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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
Reverse Genetic Approaches to Investigate the Neurobiology of the Cnidarian Sea Anemone Nematostella vectensis
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Citation:
Methods Mol Biol. 2020;2047:25-43. doi: 10.1007/978-1-4939-9732-9_2 Epub:
Not Epub Abstract:
The cnidarian sea anemone Nematostella vectensis has grown in popularity as a model system to complement the ongoing work in... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Havrilak JA, Layden MJ. Reverse Genetic Approaches to Investigate the Neurobiology of the Cnidarian Sea Anemone Nematostella vectensis. Methods Mol Biol. 2020;2047:25-43. doi: 10.1007/978-1-4939-9732-9_2. |
ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia
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Citation:
Cell Rep. 2019;[Epub ahead of print] doi:10.1016/j.celrep.2019.08.063 Epub:
Yes Abstract:
Mucociliary epithelia provide a first line of defense against pathogens. Impaired regeneration and remodeling of mucociliary... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Haas M, Vázquez JLG, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P. ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia. Cell Rep. 2019;[Epub ahead of print] doi:10.1016/j.celrep.2019.08.063. |
lncrps25 play an essential role in motor neuron development through controlling the expression of olig2 in zebrafish
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Citation:
J Cell Phys. 2019;[Epub ahead of print] doi:10.1002/jcp.29237 Epub:
Yes Abstract:
lncrps25 is an intergenic long noncoding RNA (lncRNA), which is location close to rps25 (ribosomal protein S25) gene, is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gao T, Li J, Li N, Gao Y, Yu L, Zhuang S, Zhao Y, Dong X. lncrps25 play an essential role in motor neuron development through controlling the expression of olig2 in zebrafish. J Cell Phys. 2019;[Epub ahead of print] doi:10.1002/jcp.29237. |
Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b
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Citation:
PLoS Genet. 2019 Sep 23;15(9):e1008306. doi: 10.1371/journal.pgen.1008306. [Epub ahead of print] Epub:
Yes Abstract:
During vertebrate early embryogenesis, the ventral development is directed by the ventral-to-dorsal activity gradient of the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ye D, Wang X, Wei C, He M, Wang H, Wang Y, Zhu Z, Sun Y. Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b. PLoS Genet. 2019 Sep 23;15(9):e1008306. doi: 10.1371/journal.pgen.1008306. [Epub ahead of print]. |
Cadherin switch marks germ layer formation in the diploblastic sea anemone Nematostella vectensis
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Citation:
Development. 2019 Sep 20. pii: dev.174623. doi: 10.1242/dev.174623. [Epub ahead of print] Epub:
Yes Abstract:
Morphogenesis is a shape-building process during development of multicellular organisms. During this process the establishment... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Pukhlyakova EA, Kirillova AO, Kraus YA, Zimmermann B, Technau U. Cadherin switch marks germ layer formation in the diploblastic sea anemone Nematostella vectensis. Development. 2019 Sep 20. pii: dev.174623. doi: 10.1242/dev.174623. [Epub ahead of print]. |
Hexose potentiates peptide-conjugated morpholino oligomer efficacy in cardiac muscles of dystrophic mice in an age-dependent manner
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Citation:
Mol Ther Nucl Acids. 2019 Sep 23;18:341-350. doi: 10.1016/j.omtn.2019.09.012. [Epub ahead of print] Epub:
Not Epub Abstract:
Insufficient delivery of oligonucleotides to muscle and heart remains a barrier for clinical implementation of antisense... Delivery Method:
peptide-linked; intravenous (i.v.) Organism or Cell Type:
mice mdx Citation Extract: Han G, Gu B, Lin C, Ning H, Song J, Gao X, Moulton HM, Yin HF. Hexose potentiates peptide-conjugated morpholino oligomer efficacy in cardiac muscles of dystrophic mice in an age-dependent manner. Mol Ther Nucl Acids. 2019 Sep 23;18:341-350. doi: 10.1016/j.omtn.2019.09.012. [Epub ahead of print]. |
Gene- and tissue-level interactions in normal gastrointestinal development and Hirschsprung disease
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Citation:
Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26697-26708. doi: 10.1073/pnas.1908756116. Epub 2019 Dec 9. PMID: 31818953; PMCID: PMC6936708 Epub:
Not Epub Abstract:
The development of the gut from endodermal tissue to an organ with multiple distinct structures and functions occurs over a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chatterjee S, Nandakumar P, Auer DR, Gabriel SB, Chakravarti A. Gene- and tissue-level interactions in normal gastrointestinal development and Hirschsprung disease. Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26697-26708. doi: 10.1073/pnas.1908756116. Epub 2019 Dec 9. PMID: 31818953; PMCID: PMC6936708. |
Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles
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Citation:
Adv Funct Mater. 2019;[Epub] doi:10.1002/adfm.201906432 Epub:
Not Epub Abstract:
Phosphorodiamidate morpholino oligomers (PMOs) are oligonucleotide analogs that can be used for therapeutic modulation of pre‐... Delivery Method:
nanoparticle Organism or Cell Type:
cell culture: HeLa pLuc/705, mdx52 skeletal myotubes Citation Extract: Kuhn J, Klein PM, Al Danaf N, Nordin JZ, Reinhard S, Loy DM, Höhn M, El Andaloussi S, Lamb DC, Wagner E, Aoki Y, Lehto T, Lächelt U. Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles. Adv Funct Mater. 2019;[Epub] doi:10.1002/adfm.201906432. |
Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals
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Citation:
Nat Comm. 2019;10(1):4269. doi:10.1038/s41467-019-12263-w Epub:
Not Epub Abstract:
Embryonic development yields many different cell types in response to just a few families of inductive signals. The property of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Gentsch GE, Spruce T, Owens NDL, Smith JC. Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals. Nat Comm. 2019;10(1):4269. doi:10.1038/s41467-019-12263-w. |
Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish
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Citation:
Oncotarget. 2020 Mar 31;11(13):1109-1130. doi: 10.18632/oncotarget.27521. PMID: 32284789; PMCID: PMC7138166 Epub:
Not Epub Abstract:
pVHL is a tumor suppressor. The lack of its function leads to various tumors, among which ccRCC (clear cell renal cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kim HR, Santhakumar K, Markham E, Baldera D, Greenald D, Bryant HE, El-Khamisy SF, van Eeden FJ. Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish. Oncotarget. 2020 Mar 31;11(13):1109-1130. doi: 10.18632/oncotarget.27521. PMID: 32284789; PMCID: PMC7138166. |