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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12152 scientific papers returned from the database with the search filters currently being used below.

Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium

Authors:
Bonkhofer F, Rispoli R, Pinheiro P, Krecsmarik M, Schneider-Swales J, Tsang IHC, de Bruijn M, Monteiro R, Peterkin T, Patient R
Citation:
Nat Comm. 2019;10(1):3577. doi:10.1038/s41467-019-11423-2
Epub:
Not Epub
Abstract:
Haematopoietic stem cells are generated from the haemogenic endothelium (HE) located in the floor of the dorsal aorta (DA)....
Link:
https://www.nature.com/articles/s41467-019-11423-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bonkhofer F, Rispoli R, Pinheiro P, Krecsmarik M, Schneider-Swales J, Tsang IHC, de Bruijn M, Monteiro R, Peterkin T, Patient R. Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium. Nat Comm. 2019;10(1):3577. doi:10.1038/s41467-019-11423-2.

TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes

Authors:
Limburg H, Harbig A, Bestle D, Stein DA, Moulton HM, Jaeger J, Janga H, Hardes K, Koepke J, Schulte L, Koczulla AR, Schmeck B, Klenk HD, Böttcher-Friebertshäuser E
Citation:
J Virol. 2019 Oct 15;93(21):e00649-19. doi: 10.1128/JVI.00649-19. PMID: 31391268; PMCID: PMC6803253
Epub:
Yes
Abstract:
Cleavage of influenza virus hemagglutinin (HA) by host cell proteases is essential for virus infectivity and spread. We...
Link:
https://journals.asm.org/doi/10.1128/jvi.00649-19
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: primary human bronchial epithelial cells (HBEC), primary type II alveolar epithelial cells (AECII) and Calu-3 cells
Citation Extract:
Limburg H, Harbig A, Bestle D, Stein DA, Moulton HM, Jaeger J, Janga H, Hardes K, Koepke J, Schulte L, Koczulla AR, Schmeck B, Klenk HD, Böttcher-Friebertshäuser E. TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes. J Virol. 2019 Oct 15;93(21):e00649-19. doi: 10.1128/JVI.00649-19. PMID: 31391268; PMCID: PMC6803253.

Zebrafish Dynamin is required for maintenance of enveloping layer integrity and the progression of epiboly

Authors:
Lepage SE, Tada M, Bruce AE
Citation:
Dev Biol. 2014 Jan 1;385(1):52-66. doi: 10.1016/j.ydbio.2013.10.015. Epub 2013 Oct 24
Epub:
Not Epub
Abstract:
Epiboly, the first morphogenetic cell movement that occurs in the zebrafish embryo, is the process by which the blastoderm...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160613005599
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lepage SE, Tada M, Bruce AE. Zebrafish Dynamin is required for maintenance of enveloping layer integrity and the progression of epiboly. Dev Biol. 2014 Jan 1;385(1):52-66. doi: 10.1016/j.ydbio.2013.10.015. Epub 2013 Oct 24.

Planar polarization of cilia in the zebrafish floor-plate involves Par3-mediated posterior localization of highly motile basal bodies

Authors:
Donati A, Anselme I, Schneider-Maunoury S, Vesque C
Citation:
Development. 2021 Jul 1;148(13):dev196386. doi: 10.1242/dev.196386. Epub 2021 Jul 8. PMID: 34104942
Epub:
Not Epub
Abstract:
Epithelial cilia, whether motile or primary, often display an off-center planar localization within the apical cell surface....
Link:
https://journals.biologists.com/dev/article/148/13/dev196386/270846/Planar-polarization-of-cilia-in-the-zebrafish
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Donati A, Anselme I, Schneider-Maunoury S, Vesque C. Planar polarization of cilia in the zebrafish floor-plate involves Par3-mediated posterior localization of highly motile basal bodies. Development. 2021 Jul 1;148(13):dev196386. doi: 10.1242/dev.196386. Epub 2021 Jul 8. PMID: 34104942.

BMP signaling is enhanced intracellularly by FHL3 controlling WNT-dependent spatiotemporal emergence of the neural crest

Authors:
Alkobtawi M, Pla P, Monsoro-Burq AH
Citation:
Cell Rep. 2021 Jun 22;35(12):109289. doi: 10.1016/j.celrep.2021.109289. PMID: 34161771
Epub:
Not Epub
Abstract:
The spatiotemporal coordination of multiple morphogens is essential for embryonic patterning yet poorly understood. During...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(21)00660-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Alkobtawi M, Pla P, Monsoro-Burq AH. BMP signaling is enhanced intracellularly by FHL3 controlling WNT-dependent spatiotemporal emergence of the neural crest. Cell Rep. 2021 Jun 22;35(12):109289. doi: 10.1016/j.celrep.2021.109289. PMID: 34161771.

NAD+ improves neuromuscular development in a zebrafish model of FKRP-associated dystroglycanopathy

Authors:
Bailey EC, Alrowaished SS, Kilroy EA, Crooks ES, Drinkert DM, Karunasiri CM, Belanger JJ, Khalil A, Kelley JB, Henry CA
Citation:
Skeletal Musc. 2019;9:21. doi:10.1186/s13395-019-0206-1
Epub:
Not Epub
Abstract:
Background: Secondary dystroglycanopathies are muscular dystrophies that result from mutations in genes that participate in...
Link:
https://link.springer.com/article/10.1186%2Fs13395-019-0206-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bailey EC, Alrowaished SS, Kilroy EA, Crooks ES, Drinkert DM, Karunasiri CM, Belanger JJ, Khalil A, Kelley JB, Henry CA. NAD+ improves neuromuscular development in a zebrafish model of FKRP-associated dystroglycanopathy. Skeletal Musc. 2019;9:21. doi:10.1186/s13395-019-0206-1.

