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Solid-phase-supported synthesis of morpholino-glycine oligonucleotide mimics.

Authors: 
Abramova TV, Belov SS, Tarasenko YV, Silnikov VN
Citation: 
Beilstein J Org Chem. 2014;10:1151-8. doi:10.3762/bjoc.10.115
Abstract: 
Efficient solid phase supported peptide synthesis (SPPS) of morpholino glycine oligonucleotide (MorGLy) mimics has been developed. The proposed strategy includes a novel specially designed labile linker group containing the oxalyl residue and the 2-aminomethylmorpholino nucleoside analogues as first subunits.
Epub: 
Not Epub