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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Programmed cell death along the midline axis patterns ipsilaterality in gastrulation
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Citation:
Science. 2020;367(6474):197-200. doi:10.1126/science.aaw2731 Epub:
Not Epub Abstract:
Bilateral symmetry is the predominant body plan in the animal kingdom. Cells on the left and right sides remain... Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Maya-Ramos L, Mikawa T. Programmed cell death along the midline axis patterns ipsilaterality in gastrulation. Science. 2020;367(6474):197-200. doi:10.1126/science.aaw2731 . |
NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.01.08.898437 Epub:
Not Epub Abstract:
Terminal selectors are transcription factors that control the morphological, physiological and molecular features that... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Tournière O, Dolan D, Richards GS, Sunagar K, Columbus-Shenkar YY, Moran Y, Rentzsch F. NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis. bioRxiv. 2020;[preprint] doi:10.1101/2020.01.08.898437. |
Dual role of Jam3b in early hematopoietic and vascular development
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Citation:
Development. 2020;147(1):dev181040. doi:10.1242/dev.181040 Epub:
Not Epub Abstract:
In order to efficiently derive hematopoietic stem cells (HSCs) from pluripotent precursors, it is crucial to understand how... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kobayashi I, Kobayashi-Sun J, Hirakawa Y, Ouchi M, Yasuda K, Kamei H, Fukuhara S, Yamaguchi M. Dual role of Jam3b in early hematopoietic and vascular development. Development. 2020;147(1):dev181040. doi:10.1242/dev.181040 . |
Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21
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Citation:
Cell Rep. 2020;30(1):124-36.e4. doi:10.1016/j.celrep.2019.12.015 Epub:
Not Epub Abstract:
Increased glycolytic metabolism recently emerged as an essential process driving host defense against Mycobacterium... Delivery Method:
Lipofectamine 2000 Organism or Cell Type:
cell culture: bone-marrow-derived macrophages (BMDMs) Citation Extract: Hackett EE, Charles-Messance H, O’Leary SM, Gleeson LE, Muñoz-Wolf N, Case S, Wedderburn A, Johnston DGW, Williams MA, Smyth A, Ouimet M, Moore KJ, Lavelle EC, Corr SC, Gordon SV, Keane J, Sheedy FJ. Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21. Cell Rep. 2020;30(1):124-36.e4. doi:10.1016/j.celrep.2019.12.015. |
U1 snRNP regulates cancer cell migration and invasion in vitro
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Citation:
Nat Commun. 2020;11:1. doi:10.1038/s41467-019-13993-7 Epub:
Not Epub Abstract:
Stimulated cells and cancer cells have widespread shortening of mRNA 3’-untranslated regions (3’UTRs) and switches to shorter... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HeLa, A549, MCF-7 & MDA-MB-231 Citation Extract: Oh J, Venters CC, Di C, Pinto AM, Wan L, Younis I, Cai Z, Arai C, So BR, Duan J, Dreyfuss G. U1 snRNP regulates cancer cell migration and invasion in vitro. Nat Commun. 2020;11:1. doi:10.1038/s41467-019-13993-7. |
Glycogen storage in a zebrafish Pompe disease model is reduced by 3-BrPA treatment
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Citation:
Biochim Biophys Acta Mol Basis Dis. 2020;[epub ahead of print] doi:10.1016/j.bbadis.2020.165662 Epub:
Yes Abstract:
Pompe disease (PD) is an autosomal recessive muscular disorder caused by deficiency of the glycogen hydrolytic enzyme acid α-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bragato C, Carra S, Blasevich F, Salerno F, Brix A, Bassi A, Beltrame M, Cotelli F, Maggi L, Mantegazza R, Mora M. Glycogen storage in a zebrafish Pompe disease model is reduced by 3-BrPA treatment. Biochim Biophys Acta Mol Basis Dis. 2020;[epub ahead of print] doi:10.1016/j.bbadis.2020.165662. |
Disrupted ER membrane protein complex-mediated topogenesis drives congenital neural crest defects
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Citation:
J Clin Invest. 2020 Jan 6. pii: 129308. doi: 10.1172/JCI129308. [Epub ahead of print] Epub:
Yes Abstract:
Multipass membrane proteins have a myriad of functions, including transduction of cell-cell signals, ion transport, and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Marquez J, Criscione J, Charney RM, Prasad MS, Hwang WY, Mis EK, García-Castro MI, Khokha MK. Disrupted ER membrane protein complex-mediated topogenesis drives congenital neural crest defects. J Clin Invest. 2020 Jan 6. pii: 129308. doi: 10.1172/JCI129308. [Epub ahead of print]. |
march5 Governs the Convergence and Extension Movement for Organization of the Telencephalon and Diencephalon in Zebrafish Embryos
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Citation:
Mol Cells. 2020 Jan 7. doi: 10.14348/molcells.2019.0210. [Epub ahead of print] Epub:
Yes Abstract:
MARCH5 is a RING finger E3 ligase involved in mitochondrial integrity, cellular protein homeostasis, and the regulation of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jung J, Choi I, Ro H, Huh TL, Choe J, Rhee M. march5 Governs the Convergence and Extension Movement for Organization of the Telencephalon and Diencephalon in Zebrafish Embryos. Mol Cells. 2020 Jan 7. doi: 10.14348/molcells.2019.0210. [Epub ahead of print]. |
Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer’s model of adult zebrafish brain
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Citation:
PLoS Biol.2020:18(1):e3000585. doi:10.1371/journal.pbio.3000585 Epub:
Not Epub Abstract:
It was recently suggested that supplying the brain with new neurons could counteract Alzheimer’s disease (AD). This provocative... Delivery Method:
i.c.v. microinjection Organism or Cell Type:
zebrafish Citation Extract: Bhattarai P, Cosacak MI, Mashkaryan V, Demir S, Popova SD, Govindarajan N, Brandt K, Zhang Y, Chang W, Ampatzis K, Kizil C. Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer’s model of adult zebrafish brain. PLoS Biol.2020:18(1):e3000585. doi:10.1371/journal.pbio.3000585. |
Vezf1 regulates cardiac structure and contractile function
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Citation:
EBioMed. 2020;51:102608. doi:10.1016/j.ebiom.2019.102608 Epub:
Not Epub Abstract:
Background: Vascular endothelial zinc finger 1 (Vezf1) is a transcription factor previously shown to regulate vasculogenesis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Paavola J, Alakoski T, Ulvila J, Kilpiö T, Sirén J, Perttunen S, Narumanchi S, Wang H, Lin R, Porvari K, Junttila J, Huikuri H, Immonen K, Lakkisto P, Magga J, Tikkanen I, Kerkelä R. Vezf1 regulates cardiac structure and contractile function. EBioMed. 2020;51:102608. doi:10.1016/j.ebiom.2019.102608. |