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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Left-right asymmetric heart jogging increases the robustness of dextral heart looping in zebrafish

Authors:
Grimes DT, Patterson VL, Luna-Arvizu G, Schottenfeld-Roames J, Irons ZH, Burdine RD
Citation:
Dev Biol. 2019 Nov 20. pii: S0012-1606(19)30254-4. doi: 10.1016/j.ydbio.2019.11.012. [Epub ahead of print]
Epub:
Yes
Abstract:
Building a left-right (L-R) asymmetric organ requires asymmetric information. This comes from various sources, including...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Grimes DT, Patterson VL, Luna-Arvizu G, Schottenfeld-Roames J, Irons ZH, Burdine RD. Left-right asymmetric heart jogging increases the robustness of dextral heart looping in zebrafish. Dev Biol. 2019 Nov 20. pii: S0012-1606(19)30254-4. doi: 10.1016/j.ydbio.2019.11.012. [Epub ahead of print].

Scavenger Receptor Cysteine-Rich domains of Lysyl Oxidase-Like2 regulate endothelial ECM and angiogenesis through non-catalytic scaffolding mechanisms

Authors:
Umana-Diaz C, Pichol-Thievend C, Marchand MF, Atlas Y, Salza R, Malbouyres M, Barret A, Teillon J, Ardidie-Robouant C, Ruggiero F, Monnot C, Girard P, Guilluy C, Ricard-Blum S, Germain S, Muller L
Citation:
Matrix Biol. 2019 Nov 20. pii: S0945-053X(19)30390-7. doi: 10.1016/j.matbio.2019.11.003. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Lysyl oxidases are major actors of microenvironment and extracellular matrix (ECM) remodeling. These cross-linking enzymes are...
Organism or Cell Type:
zebrafish
Citation Extract:
Umana-Diaz C, Pichol-Thievend C, Marchand MF, Atlas Y, Salza R, Malbouyres M, Barret A, Teillon J, Ardidie-Robouant C, Ruggiero F, Monnot C, Girard P, Guilluy C, Ricard-Blum S, Germain S, Muller L. Scavenger Receptor Cysteine-Rich domains of Lysyl Oxidase-Like2 regulate endothelial ECM and angiogenesis through non-catalytic scaffolding mechanisms. Matrix Biol. 2019 Nov 20. pii: S0945-053X(19)30390-7. doi: 10.1016/j.matbio.2019.11.003. [Epub ahead of print].

Gata is ubiquitously required for the earliest zygotic gene transcription in the ascidian embryo

Authors:
Imai KS, Kobayashi K, Kari W, Rothbächer U, Ookubo N, Oda-Ishii I, Satou Y
Citation:
Dev Biol. 2019 Nov 18. pii: S0012-1606(19)30466-X. doi: 10.1016/j.ydbio.2019.11.009. [Epub ahead of print]
Epub:
Yes
Abstract:
In ascidian embryos, the earliest transcription from the zygotic genome begins between the 8-cell and 16-cell stages. Gata.a, a...
Organism or Cell Type:
ascidian
Citation Extract:
Imai KS, Kobayashi K, Kari W, Rothbächer U, Ookubo N, Oda-Ishii I, Satou Y. Gata is ubiquitously required for the earliest zygotic gene transcription in the ascidian embryo. Dev Biol. 2019 Nov 18. pii: S0012-1606(19)30466-X. doi: 10.1016/j.ydbio.2019.11.009. [Epub ahead of print].

Selenomethionine exposure affects chondrogenic differentiation and bone formation in Japanese medaka (Oryzias latipes)

Authors:
Wang H, Chen H, Chernick M, Li D, Ying G-G, Yang J, Zheng N, Xie L, Hinton DE, Dong W
Citation:
J Haz Mater. 2019;[Epub ahead of print] doi:10.1016/j.jhazmat.2019.121720
Epub:
Yes
Abstract:
Excess selenium entering the aquatic environment from anthropogenic activities has been associated with developmental...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Wang H, Chen H, Chernick M, Li D, Ying G-G, Yang J, Zheng N, Xie L, Hinton DE, Dong W. Selenomethionine exposure affects chondrogenic differentiation and bone formation in Japanese medaka (Oryzias latipes). J Haz Mater. 2019;[Epub ahead of print] doi:10.1016/j.jhazmat.2019.121720.

Wnt proteins can direct planar cell polarity in vertebrate ectoderm

Authors:
Chu C-W, Sokol SY
Citation:
eLife. 2016;5:e16463 doi:10.7554/eLife.16463.001
Epub:
Not Epub
Abstract:
The coordinated orientation of cells across the tissue plane, known as planar cell polarity (PCP), is manifested by the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chu C-W, Sokol SY. Wnt proteins can direct planar cell polarity in vertebrate ectoderm. eLife. 2016;5:e16463 doi:10.7554/eLife.16463.001.

