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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

EvpP inhibits neutrophils recruitment via Jnk-caspy inflammasome signaling in vivo

Authors:
Tan J, Yang D, Wang Z, Zheng X, Zhang Y, Liu Q
Citation:
Fish & Shellfish Immunol. 2019;[Epub ahead of print] doi:10.1016/j.fsi.2019.05.051
Epub:
Yes
Abstract:
Innate immunity is regulated by phagocytic cells and is critical for host control of bacterial infection. In many bacteria, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tan J, Yang D, Wang Z, Zheng X, Zhang Y, Liu Q. EvpP inhibits neutrophils recruitment via Jnk-caspy inflammasome signaling in vivo. Fish & Shellfish Immunol. 2019;[Epub ahead of print] doi:10.1016/j.fsi.2019.05.051.

Specific miRNA-GPCR networks regulate Sox9a/Sox9b activities to promote gonadal rejuvenation in zebrafish

Authors:
Guo H, Du X, Zhang Y, Wu J, Wang C, Li M, Hua X, Zhang XA, Yan J
Citation:
Stem Cells. 2019 May 22. doi: 10.1002/stem.3040. [Epub ahead of print]
Epub:
Yes
Abstract:
Fertility and endocrine function rely on a tightly regulated synchronicity within the hypothalamic-pituitary gonadal (HPG) axis...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Guo H, Du X, Zhang Y, Wu J, Wang C, Li M, Hua X, Zhang XA, Yan J. Specific miRNA-GPCR networks regulate Sox9a/Sox9b activities to promote gonadal rejuvenation in zebrafish. Stem Cells. 2019 May 22. doi: 10.1002/stem.3040. [Epub ahead of print].

Loss of abcd4 in zebrafish leads to vitamin B12-deficiency anemia

Authors:
Choi YM, Kim YI, Choi JH, Bhandari S, Nam IK, Hong K, Kwak S, So HS, Park DS, Kim CH, Choi TY, Choe SK
Citation:
Biochem Biophys Res Commun. 2019 May 18. pii: S0006-291X(19)30979-9. doi: 10.1016/j.bbrc.2019.05.099. [Epub ahead of print]
Epub:
Yes
Abstract:
ABCD4, a member of the ATP-binding cassette transporter superfamily, is associated with the transport of vitamin B12 which is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Choi YM, Kim YI, Choi JH, Bhandari S, Nam IK, Hong K, Kwak S, So HS, Park DS, Kim CH, Choi TY, Choe SK. Loss of abcd4 in zebrafish leads to vitamin B12-deficiency anemia. Biochem Biophys Res Commun. 2019 May 18. pii: S0006-291X(19)30979-9. doi: 10.1016/j.bbrc.2019.05.099. [Epub ahead of print].

Japanese Encephalitis Virus-induced let-7a/b interacted with the NOTCH-TLR7 pathway in microglia and facilitated neuronal death via caspase activation

Authors:
Mukherjee S, Akbar I, Kumari B, Vrati S, Basu A, Banerjee A
Citation:
J Neurochem. 2018 Dec 17. doi: 10.1111/jnc.14645. [Epub ahead of print]
Epub:
Yes
Abstract:
MicroRNAs (miRNAs) released from the activated microglia upon neurotropic virus infection may exacerbate the neuronal damage....
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice (brain)
Citation Extract:
Mukherjee S, Akbar I, Kumari B, Vrati S, Basu A, Banerjee A. Japanese Encephalitis Virus-induced let-7a/b interacted with the NOTCH-TLR7 pathway in microglia and facilitated neuronal death via caspase activation. J Neurochem. 2018 Dec 17. doi: 10.1111/jnc.14645. [Epub ahead of print].

Essential role of prostaglandin E2 and the EP3 receptor in lymphatic vessel development during zebrafish embryogenesis

Authors:
Iwasaki R, Tsuge K, Kishimoto K, Hayashi Y, Iwaana T, Hohjoh H, Inazumi T, Kawahara A, Tsuchiya S, Sugimoto Y
Citation:
Sci Rep. 2019;9(1):7650 doi:10.1038/s41598-019-44095-5
Epub:
Not Epub
Abstract:
Lymphatic endothelial cells arise from the venous endothelial cells in embryonic lymphatic development. However, the molecular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Iwasaki R, Tsuge K, Kishimoto K, Hayashi Y, Iwaana T, Hohjoh H, Inazumi T, Kawahara A, Tsuchiya S, Sugimoto Y. Essential role of prostaglandin E2 and the EP3 receptor in lymphatic vessel development during zebrafish embryogenesis. Sci Rep. 2019;9(1):7650 doi:10.1038/s41598-019-44095-5.

