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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b
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Citation:
PLoS Genet. 2019 Sep 23;15(9):e1008306. doi: 10.1371/journal.pgen.1008306. [Epub ahead of print] Epub:
Yes Abstract:
During vertebrate early embryogenesis, the ventral development is directed by the ventral-to-dorsal activity gradient of the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ye D, Wang X, Wei C, He M, Wang H, Wang Y, Zhu Z, Sun Y. Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b. PLoS Genet. 2019 Sep 23;15(9):e1008306. doi: 10.1371/journal.pgen.1008306. [Epub ahead of print]. |
Cadherin switch marks germ layer formation in the diploblastic sea anemone Nematostella vectensis
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Citation:
Development. 2019 Sep 20. pii: dev.174623. doi: 10.1242/dev.174623. [Epub ahead of print] Epub:
Yes Abstract:
Morphogenesis is a shape-building process during development of multicellular organisms. During this process the establishment... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Pukhlyakova EA, Kirillova AO, Kraus YA, Zimmermann B, Technau U. Cadherin switch marks germ layer formation in the diploblastic sea anemone Nematostella vectensis. Development. 2019 Sep 20. pii: dev.174623. doi: 10.1242/dev.174623. [Epub ahead of print]. |
Hexose potentiates peptide-conjugated morpholino oligomer efficacy in cardiac muscles of dystrophic mice in an age-dependent manner
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Citation:
Mol Ther Nucl Acids. 2019 Sep 23;18:341-350. doi: 10.1016/j.omtn.2019.09.012. [Epub ahead of print] Epub:
Not Epub Abstract:
Insufficient delivery of oligonucleotides to muscle and heart remains a barrier for clinical implementation of antisense... Delivery Method:
peptide-linked Organism or Cell Type:
mice mdx Citation Extract: Han G, Gu B, Lin C, Ning H, Song J, Gao X, Moulton HM, Yin HF. Hexose potentiates peptide-conjugated morpholino oligomer efficacy in cardiac muscles of dystrophic mice in an age-dependent manner. Mol Ther Nucl Acids. 2019 Sep 23;18:341-350. doi: 10.1016/j.omtn.2019.09.012. [Epub ahead of print]. |
The gastrointestinal development ‘parts list’: transcript profiling of embryonic gut development in wildtype and Ret-deficient mice
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Citation:
bioRxiv. 2019;[preprint] doi: 10.1101/730010 Epub:
Not Epub Abstract:
The development of the gut from endodermal tissue to an organ with multiple distinct structures and functions occurs over a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chatterjee S, Nandakumar P, Auer DR, Gabriel SB, Chakravarti A. The gastrointestinal development ‘parts list’: transcript profiling of embryonic gut development in wildtype and Ret-deficient mice. bioRxiv. 2019;[preprint] doi: 10.1101/730010 . |
Neuroblast sensory quiescence depends of vascular cytoneme contacts and sensory neuronal differentiation requires initiation of blood flow
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/667519 Epub:
Not Epub Abstract:
In many organs, stem cell function depends on the communication with their niche partners. Cranial sensory neurons develop in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Taberner L, Bañón A, Alsina B. Neuroblast sensory quiescence depends of vascular cytoneme contacts and sensory neuronal differentiation requires initiation of blood flow. bioRxiv. 2019;[preprint] doi:10.1101/667519 . |
Hingepoints and neural folds reveal conserved features of primary neurulation in the zebrafish forebrain
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Citation:
bioRxiv. 2019;[preprint] doi:/10.1101/738161 Epub:
Not Epub Abstract:
Primary neurulation is the process by which the neural tube, the central nervous system precursor, is formed from the neural... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Werner JM, Negesse MY, Brooks DL, Caldwell AR, Johnson JM, Brewster R. Hingepoints and neural folds reveal conserved features of primary neurulation in the zebrafish forebrain. bioRxiv. 2019;[preprint] doi:/10.1101/738161 . |
Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles
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Citation:
Adv Funct Mater. 2019;[Epub] doi:10.1002/adfm.201906432 Epub:
Not Epub Abstract:
Phosphorodiamidate morpholino oligomers (PMOs) are oligonucleotide analogs that can be used for therapeutic modulation of pre‐... Delivery Method:
nanoparticle Organism or Cell Type:
cell culture: HeLa pLuc/705, mdx52 skeletal myotubes Citation Extract: Kuhn J, Klein PM, Al Danaf N, Nordin JZ, Reinhard S, Loy DM, Höhn M, El Andaloussi S, Lamb DC, Wagner E, Aoki Y, Lehto T, Lächelt U. Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles. Adv Funct Mater. 2019;[Epub] doi:10.1002/adfm.201906432. |
Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals
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Citation:
Nat Comm. 2019;10(1):4269. doi:10.1038/s41467-019-12263-w Epub:
Not Epub Abstract:
Embryonic development yields many different cell types in response to just a few families of inductive signals. The property of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Gentsch GE, Spruce T, Owens NDL, Smith JC. Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals. Nat Comm. 2019;10(1):4269. doi:10.1038/s41467-019-12263-w. |
Loss of Nance-Horan Syndrome b (nhsb) prevents expansion growth of retinal progenitor cells by selective up-regulation of Δ113p53
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/775171 Epub:
Not Epub Abstract:
The regulation of cell cycle progression and differentiation in retinal progenitor cells is a fundamental feature controlling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish, Xenopus tropicalis Citation Extract: Vorster PJ, Ojumu J, Dickinson AJG, Walsh GS. Loss of Nance-Horan Syndrome b (nhsb) prevents expansion growth of retinal progenitor cells by selective up-regulation of Δ113p53. bioRxiv. 2019;[preprint] doi:10.1101/775171 . |
The investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/767459 Epub:
Not Epub Abstract:
pVHL is a tumor suppressor. The lack of its function leads to various tumors, among which ccRCC (clear cell renal cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kim HR, Santhakumar K, Markham E, Baldera D, Bryant HE, El-Khamisy SF, van Eeden FJM. The investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish. bioRxiv. 2019;[preprint] doi:10.1101/767459. |