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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
MicroRNA-421 confers paclitaxel resistance by binding to the KEAP1 3′UTR and predicts poor survival in non-small cell lung cancer
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Citation:
Cell Death Dis. 2019;10:821. doi:10.1038/s41419-019-2031-1 Epub:
Not Epub Abstract:
MicroRNAs regulate post-transcriptional gene expression and play important roles in multiple cellular processes. In this study... Delivery Method:
intratumoral injection Organism or Cell Type:
cell culture: human NSCLC A549; mouse xenograft Citation Extract: Duan F-G, Wang M-F, Cao Y-B, Li D, Li R-Z, Fan X-X, Khan I, Lai H-L, Zhang Y-Z, Hsiao WW-L, Yao X-J, Wu Q-B, Liu L, Tang I-J, Leung EL-H. MicroRNA-421 confers paclitaxel resistance by binding to the KEAP1 3′UTR and predicts poor survival in non-small cell lung cancer. Cell Death Dis. 2019;10:821. doi:10.1038/s41419-019-2031-1. |
Nanog safeguards early embryogenesis against global activation of maternal β-catenin activity by interfering with TCF factors
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Citation:
bioRxiv. 2019;[preprint] doi:/10.1101/821702 Epub:
Not Epub Abstract:
Maternal β-catenin activity is essential and critical for dorsal induction and its dorsal activation has been thoroughly... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: He M, Zhang R, Zhang F, Jiao S, Ye D, Wang H, Sun Y. Nanog safeguards early embryogenesis against global activation of maternal β-catenin activity by interfering with TCF factors. bioRxiv. 2019;[preprint] doi:/10.1101/821702 . |
Generation of MuRF-GFP transgenic zebrafish models for investigating murf gene expression and protein localization in Smyd1b and Hsp90α1 knockdown embryos
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Citation:
Comp Biochem Physiol B. 2019;[Epub ahead of print] doi:10.1016/j.cbpb.2019.110368 Epub:
Yes Abstract:
Muscle-specific RING-finger proteins (MuRFs) are E3 ubiquitin ligases that play important roles in protein quality control in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li B, Li S, He Q, Du S. Generation of MuRF-GFP transgenic zebrafish models for investigating murf gene expression and protein localization in Smyd1b and Hsp90α1 knockdown embryos. Comp Biochem Physiol B. 2019;[Epub ahead of print] doi:10.1016/j.cbpb.2019.110368. |
Regulation of FXR1 by alternative splicing is required for muscle development and controls liquid-like condensates in muscle cells
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/818476 Epub:
Not Epub Abstract:
Fragile-X mental retardation autosomal homolog-1 (FXR1) is a muscle-enriched RNA-binding protein. FXR1 depletion is perinatally... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Smith JA, Curry EG, Blue RE, Roden C, Dundon SER, Rodríguez-Vargas A, Jordan DC, Chen X, Lyons SW, Crutchley J, Anderson P, Horb ME, Gladfelter AS, Giudice J. Regulation of FXR1 by alternative splicing is required for muscle development and controls liquid-like condensates in muscle cells. bioRxiv. 2019;[preprint] doi:10.1101/818476. |
POLR1B and neural crest cell anomalies in Treacher Collins syndrome type 4
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Citation:
Genet Med. 2019 Oct 24. doi: 10.1038/s41436-019-0669-9. [Epub ahead of print] Epub:
Yes Abstract:
PURPOSE: Treacher Collins syndrome (TCS) is a rare autosomal dominant mandibulofacial dysostosis, with a prevalence of 0.2-1/10... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sanchez E, Laplace-Builhé B, Mau-Them FT, Richard E, Goldenberg A, Toler TL, Guignard T, Gatinois V, Vincent M, Blanchet C, Boland A, Bihoreau MT, Deleuze JF, Olaso R, Nephi W, Lüdecke HJ, Verheij JBGM, Moreau-Lenoir F, Denoyelle F, Rivière JB, Laplanche JL, Willing M, Captier G, Apparailly F, Wieczorek D, Collet C, Djouad F, Geneviève D. POLR1B and neural crest cell anomalies in Treacher Collins syndrome type 4. Genet Med. 2019 Oct 24. doi: 10.1038/s41436-019-0669-9. [Epub ahead of print]. |
