You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Biphasic Role of Tgf-β Signaling during Müller Glia Reprogramming and Retinal Regeneration in Zebrafish

Authors:
Sharma P, Gupta S, Chaudhary M, Mitra S, Chawla B, Khursheed MA, Saran NK, Ramachandran R
Citation:
iScience. 2020 Jan 7;23(2):100817. doi: 10.1016/j.isci.2019.100817. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Tgf-β signaling is a major antiproliferative pathway governing different biological functions, including cellular reprogramming...
Link:
https://www.sciencedirect.com/science/article/pii/S2589004219305632
Delivery Method:
injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Sharma P, Gupta S, Chaudhary M, Mitra S, Chawla B, Khursheed MA, Saran NK, Ramachandran R. Biphasic Role of Tgf-β Signaling during Müller Glia Reprogramming and Retinal Regeneration in Zebrafish. iScience. 2020 Jan 7;23(2):100817. doi: 10.1016/j.isci.2019.100817. [Epub ahead of print].

The regulatory proteins DSCR6 and Ezh2 oppositely regulate Stat3 transcriptional activity in mesoderm patterning during Xenopus development

Authors:
Loreti M, Shi DL, Carron C
Citation:
J Biol Chem. 2020;295, 2724-2735. doi: 10.1074/jbc.RA119.010719.
Epub:
Not Epub
Abstract:
Embryonic cell fate specification and axis patterning requires integration of several signaling pathways that orchestrate...
Link:
https://www.jbc.org/content/early/2020/01/29/jbc.RA119.010719.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Loreti M, Shi DL, Carron C. The regulatory proteins DSCR6 and Ezh2 oppositely regulate Stat3 transcriptional activity in mesoderm patterning during Xenopus development. J Biol Chem. 2020;295, 2724-2735. doi: 10.1074/jbc.RA119.010719. .

Greb1 is required for axial elongation and segmentation in vertebrate embryos

Authors:
Prajapati RS, Mitter R, Vezzaro A, Ish-Horowicz D
Citation:
Biol Open. 2020 Jan 27. pii: bio.047290. doi: 10.1242/bio.047290. [Epub ahead of print]
Epub:
Yes
Abstract:
During vertebrate embryonic development, the formation of axial structures is driven by a population of stem-like cells that...
Link:
https://bio.biologists.org/content/early/2020/01/17/bio.047290.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prajapati RS, Mitter R, Vezzaro A, Ish-Horowicz D. Greb1 is required for axial elongation and segmentation in vertebrate embryos. Biol Open. 2020 Jan 27. pii: bio.047290. doi: 10.1242/bio.047290. [Epub ahead of print].

Morpholino Target Molecular Properties Affect the Swelling Process of Oligomorpholino-Functionalized Responsive Hydrogels

Authors:
Parelius Jonášová E, Stokke BT
Citation:
Polymers (Basel). 2020 Jan 26;12(2). pii: E268. doi: 10.3390/polym12020268
Epub:
Not Epub
Abstract:
Responsive hydrogels featuring DNA as a functional unit are attracting increasing interest due to combination of versatility...
Link:
https://www.mdpi.com/2073-4360/12/2/268
Citation Extract:
Parelius Jonášová E, Stokke BT. Morpholino Target Molecular Properties Affect the Swelling Process of Oligomorpholino-Functionalized Responsive Hydrogels. Polymers (Basel). 2020 Jan 26;12(2). pii: E268. doi: 10.3390/polym12020268.

Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway

Authors:
Sun X, Zhou Y, Zhang R, Wang Z, Xu M, Zhang D, Huang J, Luo F, Li F, Ni Z, Zhou S, Chen H, Chen S, Chen L, Du X, Chen B, Huang H, Liu P, Yin L, Qiu J, Chen D, Deng C, Xie Y, Luo L, Chen L
Citation:
Nat Comm. 2020;11(1):479 doi:10.1038/s41467-019-14169-z
Epub:
Not Epub
Abstract:
Congenital scoliosis (CS) is a complex genetic disorder characterized by vertebral malformations. The precise etiology of CS is...
Link:
https://www.nature.com/articles/s41467-019-14169-z
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun X, Zhou Y, Zhang R, Wang Z, Xu M, Zhang D, Huang J, Luo F, Li F, Ni Z, Zhou S, Chen H, Chen S, Chen L, Du X, Chen B, Huang H, Liu P, Yin L, Qiu J, Chen D, Deng C, Xie Y, Luo L, Chen L. Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway. Nat Comm. 2020;11(1):479 doi:10.1038/s41467-019-14169-z.

