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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity

Authors:
Levraud JP, Jouneau L, Briolat V, Laghi V, Boudinot P
Citation:
J Immunol. 2019 Nov 15. pii: ji1900804. doi: 10.4049/jimmunol.1900804. [Epub ahead of print]
Epub:
Yes
Abstract:
The evolution of the IFN system, the major innate antiviral mechanism of vertebrates, remains poorly understood. According to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Levraud JP, Jouneau L, Briolat V, Laghi V, Boudinot P. IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity. J Immunol. 2019 Nov 15. pii: ji1900804. doi: 10.4049/jimmunol.1900804. [Epub ahead of print].

Neutrophil phagocyte oxidase activity controls invasive fungal growth and inflammation in zebrafish

Authors:
Schoen TJ, Rosowski EE, Knox BP, Bennin D, Keller NP, Huttenlocher A
Citation:
J Cell Sci. 2019 Nov 13. pii: jcs.236539. doi: 10.1242/jcs.236539. [Epub ahead of print]
Epub:
Yes
Abstract:
Neutrophils are primary cells of the innate immune system that generate reactive oxygen species (ROS) and mediate host defense...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schoen TJ, Rosowski EE, Knox BP, Bennin D, Keller NP, Huttenlocher A. Neutrophil phagocyte oxidase activity controls invasive fungal growth and inflammation in zebrafish. J Cell Sci. 2019 Nov 13. pii: jcs.236539. doi: 10.1242/jcs.236539. [Epub ahead of print].

Zebrafish Vestigial Like Family Member 4b Is Required for Valvulogenesis Through Sequestration of Transcription Factor Myocyte Enhancer Factor 2c

Authors:
Xue C, Liu X, Wen B, Yang R, Gao S, Tao J, Zhou J
Citation:
Front Cell Dev Biol. 2019;7:277 doi:10.3389/fcell.2019.00277
Epub:
Not Epub
Abstract:
A variety of cardiac transcription factors/cofactors, signaling pathways, and downstream structural genes integrate to form the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xue C, Liu X, Wen B, Yang R, Gao S, Tao J, Zhou J. Zebrafish Vestigial Like Family Member 4b Is Required for Valvulogenesis Through Sequestration of Transcription Factor Myocyte Enhancer Factor 2c. Front Cell Dev Biol. 2019;7:277 doi:10.3389/fcell.2019.00277.

Morphogenetic control of zebrafish cardiac looping by Bmp signaling

Authors:
Lombardo VA, Heise M, Moghtadaei M, Bornhorst D, Männer J, Abdelilah-Seyfried S
Citation:
Development. 2019 Nov 14;146(22). pii: dev180091. doi: 10.1242/dev.180091
Epub:
Not Epub
Abstract:
Cardiac looping is an essential and highly conserved morphogenetic process that places the different regions of the developing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lombardo VA, Heise M, Moghtadaei M, Bornhorst D, Männer J, Abdelilah-Seyfried S. Morphogenetic control of zebrafish cardiac looping by Bmp signaling. Development. 2019 Nov 14;146(22). pii: dev180091. doi: 10.1242/dev.180091.

Ciglitazone - a human PPARγ agonist - disrupts dorsoventral patterning in zebrafish

Authors:
Cheng V, Dasgupta S, Reddam A, Volz DC
Citation:
PeerJ. 2019;7:e8054 doi:10.7717/peerj.8054
Epub:
Not Epub
Abstract:
Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor that regulates lipid/glucose...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cheng V, Dasgupta S, Reddam A, Volz DC. Ciglitazone - a human PPARγ agonist - disrupts dorsoventral patterning in zebrafish. PeerJ. 2019;7:e8054 doi:10.7717/peerj.8054.

