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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

HSP60 regulates monosodium urate crystal-induced inflammation by activating the TLR4-NF- κ B-MyD88 signaling pathway and disrupting mitochondrial function

Authors:
Gao W, Huang Q, Qin T, Mu H, Long F, Ren L, Tang H, Liu J, Zeng M
Citation:
Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-25061/v1
Epub:
Not Epub
Abstract:
Background: Acute gout is an inflammatory response induced by monosodium urate (MSU) crystals. HSP60 is a highly conserved...
Link:
https://www.researchsquare.com/article/rs-25061/v1
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Gao W, Huang Q, Qin T, Mu H, Long F, Ren L, Tang H, Liu J, Zeng M. HSP60 regulates monosodium urate crystal-induced inflammation by activating the TLR4-NF- κ B-MyD88 signaling pathway and disrupting mitochondrial function. Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-25061/v1.

The vertebrate-specific VENTX/NANOG gene empowers neural crest with ectomesenchyme potential

Authors:
Scerbo P, Monsoro-Burq AH
Citation:
Sci Adv. 2020;6(18):eaaz1469. doi:10.1126/sciadv.aaz1469
Epub:
Not Epub
Abstract:
During Cambrian, unipotent progenitors located at the neural (plate) border (NB) of an Olfactoria chordate embryo acquired the...
Link:
https://advances.sciencemag.org/content/6/18/eaaz1469
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Scerbo P, Monsoro-Burq AH. The vertebrate-specific VENTX/NANOG gene empowers neural crest with ectomesenchyme potential. Sci Adv. 2020;6(18):eaaz1469. doi:10.1126/sciadv.aaz1469 .

miR-103/107 regulates left-right asymmetry in zebrafish by modulating Kupffer's vesicle development and ciliogenesis

Authors:
Heigwer J, Kutzner J, Haeussler M, Burkhalter MD, Draebing T, Juergensen L, Katus HA, Philipp M, Westhoff JH, Hassel D
Citation:
Biochem Biophys Res Commun. 2020 Apr 22. pii: S0006-291X(20)30792-0. doi: 10.1016/j.bbrc.2020.04.066. [Epub ahead of print]
Epub:
Yes
Abstract:
In zebrafish, cilia movement within the Kupffer's vesicle (KV) generates a fluid flow responsible for accumulating nodal...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0006291X20307920
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Heigwer J, Kutzner J, Haeussler M, Burkhalter MD, Draebing T, Juergensen L, Katus HA, Philipp M, Westhoff JH, Hassel D. miR-103/107 regulates left-right asymmetry in zebrafish by modulating Kupffer's vesicle development and ciliogenesis. Biochem Biophys Res Commun. 2020 Apr 22. pii: S0006-291X(20)30792-0. doi: 10.1016/j.bbrc.2020.04.066. [Epub ahead of print].

Functional characterization of Neurofilament Light b splicing and misbalance in zebrafish

Authors:
Demy DL, Campanari M-L, Munoz-Ruiz R,Durham HD, Gentil B, Kabashi E
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.04.27.064063
Epub:
Not Epub
Abstract:
Neurofilaments (NFs), a major cytoskeletal component of motor neurons, play a key role in their differentiation, establishment...
Link:
https://www.biorxiv.org/content/10.1101/2020.04.27.064063v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Demy DL, Campanari M-L, Munoz-Ruiz R,Durham HD, Gentil B, Kabashi E. Functional characterization of Neurofilament Light b splicing and misbalance in zebrafish. bioRxiv. 2020;[preprint] doi:10.1101/2020.04.27.064063.

Fgf-driven Tbx protein activities directly induce myf5 and myod to initiate zebrafish myogenesis

Authors:
Osborn DPS, Li K, Cutty SJ, Nelson AC, Wardle FC, Hinits Y, Hughes SM
Citation:
Development. 2020;147(8):[Epub] doi:10.1242/dev.184689
Epub:
Not Epub
Abstract:
Skeletal muscle derives from dorsal mesoderm formed during vertebrate gastrulation. Fibroblast growth factor (Fgf) signalling...
Link:
https://dev.biologists.org/content/147/8/dev184689
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Osborn DPS, Li K, Cutty SJ, Nelson AC, Wardle FC, Hinits Y, Hughes SM. Fgf-driven Tbx protein activities directly induce myf5 and myod to initiate zebrafish myogenesis. Development. 2020;147(8):[Epub] doi:10.1242/dev.184689.

