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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12158 scientific papers returned from the database with the search filters currently being used below.

STIM1 Is Required for Remodeling of the Endoplasmic Reticulum and Microtubule Cytoskeleton in Steering Growth Cones

Authors:
Pavez M, Thompson AC, Arnott HJ, Mitchell CB, D'Atri I, Don EK, Chilton JK, Scott EK, Lin JY, Young KM, Gasperini RJ, Foa L
Citation:
J Neurosci. 2019 Jun 26;39(26):5095-5114. doi: 10.1523/JNEUROSCI.2496-18.2019. Epub 2019 Apr 25
Epub:
Not Epub
Abstract:
The spatial and temporal regulation of calcium signaling in neuronal growth cones is essential for axon guidance. In growth...
Citation Extract:
Pavez M, Thompson AC, Arnott HJ, Mitchell CB, D'Atri I, Don EK, Chilton JK, Scott EK, Lin JY, Young KM, Gasperini RJ, Foa L. STIM1 Is Required for Remodeling of the Endoplasmic Reticulum and Microtubule Cytoskeleton in Steering Growth Cones. J Neurosci. 2019 Jun 26;39(26):5095-5114. doi: 10.1523/JNEUROSCI.2496-18.2019. Epub 2019 Apr 25.

The Xenopus Nieuwkoop center and Spemann-Mangold organizer share molecular components and a requirement for maternal Wnt activity

Authors:
Vonica A, Gumbiner BM
Citation:
Dev Biol. 2007 Dec 1;312(1):90-102. Epub 2007 Oct 2
Epub:
Not Epub
Abstract:
In Xenopus embryos, the dorso-ventral and antero-posterior axes are established by the Spemann-Mangold organizer. According to...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Vonica A, Gumbiner BM. The Xenopus Nieuwkoop center and Spemann-Mangold organizer share molecular components and a requirement for maternal Wnt activity. Dev Biol. 2007 Dec 1;312(1):90-102. Epub 2007 Oct 2.

Global analysis of polysome-associated mRNA in vesicular stomatitis virus infected cells

Authors:
Neidermyer WJ Jr, Whelan SPJ
Citation:
PLoS Pathog. 2019;15(6):e1007875. doi:10.1371/journal.ppat.1007875
Epub:
Not Epub
Abstract:
Infection of mammalian cells with vesicular stomatitis virus (VSV) results in the inhibition of cellular translation while...
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Neidermyer WJ Jr, Whelan SPJ. Global analysis of polysome-associated mRNA in vesicular stomatitis virus infected cells. PLoS Pathog. 2019;15(6):e1007875. doi:10.1371/journal.ppat.1007875.

Hypothalamic nesfatin-1 mediates feeding behavior via MC3/4R-ERK signaling pathway after weight loss in obese Sprague-Dawley rats

Authors:
Wang Y
Citation:
Peptides. 2019 Jun 28. pii: S0196-9781(19)30038-5. doi: 10.1016/j.peptides.2019.04.007. [Epub ahead of print]
Epub:
Yes
Abstract:
Nesfatin-1 is an anorexic peptide derived from nucleobindin 2 (NUCB2). An increase in hypothalamic nesfatin-1 inhibits feeding...
Delivery Method:
intracerebroventricular infusion
Organism or Cell Type:
rats
Citation Extract:
Wang Y. Hypothalamic nesfatin-1 mediates feeding behavior via MC3/4R-ERK signaling pathway after weight loss in obese Sprague-Dawley rats. Peptides. 2019 Jun 28. pii: S0196-9781(19)30038-5. doi: 10.1016/j.peptides.2019.04.007. [Epub ahead of print].

Glucocorticoid receptor-dependent induction of cripto-1 (one-eyed pinhead) inhibits zebrafish caudal fin regeneration

Authors:
Garland MA, Sengupta S, Mathew LK, Truong L, de Jong E, Piersma AH, La Du J, Tanguay RL
Citation:
Toxicol Rep. 2019 May 29;6:529-537. doi: 10.1016/j.toxrep.2019.05.013. eCollection 2019
Epub:
Not Epub
Abstract:
We previously used a chemical genetics approach with the larval zebrafish to identify small molecule inhibitors of tissue...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Garland MA, Sengupta S, Mathew LK, Truong L, de Jong E, Piersma AH, La Du J, Tanguay RL. Glucocorticoid receptor-dependent induction of cripto-1 (one-eyed pinhead) inhibits zebrafish caudal fin regeneration. Toxicol Rep. 2019 May 29;6:529-537. doi: 10.1016/j.toxrep.2019.05.013. eCollection 2019.

