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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

IRSp53 shapes the plasma membrane and controls polarized transport at the nascent lumen during epithelial morphogenesis

Authors:
Bisi S, Rizvi SA, Marchesi S, Carra D, Beznoussenko GV, Ferrara I, Deflorian G, Mironov A, Bertalot G, Pisati F, Oldani A, Cattaneo A, Pece S, Viale G, Bachi A, Tripodo C, Scita G, Disanza A
Citation:
bioRxiv. 2019;[preprint] doi: https://doi.org/10.1101/856369
Epub:
Not Epub
Abstract:
Establishment of apical–basal cell polarity is necessary for generation of luminal and tubular structures during epithelial...
Link:
https://www.biorxiv.org/content/10.1101/856369v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bisi S, Rizvi SA, Marchesi S, Carra D, Beznoussenko GV, Ferrara I, Deflorian G, Mironov A, Bertalot G, Pisati F, Oldani A, Cattaneo A, Pece S, Viale G, Bachi A, Tripodo C, Scita G, Disanza A. IRSp53 shapes the plasma membrane and controls polarized transport at the nascent lumen during epithelial morphogenesis. bioRxiv. 2019;[preprint] doi: https://doi.org/10.1101/856369 .

Massive centriole production can occur in the absence of deuterosomes in multiciliated cells

Authors:
Mercey O, Levine MS, LoMastro GM, Rostaing P, Brotslaw E, Gomez V, Kumar A, Spassky N, Mitchell BJ, Meunier A, Holland AJ
Citation:
Nat Cell Biol. 2019;21:1544–1552. doi: 10.1038/s41556-019-0427-x.
Epub:
Not Epub
Abstract:
Multiciliated cells (MCCs) amplify large numbers of centrioles that convert into basal bodies, which are required for producing...
Link:
https://www.nature.com/articles/s41556-019-0427-x
Organism or Cell Type:
cell culture: Xenopus epithelial cells
Citation Extract:
Mercey O, Levine MS, LoMastro GM, Rostaing P, Brotslaw E, Gomez V, Kumar A, Spassky N, Mitchell BJ, Meunier A, Holland AJ. Massive centriole production can occur in the absence of deuterosomes in multiciliated cells. Nat Cell Biol. 2019;21:1544–1552. doi: 10.1038/s41556-019-0427-x..

Synaptotagmin 1 regulates cortical granule exocytosis during mouse oocyte activation

Authors:
Zhu XL, Li SF, Zhang XQ, Xu H, Luo YQ, Yi YH, Lv LJ, Zhang CH, Wang ZB, Ouyang YC, Hou Y, Schatten H, Liu FH
Citation:
Zygote. 2019 Dec 2:1-6. doi: 10.1017/S0967199419000704. [Epub ahead of print]
Epub:
Yes
Abstract:
Synaptotagmin 1 (Syt1) is an abundant and important presynaptic vesicle protein that binds Ca2+ for the regulation of synaptic...
Link:
https://www.cambridge.org/core/journals/zygote/article/synaptotagmin-1-regulates-cortical-granule-exocytosis-during-mouse-oocyte-activation/5405692ACFC2A162759657EAEC76C815
Organism or Cell Type:
mouse oocyte
Citation Extract:
Zhu XL, Li SF, Zhang XQ, Xu H, Luo YQ, Yi YH, Lv LJ, Zhang CH, Wang ZB, Ouyang YC, Hou Y, Schatten H, Liu FH. Synaptotagmin 1 regulates cortical granule exocytosis during mouse oocyte activation. Zygote. 2019 Dec 2:1-6. doi: 10.1017/S0967199419000704. [Epub ahead of print].

Abnormal development of zebrafish after knockout and knockdown of ribosomal protein L10a

Authors:
Palasin K, Uechi T, Yoshihama M, Srisowanna N, Choijookhuu N, Hishikawa Y, Kenmochi N, Chotigeat W
Citation:
Sci Rep. 2019 Dec 2;9(1):18130. doi: 10.1038/s41598-019-54544-w
Epub:
Not Epub
Abstract:
In this study, to investigate the secondary function of Rpl10a in zebrafish development, morpholino antisense oligonucleotides...
Link:
https://www.nature.com/articles/s41598-019-54544-w
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Palasin K, Uechi T, Yoshihama M, Srisowanna N, Choijookhuu N, Hishikawa Y, Kenmochi N, Chotigeat W. Abnormal development of zebrafish after knockout and knockdown of ribosomal protein L10a. Sci Rep. 2019 Dec 2;9(1):18130. doi: 10.1038/s41598-019-54544-w.

