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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
A conserved regulatory program initiates lateral plate mesoderm emergence across chordates
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Citation:
Nat Comm. 2019;10(1):3857. doi:10.1038/s41467-019-11561-7 Epub:
Not Epub Abstract:
Cardiovascular lineages develop together with kidney, smooth muscle, and limb connective tissue progenitors from the lateral... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Prummel KD, Hess C, Nieuwenhuize S, Parker HJ, Rogers KW, Kozmikova I, Racioppi C, Brombacher EC, Anna Czarkwiani, Knapp D, Burger S, Chiavacci E, Shah G, Burger A, Huisken J, Yun MH, Christiaen L, Kozmik Z, Müller P, Bronner M, Krumlauf R, Mosimann C. A conserved regulatory program initiates lateral plate mesoderm emergence across chordates. Nat Comm. 2019;10(1):3857. doi:10.1038/s41467-019-11561-7. |
Microsyntenic Clusters Reveal Conservation of lncRNAs in Chordates Despite Absence of Sequence Conservation
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Citation:
Biology. 2019;8(3):61. doi:10.3390/biology8030061 Epub:
Not Epub Abstract:
Homologous long non-coding RNAs (lncRNAs) are elusive to identify by sequence similarity due to their fast-evolutionary rate.... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Herrera-Úbeda C, Marín-Barba M, Navas-Pérez E, Gravemeyer J, Albuixech-Crespo BA, Wheeler GN, Garcia-Fernàndez J. Microsyntenic Clusters Reveal Conservation of lncRNAs in Chordates Despite Absence of Sequence Conservation. Biology. 2019;8(3):61. doi:10.3390/biology8030061. |
Functional role of pax6 during eye and nervous system development in the annelid Capitella teleta
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Citation:
Dev Biol. 2019 Aug 21. pii: S0012-1606(18)30055-1. doi: 10.1016/j.ydbio.2019.08.011. [Epub ahead of print] Epub:
Yes Abstract:
The transcription factor Pax6 is an important regulator of early animal development. Loss of function mutations of pax6 in a... Delivery Method:
microinjection Organism or Cell Type:
Capitella teleta (annelid) Citation Extract: Klann M, Seaver EC. Functional role of pax6 during eye and nervous system development in the annelid Capitella teleta. Dev Biol. 2019 Aug 21. pii: S0012-1606(18)30055-1. doi: 10.1016/j.ydbio.2019.08.011. [Epub ahead of print]. |
Failure to clear developmental apoptosis contributes to the pathology of RNASET2-deficient leukoencephalopathy
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/744144 Epub:
Not Epub Abstract:
The contribution of microglia in neurological disorders is emerging as a leading driver rather than a consequence of pathology... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hamilton N, Rutherford HA, Isles HM, Petts JJ, Henneke M, Gaertner J, Dunning M, Renshaw SA. Failure to clear developmental apoptosis contributes to the pathology of RNASET2-deficient leukoencephalopathy. bioRxiv. 2019;[preprint] doi:10.1101/744144. |
Chemokine signaling links cell-cycle progression and cilia formation for left–right symmetry breaking
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Citation:
PLoS Biol. 2019;17(8):e3000203. doi:10.1371/journal.pbio.3000203 Epub:
Not Epub Abstract:
Zebrafish dorsal forerunner cells (DFCs) undergo vigorous proliferation during epiboly and then exit the cell cycle to generate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu J, Zhu C, Ning G, Yang L, Cao Y, Huang S, Wang Q. Chemokine signaling links cell-cycle progression and cilia formation for left–right symmetry breaking. PLoS Biol. 2019;17(8):e3000203. doi:10.1371/journal.pbio.3000203. |
Genome-wide identification of binding sites and gene targets of Alx1, a pivotal regulator of echinoderm skeletogenesis
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Citation:
Development. 2019;146:dev180653. doi: 10.1242/dev.180653 Epub:
Not Epub Abstract:
Alx1 is a conserved regulator of skeletogenesis in echinoderms and evolutionary changes in Alx1 sequence and expression have... Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Khor JM, Guerrero-Santoro J, Ettensohn CA. Genome-wide identification of binding sites and gene targets of Alx1, a pivotal regulator of echinoderm skeletogenesis. Development. 2019;146:dev180653. doi: 10.1242/dev.180653. |
Evolutionary modification of AGS protein contributes to formation of micromeres in sea urchins
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Citation:
Nat Comm. 2019;10(1):3779. doi:10.1038/s41467-019-11560-8 Epub:
Not Epub Abstract:
Evolution is proposed to result, in part, from acquisition of new developmental programs. One such example is the appearance of... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Poon J, Fries A, Wessel GM, Yajima M. Evolutionary modification of AGS protein contributes to formation of micromeres in sea urchins. Nat Comm. 2019;10(1):3779. doi:10.1038/s41467-019-11560-8. |
Rab35 controls cilium length, function and membrane composition
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Citation:
EMBO Rep. 2019 Aug 21:e47625. doi: 10.15252/embr.201847625. [Epub ahead of print] Epub:
Not Epub Abstract:
Rab and Arl guanine nucleotide-binding (G) proteins regulate trafficking pathways essential for the formation, function and... Organism or Cell Type:
zebrafish Citation Extract: Kuhns S, Seixas C, Pestana S, Tavares B, Nogueira R, Jacinto R, Ramalho JS, Simpson JC, Andersen JS, Echard A, Lopes SS, Barral DC, Blacque OE. Rab35 controls cilium length, function and membrane composition. EMBO Rep. 2019 Aug 21:e47625. doi: 10.15252/embr.201847625. [Epub ahead of print]. |
Sulfatases, in Particular Sulf1, Are Important for the Integrity of the Glomerular Filtration Barrier in Zebrafish
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Citation:
Biomed Res Int. 2019 Jul 22;2019:4508048. doi: 10.1155/2019/4508048. eCollection 2019 Epub:
Not Epub Abstract:
The 6-O-endosulfatases (sulfs) are important enzymatic components involved in the regulation of heparan sulfate by altering the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Schenk H, Masseli A, Schroder P, Bolaños-Palmieri P, Beese M, Hegermann J, Bräsen JH, Haller H. Sulfatases, in Particular Sulf1, Are Important for the Integrity of the Glomerular Filtration Barrier in Zebrafish. Biomed Res Int. 2019 Jul 22;2019:4508048. doi: 10.1155/2019/4508048. eCollection 2019. |
Nicastrin Deficiency Induces Tyrosinase-dependent Depigmentation and Skin Inflammation
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Citation:
J Invest Dermatol. 2019;[Epub ahead of print] doi:10.1016/j.jid.2019.07.702 Epub:
Not Epub Abstract:
Skin depigmentation diseases, such as vitiligo, are pigmentation disorders that often destroy melanocytes. However, their... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hsu C-h, Liou G-G, Jiang Y-J. Nicastrin Deficiency Induces Tyrosinase-dependent Depigmentation and Skin Inflammation. J Invest Dermatol. 2019;[Epub ahead of print] doi:10.1016/j.jid.2019.07.702. |