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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Loss of ZNF32 augments the regeneration of nervous lateral line system through negative regulation of SOX2 transcription

Authors:
Wei Y, Li K, Yao S, Gao J, Li J, Shang Y, Zhang J, Zhang L, Li Y, Mo X, Meng W, Xiang R, Hu J, Lin P, Wei Y
Citation:
Oncotarget. 2016 Sep 8. doi: 10.18632/oncotarget.11895. [Epub ahead of print]
Epub:
Yes
Abstract:
Human zinc finger protein 32 (ZNF32) is a Cys2-His2 zinc-finger transcription factor that plays an important role in cell fate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wei Y, Li K, Yao S, Gao J, Li J, Shang Y, Zhang J, Zhang L, Li Y, Mo X, Meng W, Xiang R, Hu J, Lin P, Wei Y. Loss of ZNF32 augments the regeneration of nervous lateral line system through negative regulation of SOX2 transcription. Oncotarget. 2016 Sep 8. doi: 10.18632/oncotarget.11895. [Epub ahead of print].

Preparation of Cell Lysate from Mouse Oocytes for Western Blotting Analysis

Authors:
Marangos P
Citation:
Methods Mol Biol. 2016;1457:209-15. doi: 10.1007/978-1-4939-3795-0_15
Epub:
Not Epub
Abstract:
Western Blotting has been used extensively for the identification of the protein factors that regulate mammalian oocyte meiosis...
Organism or Cell Type:
mouse oocyte
Citation Extract:
Marangos P. Preparation of Cell Lysate from Mouse Oocytes for Western Blotting Analysis. Methods Mol Biol. 2016;1457:209-15. doi: 10.1007/978-1-4939-3795-0_15.

The E3 ubiquitin ligase Hace1 is required for early embryonic development in Xenopus laevis

Authors:
Iimura A, Yamazaki F, Suzuki T, Endo T, Nishida E, Kusakabe M
Citation:
BMC Dev Biol. 2016;16:31. doi:10.1186/s12861-016-0132-y
Epub:
Not Epub
Abstract:
Background: HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (HACE1) regulates a wide variety of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Iimura A, Yamazaki F, Suzuki T, Endo T, Nishida E, Kusakabe M. The E3 ubiquitin ligase Hace1 is required for early embryonic development in Xenopus laevis. BMC Dev Biol. 2016;16:31. doi:10.1186/s12861-016-0132-y.

Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair

Authors:
Middel V, Zhou L, Takamiya M, Beil T, Shahid M, Roostalu U, Grabher C, Rastegar S, Reischl M, Nienhaus GU, Strähle U
Citation:
Nat Commun. 2016 Sep 19;7:12875. doi: 10.1038/ncomms12875
Epub:
Not Epub
Abstract:
Failure to repair the sarcolemma leads to muscle cell death, depletion of stem cells and myopathy. Hence, membrane lesions are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Middel V, Zhou L, Takamiya M, Beil T, Shahid M, Roostalu U, Grabher C, Rastegar S, Reischl M, Nienhaus GU, Strähle U. Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair. Nat Commun. 2016 Sep 19;7:12875. doi: 10.1038/ncomms12875.

Mechanosensing is critical for axon growth in the developing brain

Authors:
Koser DE, Thompson AJ, Foster SK, Dwivedy A, Pillai EK, Sheridan GK, Svoboda H, Viana M, Costa LD, Guck J, Holt CE, Franze K
Citation:
Nat Neurosci. 2016 Sep 19. doi: 10.1038/nn.4394. [Epub ahead of print]
Epub:
Yes
Abstract:
During nervous system development, neurons extend axons along well-defined pathways. The current understanding of axon...
Organism or Cell Type:
Xenopus
Citation Extract:
Koser DE, Thompson AJ, Foster SK, Dwivedy A, Pillai EK, Sheridan GK, Svoboda H, Viana M, Costa LD, Guck J, Holt CE, Franze K. Mechanosensing is critical for axon growth in the developing brain. Nat Neurosci. 2016 Sep 19. doi: 10.1038/nn.4394. [Epub ahead of print].

Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis

Authors:
Walentek P, Quigley IK, Sun DI, Sajjan UK, Kintner C, Harland RM
Citation:
Elife. 2016 Sep 13;5. pii: e17557. doi: 10.7554/eLife.17557. [Epub ahead of print]
Epub:
Yes
Abstract:
Upon cell cycle exit, centriole-to-basal body transition facilitates cilia formation. The centriolar protein Cp110 is a...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Walentek P, Quigley IK, Sun DI, Sajjan UK, Kintner C, Harland RM. Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis. Elife. 2016 Sep 13;5. pii: e17557. doi: 10.7554/eLife.17557. [Epub ahead of print].