Genome-wide suppressor screen identifies USP35/USP38 as therapeutic candidates for ciliopathies

Authors:
Tsai IC, Adams KA, Tzeng JA, Shennib O, Tan PL, Katsanis N
Citation:
JCI Insight. 2019 Nov 14;4(22). pii: 130516. doi: 10.1172/jci.insight.130516
Epub:
Not Epub
Abstract:
The ciliopathies are a group of phenotypically overlapping disorders caused by structural or functional defects in the primary...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tsai IC, Adams KA, Tzeng JA, Shennib O, Tan PL, Katsanis N. Genome-wide suppressor screen identifies USP35/USP38 as therapeutic candidates for ciliopathies. JCI Insight. 2019 Nov 14;4(22). pii: 130516. doi: 10.1172/jci.insight.130516.

Chemokine receptor trafficking coordinates neutrophil clustering and dispersal at wounds in zebrafish

Authors:
Coombs C, Georgantzoglou A, Walker HA, Patt J, Merten N, Poplimont H, Busch-Nentwich EM, Williams S, Kotsi C, Kostenis E, Sarris M
Citation:
Nat Commun. 2019 Nov 14;10(1):5166. doi: 10.1038/s41467-019-13107-3
Epub:
Not Epub
Abstract:
Immune cells congregate at specific loci to fight infections during inflammatory responses, a process that must be transient...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Coombs C, Georgantzoglou A, Walker HA, Patt J, Merten N, Poplimont H, Busch-Nentwich EM, Williams S, Kotsi C, Kostenis E, Sarris M. Chemokine receptor trafficking coordinates neutrophil clustering and dispersal at wounds in zebrafish. Nat Commun. 2019 Nov 14;10(1):5166. doi: 10.1038/s41467-019-13107-3.

Tfam knockdown results in reduction of mtDNA copy number, OXPHOS deficiency and abnormalities in zebrafish embryos

Authors:
Otten ABC, Kamps R, Lindsey P, Gerards M, Pendeville-Samain H, Muller M, van Tienen FHJ, Smeets HJM
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/843318
Epub:
Not Epub
Abstract:
High mitochondrial DNA (mtDNA) copy numbers are essential for oogenesis and embryogenesis and correlate with fertility of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Otten ABC, Kamps R, Lindsey P, Gerards M, Pendeville-Samain H, Muller M, van Tienen FHJ, Smeets HJM. Tfam knockdown results in reduction of mtDNA copy number, OXPHOS deficiency and abnormalities in zebrafish embryos. bioRxiv. 2019;[preprint] doi:10.1101/843318 .

von Willebrand Factor D and EGF Domains is an evolutionarily conserved and required feature of blastemas capable of multi-tissue appendage regeneration

Authors:
Leigh ND, Sessa S, Dragalzew AC, Payzin-Dogru D, Sousa JF, Aggouras AN, Johnson K, Dunlap GS, Haas BJ, Levin M, Schneider I, Whited JL
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/842948
Epub:
Not Epub
Abstract:
Regenerative ability varies tremendously across species. A common feature of regeneration of appendages such as limbs, fins,...
Delivery Method:
injection then electroporation
Organism or Cell Type:
Ambystoma mexicanum (Axolotl)
Citation Extract:
Leigh ND, Sessa S, Dragalzew AC, Payzin-Dogru D, Sousa JF, Aggouras AN, Johnson K, Dunlap GS, Haas BJ, Levin M, Schneider I, Whited JL. von Willebrand Factor D and EGF Domains is an evolutionarily conserved and required feature of blastemas capable of multi-tissue appendage regeneration. bioRxiv. 2019;[preprint] doi:10.1101/842948.

Role of the visual experience-dependent nascent proteome in neuronal plasticity

Authors:
Liu HH, McClatchy DB, Schiapparelli L, Shen W, Yates JR 3rd, Cline HT
Citation:
Elife. 2018 Feb 7;7. pii: e33420. doi: 10.7554/eLife.33420
Epub:
Not Epub
Abstract:
Experience-dependent synaptic plasticity refines brain circuits during development. To identify novel protein synthesis-...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Liu HH, McClatchy DB, Schiapparelli L, Shen W, Yates JR 3rd, Cline HT. Role of the visual experience-dependent nascent proteome in neuronal plasticity. Elife. 2018 Feb 7;7. pii: e33420. doi: 10.7554/eLife.33420.

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