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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Tfam knockdown results in reduction of mtDNA copy number, OXPHOS deficiency and abnormalities in zebrafish embryos

Authors:
Otten ABC, Kamps R, Lindsey P, Gerards M, Pendeville-Samain H, Muller M, van Tienen FHJ, Smeets HJM
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/843318
Epub:
Not Epub
Abstract:
High mitochondrial DNA (mtDNA) copy numbers are essential for oogenesis and embryogenesis and correlate with fertility of...
Link:
https://www.biorxiv.org/content/10.1101/843318v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Otten ABC, Kamps R, Lindsey P, Gerards M, Pendeville-Samain H, Muller M, van Tienen FHJ, Smeets HJM. Tfam knockdown results in reduction of mtDNA copy number, OXPHOS deficiency and abnormalities in zebrafish embryos. bioRxiv. 2019;[preprint] doi:10.1101/843318 .

von Willebrand Factor D and EGF Domains is an evolutionarily conserved and required feature of blastemas capable of multi-tissue appendage regeneration

Authors:
Leigh ND, Sessa S, Dragalzew AC, Payzin-Dogru D, Sousa JF, Aggouras AN, Johnson K, Dunlap GS, Haas BJ, Levin M, Schneider I, Whited JL
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/842948
Epub:
Not Epub
Abstract:
Regenerative ability varies tremendously across species. A common feature of regeneration of appendages such as limbs, fins,...
Link:
https://www.biorxiv.org/content/10.1101/842948v2
Delivery Method:
injection then electroporation
Organism or Cell Type:
Ambystoma mexicanum (Axolotl)
Citation Extract:
Leigh ND, Sessa S, Dragalzew AC, Payzin-Dogru D, Sousa JF, Aggouras AN, Johnson K, Dunlap GS, Haas BJ, Levin M, Schneider I, Whited JL. von Willebrand Factor D and EGF Domains is an evolutionarily conserved and required feature of blastemas capable of multi-tissue appendage regeneration. bioRxiv. 2019;[preprint] doi:10.1101/842948.

Role of the visual experience-dependent nascent proteome in neuronal plasticity

Authors:
Liu HH, McClatchy DB, Schiapparelli L, Shen W, Yates JR 3rd, Cline HT
Citation:
Elife. 2018 Feb 7;7. pii: e33420. doi: 10.7554/eLife.33420
Epub:
Not Epub
Abstract:
Experience-dependent synaptic plasticity refines brain circuits during development. To identify novel protein synthesis-...
Link:
https://elifesciences.org/articles/33420
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Liu HH, McClatchy DB, Schiapparelli L, Shen W, Yates JR 3rd, Cline HT. Role of the visual experience-dependent nascent proteome in neuronal plasticity. Elife. 2018 Feb 7;7. pii: e33420. doi: 10.7554/eLife.33420.

HDAC3 But not HDAC2 Mediates Visual Experience-Dependent Radial Glia Proliferation in the Developing Xenopus Tectum

Authors:
Gao J, Ruan H, Qi X, Tao Y, Guo X, Shen W
Citation:
Front Cell Neurosci. 2016 Sep 27;10:221. eCollection 2016
Epub:
Not Epub
Abstract:
Radial glial cells (RGs) are one of the important progenitor cells that can differentiate into neurons or glia to form...
Link:
https://www.frontiersin.org/articles/10.3389/fncel.2016.00221/full
Delivery Method:
injection then electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gao J, Ruan H, Qi X, Tao Y, Guo X, Shen W. HDAC3 But not HDAC2 Mediates Visual Experience-Dependent Radial Glia Proliferation in the Developing Xenopus Tectum. Front Cell Neurosci. 2016 Sep 27;10:221. eCollection 2016.

Adamts18 deficiency in zebrafish embryo causes defective trunk angiogenesis and caudal vein plexus formation

Authors:
Lu T, Zhang T, Wang C, Yang N, Pan YH, Dang S, Zhang W
Citation:
Biochem Biophys Res Commun. 2019 Nov 8. pii: S0006-291X(19)32118-7. doi: 10.1016/j.bbrc.2019.10.202. [Epub ahead of print]
Epub:
Yes
Abstract:
ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin type I motifs) enzymes play an important role in various...
Link:
https://www.sciencedirect.com/science/article/pii/S0006291X19321187
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu T, Zhang T, Wang C, Yang N, Pan YH, Dang S, Zhang W. Adamts18 deficiency in zebrafish embryo causes defective trunk angiogenesis and caudal vein plexus formation. Biochem Biophys Res Commun. 2019 Nov 8. pii: S0006-291X(19)32118-7. doi: 10.1016/j.bbrc.2019.10.202. [Epub ahead of print].