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition

Authors:
Dahl JA, Jung I, Aanes H, Greggains GD, Manaf A, Lerdrup M, Li G, Kuan S, Li B, Lee AY, Preissl S, Jermstad I, Haugen MH, Suganthan R, Bjørås M, Hansen K, Dalen KT, Fedorcsak P, Ren B, Klungland A
Citation:
Nature. 2016 Sep 14. doi: 10.1038/nature19360. [Epub ahead of print]
Epub:
Yes
Abstract:
Maternal-to-zygotic transition (MZT) is essential for the formation of a new individual, but is still poorly understood despite...
Organism or Cell Type:
mouse oocyte
Citation Extract:
Dahl JA, Jung I, Aanes H, Greggains GD, Manaf A, Lerdrup M, Li G, Kuan S, Li B, Lee AY, Preissl S, Jermstad I, Haugen MH, Suganthan R, Bjørås M, Hansen K, Dalen KT, Fedorcsak P, Ren B, Klungland A. Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition. Nature. 2016 Sep 14. doi: 10.1038/nature19360. [Epub ahead of print].

Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy

Authors:
Ayhan DH, Tamer YT, Akbar M, Bailey SM, Wong M, Daly SM, Greenberg DE, Toprak E
Citation:
PLoS Biol. 2016 Sep 15;14(9):e1002552. doi: 10.1371/journal.pbio.1002552. eCollection 2016 Sep
Epub:
Not Epub
Abstract:
The lack of effective and well-tolerated therapies against antibiotic-resistant bacteria is a global public health problem...
Delivery Method:
Peptide-linked
Organism or Cell Type:
cell culture: Escherichia coli, Klebsiella pneumoniae, Salmonella enterica, Acinetobacter baumannii, Pseudomonas aeruginosa, Burkholderia cenocepacia
Citation Extract:
Ayhan DH, Tamer YT, Akbar M, Bailey SM, Wong M, Daly SM, Greenberg DE, Toprak E. Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy. PLoS Biol. 2016 Sep 15;14(9):e1002552. doi: 10.1371/journal.pbio.1002552. eCollection 2016 Sep.

From Cryptic Toward Canonical Pre-mRNA Splicing in Pompe Disease: a Pipeline for the Development of Antisense Oligonucleotides

Authors:
Bergsma AJ, In 't Groen SL, Verheijen FW, van der Ploeg AT, Pijnappel WP
Citation:
Mol Ther Nucleic Acids. 2016 Sep 13;5(9):e361. doi: 10.1038/mtna.2016.75
Epub:
Not Epub
Abstract:
While 9% of human pathogenic variants have an established effect on pre-mRNA splicing, it is suspected that an additional 20%...
Organism or Cell Type:
human primary fibroblasts
Citation Extract:
Bergsma AJ, In 't Groen SL, Verheijen FW, van der Ploeg AT, Pijnappel WP. From Cryptic Toward Canonical Pre-mRNA Splicing in Pompe Disease: a Pipeline for the Development of Antisense Oligonucleotides. Mol Ther Nucleic Acids. 2016 Sep 13;5(9):e361. doi: 10.1038/mtna.2016.75.

NSrp70 is significant for embryonic growth and development, being a crucial factor for gastrulation and mesoderm induction

Authors:
Lee SH, Kim C, Lee HK, Kim YK, Ismail T, Jeong Y, Park K, Park MJ, Park DS, Lee HS
Citation:
Biochem Biophys Res Commun. 2016 Sep 13. pii: S0006-291X(16)31502-9. doi: 10.1016/j.bbrc.2016.09.051. [Epub ahead of print]
Epub:
Yes
Abstract:
NSrp70 (nuclear speckle-related protein 70), a recently discovered protein and it belongs to the serine/arginine (SR) rich...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Lee SH, Kim C, Lee HK, Kim YK, Ismail T, Jeong Y, Park K, Park MJ, Park DS, Lee HS. NSrp70 is significant for embryonic growth and development, being a crucial factor for gastrulation and mesoderm induction. Biochem Biophys Res Commun. 2016 Sep 13. pii: S0006-291X(16)31502-9. doi: 10.1016/j.bbrc.2016.09.051. [Epub ahead of print].

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