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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Aspergillus fumigatus establishes infection in zebrafish by germination of phagocytized conidia, while Aspergillus niger relies on extracellular germination
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Citation:
Sci Rep. 2019;9(1):12791. doi:10.1038/s41598-019-49284-w Epub:
Not Epub Abstract:
Among opportunistically pathogenic filamentous fungi of the Aspergillus genus, Aspergillus fumigatus stands out as a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Koch BEV, Hajdamowicz NH, Lagendijk E, Ram AFJ, Meijer AH. Aspergillus fumigatus establishes infection in zebrafish by germination of phagocytized conidia, while Aspergillus niger relies on extracellular germination. Sci Rep. 2019;9(1):12791. doi:10.1038/s41598-019-49284-w. |
TRPV4-Mediated Detection of Hyposmotic Stress by Skin Keratinocytes Activates Developmental Immunity
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Citation:
J Immunol. 2016 Jan 15;196(2):738-49. doi: 10.4049/jimmunol.1501729. Epub 2015 Dec 16. Erratum in: J Immunol. 2016 Apr 15;196(8):3494 Epub:
Not Epub Abstract:
As an organism is exposed to pathogens during very early development, specific defense mechanisms must take effect. In this... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Galindo-Villegas J, Montalban-Arques A, Liarte S, de Oliveira S, Pardo-Pastor C, Rubio-Moscardo F, Meseguer J, Valverde MA, Mulero V. TRPV4-Mediated Detection of Hyposmotic Stress by Skin Keratinocytes Activates Developmental Immunity. J Immunol. 2016 Jan 15;196(2):738-49. doi: 10.4049/jimmunol.1501729. Epub 2015 Dec 16. Erratum in: J Immunol. 2016 Apr 15;196(8):3494. |
Disruption of splicing-regulatory elements using CRISPR/Cas9 rescues spinal muscular atrophy in human iPSCs and mice
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Citation:
Nat Sci Rev. 2019;[Epub] doi:10.1093/nsr/nwz131 Epub:
Not Epub Abstract:
We here report a genome-editing strategy to correct spinal muscular atrophy (SMA). Rather than directly targeting the... Organism or Cell Type:
cell culture: SMA-2 iPSC Citation Extract: Li J-J, Lin X, Cheng Tang, Lu Y-Q, Hu X, Zuo E, Li H, Ying W, Sun Y, Lai L-L, Chen H-Z, Guo X-X, Zhang Q-J, Wu S, Zhou C, Shen X, Wang Q, Lin M-T, Ma L-X, Wang N, Krainer AR, Shi L, Yang H, Chen W-J. Disruption of splicing-regulatory elements using CRISPR/Cas9 rescues spinal muscular atrophy in human iPSCs and mice. Nat Sci Rev. 2019;[Epub] doi:10.1093/nsr/nwz131. |
Myotubularin related protein 7 is essential for the spermatogonial stem cell homeostasis via PI3K/AKT signaling
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Citation:
Cell Cycle. 2019;[Epub ahead of print] doi:10.1080/15384101.2019.1661174 Epub:
Not Epub Abstract:
Myotubularin related protein 7 (MTMR7), a key member of the MTMR family, depicts phosphatase activity and is involved in... Organism or Cell Type:
mouse testis Citation Extract: Zhao D, Shen C, Gao T, Li H, Guo Y, Li F, Liu C, Liu Y, Chen X, Zhang X, Wu Y, Yu Y, Lin M, Yuan Y, Chen X, Huang X, Yang S, Yu J, Zhang J, Zheng B. Myotubularin related protein 7 is essential for the spermatogonial stem cell homeostasis via PI3K/AKT signaling. Cell Cycle. 2019;[Epub ahead of print] doi:10.1080/15384101.2019.1661174. |
MicroRNA-mediated control of developmental lymphangiogenesis
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Citation:
eLife. 2019;8:e46007. doi: 10.7554/eLife.46007 Epub:
Not Epub Abstract:
The post-transcriptional mechanisms contributing to molecular regulation of developmental lymphangiogenesis and lymphatic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jung HM, Hu CT, Fister AM, Davis AE, Castranova D, Pham VN, Price LM, Weinstein BM. MicroRNA-mediated control of developmental lymphangiogenesis. eLife. 2019;8:e46007. doi: 10.7554/eLife.46007. |
