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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Possible cooption of a VEGF-driven tubulogenesis program for biomineralization in echinoderms

Authors:
Morgulis M, Gildor T, Roopin M, Sher N, Malik A, Lalzar M, Dines M, Ben-Tabou de-Leon S, Khalaily L, Ben-Tabou de-Leon S
Citation:
Proc Natl Acad Sci USA. 2019;[Epub aheasd of print] doi:10.1073/pnas.1902126116
Epub:
Yes
Abstract:
Biomineralization is the process by which living organisms use minerals to form hard structures that protect and support them....
Link:
https://www.pnas.org/content/early/2019/05/30/1902126116
Delivery Method:
microinjection
Organism or Cell Type:
Paracentrotus lividus (sea urchin)
Citation Extract:
Morgulis M, Gildor T, Roopin M, Sher N, Malik A, Lalzar M, Dines M, Ben-Tabou de-Leon S, Khalaily L, Ben-Tabou de-Leon S. Possible cooption of a VEGF-driven tubulogenesis program for biomineralization in echinoderms. Proc Natl Acad Sci USA. 2019;[Epub aheasd of print] doi:10.1073/pnas.1902126116.

Cytochrome P450 26A1 modulates uterine dendritic cells in mice early pregnancy

Authors:
Gu AQ, Li DD, Wei DP, Liu YQ, Ji WH, Yang Y, Lin HY, Peng JP
Citation:
J Cell Mol Med. 2019 May 31. doi: 10.1111/jcmm.14423. [Epub ahead of print]
Epub:
Yes
Abstract:
Cytochrome P450 26A1 (CYP26A1) plays important roles in the mice peri-implantation period. Inhibiting its expression or...
Link:
https://onlinelibrary.wiley.com/doi/full/10.1111/jcmm.14423
Delivery Method:
intrauterine injection
Organism or Cell Type:
mice
Citation Extract:
Gu AQ, Li DD, Wei DP, Liu YQ, Ji WH, Yang Y, Lin HY, Peng JP. Cytochrome P450 26A1 modulates uterine dendritic cells in mice early pregnancy. J Cell Mol Med. 2019 May 31. doi: 10.1111/jcmm.14423. [Epub ahead of print].

Sun1 mediates interkinetic nuclear migration and Notch signaling in the neurogenesis of zebrafish

Authors:
You MS, Wang WP, Wang JY, Jiang YJ, Chi YH
Citation:
Stem Cells Dev. 2019 May 29. doi: 10.1089/scd.2019.0063. [Epub ahead of print]
Epub:
Yes
Abstract:
Interkinetic nuclear migration (INM) is a process by which nuclei oscillate between the basal and apical surfaces of epithelial...
Link:
https://www.liebertpub.com/doi/10.1089/scd.2019.0063
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
You MS, Wang WP, Wang JY, Jiang YJ, Chi YH. Sun1 mediates interkinetic nuclear migration and Notch signaling in the neurogenesis of zebrafish. Stem Cells Dev. 2019 May 29. doi: 10.1089/scd.2019.0063. [Epub ahead of print].

A long noncoding RNA cluster-based genomic locus maintains proper development and visual function

Authors:
Wang F, Ren D, Liang X, Ke S, Zhang B, Hu B, Song X, Wang X
Citation:
Nucleic Acids Res. 2019 May 25. pii: gkz444. doi: 10.1093/nar/gkz444. [Epub ahead of print]
Epub:
Yes
Abstract:
Long noncoding RNAs (lncRNAs) represent a group of regulatory RNAs that play critical roles in numerous cellular events, but...
Link:
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkz444/5498619
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang F, Ren D, Liang X, Ke S, Zhang B, Hu B, Song X, Wang X. A long noncoding RNA cluster-based genomic locus maintains proper development and visual function. Nucleic Acids Res. 2019 May 25. pii: gkz444. doi: 10.1093/nar/gkz444. [Epub ahead of print].

Cdc42 Effector Protein 3 Interacts With Cdc42 in Regulating Xenopus Somite Segmentation

Authors:
Kho M, Shi H, Nie S
Citation:
Front Physiol. 2019 May 7;10:542. doi: 10.3389/fphys.2019.00542. eCollection 2019
Epub:
Not Epub
Abstract:
Somitogenesis is a critical process during vertebrate development that establishes the segmented body plan and gives rise to...
Link:
https://www.frontiersin.org/articles/10.3389/fphys.2019.00542/full
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kho M, Shi H, Nie S. Cdc42 Effector Protein 3 Interacts With Cdc42 in Regulating Xenopus Somite Segmentation. Front Physiol. 2019 May 7;10:542. doi: 10.3389/fphys.2019.00542. eCollection 2019.