Proteasome subunit PSMC3 variants cause neurosensory syndrome combining deafness and cataract due to proteotoxic stress

Authors:
Kröll-Hermi A, Ebstein F, Stoetzel C, Geoffroy V, Schaefer E, Scheidecker S, Bär S, Takamiya M, Kawakami K, Zieba BA, Studer F, Pelletier V, Speeg-Schatz C, Laugel V, Lipsker D, Sandron F, McGinn S, Boland A, Deleuze J-F, Kuhn L, Chicher J, Hammann P, Friant S, Etard C, Krüger E, Muller J, Strähle U, Dollfus H
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/836015
Epub:
Not Epub
Abstract:
Whole-genome sequencing was performed on patients with severe deafness and early-onset cataracts as part of a neurological,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kröll-Hermi A, Ebstein F, Stoetzel C, Geoffroy V, Schaefer E, Scheidecker S, Bär S, Takamiya M, Kawakami K, Zieba BA, Studer F, Pelletier V, Speeg-Schatz C, Laugel V, Lipsker D, Sandron F, McGinn S, Boland A, Deleuze J-F, Kuhn L, Chicher J, Hammann P, Friant S, Etard C, Krüger E, Muller J, Strähle U, Dollfus H. Proteasome subunit PSMC3 variants cause neurosensory syndrome combining deafness and cataract due to proteotoxic stress. bioRxiv. 2019;[preprint] doi:10.1101/836015.

Maternal miR-202-5p is required for zebrafish primordial germ cell migration by protecting small GTPase Cdc42

Authors:
Jin Y, Liu W, Xiang Y, Zhang W, Zhang H, Jia K, Yi M
Citation:
J Mol Cell Biol. 2019 Nov 19. pii: mjz103. doi: 10.1093/jmcb/mjz103. [Epub ahead of print]
Epub:
Yes
Abstract:
In many lower animals, germ cell formation, migration and maintenance depend on maternally provided determinants in germ plasm...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jin Y, Liu W, Xiang Y, Zhang W, Zhang H, Jia K, Yi M. Maternal miR-202-5p is required for zebrafish primordial germ cell migration by protecting small GTPase Cdc42. J Mol Cell Biol. 2019 Nov 19. pii: mjz103. doi: 10.1093/jmcb/mjz103. [Epub ahead of print].

The effect of muscle glycogen phosphorylase (Pygm) knockdown on zebrafish morphology

Authors:
Migocka-Patrzałek M, Lewicka A, Elias M, Daczewska M
Citation:
Int J Biochem Cell Biol. 2019 Nov 17:105658. doi: 10.1016/j.biocel.2019.105658. [Epub ahead of print]
Epub:
Yes
Abstract:
Muscle glycogen phosphorylase (PYGM) is a key enzyme in the first step of glycogenolysis. Mutation in the PYGM gene leads to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Migocka-Patrzałek M, Lewicka A, Elias M, Daczewska M. The effect of muscle glycogen phosphorylase (Pygm) knockdown on zebrafish morphology. Int J Biochem Cell Biol. 2019 Nov 17:105658. doi: 10.1016/j.biocel.2019.105658. [Epub ahead of print].

Spreading of a virulence lipid into host membranes promotes mycobacterial pathogenesis

Authors:
Cambier CJ, Banik S, Buonomo JA, Bertozzi C
Citation:
bioRxiv. 2019;[preprint] doi: https://doi.org/10.1101/845081
Epub:
Not Epub
Abstract:
Several lipids of the pathogen Mycobacterium tuberculosis are known to promote virulence at various stages of disease. However...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cambier CJ, Banik S, Buonomo JA, Bertozzi C. Spreading of a virulence lipid into host membranes promotes mycobacterial pathogenesis. bioRxiv. 2019;[preprint] doi: https://doi.org/10.1101/845081 .

Apcdd1 is a dual BMP/Wnt inhibitor in the developing nervous system and skin

Authors:
Vonica A, Bhat N, Phan K, Guo J, Iancu L, Weber JA, Karger A, Cain JW, Wang ECE, DeStefano GM, O’Donnell-Luria AH, Christiano AM, Riley B, Butler SJ, Luria V
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/843714
Epub:
Not Epub
Abstract:
Animal development and homeostasis depend on precise temporal and spatial intercellular signaling. Components shared between...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish, Xenopus laevis
Citation Extract:
Vonica A, Bhat N, Phan K, Guo J, Iancu L, Weber JA, Karger A, Cain JW, Wang ECE, DeStefano GM, O’Donnell-Luria AH, Christiano AM, Riley B, Butler SJ, Luria V. Apcdd1 is a dual BMP/Wnt inhibitor in the developing nervous system and skin. bioRxiv. 2019;[preprint] doi:10.1101/843714 .

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