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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Downregulation of hepatic stem cell factor by Vivo-Morpholino treatment inhibits mast cell migration and decreases biliary damage/senescence and liver fibrosis in Mdr2−/− mice
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Citation:
Biochem Biophys Acta. 2019;[Epub ahead of print] doi:10.1016/j.bbadis.2019.165557 Epub:
Yes Abstract:
Abstract: Primary sclerosing cholangitis (PSC) is characterized by increased mast cell (MC) infiltration, biliary damage and... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Vik Meadows V, Kennedy L, Hargrove L, Demieville J, Meng F, Virani S, Reinhart E, Kyritsi K, Invernizzi P, Yang Z, Wu N, Liangpunsakul S, Alpini G, Francis H. Downregulation of hepatic stem cell factor by Vivo-Morpholino treatment inhibits mast cell migration and decreases biliary damage/senescence and liver fibrosis in Mdr2−/− mice. Biochem Biophys Acta. 2019;[Epub ahead of print] doi:10.1016/j.bbadis.2019.165557. |
A Complex of U1 snRNP with Cleavage and Polyadenylation Factors Controls Telescripting, Regulating mRNA Transcription in Human Cells
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Citation:
Molec Cell. 2019;[Epub ahead of print] doi:10.1016/j.molcel.2019.08.007 Epub:
Yes Abstract:
Full-length transcription in the majority of human genes depends on U1 snRNP (U1) to co-transcriptionally suppress... Citation Extract: So BR, Di C, Cai Z, Oh J-M, Arai C, Dreyfuss G. A Complex of U1 snRNP with Cleavage and Polyadenylation Factors Controls Telescripting, Regulating mRNA Transcription in Human Cells. Molec Cell. 2019;[Epub ahead of print] doi:10.1016/j.molcel.2019.08.007. |
Multisystem analyses of two Cockayne syndrome associated proteins CSA and CSB reveal shared and unique functions
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Citation:
DNA Repair. 2019;[Epub ahead of print] doi:10.1016/j.dnarep.2019.102696 Epub:
Not Epub Abstract:
Mutations in the CSA and CSB genes are causative of Cockayne syndrome neurological disorder. Since the identification of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wu Z, Yua Q, Zhu X, Xu Y, Wang Y. Multisystem analyses of two Cockayne syndrome associated proteins CSA and CSB reveal shared and unique functions. DNA Repair. 2019;[Epub ahead of print] doi:10.1016/j.dnarep.2019.102696. |
BACE1 Inhibition Using 2’-OMePS Steric Blocking Antisense Oligonucleotides
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Citation:
Genes. 2019:10(9):705. doi:10.3390/genes10090705 Epub:
Not Epub Abstract:
Amyloid beta-peptide is produced by the cleavage of amyloid precursor protein by two secretases, a β-secretase, beta-site... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HEK293 Citation Extract: Chakravarthy M, Veedu RN. BACE1 Inhibition Using 2’-OMePS Steric Blocking Antisense Oligonucleotides. Genes. 2019:10(9):705. doi:10.3390/genes10090705. |
Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2−/− mouse model of primary sclerosing cholangitis (PSC)
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Citation:
EBioMedicine, 2019;[in press] doi:10.1016/j.ebiom.2019.09.013 Epub:
Yes Abstract:
Background: Cholangiocytes are the target cells of cholangiopathies including primary sclerosing cholangitis (PSC). Vimentin is... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Zhou T, Kyritsi K, Wu N, Francis H, Yang Z, Chen L, O'Brien A, Kennedy L, Ceci L, Meadows V, Kusumanchi P, Wu C, Baiocchi L, Skill NJ, Saxena R, Sybenga A, Xie L, Liangpunsakul S, Meng F, Alpini G, Glaser S. Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2−/− mouse model of primary sclerosing cholangitis (PSC). EBioMedicine, 2019;[in press] doi:10.1016/j.ebiom.2019.09.013. |
Sonic Hedgehog repression underlies gigaxonin mutation-induced motor deficits in giant axonal neuropathy
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Citation:
J Clin Invest. 2019;{Epub ahead of print] doi:10.1172/JCI129788 Epub:
Yes Abstract:
Growing evidence shows that alterations occurring at early developmental stages contribute to symptoms manifested in adulthood... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Arribat Y, Mysiak KS, Lescouzères L, Boizot A, Ruiz M, Rossel M, Bomont P. Sonic Hedgehog repression underlies gigaxonin mutation-induced motor deficits in giant axonal neuropathy. J Clin Invest. 2019;{Epub ahead of print] doi:10.1172/JCI129788. |
Biomechanical signaling within the developing zebrafish heart attunes endocardial growth to myocardial chamber dimensions
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Citation:
Nat Comm. 2019;10(1):4113. doi:10.1038/s41467-019-12068-x Epub:
Not Epub Abstract:
Intra-organ communication guides morphogenetic processes that are essential for an organ to carry out complex physiological... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bornhorst D, Xia P, Nakajima H, Dingare C, Herzog W, Lecaudey V, Mochizuki N, Heisenberg C-P, Yelon D, Abdelilah-Seyfried S. Biomechanical signaling within the developing zebrafish heart attunes endocardial growth to myocardial chamber dimensions. Nat Comm. 2019;10(1):4113. doi:10.1038/s41467-019-12068-x. |
Spatio-temporal expression of ANK2 promotes cytokinesis in oocytes
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Citation:
Sci Rep. 2019;9(1):13121. doi:10.1038/s41598-019-49483-5 Epub:
Not Epub Abstract:
In the absence of transcription, the regulation of gene expression in oocytes is controlled almost exclusively at the level of... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Tetkova A, Jansova D, Susor A. Spatio-temporal expression of ANK2 promotes cytokinesis in oocytes. Sci Rep. 2019;9(1):13121. doi:10.1038/s41598-019-49483-5. |
SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring
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Citation:
Neuron. 2019;104:{Epub ahead of print] doi:10.1016/j.neuron.2019.07.013 Epub:
Not Epub Abstract:
Mutations in one SETD5 allele are genetic causes of intellectual disability and autistic spectrum disorders. However, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sessa A, Fagnocchi L, Mastrototaro G, Massimino L, Zaghi M, Indrigo M, Cattaneo S, Martini D, Gabellini C, Pucci C, Fasciani A, Belli R, Taverna S, Andreazzoli M, Zippo A, Broccoli V. SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring. Neuron. 2019;104:{Epub ahead of print] doi:10.1016/j.neuron.2019.07.013. |
RNA Binding Protein CELF2 Regulates Signal-Induced Alternative Polyadenylation by Competing with Enhancers of the Polyadenylation Machinery
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Citation:
Cell Rep. 2019;28(11):P2795-806. doi:10.1016/j.celrep.2019.08.022 Epub:
Not Epub Abstract:
The 3′ UTR (UTR) of human mRNAs plays a critical role in controlling protein expression and function. Importantly, 3′ UTRs of... Delivery Method:
elecroporation Organism or Cell Type:
cell culture: Jurkat Citation Extract: Chatrikhi R, Mallory MJ, Gazzara MR, Agosto LM, Zhu WS, Litterman AJ, Ansel KM, Lynch KW. RNA Binding Protein CELF2 Regulates Signal-Induced Alternative Polyadenylation by Competing with Enhancers of the Polyadenylation Machinery. Cell Rep. 2019;28(11):P2795-806. doi:10.1016/j.celrep.2019.08.022. |