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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
Proteomic Identification Reveals the Role of Ciliary Extracellular‐Like Vesicle in Cardiovascular Function
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Citation:
Adv Sci. 2020;[Early epub] doi:10.1002/advs.201903140 Epub:
Yes Abstract:
Primary cilia are shown to have membrane swelling, also known as ciliary bulbs. However, the role of these structures and their... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mohieldin AM, Pala R, Sherpa RT, Alanazi M, Alanazi A, Shamloo K, Ahsan A, AbouAlaiwi WA, Moresco JJ. Yates JR III, Nauli SM. Proteomic Identification Reveals the Role of Ciliary Extracellular‐Like Vesicle in Cardiovascular Function. Adv Sci. 2020;[Early epub] doi:10.1002/advs.201903140. |
TPC2-mediated Ca2+ signaling is required for axon extension in caudal primary motor neurons in zebrafish embryos
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Citation:
J Cell Sci. 2020;[Epub ahead of print] doi:10.1242/jcs.244780 Epub:
Not Epub Abstract:
The role of TPC2-mediated Ca2+ release was recently characterized in zebrafish during the establishment of the early spinal... Organism or Cell Type:
zebrafish Citation Extract: Guo C, Webb SE, Chan CM, Miller AL. TPC2-mediated Ca2+ signaling is required for axon extension in caudal primary motor neurons in zebrafish embryos. J Cell Sci. 2020;[Epub ahead of print] doi:10.1242/jcs.244780. |
Whole-Mount In Situ Hybridization in Zebrafish Embryos and Tube Formation Assay in iPSC-ECs to Study the Role of Endoglin in Vascular Development
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Citation:
J Vis Exp. 2020 May 28;(159). doi: 10.3791/60498 Epub:
Not Epub Abstract:
Vascular development is determined by the sequential expression of specific genes, which can be studied by performing in situ... Organism or Cell Type:
zebrafish Citation Extract: Wang Y, Zhang D, Zhou F, Zhou M, Li Q, Chen J, Yang J. Whole-Mount In Situ Hybridization in Zebrafish Embryos and Tube Formation Assay in iPSC-ECs to Study the Role of Endoglin in Vascular Development. J Vis Exp. 2020 May 28;(159). doi: 10.3791/60498. |
Connexin43 gap junctional intercellular communication inhibits evx1 expression and joint formation in regenerating fins
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Citation:
Development. 2020;[Epub ahead of print] doi:10.1242/dev.190512 Epub:
Yes Abstract:
The gap junction protein Connexin43 (Cx43) contributes to cell fate decisions that determine the location of fin ray joints... Organism or Cell Type:
zebrafish Citation Extract: Bhattacharya S, Hyland C, Falk MM, Iovine MK. Connexin43 gap junctional intercellular communication inhibits evx1 expression and joint formation in regenerating fins. Development. 2020;[Epub ahead of print] doi:10.1242/dev.190512. |
Comparative exome sequencing reveals novel candidate genes for retinitis pigmentosa
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Citation:
EBioMedicine. 2020;56:102792. doi:10.1016/j.ebiom.2020.102792 Epub:
Not Epub Abstract:
Background: Retinitis pigmentosa (RP) is the most common form of inherited retinal degeneration, but genetic defects in nearly... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yi Z, Ouyang J, Sun W, Li S, Xiao X, Zhang Q. Comparative exome sequencing reveals novel candidate genes for retinitis pigmentosa. EBioMedicine. 2020;56:102792. doi:10.1016/j.ebiom.2020.102792. |
Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos
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Citation:
Front Cell Dev Biol. 2020;8:831. doi:10.3389/fcell.2020.00381 Epub:
Not Epub Abstract:
High mitochondrial DNA (mtDNA) copy numbers are essential for oogenesis and embryogenesis and correlate with fertility of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Otten ABC, Kamps R, Lindsey P, Gerards M, Pendeville-Samain H, Muller M, van Tienen FHJ, Smeets HJM. Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos. Front Cell Dev Biol. 2020;8:831. doi:10.3389/fcell.2020.00381. |
Use Of Non-Ablative Dose Of Radiation To Enhance Delivery Of Unmodified Morpholino Oligonucleotides In A Brain Tumor Model To Silence MGMT And Enhance The Efficacy Of Chemo-Radiation (4281)
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Citation:
Neurology. 2020;94 (15 Supplement) Epub:
Not Epub Abstract:
Objective: Non-ablative Ionizing radiation ( XRT) is well known to alter neuro-vascular unit (NVU) permeability. We evaluate... Delivery Method:
injection and ionizing radiation Organism or Cell Type:
Intracranial tumor bearing athymic nude rats Citation Extract: Ambady P, Wu J, Walker J, Kersch C, Morris DA, Bills J, Holland S, Pagel M, Muldoon L, Neuwelt E. Use Of Non-Ablative Dose Of Radiation To Enhance Delivery Of Unmodified Morpholino Oligonucleotides In A Brain Tumor Model To Silence MGMT And Enhance The Efficacy Of Chemo-Radiation (4281). Neurology. 2020;94 (15 Supplement). |
Energy and nitrogenous waste from glutamate/glutamine catabolism facilitates acute osmotic adjustment in non-neuroectodermal branchial cells
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Citation:
Sci Rep. 2020;10:9460. doi:10.1038/s41598-020-65913-1 Epub:
Not Epub Abstract:
Maintenance of homeostasis is one of the most important physiological responses for animals upon osmotic perturbations.... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Huang P, Liu T, Hu MY, Casties I, Tseng Y-C. Energy and nitrogenous waste from glutamate/glutamine catabolism facilitates acute osmotic adjustment in non-neuroectodermal branchial cells. Sci Rep. 2020;10:9460. doi:10.1038/s41598-020-65913-1. |
Vertebrate Models to Investigate CCM Pathogenesis: The Zebrafish and Mouse Model
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Citation:
Methods Mol Biol. 2020;2152:225-251. doi: 10.1007/978-1-0716-0640-7_17 Epub:
Not Epub Abstract:
The use of vertebrate models allows researchers to investigate mechanisms of CCM pathogenesis in vivo, to investigate... Organism or Cell Type:
zebrafish Citation Extract: Abou-Fadel J, Zhang J. Vertebrate Models to Investigate CCM Pathogenesis: The Zebrafish and Mouse Model. Methods Mol Biol. 2020;2152:225-251. doi: 10.1007/978-1-0716-0640-7_17. |
Vascular Injury in the Zebrafish Tail Modulates Blood Flow and Peak Wall Shear Stress to Restore Embryonic Circular Network
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Citation:
Front Cardiovasc Med. 2022 Mar 18;9:841101. doi: 10.3389/fcvm.2022.841101. PMID: 35369301; PMCID: PMC8971683 Epub:
Not Epub Abstract:
Mechano-responsive signaling pathways enable blood vessels within a connected network to structurally adapt to partition of... Link:
Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Baek KI, Chang SS, Chang CC, Roustaei M, Ding Y, Wang Y, Chen J, O'Donnell R, Chen H, Ashby JW, Xu X, Mack JJ, Cavallero S, Roper M, Hsiai TK. Vascular Injury in the Zebrafish Tail Modulates Blood Flow and Peak Wall Shear Stress to Restore Embryonic Circular Network. Front Cardiovasc Med. 2022 Mar 18;9:841101. doi: 10.3389/fcvm.2022.841101. PMID: 35369301; PMCID: PMC8971683. |