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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Transcriptome profiling of the branchial arches reveals cell type composition and a conserved signature of neural crest cell invasion
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.28.969915 Epub:
Not Epub Abstract:
The vertebrate branchial arches that give rise to structures of the head, neck, and heart form with very dynamic tissue growth... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Morrison JA, McLennan R, Teddy JM, Scott AR, Kasemeier-Kulesa K-K, Gogol MM, Kulesa PM. Transcriptome profiling of the branchial arches reveals cell type composition and a conserved signature of neural crest cell invasion. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.28.969915 . |
Prmt5 promotes vascular morphogenesis in zebrafish independently of its methyltransferase activity
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Citation:
BioRxiv. 2020;[preprint] doi:10.1101/2020.02.27.967810 Epub:
Not Epub Abstract:
In vertebrate, blood cell formation is tightly associated with the development of the vascular system. While the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Quillien A, Boulet M, Ethuin S, Vandel L. Prmt5 promotes vascular morphogenesis in zebrafish independently of its methyltransferase activity. BioRxiv. 2020;[preprint] doi:10.1101/2020.02.27.967810. |
Zebrafish miR-462-731 is required for digestive organs development
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Citation:
Comp Biochem Physiol Part D Genomics Proteomics. 2020 Feb 29;34:100679. doi: 10.1016/j.cbd.2020.100679. [Epub ahead of print] Epub:
Not Epub Abstract:
With-no-lysine (K)-1 (WNK1) is the founding member of family of four protein kinases with atypical placement of catalytic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Huang Y, Huang C-X, Wang W-F, Liu H, Wang H-L. Zebrafish miR-462-731 is required for digestive organs development. Comp Biochem Physiol Part D Genomics Proteomics. 2020 Feb 29;34:100679. doi: 10.1016/j.cbd.2020.100679. [Epub ahead of print]. |
WNK1 Kinase Stimulates Angiogenesis to Promote Tumor Growth and Metastasis
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Citation:
Cancers. 2020;12(3):[Epub] doi:0.3390/cancers12030575 Epub:
Not Epub Abstract:
With-no-lysine (K)-1 (WNK1) is the founding member of family of four protein kinases with atypical placement of catalytic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sie Z-L, Li R-Y, Sampurna PB, Hsu P-J, Liu S-C, Wang H-D, Huang C-L, Yuh C-H. WNK1 Kinase Stimulates Angiogenesis to Promote Tumor Growth and Metastasis. Cancers. 2020;12(3):[Epub] doi:0.3390/cancers12030575. |
Aberrant Expression of a Non-muscle RBFOX2 Isoform Triggers Cardiac Conduction Defects in Myotonic Dystrophy
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Citation:
Dev Cell. 2020;[Epub ahead of print] doi:10.1016/j.devcel.2020.01.037 Epub:
Yes Abstract:
Myotonic dystrophy type 1 (DM1) is a multisystemic genetic disorder caused by the CTG repeat expansion in the 3′-untranslated... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HL-1 Citation Extract: Misra C, Bangru S, Lin F, Lam K, Koenig SN, Lubbers ER, Hedhli J, Murphy NP, Parker DJ, Dobrucki LW, Cooper TA, Tajkhorshid E, Mohler PJ, Kalsotra A. Aberrant Expression of a Non-muscle RBFOX2 Isoform Triggers Cardiac Conduction Defects in Myotonic Dystrophy. Dev Cell. 2020;[Epub ahead of print] doi:10.1016/j.devcel.2020.01.037. |
Deciphering and modelling the TGF-β signalling interplays specifying the dorsal-ventral axis of the sea urchin embryo
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.26.966556 Epub:
Not Epub Abstract:
During sea urchin development, secretion of Nodal and BMP2/4 ligands and their antagonists Lefty and Chordin from a ventral... Delivery Method:
microinjection Organism or Cell Type:
Paracentrotus lividus (sea urchin) Citation Extract: Floc'hlay S, Jimenez MDM, Hernandez C, Haillot E, Thomas-Chollier M, Lepage T, Thieffry D. Deciphering and modelling the TGF-β signalling interplays specifying the dorsal-ventral axis of the sea urchin embryo. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.26.966556. |
Wip1 regulates Smad4 phosphorylation and inhibits TGF‐β signaling
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Citation:
EMBO Rep. 2020;[Epub] doi:10.15252/embr.201948693 Epub:
Yes Abstract:
The tumor suppressor Smad4, a key mediator of the TGF‐β/BMP pathways, is essential for development and tissue homeostasis.... Organism or Cell Type:
Xenopus Citation Extract: Park D-S, Yoon G-H, Kim E-Y, Lee T, Kim K, Lee PCW, Chang E-J, Choi S-C. Wip1 regulates Smad4 phosphorylation and inhibits TGF‐β signaling. EMBO Rep. 2020;[Epub] doi:10.15252/embr.201948693. |
Comparison of the efficacy of MOE and PMO modifications of systemic antisense oligonucleotides in a severe SMA mouse model
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Citation:
Nucl Acids Res. 2020;[Epub ahead of print] doi:10.1093/nar/gkaa126 Epub:
Yes Abstract:
Spinal muscular atrophy (SMA) is a motor neuron disease. Nusinersen, a splice-switching antisense oligonucleotide (ASO), was... Delivery Method:
subcutaneous (s.c.) injection Organism or Cell Type:
mice Citation Extract: Sheng L, Rigo F, Bennett CF, Krainer AR, Hua Y. Comparison of the efficacy of MOE and PMO modifications of systemic antisense oligonucleotides in a severe SMA mouse model. Nucl Acids Res. 2020;[Epub ahead of print] doi:10.1093/nar/gkaa126. |
pmar1/phb homeobox genes and the evolution of the double-negative gate for endomesoderm specification in echinoderms
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Citation:
Development. 2020;147:[Epub ahead of print] doi:10.1242/dev.182139 Epub:
Not Epub Abstract:
In several model animals, the earliest phases of embryogenesis are regulated by lineage-specific genes, such as Drosophila... Delivery Method:
microinjection Organism or Cell Type:
Patria pectinifera (sea star) Citation Extract: Yamazaki A, Morino Y, Urata M, Yamaguchi M, Minokawa T, Furukawa R, Kondo M, Wada H. pmar1/phb homeobox genes and the evolution of the double-negative gate for endomesoderm specification in echinoderms. Development. 2020;147:[Epub ahead of print] doi:10.1242/dev.182139. |
Active acetylcholine receptors prevent the atrophy of skeletal muscles and favor reinnervation
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Citation:
Nat Commun. 2020;11:1073 doi:s41467-019-14063-8 Epub:
Not Epub Abstract:
Denervation of skeletal muscles induces severe muscle atrophy, which is preceded by cellular alterations such as increased... Delivery Method:
lipofectamine 2000 Organism or Cell Type:
cell culture: myofibrils Citation Extract: Cisterna BA, Vargas AA, Puebla C, Fernández P, Escamilla R, Lagos CF, Matus MF, Vilos C, Cea LA, Barnafi E, Gaete H, Escobar DF, Cardozo CP, Sáez JC. Active acetylcholine receptors prevent the atrophy of skeletal muscles and favor reinnervation. Nat Commun. 2020;11:1073 doi:s41467-019-14063-8. |