You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Histone H3K27 acetylation precedes active transcription during zebrafish zygotic genome activation as revealed by live-cell analysis

Authors:
Sato Y, Hilbert L, Oda H, Wan Y, Heddleston JM, Chew TL, Zaburdaev V, Keller P, Lionnet T, Vastenhouw N, Kimura H
Citation:
Development. 2019 Sep 30;146(19). pii: dev179127. doi: 10.1242/dev.179127
Epub:
Not Epub
Abstract:
Histone post-translational modifications are key gene expression regulators, but their rapid dynamics during development remain...
Link:
https://dev.biologists.org/content/146/19/dev179127.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sato Y, Hilbert L, Oda H, Wan Y, Heddleston JM, Chew TL, Zaburdaev V, Keller P, Lionnet T, Vastenhouw N, Kimura H. Histone H3K27 acetylation precedes active transcription during zebrafish zygotic genome activation as revealed by live-cell analysis. Development. 2019 Sep 30;146(19). pii: dev179127. doi: 10.1242/dev.179127.

NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress

Authors:
Han D, Schomacher L, Schüle KM, Mallick M, Musheev MU, Karaulanov E, Krebs L, von Seggern A, Niehrs C
Citation:
eLife. 2019;8:e49044. doi:10.7554/eLife.49044
Epub:
Not Epub
Abstract:
Base excision repair (BER) functions not only in the maintenance of genomic integrity but also in active DNA demethylation and...
Link:
https://elifesciences.org/articles/49044
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Han D, Schomacher L, Schüle KM, Mallick M, Musheev MU, Karaulanov E, Krebs L, von Seggern A, Niehrs C. NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress. eLife. 2019;8:e49044. doi:10.7554/eLife.49044.

Defective excitatory/inhibitory synaptic balance and increased neuron apoptosis in a zebrafish model of Dravet syndrome

Authors:
Brenet A, Hassan-Abdi R, Somkhit J, Yanicostas C, Soussi-Yanicostas N
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/781393
Epub:
Not Epub
Abstract:
Dravet syndrome is a type of severe childhood epilepsy that responds poorly to current anti-epileptic drugs. In recent years,...
Link:
https://www.biorxiv.org/content/biorxiv/early/2019/09/28/781393.full.pdf
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brenet A, Hassan-Abdi R, Somkhit J, Yanicostas C, Soussi-Yanicostas N. Defective excitatory/inhibitory synaptic balance and increased neuron apoptosis in a zebrafish model of Dravet syndrome. bioRxiv. 2019;[preprint] doi:10.1101/781393.

Preservation of zebrafish genetic resources through testis cryopreservation and spermatogonia transplantation

Authors:
Marinović Z, Li Q, Lujić J, Iwasaki Y, Csenki Z, Urbányi B, Yoshizaki G, Horváth Á
Citation:
Sci Rep. 2019;9(1):13681. doi:10.1038/s41598-019-50169-1
Epub:
Not Epub
Abstract:
Zebrafish is one of the most commonly used model organisms in biomedical, developmental and genetic research. The production of...
Link:
https://www.nature.com/articles/s41598-019-50169-1
Citation Extract:
Marinović Z, Li Q, Lujić J, Iwasaki Y, Csenki Z, Urbányi B, Yoshizaki G, Horváth Á. Preservation of zebrafish genetic resources through testis cryopreservation and spermatogonia transplantation. Sci Rep. 2019;9(1):13681. doi:10.1038/s41598-019-50169-1.

Characterization of biklf/klf17-deficient zebrafish in posterior lateral line neuromast and hatching gland development

Authors:
Suzuki H, Ishizaka T, Yanagi K, Sone R, Sunaga Y, Ohga R, Kawahara A
Citation:
Sci Rep. 2019;9(1):13680. doi:10.1038/s41598-019-50149-5
Epub:
Not Epub
Abstract:
Krüpple-like factors (Klfs) are highly conserved zinc-finger transcription factors that regulate various developmental...
Link:
https://www.nature.com/articles/s41598-019-50149-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Suzuki H, Ishizaka T, Yanagi K, Sone R, Sunaga Y, Ohga R, Kawahara A. Characterization of biklf/klf17-deficient zebrafish in posterior lateral line neuromast and hatching gland development. Sci Rep. 2019;9(1):13680. doi:10.1038/s41598-019-50149-5.

