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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Hypomorphic zebrafish models mimic the musculoskeletal phenotype of β4GalT7-deficient Ehlers-Danlos syndrome
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Citation:
Matrix Biol. 2019;[Epub ahead of print] doi:10.1016/j.matbio.2019.12.002 Epub:
Yes Abstract:
β4GalT7 is a transmembrane Golgi enzyme, encoded by B4GALT7, that plays a pivotal role in the proteoglycan linker region... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Delbaere S, Van Damme T, Syx D, Symoens S, Coucke P, Willaert A, Malfait F. Hypomorphic zebrafish models mimic the musculoskeletal phenotype of β4GalT7-deficient Ehlers-Danlos syndrome. Matrix Biol. 2019;[Epub ahead of print] doi:10.1016/j.matbio.2019.12.002. |
A biphasic role of non-canonical Wnt16 signaling during early anterior-posterior patterning and morphogenesis of the sea urchin embryo
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Citation:
Development. 2019 Dec 16;146(24). pii: dev168799. doi: 10.1242/dev.168799 Epub:
Not Epub Abstract:
A Wnt signaling network governs early anterior-posterior (AP) specification and patterning of the deuterostome sea urchin... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Martínez-Bartolomé M, Range RC. A biphasic role of non-canonical Wnt16 signaling during early anterior-posterior patterning and morphogenesis of the sea urchin embryo. Development. 2019 Dec 16;146(24). pii: dev168799. doi: 10.1242/dev.168799. |
The secreted BMP antagonist ERFE is required for the development of a functional circulatory system in Xenopus
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Citation:
Dev Biol. 2019 Dec 14. pii: S0012-1606(19)30366-5. doi: 10.1016/j.ydbio.2019.12.007. [Epub ahead of print] Epub:
Yes Abstract:
The hormone Erythroferrone (ERFE) is a member of the C1q/TNF-related protein family that regulates iron homeostasis through the... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Melchert J, Henningfeld KA, Richts S, Lingner T, Jonigk D, Pieler T. The secreted BMP antagonist ERFE is required for the development of a functional circulatory system in Xenopus. Dev Biol. 2019 Dec 14. pii: S0012-1606(19)30366-5. doi: 10.1016/j.ydbio.2019.12.007. [Epub ahead of print]. |
SOX19b regulates the premature neuronal differentiation of neural stem cells through EZH2-mediated histone methylation in neural tube development of zebrafish
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Citation:
Stem Cell Res Ther. 2019 Dec 16;10(1):389. doi: 10.1186/s13287-019-1495-3 Epub:
Not Epub Abstract:
OBJECTIVE: Neural tube defects (NTDs) are the most serious and common birth defects in the clinic. The SRY-related HMG box B1 (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li X, Zhou W, Li X, Gao M, Ji S, Tian W, Ji G, Du J, Hao A. SOX19b regulates the premature neuronal differentiation of neural stem cells through EZH2-mediated histone methylation in neural tube development of zebrafish. Stem Cell Res Ther. 2019 Dec 16;10(1):389. doi: 10.1186/s13287-019-1495-3. |
BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/2019.12.13.876268 Epub:
Not Epub Abstract:
Angiogenesis and lymphangiogenesis are key processes during embryogenesis as well as under physiological and pathological... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cohen B, Tempelhof H, Raz T, Oren R, Nicenboim J, Bochner F, Even R, Jelinski A, Eilam R, Ben-Dor S, Addadi Y, Golani O, Lazar S, Yaniv K, Neeman M. BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression. bioRxiv. 2019;[preprint] doi:10.1101/2019.12.13.876268. |
SCGN deficiency results in colitis susceptibility
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Citation:
Elife. 2019 Oct 30;8. pii: e49910. doi:10.7554/eLife.49910 Epub:
Not Epub Abstract:
Inflammatory bowel disease (IBD) affects 1.5-3.0 million people in the United States. IBD is genetically determined and many... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sifuentes-Dominguez LF, Li H, Llano E, Liu Z, Singla A, Patel AS, Kathania M, Khoury A, Norris N, Rios JJ, Starokadomskyy P, Park JY, Gopal P, Liu Q, Tan S, Chan L, Ross T, Harrison S, Venuprasad K, Baker LA, Jia D, Burstein E. SCGN deficiency results in colitis susceptibility. Elife. 2019 Oct 30;8. pii: e49910. doi:10.7554/eLife.49910. |
Systems genetics analysis identify calcium signalling defects as novel cause of congenital heart disease
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/2019.12.11.872424 Epub:
Not Epub Abstract:
Background: Congenital heart disease (CHD) occurs in almost 1% of newborn children and is considered a multifactorial disorder... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Izarzugaza JMG, Ellesøe SG, Doganli C, Ehlers NS, Dalgaard MD, Audain E, Dombrowsky G, Sifrim A, Wilsdon A, Thienpont B, Breckpot J, Gewillig M, Competence Network for Congenital Heart Defects, Germany, Brook JD, Hitz M-P, Larsen LA, Brunak S. Systems genetics analysis identify calcium signalling defects as novel cause of congenital heart disease. bioRxiv. 2019;[preprint] doi:10.1101/2019.12.11.872424. |
Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence
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Citation:
PLoS Pathog. 2019;15(12):e1008006. doi:10.1371/journal.ppat.1008006 Epub:
Not Epub Abstract:
Shigella flexneri is historically regarded as the primary agent of bacillary dysentery, yet the closely-related Shigella sonnei... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Torraca V, Kaforou M, Watson J, Duggan GM, Guerrero-Gutierrez H, Krokowski S, Hollinshead M, Thomas B. Clarke TB, Mostowy RJ, Tomlinson GS, Sancho-Shimizu V, Clements A, Mostowy S. Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence. PLoS Pathog. 2019;15(12):e1008006. doi:10.1371/journal.ppat.1008006. |
Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation
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Citation:
eLife. 2019;8:e51447. doi:10.7554/eLife.51447 Epub:
Not Epub Abstract:
Tcf7l2 mediates Wnt/β-Catenin signalling during development and is implicated in cancer and type-2 diabetes. The mechanisms by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Young RM, Ewan KB, Ferrer VP, Allende ML, Godovac-Zimmermann J, Dale TC, Wilson SW. Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation. eLife. 2019;8:e51447. doi:10.7554/eLife.51447. |
Neural crest cells bulldoze through the microenvironment using Aquaporin-1 to stabilize filopodia
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Citation:
Development. 2019 Dec 11. pii: dev.185231. doi: 10.1242/dev.185231. [Epub ahead of print] Epub:
Yes Abstract:
Neural crest migration requires cells to move through an environment filled with dense extracellular matrix and mesoderm to... Organism or Cell Type:
Gallus gallus (chick) Citation Extract: McLennan R, McKinney MC, Teddy JM, Morrison JA, Kasemeier-Kulesa JC, Ridenour DA, Manthe CA, Giniunaite R, Robinson M, Baker RE, Maini PK, Kulesa PM. Neural crest cells bulldoze through the microenvironment using Aquaporin-1 to stabilize filopodia. Development. 2019 Dec 11. pii: dev.185231. doi: 10.1242/dev.185231. [Epub ahead of print]. |