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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Epigenetic immune-modulation by Histone Deacetylase Activity (HDAC) of tissue and organ regeneration in Xenopus laevis

Authors:
Pentagna N, dos Santos FS, de Almeida FM, Abreu JG, Levin M, Carneiro K
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.05.936294
Epub:
Not Epub
Abstract:
In the present work we propose to shed light on the epigenetic control of immune mechanisms involved during Xenopus tail...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Pentagna N, dos Santos FS, de Almeida FM, Abreu JG, Levin M, Carneiro K. Epigenetic immune-modulation by Histone Deacetylase Activity (HDAC) of tissue and organ regeneration in Xenopus laevis. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.05.936294 .

Observation of Water Permeability in Xenopus Oocytes Expressing Gap Junction Proteins

Authors:
Hamdan J, DePriest A, Skerrett IM
Citation:
Biophys J. 2020;118(3)supp1:274A. doi:10.1016/j.bpj.2019.11.1574
Epub:
Not Epub
Abstract:
Gap junctions induce electrical and biochemical coupling of animal cells and play crucial roles in cell communication,...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Hamdan J, DePriest A, Skerrett IM. Observation of Water Permeability in Xenopus Oocytes Expressing Gap Junction Proteins. Biophys J. 2020;118(3)supp1:274A. doi:10.1016/j.bpj.2019.11.1574.

Functional architecture of deleterious genetic variants in the genome of a Wrangel Island mammoth

Authors:
Fry E, Kim SK, Chigurapti S, Mika KM, Ratan A, Dammermann A, Mitchell BJ, Miller W, Lynch VJ
Citation:
Genome Bio Evol. 2020;evz279 [Epub] doi:10.1093/gbe/evz279
Epub:
Not Epub
Abstract:
Woolly mammoths were among the most abundant cold adapted species during the Pleistocene. Their once large populations went...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Fry E, Kim SK, Chigurapti S, Mika KM, Ratan A, Dammermann A, Mitchell BJ, Miller W, Lynch VJ. Functional architecture of deleterious genetic variants in the genome of a Wrangel Island mammoth. Genome Bio Evol. 2020;evz279 [Epub] doi:10.1093/gbe/evz279.

The GINS complex is required for the survival of rapidly proliferating retinal and tectal progenitor cells during zebrafish development

Authors:
Varga M, Csalyi K, Bertyak I, Menyhard DK, Poole RJ, Cerveny KL, Kovesdi D, Baratki B, Rouse H, Vad Z, Hawkins TL, Stickney HL, Cavodeassi F, Schwarz Q, Young RM, Wilson SW
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.09.940767
Epub:
Not Epub
Abstract:
Efficient and accurate DNA replication is particularly critical in stem and progenitor cells for successful proliferation and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Varga M, Csalyi K, Bertyak I, Menyhard DK, Poole RJ, Cerveny KL, Kovesdi D, Baratki B, Rouse H, Vad Z, Hawkins TL, Stickney HL, Cavodeassi F, Schwarz Q, Young RM, Wilson SW. The GINS complex is required for the survival of rapidly proliferating retinal and tectal progenitor cells during zebrafish development. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.09.940767.

miR-128a Acts as a Regulator in Cardiac Development by Modulating Differentiation of Cardiac Progenitor Cell Populations

Authors:
Hoelscher CS, Stich T, Diehm A, Lahm H, Dreßen M, Zhang Z, Neb I, Aherrahrou Z, Erdmann J, Schunkert H, Santamaria G, Cuda G, Gilsbach R, Hein L, Lange R, Hassel D, Krane M, Doppler AS
Citation:
Int J Molec Sci. 2020;21(3);1158. doi:10.3390/ijms21031158
Epub:
Not Epub
Abstract:
MicroRNAs (miRs) appear to be major, yet poorly understood players in regulatory networks guiding cardiogenesis. We sought to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hoelscher CS, Stich T, Diehm A, Lahm H, Dreßen M, Zhang Z, Neb I, Aherrahrou Z, Erdmann J, Schunkert H, Santamaria G, Cuda G, Gilsbach R, Hein L, Lange R, Hassel D, Krane M, Doppler AS. miR-128a Acts as a Regulator in Cardiac Development by Modulating Differentiation of Cardiac Progenitor Cell Populations. Int J Molec Sci. 2020;21(3);1158. doi:10.3390/ijms21031158.

YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow

Authors:
Lundin V, Sugden WW, Theodore LN, Sousa PM, Han A, Chou S, Wrighton PJ, Cox AG, Ingber DE, Goessling W, Daley GQ, North TE
Citation:
Dev Cell. 2020;[Epub ahead of print] doi:10.1016/j.devcel.2020.01.006
Epub:
Yes
Abstract:
Hematopoietic stem and progenitor cells (HSPCs), first specified from hemogenic endothelium (HE) in the ventral dorsal aorta (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lundin V, Sugden WW, Theodore LN, Sousa PM, Han A, Chou S, Wrighton PJ, Cox AG, Ingber DE, Goessling W, Daley GQ, North TE. YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow. Dev Cell. 2020;[Epub ahead of print] doi:10.1016/j.devcel.2020.01.006.

Mechanism for neurotransmitter-receptor matching

Authors:
Hammond-Weinberger DR, Wang Y, Glavis-Bloom A, Spitzer NC
Citation:
Proc Nat Acad Sci USA. 2020;[Epub ahead of print] doi:10.1073/pnas.1916600117
Epub:
Yes
Abstract:
Synaptic communication requires the expression of functional postsynaptic receptors that match the presynaptically released...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture, Xenopus
Citation Extract:
Hammond-Weinberger DR, Wang Y, Glavis-Bloom A, Spitzer NC. Mechanism for neurotransmitter-receptor matching. Proc Nat Acad Sci USA. 2020;[Epub ahead of print] doi:10.1073/pnas.1916600117.

Cryptic exon activation causes dystrophinopathy in two Chinese families

Authors:
Jin M, Li J-J, Xu G-R, Wang N, Wang Z-Q
Citation:
Eur J Hum Genet. 2020;[epub ahead of print] doi:10.1038/s41431-020-0578-z
Epub:
Yes
Abstract:
The X-linked recessive degenerative disease dystrophinopathy results from variants in the DMD gene. Given the large size and...
Citation Extract:
Jin M, Li J-J, Xu G-R, Wang N, Wang Z-Q. Cryptic exon activation causes dystrophinopathy in two Chinese families. Eur J Hum Genet. 2020;[epub ahead of print] doi:10.1038/s41431-020-0578-z.

Myostatin inhibition in combination with antisense oligonucleotide therapy improves outcomes in spinal muscular atrophy

Authors:
Zhou H, Meng J, Malerba A, Catapano F, Sintusek P, Jarmin S, Feng L, Lu-Nguyen N, Sun L, Mariot V, Dumonceaux J, Morgan JE, Gissen P, Dickson G, Muntoni F
Citation:
J Cachexia Sarcopenia Muscle. 2020 Feb 7. doi: 10.1002/jcsm.12542. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Spinal muscular atrophy (SMA) is caused by genetic defects in the survival motor neuron 1 (SMN1) gene that lead to...
Delivery Method:
s.c. injection
Organism or Cell Type:
mice
Citation Extract:
Zhou H, Meng J, Malerba A, Catapano F, Sintusek P, Jarmin S, Feng L, Lu-Nguyen N, Sun L, Mariot V, Dumonceaux J, Morgan JE, Gissen P, Dickson G, Muntoni F. Myostatin inhibition in combination with antisense oligonucleotide therapy improves outcomes in spinal muscular atrophy. J Cachexia Sarcopenia Muscle. 2020 Feb 7. doi: 10.1002/jcsm.12542. [Epub ahead of print].

Assessing intracellular pH regulation in H+-ATPase-rich ionocytes in zebrafish larvae using in vivo ratiometric imaging

Authors:
Yew HM, Zimmer AM, Perry SF
Citation:
J Exper Biol. 2020;[Epub ahead of print] doi:10.1242/jeb.212928
Epub:
Yes
Abstract:
The H+-ATPase rich (HR) cells of zebrafish larvae are a sub-type of ion-transporting cell located on the yolk sac epithelium...
Organism or Cell Type:
zebrafish
Citation Extract:
Yew HM, Zimmer AM, Perry SF. Assessing intracellular pH regulation in H+-ATPase-rich ionocytes in zebrafish larvae using in vivo ratiometric imaging. J Exper Biol. 2020;[Epub ahead of print] doi:10.1242/jeb.212928.

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