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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
ZRANB2 and SYF2-mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin
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Citation:
Nucleic Acids Res. 2020 Jan 16. pii: gkz1213. doi: 10.1093/nar/gkz1213. [Epub ahead of print] Epub:
Not Epub Abstract:
Besides analyses of specific alternative splicing (AS) variants, little is known about AS regulatory pathways and programs... Delivery Method:
Endo-Porter PEG; Vivo-Morpholino Organism or Cell Type:
cell culture: MCF7-DoxoR; female Swiss Nu/nu mice intratumoral Citation Extract: Tanaka I, Chakraborty A, Saulnier O, Benoit-Pilven C, Vacher S, Labiod D, Lam EWF, Bièche I, Delattre O, Pouzoulet F, Auboeuf D, Vagner S, Dutertre M. ZRANB2 and SYF2-mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin. Nucleic Acids Res. 2020 Jan 16. pii: gkz1213. doi: 10.1093/nar/gkz1213. [Epub ahead of print]. |
Microglial activation increases cocaine self-administration following adolescent nicotine exposure
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Citation:
Nat Commun. 2020 Jan 16;11(1):306. doi: 10.1038/s41467-019-14173-3 Epub:
Not Epub Abstract:
With the rise of e-cigarette use, teen nicotine exposure is becoming more widespread. Findings from clinical and preclinical... Delivery Method:
intracranial Vivo-Morpholino Organism or Cell Type:
Sprague-Dawley rat Citation Extract: Linker KE, Elabd MG, Tawadrous P, Cano M, Green KN, Wood MA, Leslie FM. Microglial activation increases cocaine self-administration following adolescent nicotine exposure. Nat Commun. 2020 Jan 16;11(1):306. doi: 10.1038/s41467-019-14173-3. |
The NOTCH1-dependent HIF1α/VGLL4/IRF2BP2 oxygen sensing pathway triggers erythropoiesis terminal differentiation
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Citation:
Redox Biol. 2020 Jan;28:101313. doi: 10.1016/j.redox.2019.101313. Epub 2019 Sep 2 Epub:
Not Epub Abstract:
Hypoxia is widely considered as a limiting factor in vertebrate embryonic development, which requires adequate oxygen delivery... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang Y, Liu X, Xie B, Yuan H, Zhang Y, Zhu J. The NOTCH1-dependent HIF1α/VGLL4/IRF2BP2 oxygen sensing pathway triggers erythropoiesis terminal differentiation. Redox Biol. 2020 Jan;28:101313. doi: 10.1016/j.redox.2019.101313. Epub 2019 Sep 2. |
The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer
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Citation:
Elife. 2020 Jan 14;9. pii: e51248. doi: 10.7554/eLife.51248. [Epub ahead of print] Epub:
Not Epub Abstract:
A hallmark of Spemann organizer function is its expression of Wnt antagonists that regulate axial embryonic patterning. Here we... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Chang LS, Kim M, Glinka A, Reinhard C, Niehrs C. The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer. Elife. 2020 Jan 14;9. pii: e51248. doi: 10.7554/eLife.51248. [Epub ahead of print]. |
Antisense targeting of decoy exons can reduce intron retention and increase protein expression in human erythroblasts
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.01.13.902544 Epub:
Not Epub Abstract:
Galanin (Gal) is a peptide with a role in neuroendocrine regulation of the liver. In this study we assessed the role of Gal and... Delivery Method:
electroporation Organism or Cell Type:
cell culture: human erythroblasts Citation Extract: Parra M, Zhang W, Vu J, DeWitt M, Conboy JG. Antisense targeting of decoy exons can reduce intron retention and increase protein expression in human erythroblasts. bioRxiv. 2020;[preprint] doi:10.1101/2020.01.13.902544. |
Co-ordinated targeting of galanin receptors on cholangiocytes and hepatic stellate cells ameliorates liver fibrosis in Mdr2-knockout mice
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Citation:
Am J Pathol. 2020 Jan 14. pii: S0002-9440(20)30003-1. doi: 10.1016/j.ajpath.2019.10.023. [Epub ahead of print] Epub:
Not Epub Abstract:
Galanin (Gal) is a peptide with a role in neuroendocrine regulation of the liver. In this study we assessed the role of Gal and... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Petrescu AD, Grant S, Williams E, Frampton G, Parks N, Blaney H, Davies M, John R, Reinhart EH, McMillin M, DeMorrow S. Co-ordinated targeting of galanin receptors on cholangiocytes and hepatic stellate cells ameliorates liver fibrosis in Mdr2-knockout mice. Am J Pathol. 2020 Jan 14. pii: S0002-9440(20)30003-1. doi: 10.1016/j.ajpath.2019.10.023. [Epub ahead of print]. |
Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model
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Citation:
J Cell Physiol. 2020 Jan 13. doi: 10.1002/jcp.29441. [Epub ahead of print] Epub:
Yes Abstract:
Myosin‐binding protein C 3 (MYBPC3) variants are the most common cause of hypertrophic cardiomyopathy (HCM). HCM is a complex... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Da'as SI, Yalcin HC, Nasrallah GK, Mohamed IA, Nomikos M, Yacoub MH, Fakhro KA. Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model. J Cell Physiol. 2020 Jan 13. doi: 10.1002/jcp.29441. [Epub ahead of print]. |
Leucine-rich repeat containing 8A contributes to the expansion of brain ventricles in zebrafish embryos
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Citation:
Biol Open. 2020 Jan 15. pii: bio.048264. doi: 10.1242/bio.048264. [Epub ahead of print] Epub:
Yes Abstract:
The sodium osmotic gradient is necessary for the initiation of brain ventricle inflation, but a previous study predicted that... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tseng YT, Ko CL, Chang CT, Lee YH, Huang Fu WC, Liu IH. Leucine-rich repeat containing 8A contributes to the expansion of brain ventricles in zebrafish embryos. Biol Open. 2020 Jan 15. pii: bio.048264. doi: 10.1242/bio.048264. [Epub ahead of print]. |
Novel eye genes systematically discovered through an integrated analysis of mouse transcriptomes and phenome
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Citation:
Comput Struct Biotechnol J. 2019 Dec 27;18:73-82. doi: 10.1016/j.csbj.2019.12.009. eCollection 2020 Epub:
Not Epub Abstract:
In the last few decades, reverse genetic and high throughput approaches have been frequently applied to the mouse (Mus musculus... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chiang CY, Ching YH, Chang TY, Hu LS, Yong YS, Keak PY, Mustika I, Lin MD, Liao BY. Novel eye genes systematically discovered through an integrated analysis of mouse transcriptomes and phenome. Comput Struct Biotechnol J. 2019 Dec 27;18:73-82. doi: 10.1016/j.csbj.2019.12.009. eCollection 2020. |
Germ plasm localisation dynamics mark distinct phases of transcriptional and post-transcriptional regulation control in primordial germ cells
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Citation:
https://www.biorxiv.org/content/10.1101/2020.01.12.903336v1 Epub:
Not Epub Abstract:
In many animal models, primordial germ cell (PGC) development depends on maternally-deposited germ plasm to avoid somatic cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: D'Orazio FM, Balwierz P, Guo Y, Rodriguez B, Jasiulewicz A, Vaquerizas JM, Cairns B, Lenhard B, Mueller F. Germ plasm localisation dynamics mark distinct phases of transcriptional and post-transcriptional regulation control in primordial germ cells. https://www.biorxiv.org/content/10.1101/2020.01.12.903336v1. |