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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Bi-allelic GOT2 Mutations Cause a Treatable Malate-Aspartate Shuttle-Related Encephalopathy
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Citation:
Am J Hum Genet. 2019;[Epub ahead of print] 10.1016/j.ajhg.2019.07.015 Epub:
Yes Abstract:
Early-infantile encephalopathies with epilepsy are devastating conditions mandating an accurate diagnosis to guide proper... Organism or Cell Type:
zebrafish Citation Extract: van Karnebeek CDM, Ramos RJ, Wen X-Y, Tarailo-Graovac M, Gleeson JG, Skrypnyk C, Brand-Arzamendi K, Karbassi F, Issa MY, van der Lee R, Drögemöller BI, Koster J, Rousseau J, Campeau PM, Wang Y, Cao F, Li M, Ruiter J, Ciapaite J, Kluijtmans LAJ, Willemsen MAAP, Jans JJ, Ross CJ, Wintjes LT, Rodenburg YJ, Huigen MCDG, Jia Z, Waterham ER, Wasserman WW, Wanders RJA, Verhoeven-Duif NM, Zaki MS, Wevers RA. Bi-allelic GOT2 Mutations Cause a Treatable Malate-Aspartate Shuttle-Related Encephalopathy. Am J Hum Genet. 2019;[Epub ahead of print] 10.1016/j.ajhg.2019.07.015 . |
Quiescent cells actively replenish CENP-A nucleosomes to maintain centromere identity and proliferative potential
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Citation:
Dev Cell. 2019;[Epub ahead of print] doi:10.1016/j.devcel.2019.07.016 Epub:
Yes Abstract:
Centromeres provide a robust model for epigenetic inheritance as they are specified by sequence-independent mechanisms... Delivery Method:
microinjection Organism or Cell Type:
Patiria miniata (starfish) Citation Extract: Swartz SZ, McKay LS, Su K-C, Padeganeh A, Paul S. Maddox PS, Knouse KA, Cheeseman IM.. Quiescent cells actively replenish CENP-A nucleosomes to maintain centromere identity and proliferative potential. Dev Cell. 2019;[Epub ahead of print] doi:10.1016/j.devcel.2019.07.016. |
Donepezil modulates amyloid precursor protein endocytosis and reduction by up-regulation of SNX33 expression in primary cortical neurons
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Citation:
Sci Rep. 2019;9:11922. doi:10.1038/s41598-019-47462-4 Epub:
Not Epub Abstract:
Donepezil, a therapeutic drug for Alzheimer’s disease, ameliorates cognitive dysfunction through selective inhibition of... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: rat primary cortical neurons Citation Extract: Takada-Takatori Y, Nakagawa S, Kimata R, Nao Y, Mizukawa Y, Urushidani T, Izumi Y, Akaike A, Tsuchida K, Kume T. Donepezil modulates amyloid precursor protein endocytosis and reduction by up-regulation of SNX33 expression in primary cortical neurons. Sci Rep. 2019;9:11922. doi:10.1038/s41598-019-47462-4. |
A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling
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Citation:
Cell Rep. 2019;28(7):1907-22. doi:10.1016/j.celrep.2019.07.025 Epub:
Not Epub Abstract:
CEP104 is an evolutionarily conserved centrosomal and ciliary tip protein. CEP104 loss-of-function mutations are reported in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Frikstad K-AM, Molinari E, Thoresen M, Roepman R, Sayer JA, Patzke S. A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling. Cell Rep. 2019;28(7):1907-22. doi:10.1016/j.celrep.2019.07.025. |
Gulp1 controls Eph/ephrin trogocytosis and is important for cell rearrangements during development
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Citation:
J Cell Biol. 2019;]Epub ahead of print] doi:10.1083/jcb.201901032 Epub:
Yes Abstract:
Trogocytosis, in which cells nibble away parts of neighboring cells, is an intercellular cannibalism process conserved from... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Gong J, Gaitanos TN, Luu O, Huang Y, Gaitanos L, Lindner J, Winklbauer R, Rüdiger Klein R. Gulp1 controls Eph/ephrin trogocytosis and is important for cell rearrangements during development. J Cell Biol. 2019;]Epub ahead of print] doi:10.1083/jcb.201901032. |