Practical Synthesis of Quinoline-Protected Morpholino Oligomers for Light-Triggered Regulation of Gene Function

Authors:
Deodato D, Dore TM
Citation:
Molecules. 2020;25(9):2078. doi:10.3390/molecules25092078
Epub:
Not Epub
Abstract:
Photoactivatable cyclic caged morpholino oligomers (ccMOs) represent a promising tool to selectively regulate gene expression...
Link:
https://www.mdpi.com/1420-3049/25/9/2078
Citation Extract:
Deodato D, Dore TM. Practical Synthesis of Quinoline-Protected Morpholino Oligomers for Light-Triggered Regulation of Gene Function. Molecules. 2020;25(9):2078. doi:10.3390/molecules25092078.

A homozygous MRPL24 mutation causes a complex movement disorder and affects the mitoribosome assembly

Authors:
Nottia MD, Marchese M, Verrigni D, Mutti C, Torraco A, Oliva R, Fernandez-Vizarra E, Morani F, Trani G, Rizza T, Ghezzi D, Ardissone A, Nesti C, Vasco G, Zeviani M, Minczuk M, Bertini E, Santorelli FM, Carrozzo R
Citation:
Neurobiol Dis. 2020 Apr 25:104880. doi: 10.1016/j.nbd.2020.104880. [Epub ahead of print]
Epub:
Yes
Abstract:
Mitochondrial ribosomal protein large 24 (MRPL24) is 1 of the 82 protein components of mitochondrial ribosomes, playing an...
Link:
https://www.sciencedirect.com/science/article/pii/S0969996120301558
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nottia MD, Marchese M, Verrigni D, Mutti C, Torraco A, Oliva R, Fernandez-Vizarra E, Morani F, Trani G, Rizza T, Ghezzi D, Ardissone A, Nesti C, Vasco G, Zeviani M, Minczuk M, Bertini E, Santorelli FM, Carrozzo R. A homozygous MRPL24 mutation causes a complex movement disorder and affects the mitoribosome assembly. Neurobiol Dis. 2020 Apr 25:104880. doi: 10.1016/j.nbd.2020.104880. [Epub ahead of print].

Mis12 controls cyclin B1 stabilization via Cdc14B-mediated APC/CCdh1 regulation during meiotic G2/M transition in mouse oocytes

Authors:
Bai G-Y, Choe MH, Kim J-S, Oh JS
Citation:
Development. 2020;147(8):[Epub ahead of print] doi:10.1242/dev.185322
Epub:
Yes
Abstract:
Mammalian oocytes are arrested at G2/prophase of the first meiosis. After a hormone surge, oocytes resume meiosis, undergoing...
Link:
https://dev.biologists.org/content/147/8/dev185322
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Bai G-Y, Choe MH, Kim J-S, Oh JS. Mis12 controls cyclin B1 stabilization via Cdc14B-mediated APC/CCdh1 regulation during meiotic G2/M transition in mouse oocytes. Development. 2020;147(8):[Epub ahead of print] doi:10.1242/dev.185322.

Role of kif2c, A Gene Related to ALL Relapse, in Embryonic Hematopoiesis in Zebrafish

Authors:
Oh C-K, Kang JW, Lee Y, Myung K, Ha M, Kang J, Kwon EJ, Kim Y, Oh S-O, Heo HJ, Kim S, Kim YH
Citation:
Int J Molec Sci. 2020;21(9):3127. doi:10.3390/ijms21093127
Epub:
Not Epub
Abstract:
Relapse of acute lymphoblastic leukemia (ALL) is dangerous and it worsens the prognosis of patients; however, prognostic...
Link:
https://www.mdpi.com/1422-0067/21/9/3127
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Oh C-K, Kang JW, Lee Y, Myung K, Ha M, Kang J, Kwon EJ, Kim Y, Oh S-O, Heo HJ, Kim S, Kim YH. Role of kif2c, A Gene Related to ALL Relapse, in Embryonic Hematopoiesis in Zebrafish. Int J Molec Sci. 2020;21(9):3127. doi:10.3390/ijms21093127.

Nodal and Planar Cell Polarity signaling cooperate to regulate zebrafish convergence and extension gastrulation movements

Authors:
Williams MLK, Solnica-Krezel L
Citation:
Elife. 2020 Apr 22;9. pii: e54445. doi: 10.7554/eLife.54445. [Epub ahead of print]
Epub:
Not Epub
Abstract:
During vertebrate gastrulation, convergence & extension (C&E) of the primary anteroposterior (AP) embryonic axis is...
Link:
https://elifesciences.org/articles/54445
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Williams MLK, Solnica-Krezel L. Nodal and Planar Cell Polarity signaling cooperate to regulate zebrafish convergence and extension gastrulation movements. Elife. 2020 Apr 22;9. pii: e54445. doi: 10.7554/eLife.54445. [Epub ahead of print].

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