Genome-Wide Association Study-Driven Gene-Set Analyses, Genetic, and Functional Follow-Up Suggest GLIS1 as a Susceptibility Gene for Mitral Valve Prolapse

Authors:
Yu M, Georges A, Tucker NR, Kyryachenko S, Toomer K, Schott JJ, Delling FN, Fernandez-Friera L, Solis J, Ellinor PT, Levine RA, Slaugenhaupt SA, Hagège AA, Dina C, Jeunemaitre X, Milan DJ, Norris RA, Bouatia-Naji N
Citation:
Circ Genom Precis Med. 2019 May;12(5):e002497. doi: 10.1161/CIRCGEN.119.002497
Epub:
Not Epub
Abstract:
Background: Mitral valve prolapse (MVP) is a common heart valve disease, the most frequent indication for valve repair or...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yu M, Georges A, Tucker NR, Kyryachenko S, Toomer K, Schott JJ, Delling FN, Fernandez-Friera L, Solis J, Ellinor PT, Levine RA, Slaugenhaupt SA, Hagège AA, Dina C, Jeunemaitre X, Milan DJ, Norris RA, Bouatia-Naji N. Genome-Wide Association Study-Driven Gene-Set Analyses, Genetic, and Functional Follow-Up Suggest GLIS1 as a Susceptibility Gene for Mitral Valve Prolapse. Circ Genom Precis Med. 2019 May;12(5):e002497. doi: 10.1161/CIRCGEN.119.002497.

The Innate Immune Response of Frog Embryos to Antisense Morpholino Oligomers Depends on Developmental Stage, GC Content and Dose

Authors:
Gentsch GE, Spruce T, Owens NDL, Monteiro RS, Smith JC
Citation:
Dev Cell. 2019;49(4):506-7. doi:10.1016/j.devcel.2019.05.004
Epub:
Not Epub
Abstract:
In this issue of Developmental Cell, Paraiso and colleagues report that antisense morpholino oligomers (MOs), frequently used...
Organism or Cell Type:
Xenopus
Citation Extract:
Gentsch GE, Spruce T, Owens NDL, Monteiro RS, Smith JC. The Innate Immune Response of Frog Embryos to Antisense Morpholino Oligomers Depends on Developmental Stage, GC Content and Dose. Dev Cell. 2019;49(4):506-7. doi:10.1016/j.devcel.2019.05.004.

Morpholinos Do Not Elicit an Innate Immune Response during Early Xenopus Embryogenesis

Authors:
Paraiso KD, Blitz IL, Zhou JJ, Cho KWY
Citation:
Dev Cell. 2019;49(4):643-50. doi:10.1016/j.devcel.2019.04.019
Epub:
Not Epub
Abstract:
It has recently been reported that a common side effect of translation-blocking morpholino antisense oligonucleotides is the...
Organism or Cell Type:
Xenopus
Citation Extract:
Paraiso KD, Blitz IL, Zhou JJ, Cho KWY. Morpholinos Do Not Elicit an Innate Immune Response during Early Xenopus Embryogenesis. Dev Cell. 2019;49(4):643-50. doi:10.1016/j.devcel.2019.04.019.

Combined antisense knockdown of type 1 and type 2 iodothyronine deiodinases disrupts embryonic development in zebrafish (Danio rerio)

Authors:
Walpita CN, Crawford AD, Darras VM
Citation:
Gen Comp Endocrinol. 2010 Mar 1;166(1):134-41. doi: 10.1016/j.ygcen.2009.09.011. Epub 2009 Oct 1
Epub:
Not Epub
Abstract:
Thyroid hormones (THs) are important regulators of gene expression during vertebrate development. In teleosts, early embryos...
Organism or Cell Type:
zebrafish
Citation Extract:
Walpita CN, Crawford AD, Darras VM. Combined antisense knockdown of type 1 and type 2 iodothyronine deiodinases disrupts embryonic development in zebrafish (Danio rerio). Gen Comp Endocrinol. 2010 Mar 1;166(1):134-41. doi: 10.1016/j.ygcen.2009.09.011. Epub 2009 Oct 1.

EGFR is required for Wnt9a–Fzd9b signalling specificity in haematopoietic stem cells

Authors:
Grainger S, Nguyen N, Richter J, Setayesh J, Lonquich B, Oon CH, Wozniak JM, Barahona R, Kamei CN, Houston J, Carrillo-Terrazas M, Drummond IA, Gonzalez D, Willert K, Traver D
Citation:
Nat Cell Biol. 2019;[Ebut ahead of print] doi:10.1038/s41556-019-0330-5
Epub:
Yes
Abstract:
Wnt signalling drives many processes in development, homeostasis and disease; however, the role and mechanism of individual...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Grainger S, Nguyen N, Richter J, Setayesh J, Lonquich B, Oon CH, Wozniak JM, Barahona R, Kamei CN, Houston J, Carrillo-Terrazas M, Drummond IA, Gonzalez D, Willert K, Traver D. EGFR is required for Wnt9a–Fzd9b signalling specificity in haematopoietic stem cells. Nat Cell Biol. 2019;[Ebut ahead of print] doi:10.1038/s41556-019-0330-5.

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