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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Whole-Exome Sequencing Identifies Damaging de novo Variants in Anencephalic Cases

Authors:
Wang L, Ren A, Tian T, Li N, Cao X, Zhang P, Jin L, Li Z, Shen Y, Zhang B, Finnell RH, Lei Y
Citation:
Front Neurosci. 2019;13:1285. doi:10.3389/fnins.2019.01285
Epub:
Not Epub
Abstract:
Background: Anencephaly is a lethal neural tube defect (NTD). Although variants in several genes have been implicated in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang L, Ren A, Tian T, Li N, Cao X, Zhang P, Jin L, Li Z, Shen Y, Zhang B, Finnell RH, Lei Y. Whole-Exome Sequencing Identifies Damaging de novo Variants in Anencephalic Cases. Front Neurosci. 2019;13:1285. doi:10.3389/fnins.2019.01285.

Effects of spinetoram on the developmental toxicity and immunotoxicity of zebrafish

Authors:
Cheng B, Zhang H, Jia K, Li E, Zhang S, Yu H, Cao Z, Xiong G, Hu C, Lu H
Citation:
Fish Shellfish Immunol. 2019 Nov 28. pii: S1050-4648(19)31109-X. doi: 10.1016/j.fsi.2019.11.066. [Epub ahead of print]
Epub:
Yes
Abstract:
Our study investigated the effects of spinetoram on the developmental toxicity and immunotoxicity of zebrafish. 10 h post-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cheng B, Zhang H, Jia K, Li E, Zhang S, Yu H, Cao Z, Xiong G, Hu C, Lu H. Effects of spinetoram on the developmental toxicity and immunotoxicity of zebrafish. Fish Shellfish Immunol. 2019 Nov 28. pii: S1050-4648(19)31109-X. doi: 10.1016/j.fsi.2019.11.066. [Epub ahead of print].

Modulation of RECK levels in Xenopus A6 cells: effects on MT1-MMP, MMP-2 and pERK levels

Authors:
Willson JA, Bork BS, Muir CA, Damjanovski S
Citation:
J Biol Res (Thessaloniki). 2019;26:16. doi:10.1186/s40709-019-0108-8
Epub:
Not Epub
Abstract:
Background: MT1-MMP is a cell-surface enzyme whose regulation of pro-MMP-2 and ERK activation position it as a key facilitator...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: Xenopus A6 cells
Citation Extract:
Willson JA, Bork BS, Muir CA, Damjanovski S. Modulation of RECK levels in Xenopus A6 cells: effects on MT1-MMP, MMP-2 and pERK levels. J Biol Res (Thessaloniki). 2019;26:16. doi:10.1186/s40709-019-0108-8.

Dkk1 Controls Cell-Cell Interaction through Regulation of Non-nuclear β-Catenin Pools

Authors:
Johansson M, Giger FA, Fielding T, Houart C
Citation:
Dev Cell. 2019 Nov 26. pii: S1534-5807(19)30904-9. doi: 10.1016/j.devcel.2019.10.026. [Epub ahead of print]
Epub:
Yes
Abstract:
Dickkopf-1 (Dkk1) is a secreted Wnt antagonist with a well-established role in head induction during development. Numerous...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Johansson M, Giger FA, Fielding T, Houart C. Dkk1 Controls Cell-Cell Interaction through Regulation of Non-nuclear β-Catenin Pools. Dev Cell. 2019 Nov 26. pii: S1534-5807(19)30904-9. doi: 10.1016/j.devcel.2019.10.026. [Epub ahead of print].

Characterizing renal involvement in Hermansky-Pudlak Syndrome in a zebrafish model

Authors:
Schenk H, Müller-Deile J, Schroder P, Bolaños-Palmieri P, Beverly-Staggs L, White R, Bräsen JH, Haller H, Schiffer M
Citation:
Sci Rep. 2019 Nov 27;9(1):17718. doi: 10.1038/s41598-019-54058-5
Epub:
Not Epub
Abstract:
Hermansky-Pudlak Syndrome (HPS) is a rare disease caused by mutations in the genes coding for various HPS proteins. HPS...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schenk H, Müller-Deile J, Schroder P, Bolaños-Palmieri P, Beverly-Staggs L, White R, Bräsen JH, Haller H, Schiffer M. Characterizing renal involvement in Hermansky-Pudlak Syndrome in a zebrafish model. Sci Rep. 2019 Nov 27;9(1):17718. doi: 10.1038/s41598-019-54058-5.

