You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

ΔN-Tp63 mediates Wnt/β-catenin-induced inhibition of differentiation in basal stem cells of mucociliary epithelia

Authors:
Haas M, Vázquez JLG, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/682534
Epub:
Not Epub
Abstract:
Mucociliary epithelia provide a first line of defense against pathogens in the airways and the epidermis of vertebrate larvae....
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Haas M, Vázquez JLG, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P. ΔN-Tp63 mediates Wnt/β-catenin-induced inhibition of differentiation in basal stem cells of mucociliary epithelia. bioRxiv. 2019;[preprint] doi:10.1101/682534.

Dephosphorylation of HDAC4 by PP2A-Bδ unravels a new role for the HDAC4/MEF2 axis in myoblast fusion

Authors:
Veloso A, Martin M, Bruyr J, O’Grady T, Deroanne C, Mottet D, Twizere J-C, Cherrier T, Dequiedt F
Citation:
Cell Death & Dis. 2019;10(7):512. doi:10.1038/s41419-019-1743-6
Epub:
Not Epub
Abstract:
Muscle formation is controlled by a number of key myogenic transcriptional regulators that govern stage-specific gene...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Veloso A, Martin M, Bruyr J, O’Grady T, Deroanne C, Mottet D, Twizere J-C, Cherrier T, Dequiedt F. Dephosphorylation of HDAC4 by PP2A-Bδ unravels a new role for the HDAC4/MEF2 axis in myoblast fusion. Cell Death & Dis. 2019;10(7):512. doi:10.1038/s41419-019-1743-6.

NIPBL: a new player in myeloid cell differentiation

Authors:
Mazzola M, Deflorian G, Pezzotta A, Ferrari L, Fazio G, Bresciani E, Saitta C, Ferrari L, Fumagalli M, Parma M, Marasca F, Bodega B, Riva P, Cotelli F, Biondi A, Marozzi A, Cazzaniga G, Pistocchi A
Citation:
Haematologica. 2019 Jul;104(7):1332-1341. doi: 10.3324/haematol.2018.200899. Epub 2019 Jan 10
Epub:
Not Epub
Abstract:
The nucleophosmin 1 gene (NPM1) is the most frequently mutated gene in acute myeloid leukemia. Notably, NPM1 mutations are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mazzola M, Deflorian G, Pezzotta A, Ferrari L, Fazio G, Bresciani E, Saitta C, Ferrari L, Fumagalli M, Parma M, Marasca F, Bodega B, Riva P, Cotelli F, Biondi A, Marozzi A, Cazzaniga G, Pistocchi A. NIPBL: a new player in myeloid cell differentiation. Haematologica. 2019 Jul;104(7):1332-1341. doi: 10.3324/haematol.2018.200899. Epub 2019 Jan 10.

DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract

Authors:
Blackburn ATM, Bekheirnia N, Uma VC, Corkins ME, Xu Y, Rosenfeld JA, Bainbridge MN, Yang Y, Liu P, Madan-Khetarpal S, Delgado MR, Hudgins L, Krantz I, Rodriguez-Buritica D, Wheeler PG, Gazali LA, Mohamed Saeed Mohamed Al Shamsi A, Gomez-Ospina N, Chao HT, Mirzaa GM, Scheuerle AE, Kukolich MK, Scaglia F, Eng C, Willsey HR, Braun MC, Lamb DJ, Miller RK, Bekheirnia MR
Citation:
Genet Med. 2019 Jul 2. doi: 10.1038/s41436-019-0576-0. [Epub ahead of print]
Epub:
Yes
Abstract:
PURPOSE: Haploinsufficiency of DYRK1A causes a recognizable clinical syndrome. The goal of this paper is to investigate...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Blackburn ATM, Bekheirnia N, Uma VC, Corkins ME, Xu Y, Rosenfeld JA, Bainbridge MN, Yang Y, Liu P, Madan-Khetarpal S, Delgado MR, Hudgins L, Krantz I, Rodriguez-Buritica D, Wheeler PG, Gazali LA, Mohamed Saeed Mohamed Al Shamsi A, Gomez-Ospina N, Chao HT, Mirzaa GM, Scheuerle AE, Kukolich MK, Scaglia F, Eng C, Willsey HR, Braun MC, Lamb DJ, Miller RK, Bekheirnia MR. DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract. Genet Med. 2019 Jul 2. doi: 10.1038/s41436-019-0576-0. [Epub ahead of print].

Developmentally regulated GTP-binding protein 1 modulates ciliogenesis via an interaction with Dishevelled

Authors:
Lee M, Hwang YS, Yoon J, Sun J, Harned A, Nagashima K, Daar IO
Citation:
J Cell Biol. 2019 Jul 3. pii: jcb.201811147. doi: 10.1083/jcb.201811147. [Epub ahead of print]
Epub:
Yes
Abstract:
Cilia are critical for proper embryonic development and maintaining homeostasis. Although extensively studied, there are still...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Lee M, Hwang YS, Yoon J, Sun J, Harned A, Nagashima K, Daar IO. Developmentally regulated GTP-binding protein 1 modulates ciliogenesis via an interaction with Dishevelled. J Cell Biol. 2019 Jul 3. pii: jcb.201811147. doi: 10.1083/jcb.201811147. [Epub ahead of print].

