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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Coordinated assembly and release of adhesions builds apical junctional belts during de novo polarisation of an epithelial tube

Authors:
Symonds A, Buckley C, Williams C, Clarke J
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.16.950543
Epub:
Not Epub
Abstract:
We uncover the mechanisms allowing the generation of two opposing apical epithelial surfaces within the centre of an initially...
Link:
https://www.biorxiv.org/content/10.1101/2020.02.16.950543v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Symonds A, Buckley C, Williams C, Clarke J. Coordinated assembly and release of adhesions builds apical junctional belts during de novo polarisation of an epithelial tube. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.16.950543.

Neutrophils use selective autophagy receptor p62/SQSTM1 to target Staphylococcus aureus for degradation in vivo in zebrafish

Authors:
Gibson JF, Prajsnar TK, Hill CJ, Tooke AK, Serba JJ, Tonge RD, Foster SJ, Grierson AJ, Ingham PW, Renshaw SA, Johnston SA
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/604884
Epub:
Not Epub
Abstract:
Autophagy leads to degradation of cellular components and has an important role in restricting intracellular pathogens....
Link:
https://www.biorxiv.org/content/10.1101/604884v2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gibson JF, Prajsnar TK, Hill CJ, Tooke AK, Serba JJ, Tonge RD, Foster SJ, Grierson AJ, Ingham PW, Renshaw SA, Johnston SA. Neutrophils use selective autophagy receptor p62/SQSTM1 to target Staphylococcus aureus for degradation in vivo in zebrafish. bioRxiv. 2020;[preprint] doi:10.1101/604884.

Pou5f3 and Sox19b select gene expression repertoire at Zygotic Genome Activation

Authors:
Gao M, Veil M, Rosenblatt M, Gebhard A, Hass H, Buryanova L, Yampolsky LY, Grüning B, Timmer J, Onichtchouk D
Citation:
bioRxiv. 2020:[preprint] doi:10.1101/2020.02.16.949362
Epub:
Not Epub
Abstract:
PouV and SoxB1 family transcription factors (TFs) have emerged as master regulators of cell fate transitions. To investigate...
Link:
https://www.biorxiv.org/content/10.1101/2020.02.16.949362v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gao M, Veil M, Rosenblatt M, Gebhard A, Hass H, Buryanova L, Yampolsky LY, Grüning B, Timmer J, Onichtchouk D. Pou5f3 and Sox19b select gene expression repertoire at Zygotic Genome Activation. bioRxiv. 2020:[preprint] doi:10.1101/2020.02.16.949362 .

Targeting the unfolded protein response components differentially sensitizes breast tumors to doxorubicin while modulating chemotherapy-induced cardiotoxicities [abstract]

Authors:
Soto-Pantoja D, Clear K, Cook KL
Citation:
Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P5-14-19. doi:10.1158/1538-7445.SABCS19-P5-14-19
Epub:
Not Epub
Abstract:
Background: The unfolded protein response (UPR) is an endoplasmic reticulum pathway stimulated when the protein folding demand...
Link:
https://cancerres.aacrjournals.org/content/80/4_Supplement/P5-14-19
Organism or Cell Type:
mouse xenograft 4T1-luciferase triple negative breast cancer cells
Citation Extract:
Soto-Pantoja D, Clear K, Cook KL. Targeting the unfolded protein response components differentially sensitizes breast tumors to doxorubicin while modulating chemotherapy-induced cardiotoxicities [abstract]. Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P5-14-19. doi:10.1158/1538-7445.SABCS19-P5-14-19.

Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site

Authors:
Smith SJ, Towers N, Demetriou K, Mohun TJ
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.13.947424
Epub:
Not Epub
Abstract:
ADP-ribosylhydrolase-like 1 (Adprhl1) is a pseudoenzyme expressed in the developing heart myocardium of all vertebrates. In the...
Link:
https://www.biorxiv.org/content/10.1101/2020.02.13.947424v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Smith SJ, Towers N, Demetriou K, Mohun TJ. Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.13.947424.

