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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Regeneration of Xenopus laevis spinal cord requires Sox2/3 expressing cells
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Citation:
Dev Biol. 2015 Dec 15;408(2):229-43. doi: 10.1016/j.ydbio.2015.03.009. Epub 2015 Mar 19 Epub:
Not Epub Abstract:
Spinal cord regeneration is very inefficient in humans, causing paraplegia and quadriplegia. Studying model organisms that can... Delivery Method:
injection then electroporation Organism or Cell Type:
Xenopus laevis Citation Extract: Muñoz R, Edwards-Faret G, Moreno M, Zuñiga N, Cline H, Larraín J. Regeneration of Xenopus laevis spinal cord requires Sox2/3 expressing cells. Dev Biol. 2015 Dec 15;408(2):229-43. doi: 10.1016/j.ydbio.2015.03.009. Epub 2015 Mar 19. |
Molecular mechanism of CHRDL1-mediated X-linked megalocornea in humans and in Xenopus model
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Citation:
Hum Mol Genet. 2015 Jun 1;24(11):3119-32. doi: 10.1093/hmg/ddv063. Epub 2015 Feb 23 Epub:
Not Epub Abstract:
Chordin-Like 1 (CHRDL1) mutations cause non-syndromic X-linked megalocornea (XMC) characterized by enlarged anterior eye... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Pfirrmann T, Emmerich D, Ruokonen P, Quandt D, Buchen R, Fischer-Zirnsak B, Hecht J, Krawitz P, Meyer P, Klopocki E, Stricker S, Lausch E, Seliger B, Hollemann T, Reinhard T, Auw-Haedrich C, Zabel B, Hoffmann K, Villavicencio-Lorini P. Molecular mechanism of CHRDL1-mediated X-linked megalocornea in humans and in Xenopus model. Hum Mol Genet. 2015 Jun 1;24(11):3119-32. doi: 10.1093/hmg/ddv063. Epub 2015 Feb 23. |
Characterization of cGAS homologs in innate and adaptive mucosal immunities in zebrafish gives evolutionary insights into cGAS-STING pathway
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Citation:
FASEB J. 2020 Apr 14. doi: 10.1096/fj.201902833R. [Epub ahead of print] Epub:
Yes Abstract:
Cyclic GMP-AMP synthase (cGAS) is one of the most-characterized cytoplasmic DNA sensors in humans and other mammals. However,... Citation Extract: Liu ZF, Ji JF, Jiang XF, Shao T, Fan DD, Jiang XH, Lin AF, Xiang LX, Shao JZ. Characterization of cGAS homologs in innate and adaptive mucosal immunities in zebrafish gives evolutionary insights into cGAS-STING pathway. FASEB J. 2020 Apr 14. doi: 10.1096/fj.201902833R. [Epub ahead of print]. |
Analysis of mucolipidosis II/III GNPTAB missense mutations identifies domains of UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase involved in catalytic function and lysosomal enzyme recognition
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Citation:
J Biol Chem. 2015 Jan 30;290(5):3045-56. doi: 10.1074/jbc.M114.612507. Epub 2014 Dec 11 Epub:
Not Epub Abstract:
UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase tags newly synthesized lysosomal enzymes with mannose 6-phosphate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Qian Y, van Meel E, Flanagan-Steet H, Yox A, Steet R, Kornfeld S. Analysis of mucolipidosis II/III GNPTAB missense mutations identifies domains of UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase involved in catalytic function and lysosomal enzyme recognition. J Biol Chem. 2015 Jan 30;290(5):3045-56. doi: 10.1074/jbc.M114.612507. Epub 2014 Dec 11. |
RIG-I specifically mediates group II type I IFN activation in nervous necrosis virus infected zebrafish cells
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Citation:
Fish Shellfish Immunol. 2015 Apr;43(2):427-35. doi: 10.1016/j.fsi.2015.01.012. Epub 2015 Jan 26 Epub:
Not Epub Abstract:
The type I interferon (IFN) response has been shown to be crucial for the survival of zebrafish larvae infected with nervous... Organism or Cell Type:
cell culture: zebrafish Citation Extract: Chen HY, Liu W, Wu SY, Chiou PP, Li YH, Chen YC, Lin GH, Lu MW, Wu JL. RIG-I specifically mediates group II type I IFN activation in nervous necrosis virus infected zebrafish cells. Fish Shellfish Immunol. 2015 Apr;43(2):427-35. doi: 10.1016/j.fsi.2015.01.012. Epub 2015 Jan 26. |
TRPP2-dependent Ca2+ signaling in dorso-lateral mesoderm is required for kidney field establishment in Xenopus
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Citation:
J Cell Sci. 2015 Mar 1;128(5):888-99. doi: 10.1242/jcs.155499. Epub 2015 Jan 14 Epub:
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In Xenopus laevis embryos, kidney field specification is dependent on retinoic acid (RA) and coincides with a dramatic increase... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Futel M, Leclerc C, Le Bouffant R, Buisson I, Néant I, Umbhauer M, Moreau M, Riou JF. TRPP2-dependent Ca2+ signaling in dorso-lateral mesoderm is required for kidney field establishment in Xenopus. J Cell Sci. 2015 Mar 1;128(5):888-99. doi: 10.1242/jcs.155499. Epub 2015 Jan 14. |
Xhe2 is a member of the astacin family of metalloproteases that promotes Xenopus hatching
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Citation:
Genesis. 2014 Dec;52(12):946-51. doi: 10.1002/dvg.22841. Epub 2014 Nov 28 Epub:
Not Epub Abstract:
Transcription factors Pax3 and Zic1 are among the earliest genes activated at the neural plate border. In Xenopus, they are... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Hong CS, Saint-Jeannet JP. Xhe2 is a member of the astacin family of metalloproteases that promotes Xenopus hatching. Genesis. 2014 Dec;52(12):946-51. doi: 10.1002/dvg.22841. Epub 2014 Nov 28. |
Neutralization of mitochondrial superoxide by superoxide dismutase 2 promotes bacterial clearance and regulates phagocyte numbers in zebrafish
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Citation:
Infect Immun. 2015 Jan;83(1):430-40. doi: 10.1128/IAI.02245-14. Epub 2014 Nov 10 Epub:
Not Epub Abstract:
Mitochondria are known primarily as the location of the electron transport chain and energy production in cells. More recently... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Peterman EM, Sullivan C, Goody MF, Rodriguez-Nunez I, Yoder JA, Kim CH. Neutralization of mitochondrial superoxide by superoxide dismutase 2 promotes bacterial clearance and regulates phagocyte numbers in zebrafish. Infect Immun. 2015 Jan;83(1):430-40. doi: 10.1128/IAI.02245-14. Epub 2014 Nov 10. |
Blood Flow Limits Endothelial Cell Extrusion in the Zebrafish Dorsal Aorta
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Citation:
Cell Rep. 2020;31(2):107505. doi:j.celrep.2020.03.069 Epub:
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Blood flow modulates endothelial cell (EC) response during angiogenesis. Shear stress is known to control gene expression... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Campinho P, Lamperti P, Boselli F, Vilfan A, Vermot J. Blood Flow Limits Endothelial Cell Extrusion in the Zebrafish Dorsal Aorta. Cell Rep. 2020;31(2):107505. doi:j.celrep.2020.03.069. |
Individual long non-coding RNAs have no overt functions in zebrafish embryogenesis, viability and fertility
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Citation:
Elife. 2019 Jan 8;8. pii: e40815. doi: 10.7554/eLife.40815 Epub:
Not Epub Abstract:
Hundreds of long non-coding RNAs (lncRNAs) have been identified as potential regulators of gene expression, but their functions... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Goudarzi M, Berg K, Pieper LM, Schier AF. Individual long non-coding RNAs have no overt functions in zebrafish embryogenesis, viability and fertility. Elife. 2019 Jan 8;8. pii: e40815. doi: 10.7554/eLife.40815. |