Systematic detection of Mendelian and non-Mendelian variants associated with retinitis pigmentosa by genome-wide association study

Authors:
Nishiguchi KM, Miya F, Mori Y, Fujita K, Akiyama M, Kamatani T, Koyanagi Y, Kota S, Takigawa T, Ueno S, Tsugita M, Kunikata H, Cisarova K, Nishino J, Murakami A, Abe T, Momozawa Y, Terasaki H, Wada Y, Sonoda K-H, Rivolta C, Ishibashi T, Tsunoda T, Tsujikawa M, Ikeda Y, Nakazawa T
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/859744
Epub:
Not Epub
Abstract:
To uncover genetic basis of autosomal recessive retinitis pigmentosa (ARRP), we applied 2-step genome-wide association study (...
Link:
https://www.biorxiv.org/content/10.1101/859744v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nishiguchi KM, Miya F, Mori Y, Fujita K, Akiyama M, Kamatani T, Koyanagi Y, Kota S, Takigawa T, Ueno S, Tsugita M, Kunikata H, Cisarova K, Nishino J, Murakami A, Abe T, Momozawa Y, Terasaki H, Wada Y, Sonoda K-H, Rivolta C, Ishibashi T, Tsunoda T, Tsujikawa M, Ikeda Y, Nakazawa T. Systematic detection of Mendelian and non-Mendelian variants associated with retinitis pigmentosa by genome-wide association study. bioRxiv. 2019;[preprint] doi:10.1101/859744.

Cell-fate plasticity, adhesion and cell sorting complementarily establish a sharp midbrain-hindbrain boundary

Authors:
Kesavan G, Hans S, Brand M
Citation:
bioRxiv. 2019:[preprint] doi:10.1101/857870
Epub:
Not Epub
Abstract:
The formation and maintenance of sharp boundaries between groups of cells play a vital role during embryonic development as...
Link:
https://www.biorxiv.org/content/10.1101/857870v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kesavan G, Hans S, Brand M. Cell-fate plasticity, adhesion and cell sorting complementarily establish a sharp midbrain-hindbrain boundary. bioRxiv. 2019:[preprint] doi:10.1101/857870 .

Sam68 binds Alu-rich introns in SMN and promotes pre-mRNA circularization

Authors:
Pagliarini V, Jolly A, Bielli P, Di Rosa V, De la Grange P, Sette C
Citation:
Nucleic Acids Res. 2019 Nov 28. pii: gkz1117. doi: 10.1093/nar/gkz1117. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The Spinal Muscular Atrophy (SMA) gene SMN was recently duplicated (SMN1 and SMN2) in higher primates. Furthermore, invasion of...
Link:
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkz1117/5645010
Delivery Method:
cell scraping
Organism or Cell Type:
cell culture: human SMA type-I fibroblasts GM03813
Citation Extract:
Pagliarini V, Jolly A, Bielli P, Di Rosa V, De la Grange P, Sette C. Sam68 binds Alu-rich introns in SMN and promotes pre-mRNA circularization. Nucleic Acids Res. 2019 Nov 28. pii: gkz1117. doi: 10.1093/nar/gkz1117. [Epub ahead of print].

The Paf1 Complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors

Authors:
Jurynec MJ, Bai X, Bisgrove BW, Jackson H, Nechiporuk A, Palu RAS, Grunwald HA, Su YC, Hoshijima K, Yost HJ, Zon LI, Grunwald DJ
Citation:
Development. 2019 Nov 29. pii: dev.180133. doi: 10.1242/dev.180133. [Epub ahead of print]
Epub:
Yes
Abstract:
Multipotent progenitor populations are necessary for generating diverse tissue types during embryogenesis. We show the...
Link:
https://dev.biologists.org/content/early/2019/11/25/dev.180133
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jurynec MJ, Bai X, Bisgrove BW, Jackson H, Nechiporuk A, Palu RAS, Grunwald HA, Su YC, Hoshijima K, Yost HJ, Zon LI, Grunwald DJ. The Paf1 Complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors. Development. 2019 Nov 29. pii: dev.180133. doi: 10.1242/dev.180133. [Epub ahead of print].

Exon-Mediated Activation of Transcription Starts

Authors:
Fiszbein A, Krick KS, Begg BE, Burge CB
Citation:
Cell. 2019;[epub ahead of print] doi:10.1016/j.cell.2019.11.002
Epub:
Yes
Abstract:
The processing of RNA transcripts from mammalian genes occurs in proximity to their transcription. Here, we describe a...
Link:
https://www.cell.com/cell/pdf/S0092-8674(19)31223-1.pdf
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: mouse fibroblasts
Citation Extract:
Fiszbein A, Krick KS, Begg BE, Burge CB. Exon-Mediated Activation of Transcription Starts. Cell. 2019;[epub ahead of print] doi:10.1016/j.cell.2019.11.002.

Chemokine-biased robust self-organizing polarization of migrating cells in vivo

Authors:
Olguin-Olguin A, Aalto A, Maugis B, Reichman-Fried M, Raz E
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/857623
Epub:
Not Epub
Abstract:
The mechanisms facilitating the establishment of front-rear polarity in migrating cells are not fully understood, in particular...
Link:
https://www.biorxiv.org/content/10.1101/857623v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Olguin-Olguin A, Aalto A, Maugis B, Reichman-Fried M, Raz E. Chemokine-biased robust self-organizing polarization of migrating cells in vivo. bioRxiv. 2019;[preprint] doi:10.1101/857623.

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