Loss of CENPF leads to developmental failure in mouse embryos
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Citation:
Cell Cycle. 2019;[Epub ahead of print] doi:10.1080/15384101.2019.1661173 Epub:
Yes Abstract:
Aneuploidy caused by abnormal chromosome segregation during early embryo development leads to embryonic death or congenital... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte, embryo Citation Extract: Zhou C-J, Wang X-Y, Han Z, Wang D-H, Ma Y-Z, Liang C-G. Loss of CENPF leads to developmental failure in mouse embryos. Cell Cycle. 2019;[Epub ahead of print] doi:10.1080/15384101.2019.1661173. |
Peptide-conjugated oligonucleotides evoke long-lasting myotonic dystrophy correction in patient-derived cells and mice
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Citation:
J Clin Invest. 2019 Nov 1;129(11):4739-4744. doi: 10.1172/JCI128205 Epub:
Not Epub Abstract:
Antisense oligonucleotides (ASOs) targeting pathologic RNAs have shown promising therapeutic corrections for many genetic... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: patient-derived muscle DM1 mice Citation Extract: Klein AF, Varela MA, Arandel L, Holland A, Naouar N, Arzumanov A, Seoane D, Revillod L, Bassez G, Ferry A, Jauvin D, Gourdon G, Puymirat J, Gait MJ, Furling D, Wood MJA. Peptide-conjugated oligonucleotides evoke long-lasting myotonic dystrophy correction in patient-derived cells and mice. J Clin Invest. 2019 Nov 1;129(11):4739-4744. doi: 10.1172/JCI128205. |
Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis
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Citation:
PLoS ONE. 2019;14(8):e0221698. doi:10.1371/journal.pone.0221698 Epub:
Not Epub Abstract:
Kidneys are composed of numerous ciliated epithelial tubules called nephrons. Each nephron functions to reabsorb nutrients and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Corkins ME, Krneta-Stankic V, Kloc M, McCrea PD, Gladden AB, Miller RK. Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis. PLoS ONE. 2019;14(8):e0221698. doi:10.1371/journal.pone.0221698. |
ARHGEF12 regulates erythropoiesis and is involved in erythroid regeneration after chemotherapy in acute lymphoblastic leukemia patients
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Citation:
Haematologica. 2019 Aug 29. pii: haematol.2018.210286. doi: 10.3324/haematol.2018.210286. [Epub ahead of print] Epub:
Yes Abstract:
Hematopoiesis is a finely regulated process in vertebrates under both homeostatic and stress conditions. By whole exome... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xie Y, Gao L, Xu C, Chu L, Gao L, Wu R, Liu Y, Liu T, Sun XJ, Ren R, Tang J, Zheng Y, Zhou Y, Shen S. ARHGEF12 regulates erythropoiesis and is involved in erythroid regeneration after chemotherapy in acute lymphoblastic leukemia patients. Haematologica. 2019 Aug 29. pii: haematol.2018.210286. doi: 10.3324/haematol.2018.210286. [Epub ahead of print]. |
Non-junctional Cadherin3 regulates cell migration and contact inhibition of locomotion via domain-dependent opposing regulations of Rac1
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/750752 Epub:
Not Epub Abstract:
Classical cadherins are well-known primary adhesion molecules responsible for physically connecting neighboring cells and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Ichikawa T, Stuckenholz C, Davidson LA. Non-junctional Cadherin3 regulates cell migration and contact inhibition of locomotion via domain-dependent opposing regulations of Rac1. bioRxiv. 2019;[preprint] doi:10.1101/750752. |