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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12152 scientific papers returned from the database with the search filters currently being used below.
There are 12152 scientific papers returned from the database with the search filters currently being used below.
The effect of muscle glycogen phosphorylase (Pygm) knockdown on zebrafish morphology
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Citation:
Int J Biochem Cell Biol. 2019 Nov 17:105658. doi: 10.1016/j.biocel.2019.105658. [Epub ahead of print] Epub:
Yes Abstract:
Muscle glycogen phosphorylase (PYGM) is a key enzyme in the first step of glycogenolysis. Mutation in the PYGM gene leads to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Migocka-Patrzałek M, Lewicka A, Elias M, Daczewska M. The effect of muscle glycogen phosphorylase (Pygm) knockdown on zebrafish morphology. Int J Biochem Cell Biol. 2019 Nov 17:105658. doi: 10.1016/j.biocel.2019.105658. [Epub ahead of print]. |
Apcdd1 is a dual BMP/Wnt inhibitor in the developing nervous system and skin
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Citation:
Dev Biol. 2020 Aug 1;464(1):71-87. doi: 10.1016/j.ydbio.2020.03.015. Epub 2020 Apr 19. PMID: 32320685; PMCID: PMC7307705 Epub:
Not Epub Abstract:
Animal development and homeostasis depend on precise temporal and spatial intercellular signaling. Components shared between... Delivery Method:
microinjection Organism or Cell Type:
zebrafish, Xenopus laevis Citation Extract: Vonica A, Bhat N, Phan K, Guo J, Iancu L, Weber JA, Karger A, Cain JW, Wang ECE, DeStefano GM, O'Donnell-Luria AH, Christiano AM, Riley B, Butler SJ, Luria V. Apcdd1 is a dual BMP/Wnt inhibitor in the developing nervous system and skin. Dev Biol. 2020 Aug 1;464(1):71-87. doi: 10.1016/j.ydbio.2020.03.015. Epub 2020 Apr 19. PMID: 32320685; PMCID: PMC7307705. |
IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity
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Citation:
J Immunol. 2019 Dec 15;203(12):3361-3373. doi: 10.4049/jimmunol.1900804. Epub 2019 Nov 15. PMID: 31732531. Epub:
Yes Abstract:
The evolution of the IFN system, the major innate antiviral mechanism of vertebrates, remains poorly understood. According to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Levraud JP, Jouneau L, Briolat V, Laghi V, Boudinot P. IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity. J Immunol. 2019 Dec 15;203(12):3361-3373. doi: 10.4049/jimmunol.1900804. Epub 2019 Nov 15. PMID: 31732531.. |
Neutrophil phagocyte oxidase activity controls invasive fungal growth and inflammation in zebrafish
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Citation:
J Cell Sci. 2019 Nov 13. pii: jcs.236539. doi: 10.1242/jcs.236539. [Epub ahead of print] Epub:
Yes Abstract:
Neutrophils are primary cells of the innate immune system that generate reactive oxygen species (ROS) and mediate host defense... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Schoen TJ, Rosowski EE, Knox BP, Bennin D, Keller NP, Huttenlocher A. Neutrophil phagocyte oxidase activity controls invasive fungal growth and inflammation in zebrafish. J Cell Sci. 2019 Nov 13. pii: jcs.236539. doi: 10.1242/jcs.236539. [Epub ahead of print]. |
Zebrafish Vestigial Like Family Member 4b Is Required for Valvulogenesis Through Sequestration of Transcription Factor Myocyte Enhancer Factor 2c
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Citation:
Front Cell Dev Biol. 2019;7:277 doi:10.3389/fcell.2019.00277 Epub:
Not Epub Abstract:
A variety of cardiac transcription factors/cofactors, signaling pathways, and downstream structural genes integrate to form the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xue C, Liu X, Wen B, Yang R, Gao S, Tao J, Zhou J. Zebrafish Vestigial Like Family Member 4b Is Required for Valvulogenesis Through Sequestration of Transcription Factor Myocyte Enhancer Factor 2c. Front Cell Dev Biol. 2019;7:277 doi:10.3389/fcell.2019.00277. |
