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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Zebrafish Pax1a and Pax1b are required for pharyngeal pouch morphogenesis and ceratobranchial cartilage development
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Citation:
Mech Dev. 2020 Feb 13:103598. doi: 10.1016/j.mod.2020.103598. [Epub ahead of print] Epub:
Yes Abstract:
Pharyngeal arches are derived from all three germ layers and molecular interactions among the tissue types are required for... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu YH, Lin TC, Hwang SL. Zebrafish Pax1a and Pax1b are required for pharyngeal pouch morphogenesis and ceratobranchial cartilage development. Mech Dev. 2020 Feb 13:103598. doi: 10.1016/j.mod.2020.103598. [Epub ahead of print]. |
Triazine-cored polymeric vectors for antisense oligonucleotide delivery in vitro and in vivo
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Citation:
J Nanobiotechnology. 2020 Feb 18;18(1):34. doi: 10.1186/s12951-020-0586-8 Epub:
Not Epub Abstract:
BACKGROUND: The polymer-based drug/gene delivery is promising for the treatment of inherent or acquire disease, because of the... Delivery Method:
triazine-cored amphiphilic polymers (TAPs) Organism or Cell Type:
cell culture: C2C12E50 myoblast & C2C12E23 differentiated cells, mice mdx Citation Extract: Wang M, Wu B, Tucker JD, Shah SN, Lu P, Lu Q. Triazine-cored polymeric vectors for antisense oligonucleotide delivery in vitro and in vivo. J Nanobiotechnology. 2020 Feb 18;18(1):34. doi: 10.1186/s12951-020-0586-8. |
Estrogen acts via estrogen receptor 2b to regulate hepatobiliary fate during vertebrate development
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Citation:
Hepatology. 2020 Nov;72(5):1786-1799. doi: 10.1002/hep.31184 Epub:
Yes Abstract:
During liver development bipotent progenitor cells differentiate into hepatocytes and biliary epithelial cells (BECs) to ensure... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chaturantabut S, Shwartz A, Garnaas MK, LaBella K, Li CC, Carroll KJ, Cutting CC, Budrow N, Palaria A, Gorelick DA, Tremblay KD, North TE, Goessling W. Estrogen acts via estrogen receptor 2b to regulate hepatobiliary fate during vertebrate development. Hepatology. 2020 Nov;72(5):1786-1799. doi: 10.1002/hep.31184. |
NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and Xenopus laevis models
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Citation:
PLoS Genet. 2020;16(2):e1008590. doi:10.1371/journal.pgen.1008590 Epub:
Not Epub Abstract:
The 1.6 Mbp deletion on chromosome 3q29 is associated with a range of neurodevelopmental disorders, including schizophrenia,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Singh MD, Jensen M, Lasser M, Huber E, Yusuff T, Pizzo L, Lifschutz B, Desai I, Kubina A, Yennawar S, Kim S, Iyer J, Rincon-Limas DE, Lowery LA, Girirajan S. NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and Xenopus laevis models. PLoS Genet. 2020;16(2):e1008590. doi:10.1371/journal.pgen.1008590. |
CRISPR-Cas13d induces efficient mRNA knock-down in animal embryos
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.01.13.904763 Epub:
Not Epub Abstract:
Early embryonic development is driven exclusively by maternal gene products deposited into the oocyte. Although critical in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kushawah G, del Prado JA-N, Martinez-Morales JR, DeVore M, Guelfo JR, Brannan EO, Wang W, Corbin TJ, Moran AM, Alvarado AS, Málaga-Trillo E, Takacs CM, Bazzini AA, Moreno-Mateos MA. CRISPR-Cas13d induces efficient mRNA knock-down in animal embryos. bioRxiv. 2020;[preprint] doi:10.1101/2020.01.13.904763. |
Cancer-associated HIF-2α impacts trunk neural crest stemness
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.01.22.915199 Epub:
Not Epub Abstract:
The neural crest is a stem cell population that gives rise to sympathetic ganglia, the cell type of origin of neuroblastoma.... Delivery Method:
injection then electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Mohlin S, Persson CU, Fredlund E, Monni E, Lindvall JM, Kokaia Z, Hammarlund E, Bronner ME. Cancer-associated HIF-2α impacts trunk neural crest stemness. bioRxiv. 2020;[preprint] doi:10.1101/2020.01.22.915199. |
AMPK complex activation promotes sarcolemmal repair in dysferlinopathy
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Citation:
Molec Ther. 2020;[Epub ahead of print] doi:10.1016/j.ymthe.2020.02.006 Epub:
Yes Abstract:
Mutations in dysferlin are responsible for a group of progressive, recessively inherited muscular dystrophies known as... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ono H, Suzuki N, Shin-Kanno S-i, Kawahara G, Izumi R, Takahashi T, Kitajima Y, Osana S, Nakamura N, Akiyama T, Ikeda K, Shijo T, Mitsuzawa S, Nagatomi R, Araki N, Yasui A, Warita H, Hayashi YK, Miyake K,i Aoki M. AMPK complex activation promotes sarcolemmal repair in dysferlinopathy. Molec Ther. 2020;[Epub ahead of print] doi:10.1016/j.ymthe.2020.02.006. |
Cadherin clustering controls heterogeneous, asymmetric junction dynamics during vertebrate axis elongation
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.11.944033 Epub:
Not Epub Abstract:
Tissue morphogenesis requires the control of physical forces by molecular patterning systems encoded in the genome. For example... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Huebner R, Malmi-Kakkada AN, Sarikaya S, Weng S, Thirumalai D, Wallingford JB. Cadherin clustering controls heterogeneous, asymmetric junction dynamics during vertebrate axis elongation. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.11.944033 . |
Deletion of a conserved Gata2 enhancer impairs haemogenic endothelium programming and adult Zebrafish haematopoiesis
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Citation:
Comm Biol. 2020;3(1):71 doi:10.1038/s42003-020-0798-3 Epub:
Not Epub Abstract:
Gata2 is a key transcription factor required to generate Haematopoietic Stem and Progenitor Cells (HSPCs) from haemogenic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dobrzycki T, Mahony CB, Krecsmarik M, Koyunlar C, Rispoli R, Peulen-Zink J, Gussinklo K, Fedlaoui B, de Pater E, Patient R, Monteiro R. Deletion of a conserved Gata2 enhancer impairs haemogenic endothelium programming and adult Zebrafish haematopoiesis. Comm Biol. 2020;3(1):71 doi:10.1038/s42003-020-0798-3. |
Carboxyl ester lipase is highly conserved in utilizing maternal supplied lipids during early development of zebrafish and human
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Citation:
Biochim Biophys Acta: Molec Cell Bio Lipid. 2020;[Epub ahead of print] doi:10.1016/j.bbalip.2020.158663 Epub:
Yes Abstract:
Carboxyl ester lipase (Cel), is a lipolytic enzyme secreted by the pancreas, which hydrolyzes various species of lipids in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Qiu Y, Sun S, Yua X, Zhou J, Cai W, Qian L. Carboxyl ester lipase is highly conserved in utilizing maternal supplied lipids during early development of zebrafish and human. Biochim Biophys Acta: Molec Cell Bio Lipid. 2020;[Epub ahead of print] doi:10.1016/j.bbalip.2020.158663. |