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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation
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Citation:
Cell Rep. 2019;29:1082-98. doi:10.1016/j.celrep.2019.09.033 Epub:
Not Epub Abstract:
Chondrolectin (Chodl) is needed for motor axon extension in zebrafish and is dysregulated in mouse models of spinal muscular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Oprişoreanu A-M, Smith HL, Arya S, Webster R, Zhong Z, Wehner D, Cardozo MJ, Becker T, Talbot K, Becker CG. Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation. Cell Rep. 2019;29:1082-98. doi:10.1016/j.celrep.2019.09.033. |
Foxg specifies sensory neurons in the anterior neural plate border of the ascidian embryo
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Citation:
Nat Comm. 2019;10:4911 doi:10.1038/s41467-019-12839-6 Epub:
Not Epub Abstract:
Foxg constitutes a regulatory loop with Fgf8 and plays an important role in the development of anterior placodes and the... Delivery Method:
microinjection Organism or Cell Type:
Ciona robusta (AKA C. intestinalis; ascidian) Citation Extract: Liu B, Satou Y. Foxg specifies sensory neurons in the anterior neural plate border of the ascidian embryo. Nat Comm. 2019;10:4911 doi:10.1038/s41467-019-12839-6. |
Lef1 regulates caveolin expression and caveolin dependent endocytosis, a process necessary for Wnt5a/Ror2 signaling during Xenopus gastrulation
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Citation:
Sci Rep. 2019;9:15645 doi:10.1038/s41598-019-52218-1 Epub:
Not Epub Abstract:
The activation of distinct branches of the Wnt signaling network is essential for regulating early vertebrate development.... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Puzik K, Tonnier V, Opper I, Eckert A, Zhou L, Kratzer M-C, le Noble F, Nienhaus GU, Gradl D. Lef1 regulates caveolin expression and caveolin dependent endocytosis, a process necessary for Wnt5a/Ror2 signaling during Xenopus gastrulation. Sci Rep. 2019;9:15645 doi:10.1038/s41598-019-52218-1. |
MicroRNA-421 confers paclitaxel resistance by binding to the KEAP1 3′UTR and predicts poor survival in non-small cell lung cancer
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Citation:
Cell Death Dis. 2019;10:821. doi:10.1038/s41419-019-2031-1 Epub:
Not Epub Abstract:
MicroRNAs regulate post-transcriptional gene expression and play important roles in multiple cellular processes. In this study... Delivery Method:
intratumoral injection Organism or Cell Type:
cell culture: human NSCLC A549; mouse xenograft Citation Extract: Duan F-G, Wang M-F, Cao Y-B, Li D, Li R-Z, Fan X-X, Khan I, Lai H-L, Zhang Y-Z, Hsiao WW-L, Yao X-J, Wu Q-B, Liu L, Tang I-J, Leung EL-H. MicroRNA-421 confers paclitaxel resistance by binding to the KEAP1 3′UTR and predicts poor survival in non-small cell lung cancer. Cell Death Dis. 2019;10:821. doi:10.1038/s41419-019-2031-1. |
Nanog safeguards early embryogenesis against global activation of maternal β-catenin activity by interfering with TCF factors
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Citation:
bioRxiv. 2019;[preprint] doi:/10.1101/821702 Epub:
Not Epub Abstract:
Maternal β-catenin activity is essential and critical for dorsal induction and its dorsal activation has been thoroughly... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: He M, Zhang R, Zhang F, Jiao S, Ye D, Wang H, Sun Y. Nanog safeguards early embryogenesis against global activation of maternal β-catenin activity by interfering with TCF factors. bioRxiv. 2019;[preprint] doi:/10.1101/821702 . |
Generation of MuRF-GFP transgenic zebrafish models for investigating murf gene expression and protein localization in Smyd1b and Hsp90α1 knockdown embryos
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Citation:
Comp Biochem Physiol B. 2019;[Epub ahead of print] doi:10.1016/j.cbpb.2019.110368 Epub:
Yes Abstract:
Muscle-specific RING-finger proteins (MuRFs) are E3 ubiquitin ligases that play important roles in protein quality control in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li B, Li S, He Q, Du S. Generation of MuRF-GFP transgenic zebrafish models for investigating murf gene expression and protein localization in Smyd1b and Hsp90α1 knockdown embryos. Comp Biochem Physiol B. 2019;[Epub ahead of print] doi:10.1016/j.cbpb.2019.110368. |
Regulation of FXR1 by alternative splicing is required for muscle development and controls liquid-like condensates in muscle cells
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/818476 Epub:
Not Epub Abstract:
Fragile-X mental retardation autosomal homolog-1 (FXR1) is a muscle-enriched RNA-binding protein. FXR1 depletion is perinatally... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Smith JA, Curry EG, Blue RE, Roden C, Dundon SER, Rodríguez-Vargas A, Jordan DC, Chen X, Lyons SW, Crutchley J, Anderson P, Horb ME, Gladfelter AS, Giudice J. Regulation of FXR1 by alternative splicing is required for muscle development and controls liquid-like condensates in muscle cells. bioRxiv. 2019;[preprint] doi:10.1101/818476. |
POLR1B and neural crest cell anomalies in Treacher Collins syndrome type 4
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Citation:
Genet Med. 2019 Oct 24. doi: 10.1038/s41436-019-0669-9. [Epub ahead of print] Epub:
Yes Abstract:
PURPOSE: Treacher Collins syndrome (TCS) is a rare autosomal dominant mandibulofacial dysostosis, with a prevalence of 0.2-1/10... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sanchez E, Laplace-Builhé B, Mau-Them FT, Richard E, Goldenberg A, Toler TL, Guignard T, Gatinois V, Vincent M, Blanchet C, Boland A, Bihoreau MT, Deleuze JF, Olaso R, Nephi W, Lüdecke HJ, Verheij JBGM, Moreau-Lenoir F, Denoyelle F, Rivière JB, Laplanche JL, Willing M, Captier G, Apparailly F, Wieczorek D, Collet C, Djouad F, Geneviève D. POLR1B and neural crest cell anomalies in Treacher Collins syndrome type 4. Genet Med. 2019 Oct 24. doi: 10.1038/s41436-019-0669-9. [Epub ahead of print]. |
Composition dependent phase separation underlies directional flux through the nucleolus
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/809210 Epub:
Not Epub Abstract:
Intracellular bodies such as nucleoli, Cajal bodies, and various signaling assemblies, represent membraneless organelles, or... Citation Extract: Riback JA, Zhu L, Ferrolino MC, Tolbert M, Mitrea DM, Sanders DW, Wei M-T, Kriwacki RW, Brangwynne CP. Composition dependent phase separation underlies directional flux through the nucleolus. bioRxiv. 2019;[preprint] doi:10.1101/809210. |
Interleukin-6 signaling regulates hematopoietic stem cell emergence
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Citation:
Exp Mol Med. 2019 Oct 24;51(10):124. doi: 10.1038/s12276-019-0320-5 Epub:
Not Epub Abstract:
Hematopoietic stem cells (HSCs) produce all lineages of mature blood cells for the lifetime of an organism. In vertebrates,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tie R, Li H, Cai S, Liang Z, Shan W, Wang B, Tan Y, Zheng W, Huang H. Interleukin-6 signaling regulates hematopoietic stem cell emergence. Exp Mol Med. 2019 Oct 24;51(10):124. doi: 10.1038/s12276-019-0320-5. |