Morphogenetic control of zebrafish cardiac looping by Bmp signaling
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Citation:
Development. 2019 Nov 14;146(22). pii: dev180091. doi: 10.1242/dev.180091 Epub:
Not Epub Abstract:
Cardiac looping is an essential and highly conserved morphogenetic process that places the different regions of the developing... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lombardo VA, Heise M, Moghtadaei M, Bornhorst D, Männer J, Abdelilah-Seyfried S. Morphogenetic control of zebrafish cardiac looping by Bmp signaling. Development. 2019 Nov 14;146(22). pii: dev180091. doi: 10.1242/dev.180091. |
Ciglitazone - a human PPARγ agonist - disrupts dorsoventral patterning in zebrafish
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Citation:
PeerJ. 2019;7:e8054 doi:10.7717/peerj.8054 Epub:
Not Epub Abstract:
Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor that regulates lipid/glucose... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cheng V, Dasgupta S, Reddam A, Volz DC. Ciglitazone - a human PPARγ agonist - disrupts dorsoventral patterning in zebrafish. PeerJ. 2019;7:e8054 doi:10.7717/peerj.8054. |
Genome-wide suppressor screen identifies USP35/USP38 as therapeutic candidates for ciliopathies
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Citation:
JCI Insight. 2019 Nov 14;4(22). pii: 130516. doi: 10.1172/jci.insight.130516 Epub:
Not Epub Abstract:
The ciliopathies are a group of phenotypically overlapping disorders caused by structural or functional defects in the primary... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tsai IC, Adams KA, Tzeng JA, Shennib O, Tan PL, Katsanis N. Genome-wide suppressor screen identifies USP35/USP38 as therapeutic candidates for ciliopathies. JCI Insight. 2019 Nov 14;4(22). pii: 130516. doi: 10.1172/jci.insight.130516. |
Chemokine receptor trafficking coordinates neutrophil clustering and dispersal at wounds in zebrafish
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Citation:
Nat Commun. 2019 Nov 14;10(1):5166. doi: 10.1038/s41467-019-13107-3 Epub:
Not Epub Abstract:
Immune cells congregate at specific loci to fight infections during inflammatory responses, a process that must be transient... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Coombs C, Georgantzoglou A, Walker HA, Patt J, Merten N, Poplimont H, Busch-Nentwich EM, Williams S, Kotsi C, Kostenis E, Sarris M. Chemokine receptor trafficking coordinates neutrophil clustering and dispersal at wounds in zebrafish. Nat Commun. 2019 Nov 14;10(1):5166. doi: 10.1038/s41467-019-13107-3. |
von Willebrand factor D and EGF domains is an evolutionarily conserved and required feature of blastemas capable of multitissue appendage regeneration
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Citation:
Evol Dev. 2020 Jul;22(4):297-311. doi: 10.1111/ede.12332. Epub 2020 Mar 12. PMID: 32163674; PMCID: PMC7390686 Epub:
Not Epub Abstract:
Regenerative ability varies tremendously across species. A common feature of regeneration of appendages such as limbs, fins,... Delivery Method:
injection then electroporation Organism or Cell Type:
Ambystoma mexicanum (Axolotl) Citation Extract: Leigh ND, Sessa S, Dragalzew AC, Payzin-Dogru D, Sousa JF, Aggouras AN, Johnson K, Dunlap GS, Haas BJ, Levin M, Schneider I, Whited JL. von Willebrand factor D and EGF domains is an evolutionarily conserved and required feature of blastemas capable of multitissue appendage regeneration. Evol Dev. 2020 Jul;22(4):297-311. doi: 10.1111/ede.12332. Epub 2020 Mar 12. PMID: 32163674; PMCID: PMC7390686. |