Composition dependent phase separation underlies directional flux through the nucleolus
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/809210 Epub:
Not Epub Abstract:
Intracellular bodies such as nucleoli, Cajal bodies, and various signaling assemblies, represent membraneless organelles, or... Citation Extract: Riback JA, Zhu L, Ferrolino MC, Tolbert M, Mitrea DM, Sanders DW, Wei M-T, Kriwacki RW, Brangwynne CP. Composition dependent phase separation underlies directional flux through the nucleolus. bioRxiv. 2019;[preprint] doi:10.1101/809210. |
Interleukin-6 signaling regulates hematopoietic stem cell emergence
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Citation:
Exp Mol Med. 2019 Oct 24;51(10):124. doi: 10.1038/s12276-019-0320-5 Epub:
Not Epub Abstract:
Hematopoietic stem cells (HSCs) produce all lineages of mature blood cells for the lifetime of an organism. In vertebrates,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tie R, Li H, Cai S, Liang Z, Shan W, Wang B, Tan Y, Zheng W, Huang H. Interleukin-6 signaling regulates hematopoietic stem cell emergence. Exp Mol Med. 2019 Oct 24;51(10):124. doi: 10.1038/s12276-019-0320-5. |
Loss-of-spen disturbs cardiac conduction in zebrafish mediated by impaired connexin43 function
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Citation:
Eur Heart J, 2019;40(Supplement_1):ehz746.0023. doi:10.1093/eurheartj/ehz746.0023 Epub:
Not Epub Abstract:
Genome-wide association studies identified SPLIT ENDS (SPEN) gene as an interesting candidate in the pathogenesis of heart... Organism or Cell Type:
zebrafish Citation Extract: Rattka M, Westphal S, Pott A, Kessler M, Weinmann K, Just S, Rottbauer W. Loss-of-spen disturbs cardiac conduction in zebrafish mediated by impaired connexin43 function. Eur Heart J, 2019;40(Supplement_1):ehz746.0023. doi:10.1093/eurheartj/ehz746.0023. |
Bioinformatics Screening of Genes Specific for Well-Regenerating Vertebrates Reveals c-answer, a Regulator of Brain Development and Regeneration
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Citation:
Cell Rep. 2019 Oct 22;29(4):1027-1040.e6. doi: 10.1016/j.celrep.2019.09.038 Epub:
Not Epub Abstract:
The molecular basis of higher regenerative capacity of cold-blooded animals comparing to warm-blooded ones is poorly understood... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Korotkova DD, Lyubetsky VA, Ivanova AS, Rubanov LI, Seliverstov AV, Zverkov OA, Martynova NY, Nesterenko AM, Tereshina MB, Peshkin L, Zaraisky AG. Bioinformatics Screening of Genes Specific for Well-Regenerating Vertebrates Reveals c-answer, a Regulator of Brain Development and Regeneration. Cell Rep. 2019 Oct 22;29(4):1027-1040.e6. doi: 10.1016/j.celrep.2019.09.038. |
Differential Expression of a Classic Cadherin Directs Tissue-Level Contractile Asymmetry during Neural Tube Closure
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Citation:
Dev Cell. 2019 Oct 21;51(2):158-172.e4. doi: 10.1016/j.devcel.2019.10.001 Epub:
Not Epub Abstract:
Embryos control force generation at tissue bound-aries, but how they do so remains poorly understood.Here we show how tissue-... Delivery Method:
microinjection Organism or Cell Type:
Ciona robusta (AKA C. intestinalis; ascidian) Citation Extract: Hashimoto H, Munro E. Differential Expression of a Classic Cadherin Directs Tissue-Level Contractile Asymmetry during Neural Tube Closure. Dev Cell. 2019 Oct 21;51(2):158-172.e4. doi: 10.1016/j.devcel.2019.10.001. |