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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Deficiency in the endocytic adaptor proteins PHETA1/2 impair renal and craniofacial development
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Citation:
Dis Models Mec. 2020;[Epub] doi:10.1242/dmm.041913 Epub:
Not Epub Abstract:
A critical barrier in the treatment of endosomal and lysosomal diseases is the lack of understanding of the in vivo functions... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ates KM, Wang T, Moreland T, Veeranan-Karmegam R, Ma M, Jeter C, Anand P, Wenzel W, Kim H-G, Wolfe LA, Joshi A. Stephen JA, Adams DR, Markello T, Tifft CJ, Settlage R, Gahl WA, Gonsalvez GB, Malicdan MC, Flanagan-Steet H, Pan YA. Deficiency in the endocytic adaptor proteins PHETA1/2 impair renal and craniofacial development. Dis Models Mec. 2020;[Epub] doi:10.1242/dmm.041913. |
Histone variant H3.3 residue S31 is essential for Xenopus gastrulation regardless of the deposition pathway
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Citation:
Nat Comm. 2020;11:1256. doi:10.1038/s41467-020-15084-4 Epub:
Not Epub Abstract:
Vertebrates exhibit specific requirements for replicative H3 and non-replicative H3.3 variants during development. To... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Sitbon D, Boyarchuk E, Dingli F, Loew D, Almouzni G. Histone variant H3.3 residue S31 is essential for Xenopus gastrulation regardless of the deposition pathway. Nat Comm. 2020;11:1256. doi:10.1038/s41467-020-15084-4. |
Modeling Bainbridge-Ropers Syndrome in Xenopus laevis Embryos
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Citation:
Front Physiol. 2020 Feb 18;11:75. doi: 10.3389/fphys.2020.00075. eCollection 2020 Epub:
Not Epub Abstract:
The Additional sex combs-like (ASXL1-3) genes are linked to human neurodevelopmental disorders. The de novo truncating variants... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Lichtig H, Artamonov A, Polevoy H, Reid CD, Bielas SL, Frank D. Modeling Bainbridge-Ropers Syndrome in Xenopus laevis Embryos. Front Physiol. 2020 Feb 18;11:75. doi: 10.3389/fphys.2020.00075. eCollection 2020. |
Environmental relevant concentrations of benzophenone-3 induced developmental neurotoxicity in zebrafish
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Citation:
Sci Total Envir. 2020;721:137686. doi:10.1016/j.scitotenv.2020.137686 Epub:
Not Epub Abstract:
Benzophenone-3 (BP3 or oxybenzone) is an organic UV filter that has been widely used in personal care products. Its frequent... Organism or Cell Type:
zebrafish Citation Extract: Tao J, Bai C, Chen Y, Zhou H, Liu Y, Shi Q, Pan W, Dong H, Li L, Xu H, Tanguay R, Huang C, Dong Q. Environmental relevant concentrations of benzophenone-3 induced developmental neurotoxicity in zebrafish. Sci Total Envir. 2020;721:137686. doi:10.1016/j.scitotenv.2020.137686. |
The dynein adaptor Hook2 plays essential roles in mitotic progression and cytokinesis
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Citation:
J Cell Biol. 2019 Mar 4;218(3):871-894. doi: 10.1083/jcb.201804183. Epub 2019 Jan 23. Erratum in: J Cell Biol. 2019 Oct 7;218(10):3526-3527 Epub:
Not Epub Abstract:
Hook proteins are evolutionarily conserved dynein adaptors that promote assembly of highly processive dynein-dynactin motor... Link:
Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dwivedi D, Kumari A, Rathi S, Mylavarapu SVS, Sharma M. The dynein adaptor Hook2 plays essential roles in mitotic progression and cytokinesis. J Cell Biol. 2019 Mar 4;218(3):871-894. doi: 10.1083/jcb.201804183. Epub 2019 Jan 23. Erratum in: J Cell Biol. 2019 Oct 7;218(10):3526-3527. |
Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling
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Citation:
Nat Comm. 2020;11(1):1204 doi:10.1038/s41467-020-14956-z Epub:
Not Epub Abstract:
Anti-angiogenic therapies have generated significant interest for their potential to combat tumor growth. However, tumor... Delivery Method:
microinjection, Vivo-Morpholino Organism or Cell Type:
zebrafish, mice Citation Extract: Stratman AN, Farrelly OM, Mikelis CM, Miller MF, Wang Z,Pham VN, Davis AE, Burns MC, Pezoa SA, Castranova D, Yano JJ, Kilts TM, Davis GE, Gutkind JS, Weinstein BM. Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling. Nat Comm. 2020;11(1):1204 doi:10.1038/s41467-020-14956-z. |
Biallelic variants in PSMB1 encoding the proteasome subunit β6 cause impairment of proteasome function, microcephaly, intellectual disability, developmental delay and short stature
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Citation:
Hum Molec Genet. 2020;[Epub] doi:10.1093/hmg/ddaa032 Epub:
Yes Abstract:
The molecular cause of the majority of rare autosomal recessive disorders remains unknown. Consanguinity due to extensive... Organism or Cell Type:
zebrafish Citation Extract: Ansar M, Ebstein F, Özkoç H, Paracha SA, Iwaszkiewicz J, Gesemann M, Zoete V, Ranza E, Santoni FA, Sarwar MT, Ahmed J, Krüger E, Bachmann-Gagescu R, Antonarakis SE. Biallelic variants in PSMB1 encoding the proteasome subunit β6 cause impairment of proteasome function, microcephaly, intellectual disability, developmental delay and short stature. Hum Molec Genet. 2020;[Epub] doi:10.1093/hmg/ddaa032. |
Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis
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Citation:
Cell Rep. 2020;30(9):2879-88. doi:10.1016/j.celrep.2020.02.024 Epub:
Not Epub Abstract:
Peristalsis is indispensable for physiological function of the gut. The enteric nervous system (ENS) plays an important role in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fujii K, Nakajo K, Egashira Y, Yamamoto Y, Kitada K, Taniguchi K, Kawai M, Tomiyama H, Kawakami K, Uchiyama K, Ono F. Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis. Cell Rep. 2020;30(9):2879-88. doi:10.1016/j.celrep.2020.02.024. |
Amelioration of Large Bile Duct Damage by Histamine-2 Receptor Vivo-Morpholino Treatment
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Citation:
Am J Pathol. 2020;190( 5):1018–29 doi:10.1016/j.ajpath.2020.01.013 Epub:
Not Epub Abstract:
Histamine binds to one of the four G-protein–coupled receptors expressed by large cholangiocytes. Histamine specifically... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Kennedy L, Meadows V, Kyritsi K, Pham L, Kundu D, Kulkarni R, Cerritos K, Demieville J, Hargrove L, Glaser S, Zhou T, Jaeger V, Alpini G, Francis H. Amelioration of Large Bile Duct Damage by Histamine-2 Receptor Vivo-Morpholino Treatment. Am J Pathol. 2020;190( 5):1018–29 doi:10.1016/j.ajpath.2020.01.013. |
Genome-wide molecular effects of the neuropsychiatric 16p11 CNVs in an iPSC-to-iN neuronal model
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.09.940965 Epub:
Not Epub Abstract:
Copy number variants (CNVs), either deletions or duplications, at the 16p11.2 locus in the human genome are known to increase... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ward TR, Zhang X, Louis C. Leung, Zhou B, Muench K, Roth JG, Khechaduri A, Plastini MJ, Charlton C, Pattni R, Ho S, Ho M, Huang Y, Hallmayer JF, Mourrain P, Palmer TD, Urban AE. Genome-wide molecular effects of the neuropsychiatric 16p11 CNVs in an iPSC-to-iN neuronal model. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.09.940965 . |