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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21
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Citation:
Cell Rep. 2020;30(1):124-36.e4. doi:10.1016/j.celrep.2019.12.015 Epub:
Not Epub Abstract:
Increased glycolytic metabolism recently emerged as an essential process driving host defense against Mycobacterium... Delivery Method:
Lipofectamine 2000 Organism or Cell Type:
cell culture: bone-marrow-derived macrophages (BMDMs) Citation Extract: Hackett EE, Charles-Messance H, O’Leary SM, Gleeson LE, Muñoz-Wolf N, Case S, Wedderburn A, Johnston DGW, Williams MA, Smyth A, Ouimet M, Moore KJ, Lavelle EC, Corr SC, Gordon SV, Keane J, Sheedy FJ. Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21. Cell Rep. 2020;30(1):124-36.e4. doi:10.1016/j.celrep.2019.12.015. |
U1 snRNP regulates cancer cell migration and invasion in vitro
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Citation:
Nat Commun. 2020;11:1. doi:10.1038/s41467-019-13993-7 Epub:
Not Epub Abstract:
Stimulated cells and cancer cells have widespread shortening of mRNA 3’-untranslated regions (3’UTRs) and switches to shorter... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HeLa, A549, MCF-7 & MDA-MB-231 Citation Extract: Oh J, Venters CC, Di C, Pinto AM, Wan L, Younis I, Cai Z, Arai C, So BR, Duan J, Dreyfuss G. U1 snRNP regulates cancer cell migration and invasion in vitro. Nat Commun. 2020;11:1. doi:10.1038/s41467-019-13993-7. |
Glycogen storage in a zebrafish Pompe disease model is reduced by 3-BrPA treatment
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Citation:
Biochim Biophys Acta Mol Basis Dis. 2020;[epub ahead of print] doi:10.1016/j.bbadis.2020.165662 Epub:
Yes Abstract:
Pompe disease (PD) is an autosomal recessive muscular disorder caused by deficiency of the glycogen hydrolytic enzyme acid α-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bragato C, Carra S, Blasevich F, Salerno F, Brix A, Bassi A, Beltrame M, Cotelli F, Maggi L, Mantegazza R, Mora M. Glycogen storage in a zebrafish Pompe disease model is reduced by 3-BrPA treatment. Biochim Biophys Acta Mol Basis Dis. 2020;[epub ahead of print] doi:10.1016/j.bbadis.2020.165662. |
Disrupted ER membrane protein complex-mediated topogenesis drives congenital neural crest defects
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Citation:
J Clin Invest. 2020 Jan 6. pii: 129308. doi: 10.1172/JCI129308. [Epub ahead of print] Epub:
Yes Abstract:
Multipass membrane proteins have a myriad of functions, including transduction of cell-cell signals, ion transport, and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Marquez J, Criscione J, Charney RM, Prasad MS, Hwang WY, Mis EK, García-Castro MI, Khokha MK. Disrupted ER membrane protein complex-mediated topogenesis drives congenital neural crest defects. J Clin Invest. 2020 Jan 6. pii: 129308. doi: 10.1172/JCI129308. [Epub ahead of print]. |
march5 Governs the Convergence and Extension Movement for Organization of the Telencephalon and Diencephalon in Zebrafish Embryos
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Citation:
Mol Cells. 2020 Jan 7. doi: 10.14348/molcells.2019.0210. [Epub ahead of print] Epub:
Yes Abstract:
MARCH5 is a RING finger E3 ligase involved in mitochondrial integrity, cellular protein homeostasis, and the regulation of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jung J, Choi I, Ro H, Huh TL, Choe J, Rhee M. march5 Governs the Convergence and Extension Movement for Organization of the Telencephalon and Diencephalon in Zebrafish Embryos. Mol Cells. 2020 Jan 7. doi: 10.14348/molcells.2019.0210. [Epub ahead of print]. |
Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer’s model of adult zebrafish brain
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Citation:
PLoS Biol.2020:18(1):e3000585. doi:10.1371/journal.pbio.3000585 Epub:
Not Epub Abstract:
It was recently suggested that supplying the brain with new neurons could counteract Alzheimer’s disease (AD). This provocative... Delivery Method:
i.c.v. microinjection Organism or Cell Type:
zebrafish Citation Extract: Bhattarai P, Cosacak MI, Mashkaryan V, Demir S, Popova SD, Govindarajan N, Brandt K, Zhang Y, Chang W, Ampatzis K, Kizil C. Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer’s model of adult zebrafish brain. PLoS Biol.2020:18(1):e3000585. doi:10.1371/journal.pbio.3000585. |
Vezf1 regulates cardiac structure and contractile function
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Citation:
EBioMed. 2020;51:102608. doi:10.1016/j.ebiom.2019.102608 Epub:
Not Epub Abstract:
Background: Vascular endothelial zinc finger 1 (Vezf1) is a transcription factor previously shown to regulate vasculogenesis... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Paavola J, Alakoski T, Ulvila J, Kilpiö T, Sirén J, Perttunen S, Narumanchi S, Wang H, Lin R, Porvari K, Junttila J, Huikuri H, Immonen K, Lakkisto P, Magga J, Tikkanen I, Kerkelä R. Vezf1 regulates cardiac structure and contractile function. EBioMed. 2020;51:102608. doi:10.1016/j.ebiom.2019.102608. |
CEP41-mediated ciliary tubulin glutamylation drives angiogenesis through AURKA-dependent deciliation
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Citation:
EMBO Rep. 2019 Dec 29:e48290. doi: 10.15252/embr.201948290. [Epub ahead of print] Epub:
Yes Abstract:
The endothelial cilium is a microtubule-based organelle responsible for blood flow-induced mechanosensation and signal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ki SM, Kim JH, Won SY, Oh SJ, Lee IY, Bae YK, Chung KW, Choi BO, Park B, Choi EJ, Lee JE. CEP41-mediated ciliary tubulin glutamylation drives angiogenesis through AURKA-dependent deciliation. EMBO Rep. 2019 Dec 29:e48290. doi: 10.15252/embr.201948290. [Epub ahead of print]. |
Citrullination regulates wound responses and tissue regeneration in zebrafish
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Citation:
bioRxiv. 2019:[preprint] doi:10.1101/2019.12.27.889378 Epub:
Not Epub Abstract:
Calcium signaling is an important early step in wound healing, yet how these early signals promote regeneration remains unclear... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Golenberg N, Squirrell JM, Bennin DA, Rindy J, Pistono PE, Eliceiri KW, Shelef MA, Kang J, Huttenlocher A. Citrullination regulates wound responses and tissue regeneration in zebrafish. bioRxiv. 2019:[preprint] doi:10.1101/2019.12.27.889378. |
Spatio-temporal expression and distribution of collagen VI during zebrafish development
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Citation:
Sci Rep. 2019 Dec 27;9(1):19851. doi: 10.1038/s41598-019-56445-4 Epub:
Not Epub Abstract:
Collagen VI (ColVI) is an extracellular matrix (ECM) protein involved in a range of physiological and pathological conditions.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tonelotto V, Trapani V, Bretaud S, Heumüller SE, Wagener R, Ruggiero F, Bonaldo P. Spatio-temporal expression and distribution of collagen VI during zebrafish development. Sci Rep. 2019 Dec 27;9(1):19851. doi: 10.1038/s41598-019-56445-4. |