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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

The effect of muscle glycogen phosphorylase (Pygm) knockdown on zebrafish morphology

Authors:
Migocka-Patrzałek M, Lewicka A, Elias M, Daczewska M
Citation:
Int J Biochem Cell Biol. 2019 Nov 17:105658. doi: 10.1016/j.biocel.2019.105658. [Epub ahead of print]
Epub:
Yes
Abstract:
Muscle glycogen phosphorylase (PYGM) is a key enzyme in the first step of glycogenolysis. Mutation in the PYGM gene leads to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Migocka-Patrzałek M, Lewicka A, Elias M, Daczewska M. The effect of muscle glycogen phosphorylase (Pygm) knockdown on zebrafish morphology. Int J Biochem Cell Biol. 2019 Nov 17:105658. doi: 10.1016/j.biocel.2019.105658. [Epub ahead of print].

Spreading of a virulence lipid into host membranes promotes mycobacterial pathogenesis

Authors:
Cambier CJ, Banik S, Buonomo JA, Bertozzi C
Citation:
bioRxiv. 2019;[preprint] doi: https://doi.org/10.1101/845081
Epub:
Not Epub
Abstract:
Several lipids of the pathogen Mycobacterium tuberculosis are known to promote virulence at various stages of disease. However...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cambier CJ, Banik S, Buonomo JA, Bertozzi C. Spreading of a virulence lipid into host membranes promotes mycobacterial pathogenesis. bioRxiv. 2019;[preprint] doi: https://doi.org/10.1101/845081 .

Apcdd1 is a dual BMP/Wnt inhibitor in the developing nervous system and skin

Authors:
Vonica A, Bhat N, Phan K, Guo J, Iancu L, Weber JA, Karger A, Cain JW, Wang ECE, DeStefano GM, O’Donnell-Luria AH, Christiano AM, Riley B, Butler SJ, Luria V
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/843714
Epub:
Not Epub
Abstract:
Animal development and homeostasis depend on precise temporal and spatial intercellular signaling. Components shared between...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish, Xenopus laevis
Citation Extract:
Vonica A, Bhat N, Phan K, Guo J, Iancu L, Weber JA, Karger A, Cain JW, Wang ECE, DeStefano GM, O’Donnell-Luria AH, Christiano AM, Riley B, Butler SJ, Luria V. Apcdd1 is a dual BMP/Wnt inhibitor in the developing nervous system and skin. bioRxiv. 2019;[preprint] doi:10.1101/843714 .

IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity

Authors:
Levraud JP, Jouneau L, Briolat V, Laghi V, Boudinot P
Citation:
J Immunol. 2019 Nov 15. pii: ji1900804. doi: 10.4049/jimmunol.1900804. [Epub ahead of print]
Epub:
Yes
Abstract:
The evolution of the IFN system, the major innate antiviral mechanism of vertebrates, remains poorly understood. According to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Levraud JP, Jouneau L, Briolat V, Laghi V, Boudinot P. IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity. J Immunol. 2019 Nov 15. pii: ji1900804. doi: 10.4049/jimmunol.1900804. [Epub ahead of print].

Neutrophil phagocyte oxidase activity controls invasive fungal growth and inflammation in zebrafish

Authors:
Schoen TJ, Rosowski EE, Knox BP, Bennin D, Keller NP, Huttenlocher A
Citation:
J Cell Sci. 2019 Nov 13. pii: jcs.236539. doi: 10.1242/jcs.236539. [Epub ahead of print]
Epub:
Yes
Abstract:
Neutrophils are primary cells of the innate immune system that generate reactive oxygen species (ROS) and mediate host defense...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schoen TJ, Rosowski EE, Knox BP, Bennin D, Keller NP, Huttenlocher A. Neutrophil phagocyte oxidase activity controls invasive fungal growth and inflammation in zebrafish. J Cell Sci. 2019 Nov 13. pii: jcs.236539. doi: 10.1242/jcs.236539. [Epub ahead of print].

