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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Synonymous GATA2 mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency
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Citation:
Leukemia. 2020;[Epub]. https://doi.org/10.1038/s41375-020-0899-5 Epub:
Yes Abstract:
Deficiency of the transcription factor GATA2 is a highly penetrant genetic disorder predisposing to myelodysplastic syndromes (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kozyra EJ, Pastor VB, Lefkopoulos S. Sahoo SS, Busch H, Voss RK, Erlacher M, Lebrecht D, Szvetnik EA, Hirabayashi S, Pasaulienė R, Pedace L, Tartaglia M, Klemann C, Metzger P, Boerries M, Catala A, Hasle H, de Haas V, Kállay K, Masetti R, De Moerloose B, Dworzak M, Schmugge M, Smith O, Starý J, Mejstrikova E, Ussowicz M, Morris E, Singh P, Collin M, Derecka M, Gudrun Göhring G, Flotho C, Strahm B, Locatelli F, Niemeyer CM, Trompouki E, Wlodarski MW, European Working Group of MDS in Childhood (EWOG-MDS). Synonymous GATA2 mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency. Leukemia. 2020;[Epub]. https://doi.org/10.1038/s41375-020-0899-5. |
Pseudouridylation defect due to DKC1 and NOP10 mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis
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Citation:
Proc Nat Acad Sci USA. 2020;[Epub ahead of print] doi:10.1073/pnas.2002328117 Epub:
Yes Abstract:
RNA modifications play a fundamental role in cellular function. Pseudouridylation, the most abundant RNA modification, is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Balogh E, Chandler JC, Varga M, Tahoun M, Menyhárd DK, Schay G, Goncalves T, Hamar R, Légrádi R, Szekeres A, Gribouval O, Kleta R, Stanescu H, Bockenhauer D, Kerti A, Williams H, Kinsler V, Di W-L, Curtis D, Kolatsi-Joannou M, Hammid H, Szőcs A, Perczel K, Maka E, Toldi G, Sava F, Arrondel C, Kardos M, Fintha A, Hossain A, D’Arco F, Kaliakatsos M, Koeglmeier J, Mifsud W, Moosajee M, Faro A, Jávorszky E, Rudas G, Saied MH, Marzouk S, Kelen K, Götze J, Reusz G, Tulassay T, Dragon F, Mollet G, Motameny S, Thiele H, Dorval G, Nürnberg P, Perczel A, Szabó AJ, Long DA, Tomita K, Antignac C, Waters AM, Tory K. Pseudouridylation defect due to DKC1 and NOP10 mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis. Proc Nat Acad Sci USA. 2020;[Epub ahead of print] doi:10.1073/pnas.2002328117. |
Pre-mRNA Splicing Modulation by Antisense Oligonucleotides
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Citation:
Methods Mol Biol. 2018;1828:415-437. doi:10.1007/978-1-4939-8651-4_26 Epub:
Not Epub Abstract:
Pre-mRNA splicing, a dynamic process of intron removal and exon joining, is governed by a combinatorial control exerted by... Delivery Method:
electroporation Organism or Cell Type:
cell culture: SMA-patient-derived primary fibroblasts GM03813 Citation Extract: Singh NN, Luo D, Singh RN. Pre-mRNA Splicing Modulation by Antisense Oligonucleotides. Methods Mol Biol. 2018;1828:415-437. doi:10.1007/978-1-4939-8651-4_26. |
DNA-based fluorescent probes of NOS2 activity in live brains
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Citation:
PNAS USA. 2020;[Epub ahead of print] doi:10.1073/pnas.2003034117 Epub:
Yes Abstract:
When a pathogen is engulfed by an immune cell, it is trapped in a transient organelle called the phagosome. The host cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Veetil AT, Zou J, Henderson KW, Jani MS, Shaik SM, Sisodia SS, Hale ME, Krishnan Y. DNA-based fluorescent probes of NOS2 activity in live brains. PNAS USA. 2020;[Epub ahead of print] doi:10.1073/pnas.2003034117. |
ADP receptor P2y12 prevents excessive primitive hematopoiesis in zebrafish by inhibiting Gata1
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Citation:
Acta Pharmacol Sin. 2020;[Epub] doi:10.1038/s41401-020-0431-5 Epub:
