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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
DOCK3 is a dosage-sensitive regulator of skeletal muscle and Duchenne muscular dystrophy-associated pathologies
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.03.27.010223 Epub:
Not Epub Abstract:
DOCK3 is a member of the DOCK family of guanine nucleotide exchange factors that function to regulate cell migration, fusion,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Reid AL, Wang Y, Samani A, Hightower RM, Lopez MA, Shawn R Gilbert, Ianov L, Crossman DK, Italia LJD, Millay DP, van Groen T, Halade GV, Alexander MS. DOCK3 is a dosage-sensitive regulator of skeletal muscle and Duchenne muscular dystrophy-associated pathologies. bioRxiv. 2020;[preprint] doi:10.1101/2020.03.27.010223 . |
Triploidization Disrupts Early Reproductive Development of Females and Alters Phenotypic Sex Ratios of Sablefish Anoplopoma fimbria
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Citation:
Presentation at Aquaculture America 2020, Honolulu Hawaii Epub:
Not Epub Abstract:
Escapement is an ecological concern for marine finfishes reared in net-pen systems. To mitigate this risk, we have initiated... Delivery Method:
Vivo-Morpholino bathing Organism or Cell Type:
Anoplopoma fimbria (black cod) Citation Extract: Luckenbach JA, Hayman ES, Fairgrieve WT, Wong T-T, Zohar Y, Huynh TB. Triploidization Disrupts Early Reproductive Development of Females and Alters Phenotypic Sex Ratios of Sablefish Anoplopoma fimbria. Presentation at Aquaculture America 2020, Honolulu Hawaii. |
Live imaging defines the dynamics and molecular basis of in vivo mitophagy
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.03.26.010405 Epub:
Not Epub Abstract:
Mitophagy defects are linked to aging, sarcopenia, and neurodegenerative diseases. To target this process for clinical... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wrighton PJ, Shwartz A, Heo J-M, Quenzer ED, LaBella KA, Harper JW, Wolfram Goessling W. Live imaging defines the dynamics and molecular basis of in vivo mitophagy. bioRxiv. 2020;[preprint] doi:10.1101/2020.03.26.010405 . |
GABA-Induced GnRH Release Triggers Chordate Metamorphosis
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Citation:
Curr Biol. 2020;[Epub ahead of print] doi:10.1016/j.cub.2020.02.003 Epub:
Yes Abstract:
Metamorphosis, a widespread life history strategy in metazoans, allows dispersal and use of different ecological niches through... Delivery Method:
microinjection Organism or Cell Type:
Ciona intentinalis (ascidian) Citation Extract: Hozumi A, Matsunobu S, Mita K, Treen N, Sugihara T, Horie T, Sakuma T, Yamamoto T, Shiraishi A, Hamada M, Satoh N, Sakurai K, Satake H, Sasakura Y. GABA-Induced GnRH Release Triggers Chordate Metamorphosis. Curr Biol. 2020;[Epub ahead of print] doi:10.1016/j.cub.2020.02.003. |
Loss of ap4s1 in zebrafish leads to neurodevelopmental defects resembling spastic paraplegia 52
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Citation:
Ann Clin Transl Neurol. 2020;[Epub] doi:10.1002/acn3.51018 Epub:
Yes Abstract:
Autosomal recessive spastic paraplegia 52 is caused by biallelic mutations in AP4S1 which encodes a subunit of the adaptor... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: D’Amore A, Tessa A, Naef V, Bassi MT, Citterio A, Romaniello R, Fichi G, Galatolo D, Mero S, Battini R, Bertocci G, Baldacci J, Sicca F, Gemignani F, Ricca I, Rubegni A, Hirst J, Marchese M, Sahin M, Ebrahimi‐Fakhari D, Filippo M. Santorelli FM. Loss of ap4s1 in zebrafish leads to neurodevelopmental defects resembling spastic paraplegia 52. Ann Clin Transl Neurol. 2020;[Epub] doi:10.1002/acn3.51018. |
Function of Arl4aa in the Initiation of Hematopoiesis in Zebrafish by Maintaining Golgi Complex Integrity in Hemogenic Endothelium
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Citation:
Stem Cell Rep. 2020;[Epub ahead of print] doi:10.1016/j.stemcr.2020.02.012 Epub:
Yes Abstract:
ADP-ribosylation factor-like 4aa (Arl4aa) is a member of the ADP-ribosylation factor family. It is expressed in hematopoietic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Guo Y, Cheng BYL, Wang D, Ma ACH, He B-L, Man TK, Cheung MPL, Shi X, Ng NKL, Leung AYH. Function of Arl4aa in the Initiation of Hematopoiesis in Zebrafish by Maintaining Golgi Complex Integrity in Hemogenic Endothelium. Stem Cell Rep. 2020;[Epub ahead of print] doi:10.1016/j.stemcr.2020.02.012. |
De Novo Phosphoinositide Synthesis in Zebrafish Is Required for Triad Formation but Not Essential for Myogenesis
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.03.24.005306 Epub:
Not Epub Abstract:
Phosphoinositides (PIPs) and their regulatory enzymes are key players in many cellular processes and are required for aspects... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dowling JJ, Smith L, Fabian L, Al-Maawali A, Noche RR. De Novo Phosphoinositide Synthesis in Zebrafish Is Required for Triad Formation but Not Essential for Myogenesis. bioRxiv. 2020;[preprint] doi:10.1101/2020.03.24.005306. |
The failure of microglia to digest developmental apoptotic cells contributes to the pathology of RNASET2‐deficient leukoencephalopathy
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Citation:
Glia. 2020;[Epub ahead of print] doi:10.1002/glia.23829 Epub:
Yes Abstract:
The contribution of microglia in neurological disorders is emerging as a leading disease driver rather than a consequence of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hamilton N, Rutherford HA, Petts JJ, Isles HM, Weber T, Henneke M, Gärtner J, Dunning M, Renshaw SA. The failure of microglia to digest developmental apoptotic cells contributes to the pathology of RNASET2‐deficient leukoencephalopathy. Glia. 2020;[Epub ahead of print] doi:10.1002/glia.23829. |
BMP Signaling Gradient Scaling in the Zebrafish Pectoral Fin
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Citation:
Cell Rep. 2020;30(12):4292-302.e7 doi:10.1016/j.celrep.2020.03.024 Epub:
Not Epub Abstract:
Secreted growth factors can act as morphogens that form spatial concentration gradients in developing organs, thereby... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mateus R, Holtzer L, Seum C, Hadjivasiliou Z, Dubois M, Jülicher F, Gonzalez-Gaitan M. BMP Signaling Gradient Scaling in the Zebrafish Pectoral Fin. Cell Rep. 2020;30(12):4292-302.e7 doi:10.1016/j.celrep.2020.03.024. |
Genetic compensation in a stable slc25a46 mutant zebrafish: A case for using F0 CRISPR mutagenesis to study phenotypes caused by inherited disease
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Citation:
PLoS ONE. 2020;15(3):e0230566. doi:10.1371/journal.pone.0230566 Epub:
Not Epub Abstract:
A phenomenon of genetic compensation is commonly observed when an organism with a disease-bearing mutation shows incomplete... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Buglo E, Sarmiento E, Martuscelli NB, Sant DW, Danzi MC, Abrams AJ, Dallman JE, Züchner S. Genetic compensation in a stable slc25a46 mutant zebrafish: A case for using F0 CRISPR mutagenesis to study phenotypes caused by inherited disease. PLoS ONE. 2020;15(3):e0230566. doi:10.1371/journal.pone.0230566. |