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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Intracellular enhancement of BMP signaling by LIM-domain protein FHL3 controls spatiotemporal emergence of the neural crest driven by WNT signaling

Authors:
Alkobtawi M, Pla P, Monsoro-Burq AH
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/711192
Epub:
Not Epub
Abstract:
How multiple morphogen signals are coordinated in space and time to position key embryonic tissues remains elusive. During...
Link:
https://www.biorxiv.org/content/10.1101/711192v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Alkobtawi M, Pla P, Monsoro-Burq AH. Intracellular enhancement of BMP signaling by LIM-domain protein FHL3 controls spatiotemporal emergence of the neural crest driven by WNT signaling. bioRxiv. 2019;[preprint] doi:10.1101/711192.

Deficiency in the endocytic adaptor protein PHETA1/2 impairs renal and craniofacial development

Authors:
Ates KM, Wang T, Moreland T, Veeranan-Karmegam R, Anand P, Wenzel W, Kim H-G, Wolfe LA, Stephen JA, Adams DR, Markello T, Tifft CJ, Gahl WA, Gonsalvez GB, May Christine Malicdan, Flanagan-Steet H, Pan Y
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/727578
Epub:
Not Epub
Abstract:
A critical barrier in the treatment of endosomal and lysosomal diseases is the lack of understanding of the in vivo functions...
Link:
https://www.biorxiv.org/content/10.1101/727578v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ates KM, Wang T, Moreland T, Veeranan-Karmegam R, Anand P, Wenzel W, Kim H-G, Wolfe LA, Stephen JA, Adams DR, Markello T, Tifft CJ, Gahl WA, Gonsalvez GB, May Christine Malicdan, Flanagan-Steet H, Pan Y. Deficiency in the endocytic adaptor protein PHETA1/2 impairs renal and craniofacial development. bioRxiv. 2019;[preprint] doi:10.1101/727578.

NAD+ improves neuromuscular development in a zebrafish model of FKRP-associated dystroglycanopathy

Authors:
Bailey EC, Alrowaished SS, Kilroy EA, Crooks ES, Drinkert DM, Karunasiri CM, Belanger JJ, Khalil A, Kelley JB, Henry CA
Citation:
Skeletal Musc. 2019;9:21. doi:10.1186/s13395-019-0206-1
Epub:
Not Epub
Abstract:
Background: Secondary dystroglycanopathies are muscular dystrophies that result from mutations in genes that participate in...
Link:
https://link.springer.com/article/10.1186%2Fs13395-019-0206-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bailey EC, Alrowaished SS, Kilroy EA, Crooks ES, Drinkert DM, Karunasiri CM, Belanger JJ, Khalil A, Kelley JB, Henry CA. NAD+ improves neuromuscular development in a zebrafish model of FKRP-associated dystroglycanopathy. Skeletal Musc. 2019;9:21. doi:10.1186/s13395-019-0206-1.

Akap12beta supports asymmetric heart development via modulating the Kupffer's vesicle formation in zebrafish

Authors:
Kim JG, Kim HH, Bae SJ
Citation:
BMB Rep. 2019 Aug 6. pii: 4619. [Epub ahead of print]
Epub:
Yes
Abstract:
The vertebrate body plan is accomplished by left-right asymmetric organ development and the heart is a representative...
Link:
http://submit.bmbreports.org/Search/View.html?tmp_tr_num=4619
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim JG, Kim HH, Bae SJ. Akap12beta supports asymmetric heart development via modulating the Kupffer's vesicle formation in zebrafish. BMB Rep. 2019 Aug 6. pii: 4619. [Epub ahead of print].

RNA 5-Methylcytosine Facilitates the Maternal-to-Zygotic Transition by Preventing Maternal mRNA Decay

Authors:
Yang Y, Wang L, Han X, Yang W-L, Zhang M, Ma H-L, Sun B-F, Li A, Xia J, Chen J, Heng J, Wu B, Chen Y-S, Xu J-W, Yang X, Yao H, Sun J, Lyu C, Wang H-L, Huang Y, Sun Y-P, Zhao Y-L, Meng A, Ma J, Liu F, Yang Y-G
Citation:
Molec Cell, 2019;[Epub ahead of print] doi:10.1016/j.molcel.2019.06.033
Epub:
Yes
Abstract:
The maternal-to-zygotic transition (MZT) is a conserved and fundamental process during which the maternal environment is...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1097276519304903
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang Y, Wang L, Han X, Yang W-L, Zhang M, Ma H-L, Sun B-F, Li A, Xia J, Chen J, Heng J, Wu B, Chen Y-S, Xu J-W, Yang X, Yao H, Sun J, Lyu C, Wang H-L, Huang Y, Sun Y-P, Zhao Y-L, Meng A, Ma J, Liu F, Yang Y-G. RNA 5-Methylcytosine Facilitates the Maternal-to-Zygotic Transition by Preventing Maternal mRNA Decay. Molec Cell, 2019;[Epub ahead of print] doi:10.1016/j.molcel.2019.06.033.

