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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Zebrafish Wtx is a negative regulator of Wnt signaling but is dispensable for embryonic development and organ homeostasis

Authors:
Große A, Perner B, Naumann U, Englert C
Citation:
Dev Dyn. 2019 Jul 10. doi: 10.1002/dvdy.84. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: The X-chromosomally linked gene WTX is a human disease gene and a member of the AMER family. Mutations in WTX are...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1002/dvdy.84
Organism or Cell Type:
zebrafish
Citation Extract:
Große A, Perner B, Naumann U, Englert C. Zebrafish Wtx is a negative regulator of Wnt signaling but is dispensable for embryonic development and organ homeostasis. Dev Dyn. 2019 Jul 10. doi: 10.1002/dvdy.84. [Epub ahead of print].

High-throughput analysis reveals novel maternal germline RNAs crucial for primordial germ cell preservation and proper migration

Authors:
Owens DA, Butler AM, Aguero TH, Newman KM, Van Booven D, King ML
Citation:
Development. 2017 Jan 15;144(2):292-304. doi: 10.1242/dev.139220
Epub:
Not Epub
Abstract:
During oogenesis, hundreds of maternal RNAs are selectively localized to the animal or vegetal pole, including determinants of...
Link:
https://dev.biologists.org/content/144/2/292.long
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Owens DA, Butler AM, Aguero TH, Newman KM, Van Booven D, King ML. High-throughput analysis reveals novel maternal germline RNAs crucial for primordial germ cell preservation and proper migration. Development. 2017 Jan 15;144(2):292-304. doi: 10.1242/dev.139220.

Myelin degeneration induced by mutant superoxide dismutase 1 accumulation promotes amyotrophic lateral sclerosis

Authors:
Kim S, Chung A-H, Na JE, Lee SJ, Jeong SH, Kim E, Sun W, Rhyu IJ, Park H-C
Citation:
Glia. 2019;[Epub ahead of print] doi:10.1002/glia.23669
Epub:
Yes
Abstract:
Myelin is a specialized membrane that wraps around nerve fibers and is essential for normal axonal conduction in neurons. In...
Link:
https://onlinelibrary.wiley.com/doi/full/10.1002/glia.23669
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim S, Chung A-H, Na JE, Lee SJ, Jeong SH, Kim E, Sun W, Rhyu IJ, Park H-C. Myelin degeneration induced by mutant superoxide dismutase 1 accumulation promotes amyotrophic lateral sclerosis. Glia. 2019;[Epub ahead of print] doi:10.1002/glia.23669.

Tfap2a is a novel gatekeeper of nephron differentiation during kidney development

Authors:
Chambers BE, Gerlach GF, Clark EG, Chen KH, Levesque AE, Leshchiner I, Goessling W, Wingert RA
Citation:
Development. 2019 Jun 3. pii: dev.172387. doi: 10.1242/dev.172387. [Epub ahead of print]
Epub:
Yes
Abstract:
Renal functional units known as nephrons undergo patterning events during development that create a segmental array of cellular...
Link:
https://dev.biologists.org/content/146/13/dev172387
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chambers BE, Gerlach GF, Clark EG, Chen KH, Levesque AE, Leshchiner I, Goessling W, Wingert RA. Tfap2a is a novel gatekeeper of nephron differentiation during kidney development. Development. 2019 Jun 3. pii: dev.172387. doi: 10.1242/dev.172387. [Epub ahead of print].

Notch-mediated inhibition of neurogenesis is required for zebrafish spinal cord morphogenesis

Authors:
Sharma P, Saraswathy VM, Xiang L, Fürthauer M
Citation:
Sci Rep. 2019;9(1):9958. doi:10.1038/s41598-019-46067-1
Epub:
Not Epub
Abstract:
The morphogenesis of the nervous system requires coordinating the specification and differentiation of neural precursor cells,...
Link:
https://www.nature.com/articles/s41598-019-46067-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sharma P, Saraswathy VM, Xiang L, Fürthauer M. Notch-mediated inhibition of neurogenesis is required for zebrafish spinal cord morphogenesis. Sci Rep. 2019;9(1):9958. doi:10.1038/s41598-019-46067-1.

