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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12153 scientific papers returned from the database with the search filters currently being used below.

Induction of interferon-stimulated genes and cellular stress pathways by morpholinos in zebrafish

Authors:
Lai JKH, Gagalova KK, Kuenne C, El-Brolosy MA, Stainier DYR
Citation:
Dev Biol. 2019 Jun 12. pii: S0012-1606(18)30841-8. doi: 10.1016/j.ydbio.2019.06.008. [Epub ahead of print]
Epub:
Yes
Abstract:
The phenotypes caused by morpholino-mediated interference of gene function in zebrafish are often not observed in the...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160618308418
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lai JKH, Gagalova KK, Kuenne C, El-Brolosy MA, Stainier DYR. Induction of interferon-stimulated genes and cellular stress pathways by morpholinos in zebrafish. Dev Biol. 2019 Jun 12. pii: S0012-1606(18)30841-8. doi: 10.1016/j.ydbio.2019.06.008. [Epub ahead of print].

Characterization of paralogous uncx transcription factor encoding genes in zebrafish

Authors:
Nittoli V, Fortunato AE, Fasano G, Coppola U, Gentile A, Maiella S, Langellotto F, Porreca I, De Paolo R, Marino R, Fiengo M, Donizetti A, Aniello F, Kondo T, Ristoratore F, Canzoniero LMT, Duboule D, Wilson SW, Sordino P
Citation:
Gene X. 2019 Jun;2:100011. doi: 10.1016/j.gene.2019.100011
Epub:
Not Epub
Abstract:
The paired-type homeodomain transcription factor Uncx is involved in multiple processes of embryogenesis in vertebrates....
Link:
https://www.sciencedirect.com/science/article/pii/S2590158319300087
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nittoli V, Fortunato AE, Fasano G, Coppola U, Gentile A, Maiella S, Langellotto F, Porreca I, De Paolo R, Marino R, Fiengo M, Donizetti A, Aniello F, Kondo T, Ristoratore F, Canzoniero LMT, Duboule D, Wilson SW, Sordino P. Characterization of paralogous uncx transcription factor encoding genes in zebrafish. Gene X. 2019 Jun;2:100011. doi: 10.1016/j.gene.2019.100011.

Actin dynamics and the Bmp pathway drive apical extrusion of proepicardial cells

Authors:
Andrés-Delgado L, Ernst A, Galardi-Castilla M, Bazaga D, Peralta M, Münch J, González-Rosa JM, Marques I, Tessadori F, de la Pompa JL, Vermot J, Mercader N
Citation:
Development. 2019;[Epub ahead of print] doi:10.1242/dev.174961
Epub:
Yes
Abstract:
The epicardium, the outer mesothelial layer enclosing the myocardium, plays key roles in heart development and regeneration....
Link:
http://dev.biologists.org/content/early/2019/06/06/dev.174961
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Andrés-Delgado L, Ernst A, Galardi-Castilla M, Bazaga D, Peralta M, Münch J, González-Rosa JM, Marques I, Tessadori F, de la Pompa JL, Vermot J, Mercader N. Actin dynamics and the Bmp pathway drive apical extrusion of proepicardial cells. Development. 2019;[Epub ahead of print] doi:10.1242/dev.174961.

Activation of P-TEFb by cAMP-PKA signaling in autosomal dominant polycystic kidney disease

Authors:
Sun Y, Liu Z, Cao X, Lu Y, Mi Z, He C, Liu J, Zheng Z, Li MJ, Li T, Xu D, Wu M, Cao Y, Li Y, Yang B, Mei C, Zhang L, Chen Y
Citation:
Sci Adv. 2019:5(6):eaaw3593 doi:10.1126/sciadv.aaw3593
Epub:
Not Epub
Abstract:
Positive transcription elongation factor b (P-TEFb) functions as a central regulator of transcription elongation. Activation of...
Link:
https://advances.sciencemag.org/content/5/6/eaaw3593
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun Y, Liu Z, Cao X, Lu Y, Mi Z, He C, Liu J, Zheng Z, Li MJ, Li T, Xu D, Wu M, Cao Y, Li Y, Yang B, Mei C, Zhang L, Chen Y. Activation of P-TEFb by cAMP-PKA signaling in autosomal dominant polycystic kidney disease. Sci Adv. 2019:5(6):eaaw3593 doi:10.1126/sciadv.aaw3593.

Endodermal Maternal Transcription Factors Establish Super-Enhancers during Zygotic Genome Activation

Authors:
Paraiso KD, Blitz IL, Coley M, Cheung J, Sudou N, Taira M, Cho KWY
Citation:
Cell Rep. 2019;27(10):2962-77. doi:10.1016/j.celrep.2019.05.013
Epub:
Not Epub
Abstract:
Elucidation of the sequence of events underlying the dynamic interaction between transcription factors and chromatin states is...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(19)30624-2
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Paraiso KD, Blitz IL, Coley M, Cheung J, Sudou N, Taira M, Cho KWY. Endodermal Maternal Transcription Factors Establish Super-Enhancers during Zygotic Genome Activation. Cell Rep. 2019;27(10):2962-77. doi:10.1016/j.celrep.2019.05.013.