Coupling Genome-wide Transcriptomics and Developmental Toxicity Profiles in Zebrafish to Characterize Polycyclic Aromatic Hydrocarbon (PAH) Hazard

Authors:
Shankar P, Geier MC, Truong L, McClure RS, Pande P, Waters KM, Tanguay RL
Citation:
Int J Mol Sci. 2019 May 25;20(10). pii: E2570. doi: 10.3390/ijms20102570
Epub:
Not Epub
Abstract:
Polycyclic Aromatic Hydrocarbons (PAHs) are diverse environmental pollutants associated with adverse human health effects. Many...
Link:
https://www.mdpi.com/1422-0067/20/10/2570
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shankar P, Geier MC, Truong L, McClure RS, Pande P, Waters KM, Tanguay RL. Coupling Genome-wide Transcriptomics and Developmental Toxicity Profiles in Zebrafish to Characterize Polycyclic Aromatic Hydrocarbon (PAH) Hazard. Int J Mol Sci. 2019 May 25;20(10). pii: E2570. doi: 10.3390/ijms20102570.

Involvement of Myt1 kinase in the G2 phase of the first cell cycle in Xenopus laevis

Authors:
Yoshitome S, Aiba Y, Yuge M, Furuno N, Watanabe M, Nakajo N
Citation:
Biochem Biophys Res Commun. 2019 May 23. pii: S0006-291X(19)30990-8. doi: 10.1016/j.bbrc.2019.05.104. [Epub ahead of print]
Epub:
Yes
Abstract:
During cleavage of Xenopus laevis, the first mitotic cell cycle immediately following fertilization is approximately 90 min and...
Link:
https://www.sciencedirect.com/science/article/pii/S0006291X19309908
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yoshitome S, Aiba Y, Yuge M, Furuno N, Watanabe M, Nakajo N. Involvement of Myt1 kinase in the G2 phase of the first cell cycle in Xenopus laevis. Biochem Biophys Res Commun. 2019 May 23. pii: S0006-291X(19)30990-8. doi: 10.1016/j.bbrc.2019.05.104. [Epub ahead of print].

Wnt11 regulates cardiac chamber development and disease during perinatal maturation

Authors:
Touma M, Kang X, Gao F, Zhao Y, Cass AA, Biniwale R, Xiao X, Eghbali M, Coppola G, Reemtsen B, Wang Y
Citation:
JCI Insight. 2017 Sep 7;2(17). pii: 94904. doi: 10.1172/jci.insight.94904. eCollection 2017 Sep 7
Epub:
Not Epub
Abstract:
Ventricular chamber growth and development during perinatal circulatory transition is critical for functional adaptation of the...
Link:
https://insight.jci.org/articles/view/94904
Delivery Method:
maternal i.v. for embryo delivery, Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Touma M, Kang X, Gao F, Zhao Y, Cass AA, Biniwale R, Xiao X, Eghbali M, Coppola G, Reemtsen B, Wang Y. Wnt11 regulates cardiac chamber development and disease during perinatal maturation. JCI Insight. 2017 Sep 7;2(17). pii: 94904. doi: 10.1172/jci.insight.94904. eCollection 2017 Sep 7.

Changes in Thyroid Hormone Activity Disrupt Photomotor Behavior of Larval Zebrafish

Authors:
Walter KM, Miller GW, Chen X, Harvey DJ, Puschner B, Lein PJ
Citation:
Neurotoxicology. 2019 May 20. pii: S0161-813X(19)30048-8. doi: 10.1016/j.neuro.2019.05.008. [Epub ahead of print]
Epub:
Yes
Abstract:
High throughput in vitro, in silico, and computational approaches have identified numerous environmental chemicals that...
Link:
https://www.sciencedirect.com/science/article/pii/S0161813X19300488
Organism or Cell Type:
zebrafish
Citation Extract:
Walter KM, Miller GW, Chen X, Harvey DJ, Puschner B, Lein PJ. Changes in Thyroid Hormone Activity Disrupt Photomotor Behavior of Larval Zebrafish. Neurotoxicology. 2019 May 20. pii: S0161-813X(19)30048-8. doi: 10.1016/j.neuro.2019.05.008. [Epub ahead of print].

AcrAB-TolC Inhibition by Peptide-conjugated Phosphorodiamidate Morpholino Oligomers Restores Antibiotic Activity in vitro and in vivo

Authors:
Sturge CR, Felder-Scott CF, Pifer R, Pybus C, Jain R, Geller B, Greenberg D
Citation:
ACS Infect Dis. 2019 May 23. doi: 10.1021/acsinfecdis.9b00123. [Epub ahead of print]
Epub:
Yes
Abstract:
Overexpression of bacterial efflux pumps are a driver of increasing antibiotic resistance in gram-negative pathogens. The AcrAB...
Link:
https://pubs.acs.org/doi/10.1021/acsinfecdis.9b00123
Delivery Method:
peptide-linked
Organism or Cell Type:
Enterobacteriaceae strains, Klebsiella pneumoniae, Pseudomonas aeruginosa
Citation Extract:
Sturge CR, Felder-Scott CF, Pifer R, Pybus C, Jain R, Geller B, Greenberg D. AcrAB-TolC Inhibition by Peptide-conjugated Phosphorodiamidate Morpholino Oligomers Restores Antibiotic Activity in vitro and in vivo. ACS Infect Dis. 2019 May 23. doi: 10.1021/acsinfecdis.9b00123. [Epub ahead of print].

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