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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
A Reversible RNA On-Switch That Controls Expression of Aav-Delivered Transgenes In Vivo
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Citation:
Molec Ther. 2020;28(4S1):224. abstract 510. doi:10.1016/j.ymthe.2020.04.019 Epub:
Not Epub Abstract:
Widespread use of gene therapy technologies is limited in part by the lack of small genetic switches with wide dynamic ranges... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Zhong G, Wang H, Farzan M. A Reversible RNA On-Switch That Controls Expression of Aav-Delivered Transgenes In Vivo. Molec Ther. 2020;28(4S1):224. abstract 510. doi:10.1016/j.ymthe.2020.04.019. |
Development of a Minimized Exons 45-55 Skipping Cocktail for the Treatment of Duchenne Muscular Dystrophy
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Citation:
Molec Ther. 2020;28(4S1):113 abstract 237. doi:10.1016/j.ymthe.2020.04.019 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a fatal X-linked recessive neuromuscular disorder characterized by... Delivery Method:
peptide-linked Organism or Cell Type:
mice Citation Extract: Lim KRQ, Huang Y, Maruyama R, Woo S, Dzierlega K, Moulton H, Yokota T. Development of a Minimized Exons 45-55 Skipping Cocktail for the Treatment of Duchenne Muscular Dystrophy. Molec Ther. 2020;28(4S1):113 abstract 237. doi:10.1016/j.ymthe.2020.04.019. |
Restoration of Full-Length Dystrophin Expression in the Dup2 Mouse Induced by Systemic Delivery of a Peptide-Conjugated Morpholino Oligomer
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Citation:
Molec Ther. 2020;28(4S1):20 abstract 39. doi:10.1016/j.ymthe.2020.04.019 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is an x-linked recessive genetic disorder caused by mutations that disrupt the... Delivery Method:
peptide-linked Organism or Cell Type:
mice Citation Extract: Gushchina LV, Grounds KM, Huang N, Frair E, Schnell FJ, Hanson GJ, Simmons T, Wein N, Flanigan KM. Restoration of Full-Length Dystrophin Expression in the Dup2 Mouse Induced by Systemic Delivery of a Peptide-Conjugated Morpholino Oligomer. Molec Ther. 2020;28(4S1):20 abstract 39. doi:10.1016/j.ymthe.2020.04.019. |
Pharyngeal pouches provide a niche microenvironment for arch artery progenitor specification
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.07.083493 Epub:
Not Epub Abstract:
The paired pharyngeal arch arteries (PAAs) are transient blood vessels connecting the heart with the dorsal aorta during... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mao A, Li L, Liu J, Mingming Z, Ning G, Cao Y, Wang Q. Pharyngeal pouches provide a niche microenvironment for arch artery progenitor specification. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.07.083493. |
Furry is required for cell movements during gastrulation and functionally interacts with NDR1
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.08.083980 Epub:
Not Epub Abstract:
Gastrulation is a key event in animal embryogenesis during which the germ layers precursors are rearranged and the embryonic... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Cervino AS, Moretti B, Stuckenholz C, Grecco HE, Davidson LA, Cirio MC. Furry is required for cell movements during gastrulation and functionally interacts with NDR1. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.08.083980. |
Aryl hydrocarbon receptor mediates larval zebrafish fin duplication following exposure to benzofluoranthenes
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Citation:
Toxicol Sci. 2020 May 8. pii: kfaa063. doi: 10.1093/toxsci/kfaa063. [Epub ahead of print] Epub:
Yes Abstract:
The aryl hydrocarbon receptor (AHR) mediates developmental toxicity of several xenobiotic classes including polycyclic aromatic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Garland MA, Geier MC, Bugel SM, Shankar P, Dunham CL, Brown JM, Tilton SC, Tanguay RL. Aryl hydrocarbon receptor mediates larval zebrafish fin duplication following exposure to benzofluoranthenes. Toxicol Sci. 2020 May 8. pii: kfaa063. doi: 10.1093/toxsci/kfaa063. [Epub ahead of print]. |
Uncoupling Splicing From Transcription Using Antisense Oligonucleotides Reveals a Dual Role for I Exon Donor Splice Sites in Antibody Class Switching
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Citation:
Front Immunol. 2020;11:780. doi:10.3389/fimmu.2020.00780 Epub:
Not Epub Abstract:
Class switch recombination (CSR) changes antibody isotype by replacing Cμ constant exons with different constant exons located... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: murine splenic B cells Citation Extract: Marchalot A, Ashi MO, Lambert JM, Carrion C, Lecardeur S, Srour N, Delpy L, Le Pennec S. Uncoupling Splicing From Transcription Using Antisense Oligonucleotides Reveals a Dual Role for I Exon Donor Splice Sites in Antibody Class Switching. Front Immunol. 2020;11:780. doi:10.3389/fimmu.2020.00780. |
Composition-dependent thermodynamics of intracellular phase separation
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Citation:
Nature. 2020;[Epub]. doi:10.1038/s41586-020-2256-2 Epub:
Yes Abstract:
Intracellular bodies such as nucleoli, Cajal bodies and various signalling assemblies represent membraneless organelles, or... Citation Extract: Riback JA, Zhu L, Ferrolino MC, Tolbert M, Mitrea DM, Sanders DW, Wei M-T, Kriwacki RW, Brangwynne CP. Composition-dependent thermodynamics of intracellular phase separation. Nature. 2020;[Epub]. doi:10.1038/s41586-020-2256-2. |
Knocking-down of the Prokineticin receptor 2 affects reveals its complex role in the regulation of the hypothalamus-pituitary-gonadal axis in the zebrafish model
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Citation:
Sci Rep. 2020;10(1):7632 doi:10.1038/s41598-020-64077-2 Epub:
Not Epub Abstract:
Prokineticin receptors (PROKR1 and PROKR2) are G protein-coupled receptors which control human central and peripheral... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bassi I, Luzzani F, Marelli F, Vezzoli V, Cotellessa L, Prober DA, Persani L, Gothilf Y, Bonomi M. Knocking-down of the Prokineticin receptor 2 affects reveals its complex role in the regulation of the hypothalamus-pituitary-gonadal axis in the zebrafish model. Sci Rep. 2020;10(1):7632 doi:10.1038/s41598-020-64077-2. |
Activating transcription factor 3 coordinates differentiation of cardiac and hematopoietic progenitors by regulating glucose metabolism
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Citation:
Sci Adv. 2020;6(19):eaay9466 doi:10.1126/sciadv.aay9466 Epub:
Not Epub Abstract:
The cardiac and hematopoietic progenitors (CPs and HPs, respectively) in the mesoderm ultimately form a well-organized... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yin H-M, Yan L-F, Liu Q, Peng Z, Zhang C-Y, Xia Y, Su D, Gu A-H, Zhou Y. Activating transcription factor 3 coordinates differentiation of cardiac and hematopoietic progenitors by regulating glucose metabolism. Sci Adv. 2020;6(19):eaay9466 doi:10.1126/sciadv.aay9466. |