Dual roles of hydrogen peroxide in promoting zebrafish renal repair and regeneration

Authors:
Chen J, Yu T, He X, Fu Y, Dai L, Wang B, Wu Y, He J, Li Y, Zhang F, Zhao J, Liu C
Citation:
Biochem Biophys Res Commun. 2019 Jun 24. pii: S0006-291X(19)31178-7. doi: 10.1016/j.bbrc.2019.06.052. [Epub ahead of print]
Epub:
Yes
Abstract:
Acute renal injury (AKI) is a serious disorder of renal failure or renal damage that occurs within hours or days. At present,...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Chen J, Yu T, He X, Fu Y, Dai L, Wang B, Wu Y, He J, Li Y, Zhang F, Zhao J, Liu C. Dual roles of hydrogen peroxide in promoting zebrafish renal repair and regeneration. Biochem Biophys Res Commun. 2019 Jun 24. pii: S0006-291X(19)31178-7. doi: 10.1016/j.bbrc.2019.06.052. [Epub ahead of print].

Pax2a regulates angiogenesis to facilitate fusion of the optic fissure

Authors:
Weaver ML, Piedade WP, Meshram NN, Famulski JK
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/678185
Epub:
Not Epub
Abstract:
Formation of the vertebrate retina involves timely and precise fusion of the optic fissure, failure of which results in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weaver ML, Piedade WP, Meshram NN, Famulski JK. Pax2a regulates angiogenesis to facilitate fusion of the optic fissure. bioRxiv. 2019;[preprint] doi:10.1101/678185.

The combination of loss of glyoxalase1 and obesity results in hyperglycemia

Authors:
Lodd E, Wiggenhauser LM, Morgenstern J, Fleming TH, Poschet G, Büttner M, Tabler CT, Wohlfart DP, Nawroth PP, Kroll J
Citation:
JCI Insight. 2019 Jun 20;4(12). pii: 126154. doi: 10.1172/jci.insight.126154. eCollection 2019 Jun 20
Epub:
Not Epub
Abstract:
The increased formation of methylglyoxal (MG) under hyperglycemia is associated with the development of microvascular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lodd E, Wiggenhauser LM, Morgenstern J, Fleming TH, Poschet G, Büttner M, Tabler CT, Wohlfart DP, Nawroth PP, Kroll J. The combination of loss of glyoxalase1 and obesity results in hyperglycemia. JCI Insight. 2019 Jun 20;4(12). pii: 126154. doi: 10.1172/jci.insight.126154. eCollection 2019 Jun 20.

Connexin 43 impacts the chick premigratory cranial neural crest cell population without affecting the neural crest cell epithelial-to-mesenchymal transition

Authors:
Jourdeuil K, Taneyhill LA
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/673921
Epub:
Not Epub
Abstract:
Gap junctions are intercellular channels that allow for the diffusion of small ions and solutes between coupled cells. Connexin...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Jourdeuil K, Taneyhill LA. Connexin 43 impacts the chick premigratory cranial neural crest cell population without affecting the neural crest cell epithelial-to-mesenchymal transition. bioRxiv. 2019;[preprint] doi:10.1101/673921 .

Direct Reprogramming of Human DMD Fibroblasts into Myotubes for In Vitro Evaluation of Antisense-Mediated Exon Skipping and Exons 45-55 Skipping Accompanied by Rescue of Dystrophin Expression

Authors:
Lee JJA, Saito T, Duddy W, Takeda S, Yokota T
Citation:
Methods Mol Biol. 2018;1828:141-150. doi: 10.1007/978-1-4939-8651-4_8
Epub:
Not Epub
Abstract:
Antisense oligonucleotide-mediated exon skipping is a promising therapeutic approach for the treatment of various genetic...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: primary human fibroblasts (DMD)
Citation Extract:
Lee JJA, Saito T, Duddy W, Takeda S, Yokota T. Direct Reprogramming of Human DMD Fibroblasts into Myotubes for In Vitro Evaluation of Antisense-Mediated Exon Skipping and Exons 45-55 Skipping Accompanied by Rescue of Dystrophin Expression. Methods Mol Biol. 2018;1828:141-150. doi: 10.1007/978-1-4939-8651-4_8.

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