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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Novel eye genes systematically discovered through an integrated analysis of mouse transcriptomes and phenome
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Citation:
Comput Struct Biotechnol J. 2019 Dec 27;18:73-82. doi: 10.1016/j.csbj.2019.12.009. eCollection 2020 Epub:
Not Epub Abstract:
In the last few decades, reverse genetic and high throughput approaches have been frequently applied to the mouse (Mus musculus... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chiang CY, Ching YH, Chang TY, Hu LS, Yong YS, Keak PY, Mustika I, Lin MD, Liao BY. Novel eye genes systematically discovered through an integrated analysis of mouse transcriptomes and phenome. Comput Struct Biotechnol J. 2019 Dec 27;18:73-82. doi: 10.1016/j.csbj.2019.12.009. eCollection 2020. |
Germ plasm localisation dynamics mark distinct phases of transcriptional and post-transcriptional regulation control in primordial germ cells
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Citation:
https://www.biorxiv.org/content/10.1101/2020.01.12.903336v1 Epub:
Not Epub Abstract:
In many animal models, primordial germ cell (PGC) development depends on maternally-deposited germ plasm to avoid somatic cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: D'Orazio FM, Balwierz P, Guo Y, Rodriguez B, Jasiulewicz A, Vaquerizas JM, Cairns B, Lenhard B, Mueller F. Germ plasm localisation dynamics mark distinct phases of transcriptional and post-transcriptional regulation control in primordial germ cells. https://www.biorxiv.org/content/10.1101/2020.01.12.903336v1. |
Functional characterization of human myosin‐binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon‐specific cardiac phenotypes in zebrafish model
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Citation:
J Cellular Phys. 2020;[Epub ahead of print] doi:10.1002/jcp.29441 Epub:
Yes Abstract:
Myosin‐binding protein C 3 (MYBPC3) variants are the most common cause of hypertrophic cardiomyopathy (HCM). HCM is a complex... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Da'as SI, Yalcin HC, Nasrallah GK, Mohamed IA, Nomikos M, Yacoub M, Fakhro KA. Functional characterization of human myosin‐binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon‐specific cardiac phenotypes in zebrafish model. J Cellular Phys. 2020;[Epub ahead of print] doi:10.1002/jcp.29441. |
The Gβ1 and Gβ3 Subunits Differentially Regulate Rat Vascular Kv7 Channels
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Citation:
Front Physiol. 2020;10:1573. doi:10.3389/fphys.2019.01573 Epub:
Not Epub Abstract:
Within the vasculature Kv7 channels are key regulators of basal tone and contribute to a variety of receptor mediated... Delivery Method:
Lipofectamine 2000 Organism or Cell Type:
cell culture: rat primary renal arteries Citation Extract: Greenwood IA, Stott JB. The Gβ1 and Gβ3 Subunits Differentially Regulate Rat Vascular Kv7 Channels. Front Physiol. 2020;10:1573. doi:10.3389/fphys.2019.01573. |
Deletion of MOrpholino Binding Sites (DeMOBS) to Assess Specificity of Morphant Phenotypes
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.01.12.903211 Epub:
Not Epub Abstract:
Two complimentary approaches are widely used to study gene function in zebrafish: induction of genetic mutations, usually using... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cunningham CM, Bellipanni G, Habas R, Balciunas D. Deletion of MOrpholino Binding Sites (DeMOBS) to Assess Specificity of Morphant Phenotypes. bioRxiv. 2020;[preprint] doi:10.1101/2020.01.12.903211 . |
Slc7a14 Is Indispensable in Zebrafish Retinas
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Citation:
Front Cell Dev Biol. 2019 Dec 12;7:333. doi: 10.3389/fcell.2019.00333. eCollection 2019 Epub:
Not Epub Abstract:
Previous study has identified SLC7A14 as a new causative gene of retinitis pigmentosa (RP). However, the role of SLC7A14 has... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhuang YY, Xiang L, Wen XR, Shen RJ, Zhao N, Zheng SS, Han RY, Qu J, Lu F, Jin ZB. Slc7a14 Is Indispensable in Zebrafish Retinas. Front Cell Dev Biol. 2019 Dec 12;7:333. doi: 10.3389/fcell.2019.00333. eCollection 2019. |
Akt/Foxo pathway activation switches apoptosis to senescence in short telomere zebrafish
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Citation:
bioRxiv. 2020;[preprint] doi:/10.1101/2020.01.10.901603 Epub:
Not Epub Abstract:
Progressive telomere shortening during lifespan is associated with increased genome instability, block to cell proliferation... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: El-Maï M, Marzullo M, de Castro IP, Ferreira MG. Akt/Foxo pathway activation switches apoptosis to senescence in short telomere zebrafish. bioRxiv. 2020;[preprint] doi:/10.1101/2020.01.10.901603. |
Ascidian caveolin induces membrane curvature and protects tissue integrity and morphology during embryogenesis
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Citation:
FASEB J. 2020 Jan;34(1):1345-1361. doi: 10.1096/fj.201901281R. Epub 2019 Nov 30 Epub:
Not Epub Abstract:
Cell morphology and tissue integrity are essential for embryogenesis. Caveolins are membrane proteins that induce the formation... Delivery Method:
microinjection Organism or Cell Type:
Ciona sp. Citation Extract: Bhattachan P, Rae J, Yu H, Jung W, Wei J, Parton RG, Dong B. Ascidian caveolin induces membrane curvature and protects tissue integrity and morphology during embryogenesis. FASEB J. 2020 Jan;34(1):1345-1361. doi: 10.1096/fj.201901281R. Epub 2019 Nov 30. |
METTL3-mediated m6A is required for murine oocyte maturation and maternal-to-zygotic transition
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Citation:
Cell Cycle. 2020 Jan 9:1-14. doi: 10.1080/15384101.2019.1711324. [Epub ahead of print] Epub:
Not Epub Abstract:
N6-methyladenosine (m6A) is the most prevalent epigenetic modification of messenger RNA (mRNA) in higher eukaryotes; this... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Sui X, Hu Y, Ren C, Cao Q, Zhou S, Cao Y, Li M, Shu W, Huo R. METTL3-mediated m6A is required for murine oocyte maturation and maternal-to-zygotic transition. Cell Cycle. 2020 Jan 9:1-14. doi: 10.1080/15384101.2019.1711324. [Epub ahead of print]. |
ESCRT subunit CHMP4B localizes to primary cilia and is required for the structural integrity of the ciliary membrane
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Citation:
FASEB J. 2020 Jan;34(1):1331-1344. doi: 10.1096/fj.201901778R. Epub 2019 Nov 29 Epub:
Not Epub Abstract:
Proteins specialized in the detection, generation, or stabilization of membrane curvature play important roles in establishing... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jung E, Choi TI, Lee JE, Kim CH, Kim J. ESCRT subunit CHMP4B localizes to primary cilia and is required for the structural integrity of the ciliary membrane. FASEB J. 2020 Jan;34(1):1331-1344. doi: 10.1096/fj.201901778R. Epub 2019 Nov 29. |