Heroin Cue-Evoked Astrocytic Structural Plasticity at Nucleus Accumbens Synapses Inhibits Heroin Seeking

Authors:
Kruyer A, Scofield MD, Wood D, Reissner KJ, Kalivas PW
Citation:
Biol Psychiatry. 2019 Jul 8. pii: S0006-3223(19)31508-2. doi: 10.1016/j.biopsych.2019.06.026. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Background: Opioid addiction is a critical medical and social problem characterized by vulnerability to relapse. Glutamatergic...
Link:
https://www.sciencedirect.com/science/article/pii/S0006322319315082
Delivery Method:
bilateral NAcore brain infusion Vivo-Morpholino
Organism or Cell Type:
Rats Sprague-Dawley male
Citation Extract:
Kruyer A, Scofield MD, Wood D, Reissner KJ, Kalivas PW. Heroin Cue-Evoked Astrocytic Structural Plasticity at Nucleus Accumbens Synapses Inhibits Heroin Seeking. Biol Psychiatry. 2019 Jul 8. pii: S0006-3223(19)31508-2. doi: 10.1016/j.biopsych.2019.06.026. [Epub ahead of print].

The role of maternal pioneer factors in predefining first zygotic responses to inductive signals

Authors:
Gentsch GE, Spruce T, Owens NDL, Smith JC
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/306803
Epub:
Not Epub
Abstract:
Embryonic development yields many different cell types in response to just a few families of inductive signals. The property of...
Link:
https://www.biorxiv.org/content/10.1101/306803v3
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Gentsch GE, Spruce T, Owens NDL, Smith JC. The role of maternal pioneer factors in predefining first zygotic responses to inductive signals. bioRxiv. 2019;[preprint] doi:10.1101/306803 .

The lncRNAs Implicated in Redox Regulation in Ybx1 Deficient Zebrafish Larvae

Authors:
Huang C, Zhu B, Leng D, Ge W, Zhang XD
Citation:
bioRxiv. 2019;[preprint] doi:/10.1101/679167
Epub:
Not Epub
Abstract:
Ybx1 has been demonstrated as a crucial gene in embryogenesis, reproduction as well as development in various vertebrates such...
Link:
https://www.biorxiv.org/content/10.1101/679167v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huang C, Zhu B, Leng D, Ge W, Zhang XD. The lncRNAs Implicated in Redox Regulation in Ybx1 Deficient Zebrafish Larvae. bioRxiv. 2019;[preprint] doi:/10.1101/679167.

Cell and tissue morphology determine actin-dependent nuclear migration mechanisms in neuroepithelia

Authors:
Yanakieva I, Erzberger A, Matejčić M, Modes CD, Norden C
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/536698
Epub:
Not Epub
Abstract:
Correct nuclear position is crucial for cellular function and tissue development. Depending on cell context however,...
Link:
https://www.biorxiv.org/content/10.1101/536698v2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yanakieva I, Erzberger A, Matejčić M, Modes CD, Norden C. Cell and tissue morphology determine actin-dependent nuclear migration mechanisms in neuroepithelia. bioRxiv. 2019;[preprint] doi:10.1101/536698 .

Actomyosin regulation by Eph receptor signaling couples boundary cell formation to border sharpness

Authors:
Cayuso J, Xu Q, Addison M, Wilkinson DG
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/683631
Epub:
Not Epub
Abstract:
The segregation of cells with distinct regional identity underlies formation of a sharp border, which in some tissues serves to...
Link:
https://www.biorxiv.org/content/10.1101/683631v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cayuso J, Xu Q, Addison M, Wilkinson DG. Actomyosin regulation by Eph receptor signaling couples boundary cell formation to border sharpness. bioRxiv. 2019;[preprint] doi:10.1101/683631 .

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