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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12152 scientific papers returned from the database with the search filters currently being used below.

Environmental relevant concentrations of benzophenone-3 induced developmental neurotoxicity in zebrafish

Authors:
Tao J, Bai C, Chen Y, Zhou H, Liu Y, Shi Q, Pan W, Dong H, Li L, Xu H, Tanguay R, Huang C, Dong Q
Citation:
Sci Total Envir. 2020;721:137686. doi:10.1016/j.scitotenv.2020.137686
Epub:
Not Epub
Abstract:
Benzophenone-3 (BP3 or oxybenzone) is an organic UV filter that has been widely used in personal care products. Its frequent...
Organism or Cell Type:
zebrafish
Citation Extract:
Tao J, Bai C, Chen Y, Zhou H, Liu Y, Shi Q, Pan W, Dong H, Li L, Xu H, Tanguay R, Huang C, Dong Q. Environmental relevant concentrations of benzophenone-3 induced developmental neurotoxicity in zebrafish. Sci Total Envir. 2020;721:137686. doi:10.1016/j.scitotenv.2020.137686.

The dynein adaptor Hook2 plays essential roles in mitotic progression and cytokinesis

Authors:
Dwivedi D, Kumari A, Rathi S, Mylavarapu SVS, Sharma M
Citation:
J Cell Biol. 2019 Mar 4;218(3):871-894. doi: 10.1083/jcb.201804183. Epub 2019 Jan 23. Erratum in: J Cell Biol. 2019 Oct 7;218(10):3526-3527
Epub:
Not Epub
Abstract:
Hook proteins are evolutionarily conserved dynein adaptors that promote assembly of highly processive dynein-dynactin motor...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dwivedi D, Kumari A, Rathi S, Mylavarapu SVS, Sharma M. The dynein adaptor Hook2 plays essential roles in mitotic progression and cytokinesis. J Cell Biol. 2019 Mar 4;218(3):871-894. doi: 10.1083/jcb.201804183. Epub 2019 Jan 23. Erratum in: J Cell Biol. 2019 Oct 7;218(10):3526-3527.

Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling

Authors:
Stratman AN, Farrelly OM, Mikelis CM, Miller MF, Wang Z,Pham VN, Davis AE, Burns MC, Pezoa SA, Castranova D, Yano JJ, Kilts TM, Davis GE, Gutkind JS, Weinstein BM
Citation:
Nat Comm. 2020;11(1):1204 doi:10.1038/s41467-020-14956-z
Epub:
Not Epub
Abstract:
Anti-angiogenic therapies have generated significant interest for their potential to combat tumor growth. However, tumor...
Delivery Method:
microinjection, Vivo-Morpholino
Organism or Cell Type:
zebrafish, mice
Citation Extract:
Stratman AN, Farrelly OM, Mikelis CM, Miller MF, Wang Z,Pham VN, Davis AE, Burns MC, Pezoa SA, Castranova D, Yano JJ, Kilts TM, Davis GE, Gutkind JS, Weinstein BM. Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling. Nat Comm. 2020;11(1):1204 doi:10.1038/s41467-020-14956-z.

Biallelic variants in PSMB1 encoding the proteasome subunit β6 cause impairment of proteasome function, microcephaly, intellectual disability, developmental delay and short stature

Authors:
Ansar M, Ebstein F, Özkoç H, Paracha SA, Iwaszkiewicz J, Gesemann M, Zoete V, Ranza E, Santoni FA, Sarwar MT, Ahmed J, Krüger E, Bachmann-Gagescu R, Antonarakis SE
Citation:
Hum Molec Genet. 2020;[Epub] doi:10.1093/hmg/ddaa032
Epub:
Yes
Abstract:
The molecular cause of the majority of rare autosomal recessive disorders remains unknown. Consanguinity due to extensive...
Organism or Cell Type:
zebrafish
Citation Extract:
Ansar M, Ebstein F, Özkoç H, Paracha SA, Iwaszkiewicz J, Gesemann M, Zoete V, Ranza E, Santoni FA, Sarwar MT, Ahmed J, Krüger E, Bachmann-Gagescu R, Antonarakis SE. Biallelic variants in PSMB1 encoding the proteasome subunit β6 cause impairment of proteasome function, microcephaly, intellectual disability, developmental delay and short stature. Hum Molec Genet. 2020;[Epub] doi:10.1093/hmg/ddaa032.

Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis

Authors:
Fujii K, Nakajo K, Egashira Y, Yamamoto Y, Kitada K, Taniguchi K, Kawai M, Tomiyama H, Kawakami K, Uchiyama K, Ono F
Citation:
Cell Rep. 2020;30(9):2879-88. doi:10.1016/j.celrep.2020.02.024
Epub:
Not Epub
Abstract:
Peristalsis is indispensable for physiological function of the gut. The enteric nervous system (ENS) plays an important role in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fujii K, Nakajo K, Egashira Y, Yamamoto Y, Kitada K, Taniguchi K, Kawai M, Tomiyama H, Kawakami K, Uchiyama K, Ono F. Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis. Cell Rep. 2020;30(9):2879-88. doi:10.1016/j.celrep.2020.02.024.