Embryo microinjection of the lecithotrophic sea urchin Heliocidaris erythrogramma

Authors:
Edgar A, Byrne M, Wray GA
Citation:
J Biol Methods. 2019 Sep 17;6(3):e119. doi: 10.14440/jbm.2019.292. eCollection 2019
Epub:
Not Epub
Abstract:
Microinjection is a common embryological technique used for many types of experiments, including lineage tracing, manipulating...
Delivery Method:
microinjection
Organism or Cell Type:
Heliocidaris erythrogramma (sea urchin)
Citation Extract:
Edgar A, Byrne M, Wray GA. Embryo microinjection of the lecithotrophic sea urchin Heliocidaris erythrogramma. J Biol Methods. 2019 Sep 17;6(3):e119. doi: 10.14440/jbm.2019.292. eCollection 2019.

PDGF signaling from pharyngeal pouches promotes arch artery morphogenesis

Authors:
Mao A, Zhang M, Liu J, Cao Y, Wang Q
Citation:
J Genet Genom. 2019;[epub ahead of print] doi:10.1016/j.jgg.2019.11.004
Epub:
Yes
Abstract:
The great vessels of the heart originate from the pharyngeal arch arteries (PAAs). Anomalies of the PAAs often occur together...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mao A, Zhang M, Liu J, Cao Y, Wang Q. PDGF signaling from pharyngeal pouches promotes arch artery morphogenesis. J Genet Genom. 2019;[epub ahead of print] doi:10.1016/j.jgg.2019.11.004.

Association of Rare Genetic Variants in Opioid Receptors with Tourette Syndrome

Authors:
Depienne C, Ciura S, Trouillard O, Bouteiller D, Leitão E, Nava C, Keren B, Marie Y, Guegan J, Forlani S, Brice A, Anheim M, Agid Y, Krack P, Damier P, Viallet F, Houeto J-L, Durif F, Vidailhet M, Worbe Y, Roze E, Kabashi E, Hartmann A
Citation:
Tremor Other Hyperkinet Mov. 2019;9. doi:10.7916/tohm.v0.693
Epub:
Not Epub
Abstract:
Background: Genes involved in Tourette syndrome (TS) remain largely unknown. We aimed to identify genetic factors contributing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Depienne C, Ciura S, Trouillard O, Bouteiller D, Leitão E, Nava C, Keren B, Marie Y, Guegan J, Forlani S, Brice A, Anheim M, Agid Y, Krack P, Damier P, Viallet F, Houeto J-L, Durif F, Vidailhet M, Worbe Y, Roze E, Kabashi E, Hartmann A. Association of Rare Genetic Variants in Opioid Receptors with Tourette Syndrome. Tremor Other Hyperkinet Mov. 2019;9. doi:10.7916/tohm.v0.693.

Genetic risk of cholangiocarcinoma is linked to the autophagy gene ATG7

Authors:
Greer SU, Ogmundsdottir MH, Chen J, Lau BT, Delacruz RGC, Sandoval IT, Kristjansdottir S, Jones DA, Haslem DS, Romero R, Fulde G, Bell JM, Jonasson JG, Steingrimsson E, Ji HP, Nadauld LD
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/836767
Epub:
Not Epub
Abstract:
Cholangiocarcinoma is an aggressive cancer originating from the bile duct. Although cholangiocarcinoma does occur in families,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Greer SU, Ogmundsdottir MH, Chen J, Lau BT, Delacruz RGC, Sandoval IT, Kristjansdottir S, Jones DA, Haslem DS, Romero R, Fulde G, Bell JM, Jonasson JG, Steingrimsson E, Ji HP, Nadauld LD. Genetic risk of cholangiocarcinoma is linked to the autophagy gene ATG7. bioRxiv. 2019;[preprint] doi:10.1101/836767 .

Uncoupling splicing from transcription using antisense oligonucleotides reveals a dual role for I exon donor splice sites in antibody class switching

Authors:
Marchalot A, Ashi MO, Lambert J-M, Srour N, Delpy L, Le Pennec S
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/850867
Epub:
Not Epub
Abstract:
Class switch recombination (CSR) changes antibody isotype by replacing Cμ constant exons with different constant exons located...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: mouse splenic B cells
Citation Extract:
Marchalot A, Ashi MO, Lambert J-M, Srour N, Delpy L, Le Pennec S. Uncoupling splicing from transcription using antisense oligonucleotides reveals a dual role for I exon donor splice sites in antibody class switching. bioRxiv. 2019;[preprint] doi:10.1101/850867.

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