In Vitro Validation of Phosphorodiamidate Morpholino Oligomers
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Citation:
Molecules. 2019;24(6):2922 doi:0.3390/molecules24162922 Epub:
Not Epub Abstract:
One of the crucial aspects of screening antisense oligonucleotides destined for therapeutic application is confidence that the... Delivery Method:
electroporation Lipofectin Lipofectamine Endo-Porter Organism or Cell Type:
cell culture: human dermal fibroblasts, human myoblasts Citation Extract: Aung-Htut MT, McIntosh CS, West KA, Fletcher S, Wilton SD. In Vitro Validation of Phosphorodiamidate Morpholino Oligomers. Molecules. 2019;24(6):2922 doi:0.3390/molecules24162922. |
U1 snRNP regulates cancer cell migration and invasion
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/730515 Epub:
Not Epub Abstract:
Stimulated cells and cancer cells have widespread shortening of mRNA 3′-utranslated regions (3′UTRs) and switches to shorter... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HeLa, A549, MCF-7 and MB-231 Citation Extract: Oh J-M, Venters CC, Di C, Pinto AM, Wan L, Younis I, Cai Z, Arai C, So BR, Dreyfuss G. U1 snRNP regulates cancer cell migration and invasion. bioRxiv. 2019;[preprint] doi:10.1101/730515 . |
De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies
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Citation:
Am J Hum Genet. 2019;[Epub ahead of print] doi:10.1016/j.ajhg.2019.07.005 Epub:
Yes Abstract:
The identification of genetic variants implicated in human developmental disorders has been revolutionized by second-generation... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Holt RJ, Young RM, Crespo B, Ceroni F, Curry CJ, Bellacchio E, Bax DA, Ciolfi A, Simon M, Fagerberg CR, van Binsbergen E, De Luca A, Memo L, Dobyns WB, Mohammed AA, Clokie SJH, Seco CZ, Jiang Y-H, Sørensen KP, Andersen H, Sullivan J, Powis Z, Chassevent A, Smith-Hicks C, Petrovski S, Antoniadi T, Shashi V, Gelb BD, Wilson SW, Gerrelli D, Tartaglia M, Chassaing N, Calvas P, Ragge NK. De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies. Am J Hum Genet. 2019;[Epub ahead of print] doi:10.1016/j.ajhg.2019.07.005. |
Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium
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Citation:
Nat Comm. 2019;10(1):3577. doi:10.1038/s41467-019-11423-2 Epub:
Not Epub Abstract:
Haematopoietic stem cells are generated from the haemogenic endothelium (HE) located in the floor of the dorsal aorta (DA).... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bonkhofer F, Rispoli R, Pinheiro P, Krecsmarik M, Schneider-Swales J, Tsang IHC, de Bruijn M, Monteiro R, Peterkin T, Patient R. Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium. Nat Comm. 2019;10(1):3577. doi:10.1038/s41467-019-11423-2. |
TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes
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Citation:
J Virol. 2019;[Epub ahead of print] doi:10.1128/JVI.00649-19 Epub:
Yes Abstract:
Cleavage of influenza virus hemagglutinin (HA) by host cell proteases is essential for virus infectivity and spread. We... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: primary human bronchial epithelial cells (HBEC), primary type II alveolar epithelial cells (AECII) and Calu-3 cells Citation Extract: Limburg H, Harbig A, Bestle D, Stein DA, Moulton HM, Jaeger J, Janga H, Hardes K, Koepke J, Schulte L, Koczulla AR, Schmeck B, Klenk H-D, Böttcher-Friebertshäuser E. TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes. J Virol. 2019;[Epub ahead of print] doi:10.1128/JVI.00649-19. |