Proteolytic and Opportunistic Breaching of the Basement Membrane Zone by Immune Cells during Tumor Initiation

Authors:
van den Berg MCW, MacCarthy-Morrogh L, Carter D, Morris J, Bravo IR, Feng Y, Martin P
Citation:
Cell Rep. 2019;27:2837-46. doi:10.1016/j.celrep.2019.05.029
Epub:
Not Epub
Abstract:
Cancer-related inflammation impacts significantly on cancer development and progression. From early stages, neutrophils and...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(19)30640-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
van den Berg MCW, MacCarthy-Morrogh L, Carter D, Morris J, Bravo IR, Feng Y, Martin P. Proteolytic and Opportunistic Breaching of the Basement Membrane Zone by Immune Cells during Tumor Initiation. Cell Rep. 2019;27:2837-46. doi:10.1016/j.celrep.2019.05.029.

Atypical Chemokine Receptor 3 Generates Guidance Cues for CXCL12-Mediated Endothelial Cell Migration

Authors:
Tobia C, Chiodelli P, Barbieri A, Buraschi S, Ferrari E, Mitola S, Borsani G, Guerra J, Presta M
Citation:
Front Immunol. 2019 May 15;10:1092. doi: 10.3389/fimmu.2019.01092. eCollection 2019
Epub:
Not Epub
Abstract:
Chemokine receptor CXCR4, its ligand stromal cell-derived factor-1 (CXCL12) and the decoy receptor atypical chemokine receptor...
Link:
https://www.frontiersin.org/articles/10.3389/fimmu.2019.01092/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tobia C, Chiodelli P, Barbieri A, Buraschi S, Ferrari E, Mitola S, Borsani G, Guerra J, Presta M. Atypical Chemokine Receptor 3 Generates Guidance Cues for CXCL12-Mediated Endothelial Cell Migration. Front Immunol. 2019 May 15;10:1092. doi: 10.3389/fimmu.2019.01092. eCollection 2019.

RAB35 depletion affects spindle formation and actin-based spindle migration in mouse oocyte meiosis

Authors:
Zhang Y, Wan X, Wang HH, Pan MH, Pan ZN, Sun SC
Citation:
Mol Hum Reprod. 2019 Jun 1. pii: gaz027. doi: 10.1093/molehr/gaz027. [Epub ahead of print]
Epub:
Yes
Abstract:
Mammalian oocyte maturation involves a unique asymmetric cell division, in which meiotic spindle formation and actin filament-...
Link:
https://academic.oup.com/molehr/advance-article-abstract/doi/10.1093/molehr/gaz027/5506450
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Zhang Y, Wan X, Wang HH, Pan MH, Pan ZN, Sun SC. RAB35 depletion affects spindle formation and actin-based spindle migration in mouse oocyte meiosis. Mol Hum Reprod. 2019 Jun 1. pii: gaz027. doi: 10.1093/molehr/gaz027. [Epub ahead of print].

Possible cooption of a VEGF-driven tubulogenesis program for biomineralization in echinoderms

Authors:
Morgulis M, Gildor T, Roopin M, Sher N, Malik A, Lalzar M, Dines M, Ben-Tabou de-Leon S, Khalaily L, Ben-Tabou de-Leon S
Citation:
Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12353-12362. doi: 10.1073/pnas.1902126116. Epub 2019 May 31. PMID: 31152134; PMCID: PMC6589685
Epub:
Yes
Abstract:
Biomineralization is the process by which living organisms use minerals to form hard structures that protect and support them....
Link:
https://www.pnas.org/doi/full/10.1073/pnas.1902126116
Delivery Method:
microinjection
Organism or Cell Type:
Paracentrotus lividus (sea urchin)
Citation Extract:
Morgulis M, Gildor T, Roopin M, Sher N, Malik A, Lalzar M, Dines M, Ben-Tabou de-Leon S, Khalaily L, Ben-Tabou de-Leon S. Possible cooption of a VEGF-driven tubulogenesis program for biomineralization in echinoderms. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12353-12362. doi: 10.1073/pnas.1902126116. Epub 2019 May 31. PMID: 31152134; PMCID: PMC6589685.

Cytochrome P450 26A1 modulates uterine dendritic cells in mice early pregnancy

Authors:
Gu AQ, Li DD, Wei DP, Liu YQ, Ji WH, Yang Y, Lin HY, Peng JP
Citation:
J Cell Mol Med. 2019 May 31. doi: 10.1111/jcmm.14423. [Epub ahead of print]
Epub:
Yes
Abstract:
Cytochrome P450 26A1 (CYP26A1) plays important roles in the mice peri-implantation period. Inhibiting its expression or...
Link:
https://onlinelibrary.wiley.com/doi/full/10.1111/jcmm.14423
Delivery Method:
intrauterine injection
Organism or Cell Type:
mice
Citation Extract:
Gu AQ, Li DD, Wei DP, Liu YQ, Ji WH, Yang Y, Lin HY, Peng JP. Cytochrome P450 26A1 modulates uterine dendritic cells in mice early pregnancy. J Cell Mol Med. 2019 May 31. doi: 10.1111/jcmm.14423. [Epub ahead of print].

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