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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and X. laevis models
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/614750 Epub:
Not Epub Abstract:
The chromosome 3q29 deletion is associated with a range of neurodevelopmental disorders. Here, we used quantitative methods to... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Singh MD, Jensen M, Lasser M, Huber E, Yusuff T, Pizzo L, Lifschutz B, Desai I, Kubina A, Yennawar S, Kim S, Iyer J, Rincon-Limas DE, Lowery LA, Girirajan S. NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and X. laevis models. bioRxiv. 2019;[preprint] doi:10.1101/614750 . |
Asymmetric Hapln1a drives regionalised cardiac ECM expansion and promotes heart morphogenesis during zebrafish development
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/838128 Epub:
Not Epub Abstract:
The mature vertebrate heart develops from a simple linear cardiac tube during early development through a series of highly... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Derrick CJ, Sánchez-Posada J, Hussein F, Tessadori F, Pollitt EJG, Savage AM, Wilkinson RN, Chico TJ, van Eeden FJ, Bakkers J, Noël ES. Asymmetric Hapln1a drives regionalised cardiac ECM expansion and promotes heart morphogenesis during zebrafish development. bioRxiv. 2019;[preprint] doi:10.1101/838128 . |
Alternative polyadenylation of Pax3 controls muscle stem cell fate and muscle function
Citation:
Science. 2019 Nov 8;366(6466):734-738. doi: 10.1126/science.aax1694 Epub:
Not Epub Abstract:
Adult stem cells are essential for tissue homeostasis. In skeletal muscle, muscle stem cells (MuSCs) reside in a quiescent... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: de Morree A, Klein JDD, Gan Q, Farup J, Urtasun A, Kanugovi A, Bilen B, van Velthoven CTJ, Quarta M, Rando TA. Alternative polyadenylation of Pax3 controls muscle stem cell fate and muscle function. Science. 2019 Nov 8;366(6466):734-738. doi: 10.1126/science.aax1694. |
The role of nitric oxide during embryonic wound healing
Citation:
BMC Genomics. 2019 Nov 6;20(1):815. doi: 10.1186/s12864-019-6147-6 Epub:
Not Epub Abstract:
BACKGROUND: The study of the mechanisms controlling wound healing is an attractive area within the field of biology, with it... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Abaffy P, Tomankova S, Naraine R, Kubista M, Sindelka R. The role of nitric oxide during embryonic wound healing. BMC Genomics. 2019 Nov 6;20(1):815. doi: 10.1186/s12864-019-6147-6. |
miR-182-5p is an evolutionarily conserved Tbx5 effector that impacts cardiac development and electrical activity in zebrafish
Citation:
Cell Mol Life Sci. 2019 Nov 4. doi: 10.1007/s00018-019-03343-7. [Epub ahead of print] Epub:
Not Epub Abstract:
To dissect the TBX5 regulatory circuit, we focused on microRNAs (miRNAs) that collectively contribute to make TBX5 a pivotal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Guzzolino E, Pellegrino M, Ahuja N, Garrity D, D'Aurizio R, Groth M, Baumgart M, Hatcher CJ, Mercatanti A, Evangelista M, Ippolito C, Tognoni E, Fukuda R, Lionetti V, Pellegrini M, Cremisi F, Pitto L. miR-182-5p is an evolutionarily conserved Tbx5 effector that impacts cardiac development and electrical activity in zebrafish. Cell Mol Life Sci. 2019 Nov 4. doi: 10.1007/s00018-019-03343-7. [Epub ahead of print]. |
The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response
Citation:
PLoS Pathog. 2019 Nov 4;15(11):e1007634. doi: 10.1371/journal.ppat.1007634. [Epub ahead of print] Epub:
Not Epub Abstract:
Induction of vast transcriptional programs is a central event of innate host responses to viral infections. Here we report a... Delivery Method:
intranasal peptide-linked Organism or Cell Type:
mice Citation Extract: Seifert LL, Si C, Saha D, Sadic M, de Vries M, Ballentine S, Briley A, Wang G, Valero-Jimenez AM, Mohamed A, Schaefer U, Moulton HM, García-Sastre A, Tripathi S, Rosenberg BR, Dittmann M. The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response. PLoS Pathog. 2019 Nov 4;15(11):e1007634. doi: 10.1371/journal.ppat.1007634. [Epub ahead of print]. |
A gene-edited mouse model of limb-girdle muscular dystrophy 2C for testing exon skipping
Citation:
Dis Model Mech. 2019 Nov 4;13(2). pii: dmm040832. doi: 10.1242/dmm.040832 Epub:
Not Epub Abstract:
Limb-girdle muscular dystrophy type 2C is caused by autosomal recessive mutations in the γ-sarcoglycan (SGCG) gene. The most... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice 521ΔT Citation Extract: Demonbreun AR, Wyatt EJ, Fallon KS, Oosterbaan CC, Page PG, Hadhazy M, Quattrocelli M, Barefield DY, McNally EM. A gene-edited mouse model of limb-girdle muscular dystrophy 2C for testing exon skipping. Dis Model Mech. 2019 Nov 4;13(2). pii: dmm040832. doi: 10.1242/dmm.040832. |
Structural and functional studies of TBC1D23 C-terminal domain provide a link between endosomal trafficking and PCH
Citation:
Proc Natl Acad Sci U S A. 2019 Nov 5;116(45):22598-22608. doi: 10.1073/pnas.1909316116. Epub 2019 Oct 17 Epub:
Not Epub Abstract:
Pontocerebellar hypoplasia (PCH) is a group of neurological disorders that affect the development of the brain, in particular,... Organism or Cell Type:
zebrafish Citation Extract: Huang W, Liu Z, Yang F, Zhou H, Yong X, Yang X, Zhou Y, Xue L, Zhang Y, Liu D, Meng W, Zhang W, Zhang X, Shen X, Sun Q, Li L, Ma C, Wei Y, Billadeau DD, Mo X, Jia D. Structural and functional studies of TBC1D23 C-terminal domain provide a link between endosomal trafficking and PCH. Proc Natl Acad Sci U S A. 2019 Nov 5;116(45):22598-22608. doi: 10.1073/pnas.1909316116. Epub 2019 Oct 17. |
Trpc1 as the Missing Link Between the Bmp and Ca2+ Signalling Pathways During Neural Specification in Amphibians
Citation:
Sci Rep. 2019 Nov 5;9(1):16049. doi: 10.1038/s41598-019-52556-0 Epub:
Not Epub Abstract:
In amphibians, the inhibition of bone morphogenetic protein (BMP) in the dorsal ectoderm has been proposed to be responsible... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Néant I, Leung HC, Webb SE, Miller AL, Moreau M, Leclerc C. Trpc1 as the Missing Link Between the Bmp and Ca2+ Signalling Pathways During Neural Specification in Amphibians. Sci Rep. 2019 Nov 5;9(1):16049. doi: 10.1038/s41598-019-52556-0. |
Targeted resequencing identifies genes with recurrent variation in cerebral palsy
Citation:
NPJ Genom Med. 2019 Nov 4;4:27. doi: 10.1038/s41525-019-0101-z. eCollection 2019 Epub:
Not Epub Abstract:
A growing body of evidence points to a considerable and heterogeneous genetic aetiology of cerebral palsy (CP). To identify... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: van Eyk CL, Corbett MA, Frank MSB, Webber DL, Newman M, Berry JG, Harper K, Haines BP, McMichael G, Woenig JA, MacLennan AH, Gecz J. Targeted resequencing identifies genes with recurrent variation in cerebral palsy. NPJ Genom Med. 2019 Nov 4;4:27. doi: 10.1038/s41525-019-0101-z. eCollection 2019. |