Not Epub Abstract:
In the past two decades, purinergic signaling has emerged as a key regulator of hematopoiesis in physiological and pathological... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li F, Liang Y, Han X, Guan Y-n, Chen J, Wu P, Zhao X-x, Jing Q
. ADP receptor P2y12 prevents excessive primitive hematopoiesis in zebrafish by inhibiting Gata1. Acta Pharmacol Sin. 2020;[Epub] doi:10.1038/s41401-020-0431-5. |
Proteomic Identification Reveals the Role of Ciliary Extracellular‐Like Vesicle in Cardiovascular Function
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Citation:
Adv Sci. 2020;[Early epub] doi:10.1002/advs.201903140 Epub:
Yes Abstract:
Primary cilia are shown to have membrane swelling, also known as ciliary bulbs. However, the role of these structures and their... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mohieldin AM, Pala R, Sherpa RT, Alanazi M, Alanazi A, Shamloo K, Ahsan A, AbouAlaiwi WA, Moresco JJ. Yates JR III, Nauli SM. Proteomic Identification Reveals the Role of Ciliary Extracellular‐Like Vesicle in Cardiovascular Function. Adv Sci. 2020;[Early epub] doi:10.1002/advs.201903140. |
TPC2-mediated Ca2+ signaling is required for axon extension in caudal primary motor neurons in zebrafish embryos
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Citation:
J Cell Sci. 2020;[Epub ahead of print] doi:10.1242/jcs.244780 Epub:
Not Epub Abstract:
The role of TPC2-mediated Ca2+ release was recently characterized in zebrafish during the establishment of the early spinal... Organism or Cell Type:
zebrafish Citation Extract: Guo C, Webb SE, Chan CM, Miller AL. TPC2-mediated Ca2+ signaling is required for axon extension in caudal primary motor neurons in zebrafish embryos. J Cell Sci. 2020;[Epub ahead of print] doi:10.1242/jcs.244780. |
Whole-Mount In Situ Hybridization in Zebrafish Embryos and Tube Formation Assay in iPSC-ECs to Study the Role of Endoglin in Vascular Development
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Citation:
J Vis Exp. 2020 May 28;(159). doi: 10.3791/60498 Epub:
Not Epub Abstract:
Vascular development is determined by the sequential expression of specific genes, which can be studied by performing in situ... Organism or Cell Type:
zebrafish Citation Extract: Wang Y, Zhang D, Zhou F, Zhou M, Li Q, Chen J, Yang J. Whole-Mount In Situ Hybridization in Zebrafish Embryos and Tube Formation Assay in iPSC-ECs to Study the Role of Endoglin in Vascular Development. J Vis Exp. 2020 May 28;(159). doi: 10.3791/60498. |
Connexin43 gap junctional intercellular communication inhibits evx1 expression and joint formation in regenerating fins
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Citation:
Development. 2020;[Epub ahead of print] doi:10.1242/dev.190512 Epub:
Yes Abstract:
The gap junction protein Connexin43 (Cx43) contributes to cell fate decisions that determine the location of fin ray joints... Organism or Cell Type:
zebrafish Citation Extract: Bhattacharya S, Hyland C, Falk MM, Iovine MK. Connexin43 gap junctional intercellular communication inhibits evx1 expression and joint formation in regenerating fins. Development. 2020;[Epub ahead of print] doi:10.1242/dev.190512. |
Comparative exome sequencing reveals novel candidate genes for retinitis pigmentosa
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Citation:
EBioMedicine. 2020;56:102792. doi:10.1016/j.ebiom.2020.102792 Epub:
Not Epub Abstract:
Background: Retinitis pigmentosa (RP) is the most common form of inherited retinal degeneration, but genetic defects in nearly... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yi Z, Ouyang J, Sun W, Li S, Xiao X, Zhang Q. Comparative exome sequencing reveals novel candidate genes for retinitis pigmentosa. EBioMedicine. 2020;56:102792. doi:10.1016/j.ebiom.2020.102792. |