Long-term treatment with eteplirsen in nonambulatory patients with Duchenne muscular dystrophy

Authors:
Alfano LN, Charleston JS, Connolly AM, Cripe L, Donoghue C, Dracker R, Dworzak J, Eliopoulos H, Frank DE, Lewis S, Lucas K, Lynch J, Milici AJ, Flynt A, Naughton E, Rodino-Klapac LR, Sahenk Z, Schnell FJ, Young GD, Mendell JR, Lowes LP
Citation:
Medicine (Baltimore). 2019 Jun;98(26):e15858. doi: 10.1097/MD.0000000000015858
Epub:
Not Epub
Abstract:
This analysis aims to describe the outcomes of two nonambulatory patients with Duchenne muscular dystrophy (DMD) who...
Delivery Method:
i.v. infusion
Organism or Cell Type:
human
Citation Extract:
Alfano LN, Charleston JS, Connolly AM, Cripe L, Donoghue C, Dracker R, Dworzak J, Eliopoulos H, Frank DE, Lewis S, Lucas K, Lynch J, Milici AJ, Flynt A, Naughton E, Rodino-Klapac LR, Sahenk Z, Schnell FJ, Young GD, Mendell JR, Lowes LP. Long-term treatment with eteplirsen in nonambulatory patients with Duchenne muscular dystrophy. Medicine (Baltimore). 2019 Jun;98(26):e15858. doi: 10.1097/MD.0000000000015858.

Functional muscle recovery following dystrophin and myostatin exon splice modulation in aged mdx mice

Authors:
Lu-Nguyen N, Ferry A, Schnell FJ, Hanson GJ, Popplewell L, Dickson G, Malerba A
Citation:
Hum Mol Genet. 2019 Jun 10. pii: ddz125. doi: 10.1093/hmg/ddz125. [Epub ahead of print]
Epub:
Yes
Abstract:
Duchenne muscular dystrophy (DMD) is a rare genetic disease affecting 1 in 3500-5000 newborn boys. It is due to mutations in...
Organism or Cell Type:
mice mdx
Citation Extract:
Lu-Nguyen N, Ferry A, Schnell FJ, Hanson GJ, Popplewell L, Dickson G, Malerba A. Functional muscle recovery following dystrophin and myostatin exon splice modulation in aged mdx mice. Hum Mol Genet. 2019 Jun 10. pii: ddz125. doi: 10.1093/hmg/ddz125. [Epub ahead of print].

STIM1 Is Required for Remodeling of the Endoplasmic Reticulum and Microtubule Cytoskeleton in Steering Growth Cones

Authors:
Pavez M, Thompson AC, Arnott HJ, Mitchell CB, D'Atri I, Don EK, Chilton JK, Scott EK, Lin JY, Young KM, Gasperini RJ, Foa L
Citation:
J Neurosci. 2019 Jun 26;39(26):5095-5114. doi: 10.1523/JNEUROSCI.2496-18.2019. Epub 2019 Apr 25
Epub:
Not Epub
Abstract:
The spatial and temporal regulation of calcium signaling in neuronal growth cones is essential for axon guidance. In growth...
Citation Extract:
Pavez M, Thompson AC, Arnott HJ, Mitchell CB, D'Atri I, Don EK, Chilton JK, Scott EK, Lin JY, Young KM, Gasperini RJ, Foa L. STIM1 Is Required for Remodeling of the Endoplasmic Reticulum and Microtubule Cytoskeleton in Steering Growth Cones. J Neurosci. 2019 Jun 26;39(26):5095-5114. doi: 10.1523/JNEUROSCI.2496-18.2019. Epub 2019 Apr 25.

The Xenopus Nieuwkoop center and Spemann-Mangold organizer share molecular components and a requirement for maternal Wnt activity

Authors:
Vonica A, Gumbiner BM
Citation:
Dev Biol. 2007 Dec 1;312(1):90-102. Epub 2007 Oct 2
Epub:
Not Epub
Abstract:
In Xenopus embryos, the dorso-ventral and antero-posterior axes are established by the Spemann-Mangold organizer. According to...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Vonica A, Gumbiner BM. The Xenopus Nieuwkoop center and Spemann-Mangold organizer share molecular components and a requirement for maternal Wnt activity. Dev Biol. 2007 Dec 1;312(1):90-102. Epub 2007 Oct 2.

Global analysis of polysome-associated mRNA in vesicular stomatitis virus infected cells

Authors:
Neidermyer WJ Jr, Whelan SPJ
Citation:
PLoS Pathog. 2019;15(6):e1007875. doi:10.1371/journal.ppat.1007875
Epub:
Not Epub
Abstract:
Infection of mammalian cells with vesicular stomatitis virus (VSV) results in the inhibition of cellular translation while...
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Neidermyer WJ Jr, Whelan SPJ. Global analysis of polysome-associated mRNA in vesicular stomatitis virus infected cells. PLoS Pathog. 2019;15(6):e1007875. doi:10.1371/journal.ppat.1007875.

Pages