Akap12beta supports asymmetric heart development via modulating the Kupffer's vesicle formation in zebrafish

Authors:
Kim JG, Kim HH, Bae SJ
Citation:
BMB Rep. 2019 Aug 6. pii: 4619. [Epub ahead of print]
Epub:
Yes
Abstract:
The vertebrate body plan is accomplished by left-right asymmetric organ development and the heart is a representative...
Link:
http://submit.bmbreports.org/Search/View.html?tmp_tr_num=4619
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim JG, Kim HH, Bae SJ. Akap12beta supports asymmetric heart development via modulating the Kupffer's vesicle formation in zebrafish. BMB Rep. 2019 Aug 6. pii: 4619. [Epub ahead of print].

RNA 5-Methylcytosine Facilitates the Maternal-to-Zygotic Transition by Preventing Maternal mRNA Decay

Authors:
Yang Y, Wang L, Han X, Yang W-L, Zhang M, Ma H-L, Sun B-F, Li A, Xia J, Chen J, Heng J, Wu B, Chen Y-S, Xu J-W, Yang X, Yao H, Sun J, Lyu C, Wang H-L, Huang Y, Sun Y-P, Zhao Y-L, Meng A, Ma J, Liu F, Yang Y-G
Citation:
Molec Cell, 2019;[Epub ahead of print] doi:10.1016/j.molcel.2019.06.033
Epub:
Yes
Abstract:
The maternal-to-zygotic transition (MZT) is a conserved and fundamental process during which the maternal environment is...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1097276519304903
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang Y, Wang L, Han X, Yang W-L, Zhang M, Ma H-L, Sun B-F, Li A, Xia J, Chen J, Heng J, Wu B, Chen Y-S, Xu J-W, Yang X, Yao H, Sun J, Lyu C, Wang H-L, Huang Y, Sun Y-P, Zhao Y-L, Meng A, Ma J, Liu F, Yang Y-G. RNA 5-Methylcytosine Facilitates the Maternal-to-Zygotic Transition by Preventing Maternal mRNA Decay. Molec Cell, 2019;[Epub ahead of print] doi:10.1016/j.molcel.2019.06.033.

Artery-vein specification in the zebrafish trunk is pre-patterned by heterogeneous Notch activity and balanced by flow-mediated fine tuning

Authors:
Geudens I, Coxam B, Alt S, Gebala V, Vion AC, Meier K, Rosa A, Gerhardt H
Citation:
Development. 2019 Aug 2. pii: dev.181024. doi: 10.1242/dev.181024. [Epub ahead of print]
Epub:
Yes
Abstract:
How developing vascular networks acquire the right balance of arteries, veins and lymphatic vessels to efficiently supply and...
Link:
https://dev.biologists.org/content/early/2019/07/31/dev.181024
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Geudens I, Coxam B, Alt S, Gebala V, Vion AC, Meier K, Rosa A, Gerhardt H. Artery-vein specification in the zebrafish trunk is pre-patterned by heterogeneous Notch activity and balanced by flow-mediated fine tuning. Development. 2019 Aug 2. pii: dev.181024. doi: 10.1242/dev.181024. [Epub ahead of print].

Genetic and functional evidence links a missense variant in B4GALT1 to lower LDL and fibrinogen

Authors:
Montasser ME, Van Hout CV, Miloscio L, Howard AD, Rosenberg A, Callaway M, Shen B, Li N, Locke AE, Verweij N, De T, Ferreira MA, Lotta LA, Baras A, Daly TJ, Hartford SA, Lin W, Mao Y, Ye B, White D, Gong G, Perry JA, Ryan KA, Fang Q, Tzoneva G, Pefanis E, Hunt C, Tang Y, Lee L; Regeneron Genetics Center Collaboration‡; Sztalryd-Woodle C, Mitchell BD, Healy M, Streeten EA, Taylor SI, O'Connell JR, Economides AN, Della Gatta G, Shuldiner AR
Citation:
Science. 2021 Dec 3;374(6572):1221-1227. doi: 10.1126/science.abe0348. Epub 2021 Dec 2. PMID: 34855475
Epub:
Not Epub
Abstract:
Increased blood levels of low-density lipoprotein cholesterol (LDL-C) and fibrinogen are independent risk factors for...
Link:
https://www.science.org/doi/10.1126/science.abe0348
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Montasser ME, Van Hout CV, Miloscio L, Howard AD, Rosenberg A, Callaway M, Shen B, Li N, Locke AE, Verweij N, De T, Ferreira MA, Lotta LA, Baras A, Daly TJ, Hartford SA, Lin W, Mao Y, Ye B, White D, Gong G, Perry JA, Ryan KA, Fang Q, Tzoneva G, Pefanis E, Hunt C, Tang Y, Lee L; Regeneron Genetics Center Collaboration‡; Sztalryd-Woodle C, Mitchell BD, Healy M, Streeten EA, Taylor SI, O'Connell JR, Economides AN, Della Gatta G, Shuldiner AR. Genetic and functional evidence links a missense variant in B4GALT1 to lower LDL and fibrinogen. Science. 2021 Dec 3;374(6572):1221-1227. doi: 10.1126/science.abe0348. Epub 2021 Dec 2. PMID: 34855475.

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