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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Myotubularin related protein 7 is essential for the spermatogonial stem cell homeostasis via PI3K/AKT signaling

Authors:
Zhao D, Shen C, Gao T, Li H, Guo Y, Li F, Liu C, Liu Y, Chen X, Zhang X, Wu Y, Yu Y, Lin M, Yuan Y, Chen X, Huang X, Yang S, Yu J, Zhang J, Zheng B
Citation:
Cell Cycle. 2019;[Epub ahead of print] doi:10.1080/15384101.2019.1661174
Epub:
Not Epub
Abstract:
Myotubularin related protein 7 (MTMR7), a key member of the MTMR family, depicts phosphatase activity and is involved in...
Link:
https://www.tandfonline.com/doi/full/10.1080/15384101.2019.1661174
Organism or Cell Type:
mouse testis
Citation Extract:
Zhao D, Shen C, Gao T, Li H, Guo Y, Li F, Liu C, Liu Y, Chen X, Zhang X, Wu Y, Yu Y, Lin M, Yuan Y, Chen X, Huang X, Yang S, Yu J, Zhang J, Zheng B. Myotubularin related protein 7 is essential for the spermatogonial stem cell homeostasis via PI3K/AKT signaling. Cell Cycle. 2019;[Epub ahead of print] doi:10.1080/15384101.2019.1661174.

MicroRNA-mediated control of developmental lymphangiogenesis

Authors:
Jung HM, Hu CT, Fister AM, Davis AE, Castranova D, Pham VN, Price LM, Weinstein BM
Citation:
eLife. 2019;8:e46007. doi: 10.7554/eLife.46007
Epub:
Not Epub
Abstract:
The post-transcriptional mechanisms contributing to molecular regulation of developmental lymphangiogenesis and lymphatic...
Link:
https://elifesciences.org/articles/46007
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jung HM, Hu CT, Fister AM, Davis AE, Castranova D, Pham VN, Price LM, Weinstein BM. MicroRNA-mediated control of developmental lymphangiogenesis. eLife. 2019;8:e46007. doi: 10.7554/eLife.46007.

Loss of CENPF leads to developmental failure in mouse embryos

Authors:
Zhou C-J, Wang X-Y, Han Z, Wang D-H, Ma Y-Z, Liang C-G
Citation:
Cell Cycle. 2019;[Epub ahead of print] doi:10.1080/15384101.2019.1661173
Epub:
Yes
Abstract:
Aneuploidy caused by abnormal chromosome segregation during early embryo development leads to embryonic death or congenital...
Link:
https://www.tandfonline.com/doi/full/10.1080/15384101.2019.1661173
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte, embryo
Citation Extract:
Zhou C-J, Wang X-Y, Han Z, Wang D-H, Ma Y-Z, Liang C-G. Loss of CENPF leads to developmental failure in mouse embryos. Cell Cycle. 2019;[Epub ahead of print] doi:10.1080/15384101.2019.1661173.

Peptide-conjugated oligonucleotides evoke long-lasting myotonic dystrophy correction in patient-derived cells and mice

Authors:
Klein AF, Varela MA, Arandel L, Holland A, Naouar N, Arzumanov A, Seoane D, Revillod L, Bassez G, Ferry A, Jauvin D, Gourdon G, Puymirat J, Gait MJ, Furling D, Wood MJA
Citation:
J Clin Invest. 2019 Nov 1;129(11):4739-4744. doi: 10.1172/JCI128205
Epub:
Not Epub
Abstract:
Antisense oligonucleotides (ASOs) targeting pathologic RNAs have shown promising therapeutic corrections for many genetic...
Link:
https://www.jci.org/articles/view/128205
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: patient-derived muscle DM1 mice
Citation Extract:
Klein AF, Varela MA, Arandel L, Holland A, Naouar N, Arzumanov A, Seoane D, Revillod L, Bassez G, Ferry A, Jauvin D, Gourdon G, Puymirat J, Gait MJ, Furling D, Wood MJA. Peptide-conjugated oligonucleotides evoke long-lasting myotonic dystrophy correction in patient-derived cells and mice. J Clin Invest. 2019 Nov 1;129(11):4739-4744. doi: 10.1172/JCI128205.

Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis

Authors:
Corkins ME, Krneta-Stankic V, Kloc M, McCrea PD, Gladden AB, Miller RK
Citation:
PLoS ONE. 2019;14(8):e0221698. doi:10.1371/journal.pone.0221698
Epub:
Not Epub
Abstract:
Kidneys are composed of numerous ciliated epithelial tubules called nephrons. Each nephron functions to reabsorb nutrients and...
Link:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0221698
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Corkins ME, Krneta-Stankic V, Kloc M, McCrea PD, Gladden AB, Miller RK. Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis. PLoS ONE. 2019;14(8):e0221698. doi:10.1371/journal.pone.0221698.

