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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing
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Citation:
J Am Chem Soc. 2020;[Epub ahead of print] doi:10.1021/jacs.0c00768 Epub:
Yes Abstract:
Approximately 95% of human genes are alternatively spliced, and aberrant splicing events can cause disease. One pre-mRNA that... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: HeLa Citation Extract: Chen JL, Zhang P, Abe M, Aikawa H, Zhang L, Frank AJ, Zembryski T, Hubbs C, Park HJ, Withka J, Steppan C, Rogers L, Cabral S, Pettersson M, Wager TT, Fountain MA, Rumbaugh G, Childs-Disney JL, Disney MD. Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. J Am Chem Soc. 2020;[Epub ahead of print] doi:10.1021/jacs.0c00768. |
Peptide Conjugated Morpholinos for Management of The Huanglongbing Pathosystem
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Citation:
Pest Manag Sci. 2020 May 1. doi: 10.1002/ps.5877. [Epub ahead of print] Epub:
Yes Abstract:
BACKGROUND: 'Candidatus Liberibacter asiaticus' (CLas) is the causal agent of the devastating citrus disease... Delivery Method:
peptide-linked Organism or Cell Type:
Candidatus Liberibacter asiaticus, Wolbachia Citation Extract: Sandoval-Mojica AF, Altman S, Hunter WB, Pelz-Stelinski KS. Peptide Conjugated Morpholinos for Management of The Huanglongbing Pathosystem. Pest Manag Sci. 2020 May 1. doi: 10.1002/ps.5877. [Epub ahead of print]. |
The vertebrate-specific VENTX/NANOG gene empowers neural crest with ectomesenchyme potential
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Citation:
Sci Adv. 2020;6(18):eaaz1469. doi:10.1126/sciadv.aaz1469 Epub:
Not Epub Abstract:
During Cambrian, unipotent progenitors located at the neural (plate) border (NB) of an Olfactoria chordate embryo acquired the... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Scerbo P, Monsoro-Burq AH. The vertebrate-specific VENTX/NANOG gene empowers neural crest with ectomesenchyme potential. Sci Adv. 2020;6(18):eaaz1469. doi:10.1126/sciadv.aaz1469 . |
miR-103/107 regulates left-right asymmetry in zebrafish by modulating Kupffer's vesicle development and ciliogenesis
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Citation:
Biochem Biophys Res Commun. 2020 Apr 22. pii: S0006-291X(20)30792-0. doi: 10.1016/j.bbrc.2020.04.066. [Epub ahead of print] Epub:
Yes Abstract:
In zebrafish, cilia movement within the Kupffer's vesicle (KV) generates a fluid flow responsible for accumulating nodal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Heigwer J, Kutzner J, Haeussler M, Burkhalter MD, Draebing T, Juergensen L, Katus HA, Philipp M, Westhoff JH, Hassel D. miR-103/107 regulates left-right asymmetry in zebrafish by modulating Kupffer's vesicle development and ciliogenesis. Biochem Biophys Res Commun. 2020 Apr 22. pii: S0006-291X(20)30792-0. doi: 10.1016/j.bbrc.2020.04.066. [Epub ahead of print]. |
Fgf-driven Tbx protein activities directly induce myf5 and myod to initiate zebrafish myogenesis
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Citation:
Development. 2020;147(8):[Epub] doi:10.1242/dev.184689 Epub:
Not Epub Abstract:
Skeletal muscle derives from dorsal mesoderm formed during vertebrate gastrulation. Fibroblast growth factor (Fgf) signalling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Osborn DPS, Li K, Cutty SJ, Nelson AC, Wardle FC, Hinits Y, Hughes SM. Fgf-driven Tbx protein activities directly induce myf5 and myod to initiate zebrafish myogenesis. Development. 2020;147(8):[Epub] doi:10.1242/dev.184689. |
Practical Synthesis of Quinoline-Protected Morpholino Oligomers for Light-Triggered Regulation of Gene Function
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Citation:
Molecules. 2020;25(9):2078. doi:10.3390/molecules25092078 Epub:
Not Epub Abstract:
Photoactivatable cyclic caged morpholino oligomers (ccMOs) represent a promising tool to selectively regulate gene expression... Citation Extract: Deodato D, Dore TM. Practical Synthesis of Quinoline-Protected Morpholino Oligomers for Light-Triggered Regulation of Gene Function. Molecules. 2020;25(9):2078. doi:10.3390/molecules25092078. |
A homozygous MRPL24 mutation causes a complex movement disorder and affects the mitoribosome assembly
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Citation:
Neurobiol Dis. 2020 Apr 25:104880. doi: 10.1016/j.nbd.2020.104880. [Epub ahead of print] Epub:
Yes Abstract:
Mitochondrial ribosomal protein large 24 (MRPL24) is 1 of the 82 protein components of mitochondrial ribosomes, playing an... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nottia MD, Marchese M, Verrigni D, Mutti C, Torraco A, Oliva R, Fernandez-Vizarra E, Morani F, Trani G, Rizza T, Ghezzi D, Ardissone A, Nesti C, Vasco G, Zeviani M, Minczuk M, Bertini E, Santorelli FM, Carrozzo R. A homozygous MRPL24 mutation causes a complex movement disorder and affects the mitoribosome assembly. Neurobiol Dis. 2020 Apr 25:104880. doi: 10.1016/j.nbd.2020.104880. [Epub ahead of print]. |
Mis12 controls cyclin B1 stabilization via Cdc14B-mediated APC/CCdh1 regulation during meiotic G2/M transition in mouse oocytes
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Citation:
Development. 2020;147(8):[Epub ahead of print] doi:10.1242/dev.185322 Epub:
Yes Abstract:
Mammalian oocytes are arrested at G2/prophase of the first meiosis. After a hormone surge, oocytes resume meiosis, undergoing... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Bai G-Y, Choe MH, Kim J-S, Oh JS. Mis12 controls cyclin B1 stabilization via Cdc14B-mediated APC/CCdh1 regulation during meiotic G2/M transition in mouse oocytes. Development. 2020;147(8):[Epub ahead of print] doi:10.1242/dev.185322. |
Role of kif2c, A Gene Related to ALL Relapse, in Embryonic Hematopoiesis in Zebrafish
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Citation:
Int J Molec Sci. 2020;21(9):3127. doi:10.3390/ijms21093127 Epub:
Not Epub Abstract:
Relapse of acute lymphoblastic leukemia (ALL) is dangerous and it worsens the prognosis of patients; however, prognostic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Oh C-K, Kang JW, Lee Y, Myung K, Ha M, Kang J, Kwon EJ, Kim Y, Oh S-O, Heo HJ, Kim S, Kim YH. Role of kif2c, A Gene Related to ALL Relapse, in Embryonic Hematopoiesis in Zebrafish. Int J Molec Sci. 2020;21(9):3127. doi:10.3390/ijms21093127. |
Nodal and Planar Cell Polarity signaling cooperate to regulate zebrafish convergence and extension gastrulation movements
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Citation:
Elife. 2020 Apr 22;9. pii: e54445. doi: 10.7554/eLife.54445. [Epub ahead of print] Epub:
Not Epub Abstract:
During vertebrate gastrulation, convergence & extension (C&E) of the primary anteroposterior (AP) embryonic axis is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Williams MLK, Solnica-Krezel L. Nodal and Planar Cell Polarity signaling cooperate to regulate zebrafish convergence and extension gastrulation movements. Elife. 2020 Apr 22;9. pii: e54445. doi: 10.7554/eLife.54445. [Epub ahead of print]. |