Diastereoselective Synthesis of Phosphorodiamidate Morpholino Dimers

Authors:
Min SJ, Kim NY, Chae HY, Chun KH
Citation:
Bull Korean Chem Soc. 2020. doi:10.1002/bkcs.11958
Epub:
Not Epub
Abstract:
No abstract available.
Link:
https://onlinelibrary.wiley.com/doi/full/10.1002/bkcs.11958
Citation Extract:
Min SJ, Kim NY, Chae HY, Chun KH. Diastereoselective Synthesis of Phosphorodiamidate Morpholino Dimers. Bull Korean Chem Soc. 2020. doi:10.1002/bkcs.11958.

Photoreceptor progenitor dynamics in the zebrafish embryo retina and its modulation by primary cilia and N-cadherin

Authors:
Aparicio G, Rodao M, Badano JL, Zolessi FR
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.13.947663
Epub:
Not Epub
Abstract:
Background: Photoreceptors of the vertebrate neural retina are originated from the neuroepithelium, and like other neurons,...
Link:
https://www.biorxiv.org/content/10.1101/2020.02.13.947663v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Aparicio G, Rodao M, Badano JL, Zolessi FR. Photoreceptor progenitor dynamics in the zebrafish embryo retina and its modulation by primary cilia and N-cadherin. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.13.947663 .

Zebrafish Pax1a and Pax1b are required for pharyngeal pouch morphogenesis and ceratobranchial cartilage development

Authors:
Liu YH, Lin TC, Hwang SL
Citation:
Mech Dev. 2020 Feb 13:103598. doi: 10.1016/j.mod.2020.103598. [Epub ahead of print]
Epub:
Yes
Abstract:
Pharyngeal arches are derived from all three germ layers and molecular interactions among the tissue types are required for...
Link:
https://www.sciencedirect.com/science/article/pii/S0925477320300034
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu YH, Lin TC, Hwang SL. Zebrafish Pax1a and Pax1b are required for pharyngeal pouch morphogenesis and ceratobranchial cartilage development. Mech Dev. 2020 Feb 13:103598. doi: 10.1016/j.mod.2020.103598. [Epub ahead of print].

Triazine-cored polymeric vectors for antisense oligonucleotide delivery in vitro and in vivo

Authors:
Wang M, Wu B, Tucker JD, Shah SN, Lu P, Lu Q
Citation:
J Nanobiotechnology. 2020 Feb 18;18(1):34. doi: 10.1186/s12951-020-0586-8
Epub:
Not Epub
Abstract:
BACKGROUND: The polymer-based drug/gene delivery is promising for the treatment of inherent or acquire disease, because of the...
Link:
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-020-0586-8
Delivery Method:
triazine-cored amphiphilic polymers (TAPs)
Organism or Cell Type:
cell culture: C2C12E50 myoblast & C2C12E23 differentiated cells, mice mdx
Citation Extract:
Wang M, Wu B, Tucker JD, Shah SN, Lu P, Lu Q. Triazine-cored polymeric vectors for antisense oligonucleotide delivery in vitro and in vivo. J Nanobiotechnology. 2020 Feb 18;18(1):34. doi: 10.1186/s12951-020-0586-8.

Estrogen acts via estrogen receptor 2b to regulate hepatobiliary fate during vertebrate development

Authors:
Chaturantabut S, Shwartz A, Garnaas MK, LaBella K, Li CC, Carroll KJ, Cutting CC, Budrow N, Palaria A, Gorelick DA, Tremblay KD, North TE, Goessling W
Citation:
Hepatology. 2020 Nov;72(5):1786-1799. doi: 10.1002/hep.31184
Epub:
Yes
Abstract:
During liver development bipotent progenitor cells differentiate into hepatocytes and biliary epithelial cells (BECs) to ensure...
Link:
https://aasldpubs.onlinelibrary.wiley.com/doi/abs/10.1002/hep.31184
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chaturantabut S, Shwartz A, Garnaas MK, LaBella K, Li CC, Carroll KJ, Cutting CC, Budrow N, Palaria A, Gorelick DA, Tremblay KD, North TE, Goessling W. Estrogen acts via estrogen receptor 2b to regulate hepatobiliary fate during vertebrate development. Hepatology. 2020 Nov;72(5):1786-1799. doi: 10.1002/hep.31184.

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