Hmx3a does not require its homeodomain for its essential functions in spinal cord, ear and lateral line development

Authors:
England SJ, Cerda GA, Kowalchuk AM, Sorice T, Grieb GM, Lewis KE
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.01.23.917468
Epub:
Not Epub
Abstract:
Homeodomain-containing transcription factors have crucial functions in most aspects of cellular function and embryonic...
Link:
https://www.biorxiv.org/content/10.1101/2020.01.23.917468v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
England SJ, Cerda GA, Kowalchuk AM, Sorice T, Grieb GM, Lewis KE. Hmx3a does not require its homeodomain for its essential functions in spinal cord, ear and lateral line development. bioRxiv. 2020;[preprint] doi:10.1101/2020.01.23.917468.

A Novel Recessive TNNT1 Congenital Core-Rod Myopathy in French Canadians

Authors:
Pellerin D, Aykanat A, Ellezam B, Troiano EC, Karamchandani J, Dicaire MJ, Petitclerc M, Robertson R, Allard-Chamard X, Brunet D, Konersman CG, Mathieu J, Warman Chardon J, Gupta VA, Beggs AH, Brais B, Chrestian N
Citation:
Ann Neurol. 2020 Jan 22. doi: 10.1002/ana.25685. [Epub ahead of print]
Epub:
Yes
Abstract:
OBJECTIVE: Recessive null variants of the slow skeletal muscle troponin T1 (TNNT1) gene are a rare cause of nemaline myopathy...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1002/ana.25685
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pellerin D, Aykanat A, Ellezam B, Troiano EC, Karamchandani J, Dicaire MJ, Petitclerc M, Robertson R, Allard-Chamard X, Brunet D, Konersman CG, Mathieu J, Warman Chardon J, Gupta VA, Beggs AH, Brais B, Chrestian N. A Novel Recessive TNNT1 Congenital Core-Rod Myopathy in French Canadians. Ann Neurol. 2020 Jan 22. doi: 10.1002/ana.25685. [Epub ahead of print].

Stepwise polarisation of developing bilayered epidermis is mediated by aPKC and E-cadherin in zebrafish

Authors:
Arora P, Dongre S, Raman R, Sonawane M
Citation:
eLife. 2020;9:e49064. doi:10.7554/eLife.49064
Epub:
Not Epub
Abstract:
The epidermis, a multilayered epithelium, surrounds and protects the vertebrate body. It develops from a bilayered epithelium...
Link:
https://elifesciences.org/articles/49064
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Arora P, Dongre S, Raman R, Sonawane M. Stepwise polarisation of developing bilayered epidermis is mediated by aPKC and E-cadherin in zebrafish. eLife. 2020;9:e49064. doi:10.7554/eLife.49064.

The gap junction protein Connexin 43 controls multiple aspects of cranial neural crest cell development

Authors:
Jourdeuil K, Taneyhill LA
Citation:
J Cell Sci. 2020;[Epub ahead of print] doi:10.1242/jcs.235440
Epub:
Not Epub
Abstract:
Gap junctions are intercellular channels between cells that facilitate cell-cell communication. Connexin 43 (Cx43), the...
Link:
https://jcs.biologists.org/content/early/2020/01/20/jcs.235440
Organism or Cell Type:
Gallus gallus (chick) cultures and in vivo
Citation Extract:
Jourdeuil K, Taneyhill LA. The gap junction protein Connexin 43 controls multiple aspects of cranial neural crest cell development. J Cell Sci. 2020;[Epub ahead of print] doi:10.1242/jcs.235440.

Coupling of dynamic microtubules to F-actin by Fmn2 regulates chemotaxis of neuronal growth cones

Authors:
Kundu T, Dutta P, Nagar D, Maiti S, Ghose A
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.01.18.911131
Epub:
Not Epub
Abstract:
Dynamic co-regulation of the actin and microtubule subsystems enables the highly precise and adaptive remodeling of the...
Link:
https://www.biorxiv.org/content/10.1101/2020.01.18.911131v1
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: primary Gallus gallus (chick) neurons
Citation Extract:
Kundu T, Dutta P, Nagar D, Maiti S, Ghose A. Coupling of dynamic microtubules to F-actin by Fmn2 regulates chemotaxis of neuronal growth cones. bioRxiv. 2020;[preprint] doi:10.1101/2020.01.18.911131.

Pages