Artery-vein specification in the zebrafish trunk is pre-patterned by heterogeneous Notch activity and balanced by flow-mediated fine tuning

Authors:
Geudens I, Coxam B, Alt S, Gebala V, Vion AC, Meier K, Rosa A, Gerhardt H
Citation:
Development. 2019 Aug 2. pii: dev.181024. doi: 10.1242/dev.181024. [Epub ahead of print]
Epub:
Yes
Abstract:
How developing vascular networks acquire the right balance of arteries, veins and lymphatic vessels to efficiently supply and...
Link:
https://dev.biologists.org/content/early/2019/07/31/dev.181024
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Geudens I, Coxam B, Alt S, Gebala V, Vion AC, Meier K, Rosa A, Gerhardt H. Artery-vein specification in the zebrafish trunk is pre-patterned by heterogeneous Notch activity and balanced by flow-mediated fine tuning. Development. 2019 Aug 2. pii: dev.181024. doi: 10.1242/dev.181024. [Epub ahead of print].

Loss of cell cycle control renders cells nonresponsive to local extrinsic differentiation cues

Authors:
Cerveny KL, Tower I, Lamb DB, Van Duzer A, Bronstein H, Hagen O, Varga M
Citation:
bioRxiv. 2019:[preprint] doi:10.1101/720276
Epub:
Not Epub
Abstract:
Objective and approaches: Aberrantly proliferating cells are linked to a number of diseases including cancers and developmental...
Link:
https://www.biorxiv.org/content/10.1101/720276v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cerveny KL, Tower I, Lamb DB, Van Duzer A, Bronstein H, Hagen O, Varga M. Loss of cell cycle control renders cells nonresponsive to local extrinsic differentiation cues. bioRxiv. 2019:[preprint] doi:10.1101/720276 .

Genetic and functional evidence relates a missense variant in B4GALT1 to lower LDL-C and fibrinogen

Authors:
Montasser ME, Van Hout CV, McFarland R, Rosenberg A, Callaway M, Shen B, Li N, Daly TJ, Howard AD, Lin W, Mao Y, Ye B, Gatta GD, Tzoneva G, Perry J, Ryan KA, Miloscio L, Economides AN, Regeneron Genetics Center, NHLBI TOPMed Program, Sztalryd-Woodle C, Mitchell BD, Healy M, Streeten E, Zaghloul NA, Taylor SI, O’Connell JR, Shuldiner AR
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/721704
Epub:
Not Epub
Abstract:
Increased LDL-cholesterol (LDL-C) and fibrinogen are independent risk factors for cardiovascular disease (CVD). We identified...
Link:
https://www.biorxiv.org/content/10.1101/721704v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Montasser ME, Van Hout CV, McFarland R, Rosenberg A, Callaway M, Shen B, Li N, Daly TJ, Howard AD, Lin W, Mao Y, Ye B, Gatta GD, Tzoneva G, Perry J, Ryan KA, Miloscio L, Economides AN, Regeneron Genetics Center, NHLBI TOPMed Program, Sztalryd-Woodle C, Mitchell BD, Healy M, Streeten E, Zaghloul NA, Taylor SI, O’Connell JR, Shuldiner AR. Genetic and functional evidence relates a missense variant in B4GALT1 to lower LDL-C and fibrinogen. bioRxiv. 2019;[preprint] doi:10.1101/721704.

A new transgenic reporter line reveals Wnt-dependent Snai2 re-expression and cranial neural crest differentiation in Xenopus

Authors:
Li J, Perfetto M, Materna C, Li R, Thi Tran H, Vleminckx K, Duncan MK, Wei S
Citation:
Sci Rep. 2019 Aug 1;9(1):11191. doi: 10.1038/s41598-019-47665-9
Epub:
Not Epub
Abstract:
During vertebrate embryogenesis, the cranial neural crest (CNC) forms at the neural plate border and subsequently migrates and...
Link:
https://www.nature.com/articles/s41598-019-47665-9
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Li J, Perfetto M, Materna C, Li R, Thi Tran H, Vleminckx K, Duncan MK, Wei S. A new transgenic reporter line reveals Wnt-dependent Snai2 re-expression and cranial neural crest differentiation in Xenopus. Sci Rep. 2019 Aug 1;9(1):11191. doi: 10.1038/s41598-019-47665-9.

LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis.

Authors:
Morishima T, Krahl AC, Nasri M, Xu Y, Aghaallaei N, Findik B, Klimiankou M, Ritter M, Hartmann MD, Gloeckner CJ, Stefańczyk S, Lindner C, Oswald B, Bernhard R, Hähnel K, Hermanutz-Klein U, Ebinger M, Handgretinger R, Casadei N, Welte K, Andre M, Müller P, Bajoghli B, Skokowa J
Citation:
Blood. 2019 Jul 31. pii: blood 2019000095. doi: 10.1182/blood.2019000095. [Epub ahead of print]
Epub:
Yes
Abstract:
LMO2 (hematopoietic transcription factor LIM domain only 2), a member of the TAL1 transcriptional complex, plays an essential...
Link:
http://www.bloodjournal.org/content/early/2019/07/31/blood.2019000095
Organism or Cell Type:
zebrafish
Citation Extract:
Morishima T, Krahl AC, Nasri M, Xu Y, Aghaallaei N, Findik B, Klimiankou M, Ritter M, Hartmann MD, Gloeckner CJ, Stefańczyk S, Lindner C, Oswald B, Bernhard R, Hähnel K, Hermanutz-Klein U, Ebinger M, Handgretinger R, Casadei N, Welte K, Andre M, Müller P, Bajoghli B, Skokowa J. LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis. . Blood. 2019 Jul 31. pii: blood 2019000095. doi: 10.1182/blood.2019000095. [Epub ahead of print].

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