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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12156 scientific papers returned from the database with the search filters currently being used below.

Neutrophil Swarming in Damaged Tissue Is Orchestrated by Connexins and Cooperative Calcium Alarm Signals

Authors:
Poplimont H, Georgantzoglou A, Boulch M, Walker HA, Coombs C, Papaleonidopoulou F, Sarris M
Citation:
Curr Biol. 2020;[Epub ahead of print] doi:10.1016/j.cub.2020.05.030
Epub:
Yes
Abstract:
Neutrophils are major inflammatory cells that rapidly infiltrate wounds to provide antimicrobial functions. Within the damaged...
Link:
https://www.cell.com/current-biology/fulltext/S0960-9822(20)30669-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Poplimont H, Georgantzoglou A, Boulch M, Walker HA, Coombs C, Papaleonidopoulou F, Sarris M. Neutrophil Swarming in Damaged Tissue Is Orchestrated by Connexins and Cooperative Calcium Alarm Signals. Curr Biol. 2020;[Epub ahead of print] doi:10.1016/j.cub.2020.05.030.

LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling

Authors:
Mancini A, Howard SR, Marelli F, Cabrera CP, Barnes MR, Sternberg MJE, Leprovots M, Hadjidemetriou I, Monti E, David A, Wehkalampi K, Oleari R, Lettieri A, Vezzoli V, Vassart G, Cariboni A, Bonomi M, Garcia MI, Guasti L, Dunkel L
Citation:
JCI Insight. 2020;[Epub ahead of print] doi:10.1172/jci.insight.133434
Epub:
Yes
Abstract:
The initiation of puberty is driven by an upsurge in hypothalamic gonadotropin-releasing hormone (GnRH) secretion. In turn,...
Link:
https://insight.jci.org/articles/view/133434
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mancini A, Howard SR, Marelli F, Cabrera CP, Barnes MR, Sternberg MJE, Leprovots M, Hadjidemetriou I, Monti E, David A, Wehkalampi K, Oleari R, Lettieri A, Vezzoli V, Vassart G, Cariboni A, Bonomi M, Garcia MI, Guasti L, Dunkel L. LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling. JCI Insight. 2020;[Epub ahead of print] doi:10.1172/jci.insight.133434.

Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle

Authors:
Chestnut B, Casie Chetty S, Koenig AL, Sumanas S
Citation:
Nat Commun. 2020;11:2796. doi:10.1038/s41467-020-16515-y
Epub:
Not Epub
Abstract:
Cell fate decisions involved in vascular and hematopoietic embryonic development are still poorly understood. An ETS...
Link:
https://www.nature.com/articles/s41467-020-16515-y
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chestnut B, Casie Chetty S, Koenig AL, Sumanas S. Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle. Nat Commun. 2020;11:2796. doi:10.1038/s41467-020-16515-y.

Trim45 is essential to the development of the diencephalon and eye in zebrafish embryos

Authors:
Choe S, Huh TL, Rhee M
Citation:
Anim Cells Syst (Seoul). 2020 Apr 22;24(2):99-106. doi: 10.1080/19768354.2020.1751281
Epub:
Not Epub
Abstract:
Trim45 is one of the RING (really interesting new gene) finger containing E3 ligase, which belongs to TRIM (Tripartite motif)...
Link:
https://pubmed.ncbi.nlm.nih.gov/32489689/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Choe S, Huh TL, Rhee M. Trim45 is essential to the development of the diencephalon and eye in zebrafish embryos. Anim Cells Syst (Seoul). 2020 Apr 22;24(2):99-106. doi: 10.1080/19768354.2020.1751281.

CAMSAP3 facilitates basal body polarity and the formation of the central pair of microtubules in motile cilia

Authors:
Robinson AM, Takahashi S, Brotslaw EJ, Ahmad A, Ferrer E, Procissi D, Richter CP, Cheatham MA, Mitchell BJ, Zheng J
Citation:
Proc Natl Acad Sci U S A. 2020 Jun 1:201907335. doi: 10.1073/pnas.1907335117. Online ahead of print
Epub:
Not Epub
Abstract:
Synchronized beating of cilia on multiciliated cells (MCCs) generates a directional flow of mucus across epithelia. This...
Link:
https://www.pnas.org/content/early/2020/05/28/1907335117
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Robinson AM, Takahashi S, Brotslaw EJ, Ahmad A, Ferrer E, Procissi D, Richter CP, Cheatham MA, Mitchell BJ, Zheng J. CAMSAP3 facilitates basal body polarity and the formation of the central pair of microtubules in motile cilia. Proc Natl Acad Sci U S A. 2020 Jun 1:201907335. doi: 10.1073/pnas.1907335117. Online ahead of print.

Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions

Authors:
Veerapathiran S, Teh C, Zhu S, Kartigayen I, Korzh V, Matsudaira PT, Wohland T
Citation:
Elife. 2020 Nov 25;9:e59489. doi: 10.7554/eLife.59489. PMID: 33236989; PMCID: PMC7725503
Epub:
Not Epub
Abstract:
Wnt3 proteins are lipidated and glycosylated signaling molecules that play an important role in zebrafish neural patterning and...
Link:
https://elifesciences.org/articles/59489
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Veerapathiran S, Teh C, Zhu S, Kartigayen I, Korzh V, Matsudaira PT, Wohland T. Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions. Elife. 2020 Nov 25;9:e59489. doi: 10.7554/eLife.59489. PMID: 33236989; PMCID: PMC7725503.

Viral-Induced Alternative Splicing of Host Genes Promotes Influenza Replication

Authors:
Thompson MG, Dittmar M, Mallory MJ, Bhat P, Ferretti MB, Fontoura BM, Cherry S, Lynch KW
Citation:
Elife. 2020 Dec 3;9:e55500. doi: 10.7554/eLife.55500. PMID: 33269701; PMCID: PMC7735754
Epub:
Not Epub
Abstract:
Viral infection induces the expression of numerous host genes that impact the outcome of infection. Here, we show that...
Link:
https://elifesciences.org/articles/55500
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: A549
Citation Extract:
Thompson MG, Dittmar M, Mallory MJ, Bhat P, Ferretti MB, Fontoura BM, Cherry S, Lynch KW. Viral-Induced Alternative Splicing of Host Genes Promotes Influenza Replication. Elife. 2020 Dec 3;9:e55500. doi: 10.7554/eLife.55500. PMID: 33269701; PMCID: PMC7735754.

Role of matrix metalloproteinase-9 in neurodevelopmental deficits and experience-dependent plasticity in Xenopus laevis

Authors:
Gore SV, James EJ, Huang LC, Park JJ, Berghella A, Thompson AC, Cline HT, Aizenman CD
Citation:
Elife. 2021 Jul 20;10:e62147. doi: 10.7554/eLife.62147. PMID: 34282726; PMCID: PMC8315794
Epub:
Not Epub
Abstract:
Matrix metalloproteinase-9 (MMP-9) is a secreted endopeptidase targeting extracellular matrix proteins, creating permissive...
Link:
https://elifesciences.org/articles/62147
Delivery Method:
electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gore SV, James EJ, Huang LC, Park JJ, Berghella A, Thompson AC, Cline HT, Aizenman CD. Role of matrix metalloproteinase-9 in neurodevelopmental deficits and experience-dependent plasticity in Xenopus laevis. Elife. 2021 Jul 20;10:e62147. doi: 10.7554/eLife.62147. PMID: 34282726; PMCID: PMC8315794.

Functional characterization of a 'plant-like' HYL1 homolog in the cnidarian Nematostella vectensis indicates a conserved involvement in microRNA biogenesis

Authors:
Tripathi AM, Admoni Y, Fridrich A, Lewandowska M, Surm JM, Aharoni R, Moran Y
Citation:
Elife. 2022 Mar 15;11:e69464. doi: 10.7554/eLife.69464. PMID: 35289745; PMCID: PMC9098223
Epub:
Not Epub
Abstract:
While the biogenesis of microRNAs (miRNAs) in both animals and plants depends on the RNase III Dicer, its partner proteins are...
Link:
https://elifesciences.org/articles/69464
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (cniderian)
Citation Extract:
Tripathi AM, Admoni Y, Fridrich A, Lewandowska M, Surm JM, Aharoni R, Moran Y. Functional characterization of a 'plant-like' HYL1 homolog in the cnidarian Nematostella vectensis indicates a conserved involvement in microRNA biogenesis. Elife. 2022 Mar 15;11:e69464. doi: 10.7554/eLife.69464. PMID: 35289745; PMCID: PMC9098223.

Arginine Vasopressin Modulates Ion and Acid/Base Balance by Regulating Cell Numbers of Sodium Chloride Cotransporter and H+-ATPase Rich Ionocytes

Authors:
Tong S-K, Lee H-L, Lee Y-C, Wu L-C, Tsou Y-L, Lu S-W, Shih S-W, Hwang P-P, Chou M-Y
Citation:
Int J Mol Sci. 2020;21(11):9357. doi:10.3390/ijms21113957
Epub:
Not Epub
Abstract:
Arginine vasopressin (Avp) is a conserved pleiotropic hormone that is known to regulate both water reabsorption and ion balance...
Link:
https://www.mdpi.com/1422-0067/21/11/3957
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tong S-K, Lee H-L, Lee Y-C, Wu L-C, Tsou Y-L, Lu S-W, Shih S-W, Hwang P-P, Chou M-Y. Arginine Vasopressin Modulates Ion and Acid/Base Balance by Regulating Cell Numbers of Sodium Chloride Cotransporter and H+-ATPase Rich Ionocytes. Int J Mol Sci. 2020;21(11):9357. doi:10.3390/ijms21113957.

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