The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension

Authors:
Morikawa M, Mitani Y, Holmborn K, Kato T, Koinuma D, Maruyama J, Vasilaki E, Sawada H, Kobayashi M, Ozawa T, Morishita Y, Bessho Y, Maeda S, Ledin J, Aburatani H, Kageyama R, Maruyama K, Heldin C-H, Miyazono K
Citation:
Sci Signal. 2019;12(607):eaay4430. doi:10.1126/scisignal.aay4430
Epub:
Not Epub
Abstract:
Dysregulated bone morphogenetic protein (BMP) signaling in endothelial cells (ECs) is implicated in vascular diseases such as...
Link:
https://stke.sciencemag.org/content/12/607/eaay4430.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Morikawa M, Mitani Y, Holmborn K, Kato T, Koinuma D, Maruyama J, Vasilaki E, Sawada H, Kobayashi M, Ozawa T, Morishita Y, Bessho Y, Maeda S, Ledin J, Aburatani H, Kageyama R, Maruyama K, Heldin C-H, Miyazono K. The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension. Sci Signal. 2019;12(607):eaay4430. doi:10.1126/scisignal.aay4430 .

[Evaluation of Morpholino antisense oligos' role on BCR-ABL gene silencing in the K562 cell line]

Authors:
Haririan M, Kaviani S, Soleimani M, Noruzinia M, Abroun S, Rasi Ghaemi S, Delalat B
Citation:
Yakhteh Medical Journal. 2010;12(2):241-248
Epub:
Not Epub
Abstract:
Objective: Chronic myeloid leukemia (CML) develops when a hematopoietic stem cell acquires the BCR/ABL fusion gene. This causes...
Link:
https://pesquisa.bvsalud.org/gim/resource/en/emr-98595
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: K562, Jurkat
Citation Extract:
Haririan M, Kaviani S, Soleimani M, Noruzinia M, Abroun S, Rasi Ghaemi S, Delalat B. [Evaluation of Morpholino antisense oligos' role on BCR-ABL gene silencing in the K562 cell line]. Yakhteh Medical Journal. 2010;12(2):241-248.

microRNA-1 Regulates NCC Migration and Differentiation by Targeting sec63

Authors:
Wang D, Weng Y, Guo S, Qin W, Ni J, Yu L, Zhang Y, Zhao Q, Ben J, Ma J
Citation:
Int J Biol Sci. 2019;15(12):2538-2547. doi:10.7150/ijbs.35357
Epub:
Not Epub
Abstract:
Background/Aims: Neural crest cells play a vital role in craniofacial development, microRNA-1 (miR-1) is essential in...
Link:
https://www.ijbs.com/v15p2538
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang D, Weng Y, Guo S, Qin W, Ni J, Yu L, Zhang Y, Zhao Q, Ben J, Ma J. microRNA-1 Regulates NCC Migration and Differentiation by Targeting sec63. Int J Biol Sci. 2019;15(12):2538-2547. doi:10.7150/ijbs.35357.

Acidified water impairs the lateral line system of zebrafish embryos

Authors:
Lin LY, Hung GY, Yeh YH, Chen SW, Horng JL
Citation:
Aquat Toxicol. 2019 Nov 3;217:105351. doi: 10.1016/j.aquatox.2019.105351. [Epub ahead of print]
Epub:
Yes
Abstract:
Acidification of freshwater ecosystems is recognized as a global environmental problem. However, the influence of acidic water...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0166445X1930284X
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin LY, Hung GY, Yeh YH, Chen SW, Horng JL. Acidified water impairs the lateral line system of zebrafish embryos. Aquat Toxicol. 2019 Nov 3;217:105351. doi: 10.1016/j.aquatox.2019.105351. [Epub ahead of print].

A Hypomorphic Cystathionine ß-Synthase Gene Contributes to Cavefish Eye Loss by Disrupting Optic Vasculature

Authors:
Ma L, Gore AV, Castranova D, Shi J, Ng M, Tomins KA, van der Weele CM, Weinstein BM, Jeffery WR
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/805804
Epub:
Not Epub
Abstract:
Vestigial structures are key indicators of evolutionary descent but the mechanisms underlying their development are poorly...
Link:
https://www.biorxiv.org/content/10.1101/805804v1.full
Delivery Method:
microinjection
Organism or Cell Type:
Astyanax mexicanus (cavefish)
Citation Extract:
Ma L, Gore AV, Castranova D, Shi J, Ng M, Tomins KA, van der Weele CM, Weinstein BM, Jeffery WR. A Hypomorphic Cystathionine ß-Synthase Gene Contributes to Cavefish Eye Loss by Disrupting Optic Vasculature. bioRxiv. 2019;[preprint] doi:10.1101/805804.

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