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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Triptolide preserves glomerular barrier function via the inhibition of p53-mediated increase of GADD45B
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Citation:
Arch Biochem Biophys. 2019 Jul 19;671:210-217. doi: 10.1016/j.abb.2019.07.012. [Epub ahead of print] Epub:
Not Epub Abstract:
Podocytes are important to glomerular filtration barrier integrity and maintenance of size selectivity in protein filtration in... Organism or Cell Type:
zebrafish Citation Extract: Zhai X, Wang L, Xu C, Hou Q, Zhang L, Li Z, Qin W, Liu Z, Chen Z. Triptolide preserves glomerular barrier function via the inhibition of p53-mediated increase of GADD45B. Arch Biochem Biophys. 2019 Jul 19;671:210-217. doi: 10.1016/j.abb.2019.07.012. [Epub ahead of print]. |
Exons 45-55 skipping using mutation-tailored cocktails of antisense morpholinos in the DMD gene
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Citation:
Molec Ther. 2019;[Epub ahead of print] doi:10.1016/j.ymthe.2019.07.012 Epub:
Yes Abstract:
Mutations in the dystrophin (DMD) gene and consequent loss of dystrophin cause Duchenne muscular dystrophy (DMD). A promising... Organism or Cell Type:
cell culture Citation Extract: Echigoya Y, Lim KRQ, Melo D, Bao B, Trieu N, Mizobe Y, Maruyama R, Mamchaoui K, Tanihata J, Aoki Y, Takeda S, Mouly V, Duddy W, Yokota T. Exons 45-55 skipping using mutation-tailored cocktails of antisense morpholinos in the DMD gene. Molec Ther. 2019;[Epub ahead of print] doi:10.1016/j.ymthe.2019.07.012. |
The Edwardsiella piscicida thioredoxin-like protein inhibits ASK1-MAPKs signaling cascades to promote pathogenesis during infection
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Citation:
PLoS Pathog. 2019;15(7):e1007917. doi:10.1371/journal.ppat.1007917 Epub:
Not Epub Abstract:
It is important that bacterium can coordinately deliver several effectors into host cells to disturb the cellular progress... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang D, Liu X, Xu W, Gu Z, Yang C, Zhang L, Tan J, Zheng X, Wang Z, Quan S, Zhang Y, Liu Q. The Edwardsiella piscicida thioredoxin-like protein inhibits ASK1-MAPKs signaling cascades to promote pathogenesis during infection. PLoS Pathog. 2019;15(7):e1007917. doi:10.1371/journal.ppat.1007917. |
SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication
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Citation:
Nat Comm. 2019;10(1):3142. doi:10.1038/s41467-019-11095-y Epub:
Not Epub Abstract:
The SPRTN metalloprotease is essential for DNA-protein crosslink (DPC) repair and DNA replication in vertebrate cells. Cells... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Halder S, Torrecilla I, Burkhalter MD, Popović M, Fielden J, Vaz B, Oehler J, Pilger D, Lessel D, Wiseman K, Singh AN, Vendrell I, Fischer R, Philipp M, Ramadan K. SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication. Nat Comm. 2019;10(1):3142. doi:10.1038/s41467-019-11095-y. |
Functions of thioredoxin1 in brain development and in response to environmental chemicals in zebrafish embryos
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Citation:
Toxicol Lett. 2019:[Epub ahead of print] doi:10.1016/j.toxlet.2019.07.009 Epub:
Yes Abstract:
Thioredoxin is an evolutionarily conserved antioxidant protein that plays a crucial role for fundamental cellular processes and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang L, Zeng C, Zhang Y, Wang F, Takamiya M, Strähle U. Functions of thioredoxin1 in brain development and in response to environmental chemicals in zebrafish embryos. Toxicol Lett. 2019:[Epub ahead of print] doi:10.1016/j.toxlet.2019.07.009. |
The splicing factor Sf3b1 regulates erythroid maturation and proliferation via TGFβ signaling in zebrafish
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Citation:
Blood Adv. 2019 Jul 23;3(14):2093-2104. doi: 10.1182/bloodadvances.2018027714 Epub:
Not Epub Abstract:
The spliceosomal component Splicing Factor 3B, subunit 1 (SF3B1) is one of the most prevalently mutated factors in the bone... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: De La Garza A, Cameron RC, Gupta V, Fraint E, Nik S, Bowman TV. The splicing factor Sf3b1 regulates erythroid maturation and proliferation via TGFβ signaling in zebrafish. Blood Adv. 2019 Jul 23;3(14):2093-2104. doi: 10.1182/bloodadvances.2018027714. |
Topologically correct central projections of tetrapod inner ear afferents require Fzd3
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Citation:
Sci Rep. 2019;9(1):10298. doi:10.1038/s41598-019-46553-6 Epub:
Not Epub Abstract:
Inner ear sensory afferent connections establish sensory maps between the inner ear hair cells and the vestibular and auditory... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Duncan JS, Fritzsch B, Houston DW, Ketchum EM, Kersigo J, Deans MR, Elliott KL. Topologically correct central projections of tetrapod inner ear afferents require Fzd3. Sci Rep. 2019;9(1):10298. doi:10.1038/s41598-019-46553-6. |
The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand
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Citation:
Addict Biol. 2019 Jul 11:e12795. doi: 10.1111/adb.12795. [Epub ahead of print] Epub:
Yes Abstract:
Lateral hypothalamus (LH) orexin neuron signaling has been implicated in the motivation to seek and take drugs of abuse. The... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Rats Sprague-Dawley male Citation Extract: Pantazis CB, James MH, Bentzley BS, Aston-Jones G. The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand. Addict Biol. 2019 Jul 11:e12795. doi: 10.1111/adb.12795. [Epub ahead of print]. |
The human nephrin Y1139RSL motif is essential for podocyte foot process organization and slit diaphragm formation during glomerular development
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Citation:
J Biol Chem. 2019 May 31. pii: jbc.RA119.008235. doi: 10.1074/jbc.RA119.008235. [Epub ahead of print] Epub:
Yes Abstract:
Nephrin is an immunoglobulin-type cell-adhesion molecule with a key role in the glomerular interpodocyte slit diaphragm.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Espiritu EB, Jiang H, Moreau-Marquis S, Sullivan M, Yan K, Beer Stolz D, Sampson MG, Hukriede NA, Swiatecka-Urban A. The human nephrin Y1139RSL motif is essential for podocyte foot process organization and slit diaphragm formation during glomerular development. J Biol Chem. 2019 May 31. pii: jbc.RA119.008235. doi: 10.1074/jbc.RA119.008235. [Epub ahead of print]. |
Pectoral Fin Anomalies in tbx5a Knockdown Zebrafish Embryos Related to the Cascade Effect of N-Cadherin and Extracellular Matrix Formation
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Citation:
J Dev Biol. 2019;7(3):[Epub ahead of print] doi:10.3390/jdb7030015 Epub:
Yes Abstract:
Functional knockdown of zebrafish tbx5a causes hypoplasia or aplasia of pectoral fins. This study aimed to assess developmental... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lu JK, Tsai T-C, Lee H, Hsia K, Lin C-H, Lu J-H. Pectoral Fin Anomalies in tbx5a Knockdown Zebrafish Embryos Related to the Cascade Effect of N-Cadherin and Extracellular Matrix Formation. J Dev Biol. 2019;7(3):[Epub ahead of print] doi:10.3390/jdb7030015. |