Broadening and Enhancing Functions of Antibody by Self-Assembling Multimerization at Cell Surface

Authors:
Li L, Wang J, Li Y, Radford DC, Yang J, Kopecek J
Citation:
ACS Nano. 2019 Sep 25. doi: 10.1021/acsnano.9b04868. [Epub ahead of print]
Epub:
Yes
Abstract:
Monoclonal antibody therapy has offered treatment benefits. Nonetheless, lack of efficacy still exists, partially because...
Link:
https://pubs.acs.org/doi/10.1021/acsnano.9b04868
Organism or Cell Type:
mice
Citation Extract:
Li L, Wang J, Li Y, Radford DC, Yang J, Kopecek J. Broadening and Enhancing Functions of Antibody by Self-Assembling Multimerization at Cell Surface. ACS Nano. 2019 Sep 25. doi: 10.1021/acsnano.9b04868. [Epub ahead of print].

Reverse Genetic Approaches to Investigate the Neurobiology of the Cnidarian Sea Anemone Nematostella vectensis

Authors:
Havrilak JA, Layden MJ
Citation:
Methods Mol Biol. 2020;2047:25-43. doi: 10.1007/978-1-4939-9732-9_2
Epub:
Not Epub
Abstract:
The cnidarian sea anemone Nematostella vectensis has grown in popularity as a model system to complement the ongoing work in...
Link:
https://link.springer.com/protocol/10.1007%2F978-1-4939-9732-9_2
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Havrilak JA, Layden MJ. Reverse Genetic Approaches to Investigate the Neurobiology of the Cnidarian Sea Anemone Nematostella vectensis. Methods Mol Biol. 2020;2047:25-43. doi: 10.1007/978-1-4939-9732-9_2.

Towards the identification of causal genes for age-related macular degeneration

Authors:
Cheng F-F, Zhuang Y-Y, Wen X-R, Xue A, Yang J, Jin Z-B
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/778613
Epub:
Not Epub
Abstract:
Age-related macular degeneration (AMD) is a leading cause of visual impairment in ageing populations and has no radical...
Link:
https://www.biorxiv.org/content/10.1101/778613v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cheng F-F, Zhuang Y-Y, Wen X-R, Xue A, Yang J, Jin Z-B. Towards the identification of causal genes for age-related macular degeneration. bioRxiv. 2019;[preprint] doi:10.1101/778613 .

Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog/Gli Is Required for Tracheoesophageal Separation

Authors:
Nasr T, Mancini P, Rankin SA, Edwards NA, Agricola ZN, Kenny AP, Kinney JL, Daniels K, Vardanyan J, Han L, SL, Cha S-W, Wells JM, Kofron MJ, Zorn AM
Citation:
bioRxiv. 2019[preprint] doi:10.1101/777664
Epub:
Not Epub
Abstract:
The trachea and esophagus arise from the separation of a common foregut tube during early fetal development. Mutations in key...
Link:
https://www.biorxiv.org/content/10.1101/777664v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Nasr T, Mancini P, Rankin SA, Edwards NA, Agricola ZN, Kenny AP, Kinney JL, Daniels K, Vardanyan J, Han L, SL, Cha S-W, Wells JM, Kofron MJ, Zorn AM. Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog/Gli Is Required for Tracheoesophageal Separation. bioRxiv. 2019[preprint] doi:10.1101/777664 .

ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia

Authors:
Haas M, Vázquez JLG, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P
Citation:
Cell Rep. 2019;[Epub ahead of print] doi:10.1016/j.celrep.2019.08.063
Epub:
Yes
Abstract:
Mucociliary epithelia provide a first line of defense against pathogens. Impaired regeneration and remodeling of mucociliary...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(19)31118-0
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Haas M, Vázquez JLG, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P. ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia. Cell Rep. 2019;[Epub ahead of print] doi:10.1016/j.celrep.2019.08.063.

Pages