ARHGEF12 regulates erythropoiesis and is involved in erythroid regeneration after chemotherapy in acute lymphoblastic leukemia patients

Authors:
Xie Y, Gao L, Xu C, Chu L, Gao L, Wu R, Liu Y, Liu T, Sun XJ, Ren R, Tang J, Zheng Y, Zhou Y, Shen S
Citation:
Haematologica. 2019 Aug 29. pii: haematol.2018.210286. doi: 10.3324/haematol.2018.210286. [Epub ahead of print]
Epub:
Yes
Abstract:
Hematopoiesis is a finely regulated process in vertebrates under both homeostatic and stress conditions. By whole exome...
Link:
http://www.haematologica.org/content/early/2019/08/26/haematol.2018.210286.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xie Y, Gao L, Xu C, Chu L, Gao L, Wu R, Liu Y, Liu T, Sun XJ, Ren R, Tang J, Zheng Y, Zhou Y, Shen S. ARHGEF12 regulates erythropoiesis and is involved in erythroid regeneration after chemotherapy in acute lymphoblastic leukemia patients. Haematologica. 2019 Aug 29. pii: haematol.2018.210286. doi: 10.3324/haematol.2018.210286. [Epub ahead of print].

Non-junctional Cadherin3 regulates cell migration and contact inhibition of locomotion via domain-dependent opposing regulations of Rac1

Authors:
Ichikawa T, Stuckenholz C, Davidson LA
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/750752
Epub:
Not Epub
Abstract:
Classical cadherins are well-known primary adhesion molecules responsible for physically connecting neighboring cells and...
Link:
https://www.biorxiv.org/content/10.1101/750752v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ichikawa T, Stuckenholz C, Davidson LA. Non-junctional Cadherin3 regulates cell migration and contact inhibition of locomotion via domain-dependent opposing regulations of Rac1. bioRxiv. 2019;[preprint] doi:10.1101/750752.

Biallelic TANGO1 mutations cause a novel syndromal disease due to hampered cellular collagen secretion

Authors:
Lekszas C, Foresti O, Raote I, Daniel Lietdke D, Koenig E-M, Nanda I, Vona C, De Coster P, Cauwels R, Malhotra V, Haaf T
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/750349
Epub:
Not Epub
Abstract:
The transport and Golgi organization 1 (TANGO1) family proteins have been shown to play pivotal roles in the secretory pathway...
Link:
https://www.biorxiv.org/content/10.1101/750349v1
Delivery Method:
FuGENE HD transfection reagent
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Lekszas C, Foresti O, Raote I, Daniel Lietdke D, Koenig E-M, Nanda I, Vona C, De Coster P, Cauwels R, Malhotra V, Haaf T. Biallelic TANGO1 mutations cause a novel syndromal disease due to hampered cellular collagen secretion. bioRxiv. 2019;[preprint] doi:10.1101/750349.

Sema3E is required for migration of cranial neural crest cells in zebrafish: Implications for the pathogenesis of CHARGE syndrome

Authors:
Liu ZZ, Guo J, Lu Y, Liu W, Fu X, Yao T, Zhou Y, Xu HA
Citation:
Int J Exp Pathol. 2019 Aug 28. doi: 10.1111/iep.12331. [Epub ahead of print]
Epub:
Yes
Abstract:
CHARGE syndrome is a congenital disorder with multiple malformations in the craniofacial structures, and cardiovascular and...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1111/iep.12331
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu ZZ, Guo J, Lu Y, Liu W, Fu X, Yao T, Zhou Y, Xu HA. Sema3E is required for migration of cranial neural crest cells in zebrafish: Implications for the pathogenesis of CHARGE syndrome. Int J Exp Pathol. 2019 Aug 28. doi: 10.1111/iep.12331. [Epub ahead of print].

Genetic compensation by epob in pronephros development in epoa mutant zebrafish

Authors:
She J, Wu Y, Lou B, Lodd E, Klems A, Schmoehl F, Yuan Z, Noble FL, Kroll J
Citation:
Cell Cycle. 2019 Aug 26:1-14. doi: 10.1080/15384101.2019.1656019. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Zebrafish erythropoietin a (epoa) is a well characterized regulator of red blood cell formation. Recent morpholino mediated...
Link:
https://www.tandfonline.com/doi/full/10.1080/15384101.2019.1656019
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
She J, Wu Y, Lou B, Lodd E, Klems A, Schmoehl F, Yuan Z, Noble FL, Kroll J. Genetic compensation by epob in pronephros development in epoa mutant zebrafish. Cell Cycle. 2019 Aug 26:1-14. doi: 10.1080/15384101.2019.1656019. [Epub ahead of print].

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