Amelioration of Large Bile Duct Damage by Histamine-2 Receptor Vivo-Morpholino Treatment

Authors:
Kennedy L, Meadows V, Kyritsi K, Pham L, Kundu D, Kulkarni R, Cerritos K, Demieville J, Hargrove L, Glaser S, Zhou T, Jaeger V, Alpini G, Francis H
Citation:
Am J Pathol. 2020;190( 5):1018–29 doi:10.1016/j.ajpath.2020.01.013
Epub:
Not Epub
Abstract:
Histamine binds to one of the four G-protein–coupled receptors expressed by large cholangiocytes. Histamine specifically...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Kennedy L, Meadows V, Kyritsi K, Pham L, Kundu D, Kulkarni R, Cerritos K, Demieville J, Hargrove L, Glaser S, Zhou T, Jaeger V, Alpini G, Francis H. Amelioration of Large Bile Duct Damage by Histamine-2 Receptor Vivo-Morpholino Treatment. Am J Pathol. 2020;190( 5):1018–29 doi:10.1016/j.ajpath.2020.01.013.

Cell-type specific global reprogramming of the transcriptome and epigenome in induced neurons with the 16p11.2 neuropsychiatric CNVs

Authors:
Ward TR, Qu PP, Leung LC, Zhou B, Muench KL, Khechaduri A, Plastini MJ, Charlton CA, Pattni R, Ho S, Ho M, Huang Y, Zhou P, Hallmayer JF, Mourrain P, Palmer TD, Zhang X, Urban AE
Citation:
Eur J Hum Genet. 2025 Dec;33(12):1698-1707. doi: 10.1038/s41431-025-01856-3. Epub 2025 May 15. PMID: 40374944; PMCID: PMC12341848
Epub:
Not Epub
Abstract:
Copy number variants (CNVs), either deletions or duplications, at the 16p11.2 locus in the human genome are known to increase...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ward TR, Qu PP, Leung LC, Zhou B, Muench KL, Khechaduri A, Plastini MJ, Charlton CA, Pattni R, Ho S, Ho M, Huang Y, Zhou P, Hallmayer JF, Mourrain P, Palmer TD, Zhang X, Urban AE. Cell-type specific global reprogramming of the transcriptome and epigenome in induced neurons with the 16p11.2 neuropsychiatric CNVs. Eur J Hum Genet. 2025 Dec;33(12):1698-1707. doi: 10.1038/s41431-025-01856-3. Epub 2025 May 15. PMID: 40374944; PMCID: PMC12341848.

Single-cell reconstruction with spatial context of migrating neural crest cells and their microenvironments during vertebrate head and neck formation

Authors:
Morrison JA, McLennan R, Teddy JM, Scott AR, Kasemeier-Kulesa JC, Gogol MM, Kulesa PM
Citation:
Development. 2021 Nov 15;148(22):dev199468. doi: 10.1242/dev.199468. Epub 2021 Nov 17. PMID: 35020873
Epub:
Not Epub
Abstract:
The dynamics of multipotent neural crest cell differentiation and invasion as cells travel throughout the vertebrate embryo...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Morrison JA, McLennan R, Teddy JM, Scott AR, Kasemeier-Kulesa JC, Gogol MM, Kulesa PM. Single-cell reconstruction with spatial context of migrating neural crest cells and their microenvironments during vertebrate head and neck formation. Development. 2021 Nov 15;148(22):dev199468. doi: 10.1242/dev.199468. Epub 2021 Nov 17. PMID: 35020873.

Zebrafish miR-462-731 is required for digestive organs development

Authors:
Huang Y, Huang C-X, Wang W-F, Liu H, Wang H-L
Citation:
Comp Biochem Physiol Part D Genomics Proteomics. 2020 Feb 29;34:100679. doi: 10.1016/j.cbd.2020.100679. [Epub ahead of print]
Epub:
Not Epub
Abstract:
With-no-lysine (K)-1 (WNK1) is the founding member of family of four protein kinases with atypical placement of catalytic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huang Y, Huang C-X, Wang W-F, Liu H, Wang H-L. Zebrafish miR-462-731 is required for digestive organs development. Comp Biochem Physiol Part D Genomics Proteomics. 2020 Feb 29;34:100679. doi: 10.1016/j.cbd.2020.100679. [Epub ahead of print].

WNK1 Kinase Stimulates Angiogenesis to Promote Tumor Growth and Metastasis

Authors:
Sie Z-L, Li R-Y, Sampurna PB, Hsu P-J, Liu S-C, Wang H-D, Huang C-L, Yuh C-H
Citation:
Cancers. 2020;12(3):[Epub] doi:0.3390/cancers12030575
Epub:
Not Epub
Abstract:
With-no-lysine (K)-1 (WNK1) is the founding member of family of four protein kinases with atypical placement of catalytic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sie Z-L, Li R-Y, Sampurna PB, Hsu P-J, Liu S-C, Wang H-D, Huang C-L, Yuh C-H. WNK1 Kinase Stimulates Angiogenesis to Promote Tumor Growth and Metastasis. Cancers. 2020;12(3):[Epub] doi:0.3390/cancers12030575.

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