Zebrafish Vestigial Like Family Member 4b Is Required for Valvulogenesis Through Sequestration of Transcription Factor Myocyte Enhancer Factor 2c

Authors:
Xue C, Liu X, Wen B, Yang R, Gao S, Tao J, Zhou J
Citation:
Front Cell Dev Biol. 2019;7:277 doi:10.3389/fcell.2019.00277
Epub:
Not Epub
Abstract:
A variety of cardiac transcription factors/cofactors, signaling pathways, and downstream structural genes integrate to form the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xue C, Liu X, Wen B, Yang R, Gao S, Tao J, Zhou J. Zebrafish Vestigial Like Family Member 4b Is Required for Valvulogenesis Through Sequestration of Transcription Factor Myocyte Enhancer Factor 2c. Front Cell Dev Biol. 2019;7:277 doi:10.3389/fcell.2019.00277.

Morphogenetic control of zebrafish cardiac looping by Bmp signaling

Authors:
Lombardo VA, Heise M, Moghtadaei M, Bornhorst D, Männer J, Abdelilah-Seyfried S
Citation:
Development. 2019 Nov 14;146(22). pii: dev180091. doi: 10.1242/dev.180091
Epub:
Not Epub
Abstract:
Cardiac looping is an essential and highly conserved morphogenetic process that places the different regions of the developing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lombardo VA, Heise M, Moghtadaei M, Bornhorst D, Männer J, Abdelilah-Seyfried S. Morphogenetic control of zebrafish cardiac looping by Bmp signaling. Development. 2019 Nov 14;146(22). pii: dev180091. doi: 10.1242/dev.180091.

Ciglitazone - a human PPARγ agonist - disrupts dorsoventral patterning in zebrafish

Authors:
Cheng V, Dasgupta S, Reddam A, Volz DC
Citation:
PeerJ. 2019;7:e8054 doi:10.7717/peerj.8054
Epub:
Not Epub
Abstract:
Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor that regulates lipid/glucose...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cheng V, Dasgupta S, Reddam A, Volz DC. Ciglitazone - a human PPARγ agonist - disrupts dorsoventral patterning in zebrafish. PeerJ. 2019;7:e8054 doi:10.7717/peerj.8054.

Genome-wide suppressor screen identifies USP35/USP38 as therapeutic candidates for ciliopathies

Authors:
Tsai IC, Adams KA, Tzeng JA, Shennib O, Tan PL, Katsanis N
Citation:
JCI Insight. 2019 Nov 14;4(22). pii: 130516. doi: 10.1172/jci.insight.130516
Epub:
Not Epub
Abstract:
The ciliopathies are a group of phenotypically overlapping disorders caused by structural or functional defects in the primary...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tsai IC, Adams KA, Tzeng JA, Shennib O, Tan PL, Katsanis N. Genome-wide suppressor screen identifies USP35/USP38 as therapeutic candidates for ciliopathies. JCI Insight. 2019 Nov 14;4(22). pii: 130516. doi: 10.1172/jci.insight.130516.

Chemokine receptor trafficking coordinates neutrophil clustering and dispersal at wounds in zebrafish

Authors:
Coombs C, Georgantzoglou A, Walker HA, Patt J, Merten N, Poplimont H, Busch-Nentwich EM, Williams S, Kotsi C, Kostenis E, Sarris M
Citation:
Nat Commun. 2019 Nov 14;10(1):5166. doi: 10.1038/s41467-019-13107-3
Epub:
Not Epub
Abstract:
Immune cells congregate at specific loci to fight infections during inflammatory responses, a process that must be transient...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Coombs C, Georgantzoglou A, Walker HA, Patt J, Merten N, Poplimont H, Busch-Nentwich EM, Williams S, Kotsi C, Kostenis E, Sarris M. Chemokine receptor trafficking coordinates neutrophil clustering and dispersal at wounds in zebrafish. Nat Commun. 2019 Nov 14;10(1):5166. doi: 10.1038/s41467-019-13107-3.

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