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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
Leishmania donovani Subverts Host Immune Response by Epigenetic Reprogramming of Macrophage M(Lipopolysaccharides + IFN-γ)/M(IL-10) Polarization
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Citation:
J Immunol. 2020;204 (10) 2762-2778. doi: 10.4049/jimmunol.1900251. [Epub ahead of print] Epub:
Not Epub Abstract:
Reciprocal changes in histone lysine methylation/demethylation of M(LPS + IFN-γ)/M(IL-10) genes is one of the factors that... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Parmar N, Chandrakar P, Kar S. Leishmania donovani Subverts Host Immune Response by Epigenetic Reprogramming of Macrophage M(Lipopolysaccharides + IFN-γ)/M(IL-10) Polarization. J Immunol. 2020;204 (10) 2762-2778. doi: 10.4049/jimmunol.1900251. [Epub ahead of print]. |
Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling
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Citation:
PLoS Biol. 2020;18(4):e3000696. doi:10.1371/journal.pbio.3000696 Epub:
Not Epub Abstract:
It is well known that various developmental signals play diverse roles in hematopoietic stem and progenitor cell (HSPC)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Heng J, Lv P, Zhang Y, Cheng X, Wang L, Ma D, Liu F. Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling. PLoS Biol. 2020;18(4):e3000696. doi:10.1371/journal.pbio.3000696. |
Pathological mechanism and antisense oligonucleotide-mediated rescue of a non-coding variant suppressing factor 9 RNA biogenesis leading to hemophilia B
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Citation:
PLoS Genet. 2020;16(4):e1008690. doi:10.1371/journal.pgen.1008690 Epub:
Not Epub Abstract:
Loss-of-function mutations in the human coagulation factor 9 (F9) gene lead to hemophilia B. Here, we dissected the... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HeLa Citation Extract: Krooss S, Werwitzke S, Kopp J, Rovai A, Varnholt D, Wachs AS, Goyenvalle A, Aarstma-Rus A, Ott M, Tiede A, Langemeier J, Bohne J. Pathological mechanism and antisense oligonucleotide-mediated rescue of a non-coding variant suppressing factor 9 RNA biogenesis leading to hemophilia B. PLoS Genet. 2020;16(4):e1008690. doi:10.1371/journal.pgen.1008690. |
The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I
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Citation:
Sci Adv. 2020;6(15):eaax3969. doi:10.1126/sciadv.aax3969 Epub:
Not Epub Abstract:
During mitotic prophase, cohesins are removed from chromosome arms by Wapl to ensure faithful sister chromatid separation.... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Zhou C, Miao Y, Cui Z, ShiYang X, Zhang Y, Xiong B. The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I. Sci Adv. 2020;6(15):eaax3969. doi:10.1126/sciadv.aax3969. |
Piezo1 and outflow tract and aortic valve development
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Citation:
J Molec Cell Cardiol. 2020;[Epub] doi:10.1016/j.yjmcc.2020.03.013 Epub:
Yes Abstract:
Aims: During embryogenesis, the onset of circulatory blood flow generates a variety of hemodynamic forces which reciprocally... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Faucherre A, ou Maati HM, Nasr N, Pinard A, Theron A, Odelin G, Desvignes JP, Salgado D, Collod-Béroud G, Avierinos JF, Lebon G, Zaffran S, Jopling C. Piezo1 and outflow tract and aortic valve development. J Molec Cell Cardiol. 2020;[Epub] doi:10.1016/j.yjmcc.2020.03.013. |
Trade-off between somatic and germline repair in a vertebrate supports the expensive germ line hypothesis
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Citation:
Proc Natl Acad Sci U S A. 2020 Apr 3. pii: 201918205. doi: 10.1073/pnas.1918205117. [Epub ahead of print] Epub:
Yes Abstract:
The disposable soma theory is a central tenet of the biology of aging where germline immortality comes at the cost of an aging... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen HY, Jolly C, Bublys K, Marcu D, Immler S. Trade-off between somatic and germline repair in a vertebrate supports the expensive germ line hypothesis. Proc Natl Acad Sci U S A. 2020 Apr 3. pii: 201918205. doi: 10.1073/pnas.1918205117. [Epub ahead of print]. |
Zebrafish mutants in vegfab can affect endothelial cell proliferation without altering ERK phosphorylation and are phenocopied by loss of PI3K signaling
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Citation:
Dev Biol. 2022 Jun;486:26-43. doi: 10.1016/j.ydbio.2022.03.006. Epub 2022 Mar 23. PMID: 35337795; PMCID: PMC11238767 Epub:
Not Epub Abstract:
The formation of appropriately patterned blood vessel networks requires endothelial cell migration and proliferation. Signaling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lange M, Ohnesorge N, Hoffmann D, Rocha SF, Benedito R, Siekmann AF. Zebrafish mutants in vegfab can affect endothelial cell proliferation without altering ERK phosphorylation and are phenocopied by loss of PI3K signaling. Dev Biol. 2022 Jun;486:26-43. doi: 10.1016/j.ydbio.2022.03.006. Epub 2022 Mar 23. PMID: 35337795; PMCID: PMC11238767. |
Chondroitin sulfate proteoglycan 4 regulates zebrafish body axis organization via Wnt/planar cell polarity pathway
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Citation:
PLoS ONE. 2020;15(4):e0230943. doi:10.1371/journal.pone.0230943 Epub:
Not Epub Abstract:
Pericellular and extracellular proteoglycans play an important role in modulating morphogen gradients and signal transductions... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lee Y-H, Kawakami K, HuangFu W-C, Liu I-H. Chondroitin sulfate proteoglycan 4 regulates zebrafish body axis organization via Wnt/planar cell polarity pathway. PLoS ONE. 2020;15(4):e0230943. doi:10.1371/journal.pone.0230943. |
Igf2bp1 is required for hepatic outgrowth during early liver development in zebrafish
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Citation:
Gene. 2020 Mar 30:144632. doi: 10.1016/j.gene.2020.144632. [Epub ahead of print] Epub:
Yes Abstract:
IGF2BPs, a subclass of RNA-binding proteins, regulate cellular differentiation, proliferation and migration during multiple... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wu J, Lu C, Ge S, Mei J, Li X, Guo W. Igf2bp1 is required for hepatic outgrowth during early liver development in zebrafish. Gene. 2020 Mar 30:144632. doi: 10.1016/j.gene.2020.144632. [Epub ahead of print]. |
NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis
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Citation:
Cell Rep. 2020;40(13):4473-89. doi:10.1016/j.celrep.2020.03.031 Epub:
Not Epub Abstract:
Terminal selectors are transcription factors that control the morphological, physiological, and molecular features that... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Tournière O, Dolan D, Richards GS, Sunagar K, Columbus-Shenkar YY, Moran Y, Rentzsch F. NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis. Cell Rep. 2020;40(13):4473-89. doi:10.1016/j.celrep.2020.03.031. |