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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Otoferlin Depletion Results in Abnormal Synaptic Ribbons and Altered Intracellular Calcium Levels in Zebrafish
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Citation:
Sci Rep. 2019;9(1):14273. doi:10.1038/s41598-019-50710-2 Epub:
Not Epub Abstract:
The protein otoferlin plays an essential role at the sensory hair cell synapse. Mutations in otoferlin result in deafness and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Manchanda A, Chatterjee P, Bonventre JA, Haggard DE, Kindt KS, Tanguay RL, Johnson CP. Otoferlin Depletion Results in Abnormal Synaptic Ribbons and Altered Intracellular Calcium Levels in Zebrafish. Sci Rep. 2019;9(1):14273. doi:10.1038/s41598-019-50710-2. |
VDAC1 is essential for neurite maintenance and the inhibition of its oligomerization protects spinal cord from demyelination and facilitates locomotor function recovery after spinal cord injury
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Citation:
Sci Rep. 2019 Oct 1;9(1):14063. doi: 10.1038/s41598-019-50506-4 Epub:
Not Epub Abstract:
During the progression of the neurodegenerative process, mitochondria participates in several intercellular signaling pathways... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: rat primary spinal cord Citation Extract: Paschon V, Morena BC, Correia FF, Beltrame GR, Dos Santos GB, Cristante AF, Kihara AH. VDAC1 is essential for neurite maintenance and the inhibition of its oligomerization protects spinal cord from demyelination and facilitates locomotor function recovery after spinal cord injury. Sci Rep. 2019 Oct 1;9(1):14063. doi: 10.1038/s41598-019-50506-4. |
Histone H3K27 acetylation precedes active transcription during zebrafish zygotic genome activation as revealed by live-cell analysis
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Citation:
Development. 2019 Sep 30;146(19). pii: dev179127. doi: 10.1242/dev.179127 Epub:
Not Epub Abstract:
Histone post-translational modifications are key gene expression regulators, but their rapid dynamics during development remain... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sato Y, Hilbert L, Oda H, Wan Y, Heddleston JM, Chew TL, Zaburdaev V, Keller P, Lionnet T, Vastenhouw N, Kimura H. Histone H3K27 acetylation precedes active transcription during zebrafish zygotic genome activation as revealed by live-cell analysis. Development. 2019 Sep 30;146(19). pii: dev179127. doi: 10.1242/dev.179127. |
NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress
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Citation:
eLife. 2019;8:e49044. doi:10.7554/eLife.49044 Epub:
Not Epub Abstract:
Base excision repair (BER) functions not only in the maintenance of genomic integrity but also in active DNA demethylation and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Han D, Schomacher L, Schüle KM, Mallick M, Musheev MU, Karaulanov E, Krebs L, von Seggern A, Niehrs C. NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress. eLife. 2019;8:e49044. doi:10.7554/eLife.49044. |
Defective excitatory/inhibitory synaptic balance and increased neuron apoptosis in a zebrafish model of Dravet syndrome
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/781393 Epub:
Not Epub Abstract:
Dravet syndrome is a type of severe childhood epilepsy that responds poorly to current anti-epileptic drugs. In recent years,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Brenet A, Hassan-Abdi R, Somkhit J, Yanicostas C, Soussi-Yanicostas N. Defective excitatory/inhibitory synaptic balance and increased neuron apoptosis in a zebrafish model of Dravet syndrome. bioRxiv. 2019;[preprint] doi:10.1101/781393. |
Preservation of zebrafish genetic resources through testis cryopreservation and spermatogonia transplantation
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Citation:
Sci Rep. 2019;9(1):13681. doi:10.1038/s41598-019-50169-1 Epub:
Not Epub Abstract:
Zebrafish is one of the most commonly used model organisms in biomedical, developmental and genetic research. The production of... Citation Extract: Marinović Z, Li Q, Lujić J, Iwasaki Y, Csenki Z, Urbányi B, Yoshizaki G, Horváth Á. Preservation of zebrafish genetic resources through testis cryopreservation and spermatogonia transplantation. Sci Rep. 2019;9(1):13681. doi:10.1038/s41598-019-50169-1. |
Characterization of biklf/klf17-deficient zebrafish in posterior lateral line neuromast and hatching gland development
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Citation:
Sci Rep. 2019;9(1):13680. doi:10.1038/s41598-019-50149-5 Epub:
Not Epub Abstract:
Krüpple-like factors (Klfs) are highly conserved zinc-finger transcription factors that regulate various developmental... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Suzuki H, Ishizaka T, Yanagi K, Sone R, Sunaga Y, Ohga R, Kawahara A. Characterization of biklf/klf17-deficient zebrafish in posterior lateral line neuromast and hatching gland development. Sci Rep. 2019;9(1):13680. doi:10.1038/s41598-019-50149-5. |
Broadening and Enhancing Functions of Antibody by Self-Assembling Multimerization at Cell Surface
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Citation:
ACS Nano. 2019 Sep 25. doi: 10.1021/acsnano.9b04868. [Epub ahead of print] Epub:
Yes Abstract:
Monoclonal antibody therapy has offered treatment benefits. Nonetheless, lack of efficacy still exists, partially because... Organism or Cell Type:
mice Citation Extract: Li L, Wang J, Li Y, Radford DC, Yang J, Kopecek J. Broadening and Enhancing Functions of Antibody by Self-Assembling Multimerization at Cell Surface. ACS Nano. 2019 Sep 25. doi: 10.1021/acsnano.9b04868. [Epub ahead of print]. |
Reverse Genetic Approaches to Investigate the Neurobiology of the Cnidarian Sea Anemone Nematostella vectensis
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Citation:
Methods Mol Biol. 2020;2047:25-43. doi: 10.1007/978-1-4939-9732-9_2 Epub:
Not Epub Abstract:
The cnidarian sea anemone Nematostella vectensis has grown in popularity as a model system to complement the ongoing work in... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Havrilak JA, Layden MJ. Reverse Genetic Approaches to Investigate the Neurobiology of the Cnidarian Sea Anemone Nematostella vectensis. Methods Mol Biol. 2020;2047:25-43. doi: 10.1007/978-1-4939-9732-9_2. |
Towards the identification of causal genes for age-related macular degeneration
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/778613 Epub:
Not Epub Abstract:
Age-related macular degeneration (AMD) is a leading cause of visual impairment in ageing populations and has no radical... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cheng F-F, Zhuang Y-Y, Wen X-R, Xue A, Yang J, Jin Z-B. Towards the identification of causal genes for age-related macular degeneration. bioRxiv. 2019;[preprint] doi:10.1101/778613 . |