epub ahead of print].

TGF-β Sensu Stricto Signaling Regulates Skeletal Morphogenesis in the Sea Urchin Embryo

Authors:
Sun Z, Ettensohn CA
Citation:
Dev Biol. 2016 Dec 9. pii: S0012-1606(16)30541-3. doi: 10.1016/j.ydbio.2016.12.007. [Epub ahead of print]
Epub:
Yes
Abstract:
Cell-cell signaling plays a prominent role in the formation of the embryonic skeleton of sea urchins, but the mechanisms are...
Organism or Cell Type:
Strongylocentrotus purpuratus and Lytechinus variegatus (sea urchin)
Citation Extract:
Sun Z, Ettensohn CA. TGF-β Sensu Stricto Signaling Regulates Skeletal Morphogenesis in the Sea Urchin Embryo. Dev Biol. 2016 Dec 9. pii: S0012-1606(16)30541-3. doi: 10.1016/j.ydbio.2016.12.007. [Epub ahead of print].

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